The management of pain in metastatic bone disease

Cancer Control

Volumn 19, Issue 2, 2012, Pages 154-166

  Buga, Sorin ^a   Sarria, Jose E ^a  

^a H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANALGESIC AGENT; BISPHOSPHONIC ACID DERIVATIVE; CALCITONIN; CORTICOSTEROID; DENOSUMAB; DEXAMETHASONE; KETAMINE; METHADONE; OMEGA CONOTOXIN MVIIA; ZOLEDRONIC ACID;

BONE METASTASIS; BONE PAIN; CANCER HORMONE THERAPY; CANCER PAIN; CANCER RADIOTHERAPY; CATHETER INFECTION; CATHETER OCCLUSION; CHIROPRACTIC; COMPRESSION FRACTURE; CONSERVATIVE TREATMENT; CRYOTHERAPY; EXTERNAL BEAM RADIOTHERAPY; HUMAN; HYPERTHERMIC THERAPY; INTERMETHOD COMPARISON; KINESIOTHERAPY; KYPHOPLASTY; NEOPLASM; NEUROPATHIC PAIN; NONHUMAN; OSTEOPATHIC MEDICINE; PAIN ASSESSMENT; PATHOPHYSIOLOGY; QUALITY OF LIFE; RELAXATION TRAINING; REVIEW; SPINAL CORD STIMULATION; TRANSCUTANEOUS NERVE STIMULATION; UNSPECIFIED SIDE EFFECT; VERTEBRA FRACTURE;

EID: 84859452767     PISSN: 10732748     EISSN: 15262359     Source Type: Journal    
DOI: 10.1177/107327481201900210     Document Type: Review

References (102)

1. Grond S, Zech D, Diefenbach C, et al. Assessment of cancer pain: a prospective evaluation in 2266 cancer patients referred to a pain service. Pain. 1996;64(1):107-114.
2. Twycross R, Harcourt J, Bergl S. A survey of pain in patients with advanced cancer. J Pain Symptom Manage. 1996;12(5):273-282.
3. Mercadante S. Malignant bone pain: pathophysiology and treatment. Pain. 1997;69:1-18.
4. Schwei MJ, Honore P, Rogers SD, et al. Neurochemical and cellular reorganization of the spinal cord in a murine model of bone cancer pain. J Neurosci. 1999;19(24):10886-10897.
5. Kidd BL, Urban LA. Mechanisms of inflammatory pain. Br J Anaesth. 2001;87(1):3-11.
6. Delaissé J-M, Vaes G. Mechanisms of mineral solubilization and matrix degradation in osteoblastic bone resorption. In: Rifkin BR, Gay CV, eds. Biology and Physiology of the Osteoclast. CRC Press, Inc: Boca Raton, FL; 1992:289-314.
7. Mantyh PW, Clohisy DR, Koltzenburg M, et al. Molecular mechanisms of cancer pain. Nat Rev Cancer. 2002;2(3):201-209.
8. Jacox AK, Carr DB, Payne R, et al. Management of cancer pain. Clinical practice guideline no. 9. Rockville, MD: Agency for Health Care Policy and Research. AHCPR Publication no. 94-0592;1994.
9. Robb K, Oxberry SG, Bennett MI, et al. A cochrane systematic review of transcutaneous electrical nerve stimulation for cancer pain. J Pain Symptom Manage. 2009;37(4):746-753.
10. Carroll D, Moore RA, McQuay HJ, et al. Transcutaneous electrical nerve stimulation (TENS) for chronic pain. Cochrane Database Syst Rev. 2001;(3):CD003222.
11. Jane SW, Wilkie DJ, Gallucci BB, et al. Effects of a full-body massage on pain intensity, anxiety, and physiological relaxation in Taiwanese patients with metastatic bone pain: a pilot study. J Pain Symptom Manage. 2009;37(4):754-763.
12. Elkins G, Fisher W, Johnson A. Mind-body therapies in integrative oncology. Curr Treat Options Oncol. 2010;11(3-4):128-140.
13. Butler LD, Koopman C, Neri E, et al. Effects of supportive-expressive group therapy on pain in women with metastatic breast cancer. Health Psychol. 2009;28(5):579-587.
14. Sohl SJ, Stossel L, Schnur JB, et al. Intentions to use hypnosis to control the side effects of cancer and its treatment. Am J Clin Hypn. 2010;53(2):93-100.
15. Martinez-Zapata MJ, Roqué M, Alonso-Coello P, et al. Calcitonin for metastatic bone pain. Cochrane Database Syst Rev. 2006;3:CD003223.
16. Wong R, Wiffen PJ. Bisphosphonates for the relief of pain secondary to bone metastases. Cochrane Database Syst Rev. 2002;(2):CD002068.
17. Niang U, Kamer S, Ozsaran Z, et al. The management of painful bone metastases with biphosphonates and palliative radiotherapy: a retrospective evaluation of 372 cases. J BUON. 2009;14(2):245-249.
18. Zarogoulidis K, Boutsikou E, Zarogoulidis P, et al. The impact of zoledronic acid therapy in survival of lung cancer patients with bone metastasis. Int J Cancer. 2009;125(7):1705-1709.
19. Saad F. New research findings on zoledronic acid: survival, pain, and anti-tumour effects. Cancer Treat Rev. 2008;34(2):183-192.
20. Fizazi K, Carducci M, Smith M, et al. Denosumab versus zoledronic acid for treatment of bone metastases in men with castrationresistant prostate cancer: a randomized, double-blind study. Lancet. 2011;377(9768):813-822.
21. Stopeck AT, Lipton A, Body JJ, et al. Denosumab compared with zoledronic acid for the treatment of bone metastases in patients with advanced breast cancer: a randomized, double-blind study. J Clin Oncol. 2010;28(35):5132-5139.
22. Henry DH, Costa L, Goldwasser F, et al. Randomized, double-blind study of denosumab versus zoledronic acid in the treatment of bone metastases in patients with advanced cancer (excluding breast and prostate cancer) or multiple myeloma. J Clin Oncol. 2011;29(9):1125-1132.
23. Hird A, Zhang L, Holt T, et al. Dexamethasone for the prophylaxis of radiation-induced pain flare after palliative radiotherapy for symptomatic bone metastases: a phase II study. Clin Oncol (R Coll Radiol). 2009;21(4):329-335.
24. Ventafridda V, Tamburini M, Caraceni A, et al. A validation study of the WHO method for cancer pain relief. Cancer. 1987;59(4):850-856.
25. Walker VA, Hoskin PJ, Hanks GW, et al. Evaluation of WHO analgesic guidelines for cancer pain in a hospital-based palliative care unit. J Pain Symptom Manage. 1988;3(3):145-149.
26. American Geriatrics Society Panel on Pharmacological Management of Persistent Pain in Older Persons. Pharmacological management of persistent pain in older persons. J Am Geriatric Soc. 2009;57(8):1331-1346.
27. Portenoy RK, Hagen NA. Breakthrough pain: definition, prevalence and characteristics. Pain. 1990;41(3):273-281.
28. Mercadante S. Pharmacotherapy for breakthrough cancer pain. Drugs. 2012;72(2):181-190.
29. Mercadante S, Villari P, Ferrera P, et al. Opioid switching and burst Ketamine to improve the opioid response in patients with movement-related pain due to bone metastases. Clin J Pain. 2009;25(7):648-649.
30. Gomez-Batiste X, Madrid F, Moreno F, et al. Breakthrough cancer pain: prevalence and characteristics in patients in Catalonia, Spain. J Pain Symptom Manage. 2002;24(1):45-52.
31. Hwang SS, Chang VT, Kasimis B. Cancer breakthrough pain characteristics and responses to treatment at a VA medical center. Pain. 2003;101(1-2):55-64.
32. Payne R. Recognition and diagnosis of breakthrough pain. Pain Med. 2007;8(suppl 1):S3-S7.
33. Elsner F, Zeppetella G, Porta-Sales J, et al. Newer generation fentanyl transmucosal products for breakthrough pain in opioid-tolerant cancer patients. Clin Drug Investig. 2011;31(9):605-618.
34. Chazan S, Ekstein MP, Marouani N, et al. Ketamine for acute and subacute pain in opioid-tolerant patients. J Opioid Manag. 2008;4(3):173-180.
35. de Cremoux P. Hormone therapy and breast cancer. Bull Cancer. 2011;98(11):1311-1319.
36. Prat A, Baselga J. The role of hormonal therapy in the management of hormonal-receptor-positive breast cancer with co-expression of HER2. Nat Clin Pract Oncol. 2008;5(9):531-542.
37. Dayyani F, Gallick GE, Logothetis CJ, et al. Novel therapies for metastatic castrate-resistant prostate cancer. J Natl Cancer Inst. 2011;103(22):1665-1675.
38. World Health Organization. WHO draft interim guidelines handbook on relief of cancer pain. Report of a WHO Consultation, Milan, 14-16 October, 1982. WHO CAN/84.2.
39. McInnes C. Cancer ward. New Society. 1976;36:232-234.
40. Jadad AR, Browman GP. The WHO analgesic ladder for cancer pain management: stepping up the quality of its evaluation. JAMA. 1995;274(23):1870-1873.
41. Ahmedzai S. New approaches to pain control in patients with cancer. Eur J Cancer. 1997;33(suppl 6):S8-S14.
42. Miguel R. Interventional treatment of cancer pain: the fourth step in the World Health Organization analgesic ladder? Cancer Control. 2000;7(2):149-156.
43. Khoromi S, Cui L, Nackers L, et al. Morphine, Nortriptyline and their combination vs placebo in patients with chronic lumbar root pain. Pain. 2007;130 (1-2):66-75.
44. Dworkin RH, O'Connor AB, Audette J, et al. Recommendations for the pharmacological management of neuropathic pain: an overview and literature update. Mayo Clin Proc. 2010;85(3 suppl):S3-S14.
45. Lee M, Silverman SM, Hansen H, et al. Comprehensive review of opioid-induced hyperalgesia. Pain Physician. 2011;14(2):145-161.
46. Ballantyne JC, Mao J. Opioid therapy for chronic pain. N Engl J Med. 2003;349:1943-1953.
47. Starr TD, Rogak LJ, Passik SD. Substance abuse in cancer pain. Curr Pain Headache Rep. 2010;14(4):268-275.
48. Burton AW, Fanciullo GJ, Beasley RD, et al. Chronic pain in the cancer survivor: a new frontier. Pain Med. 2007;8(2):189-198.
49. Burton AW, Hamid B. Current challenges in cancer pain management: does the WHO ladder approach still have relevance? Expert Rev Anticancer Ther. 2007;7(11):1501-1502.
50. Bach F, Larsen BH, Rohde K, et al. Metastatic spinal cord compression. Occurrence, symptoms, clinical presentations and prognosis in 398 patients with spinal cord compression. Acta Neurochir (Wien). 1990;107(1-2):37-43.
51. White AP, Kwon BK, Lindskog DM, at al. Metastatic disease of the spine. J Am Acad Orthop Surg. 2006;14(11):587-598.
52. Gabriel K, Schiff D. Metastatic spinal cord compression by solid tumors. Semin Neurol. 2004;24(4):375-383.
53. Helweg-Larsen S, Sørensen PS. Symptoms and signs in metastatic spinal cord compression: a study of progression from first symptom until diagnosis in 153 patients. Eur J Cancer. 1994;30A (3):396-398.
54. Sciubba DM, Nguyen T, Gokaslan ZL. Solitary vertebral metastasis. Orthop Clin N Am. 2009;40:145-154.
55. Lutz S, Berk L, Chang E, et al. Palliative radiotherapy for bone metastases: an ASTRO evidence-based guideline. Int J Radiat Oncol Biol Phys. 2011;79(4):965-976.
56. Eck JC, Nachtigall D, Humphreys SC, et al. Comparison of vertebroplasty and balloon kyphoplasty for treatment of vertebral compression fractures: a meta-analysis of the literature. Spine. 2008;8(3):488-497.
57. Galibert P, Deramond H, Rosat P, et al. Preliminary note on the treatment of vertebral angioma by percutaneous acrylic vertebroplasty. Neurochirugie. 1987;33(2):166-168.
58. Wardlaw D, Cummings SR, Van Meirhaeghe J, et al. Efficacy and safety of balloon kyphoplasty compared with non-surgical care for vertebral compression fracture (FREE): a randomized controlled trial. Lancet. 2009; 373:1016-1024.
59. Kallmes DF, Comstock BA, Heagerty PJ, et al. A randomized trial of vertebroplasty for osteoporotic spinal fractures. N Engl J Med. 2009;361 (6):569-579.
60. Berenson J, Pflugmacher R, Jarzem P, et al. Balloon kyphoplasty versus non-surgical fracture management for treatment of painful vertebral body compression fractures in patients with cancer: a multicenter, randomized controlled trial. Lancet Oncol. 2011;12(3):225-235.
61. Langdon J, Bernard J, Molloy S. Prophylactic stabilization of vertebral body metastasis at risk of imminent fracture using balloon kyphoplasty. Spine. 2009;34(13):E469-E479.
62. Dupuy DE, Liu D, Hartfeil D, et al. Percutaneous radiofrequency ablation of painful osseous metastases: a multicenter American College of Radiology Imaging Network trial. Cancer. 2010;116(4):989-997.
63. Shimony JS. Percutaneous vertebroplasty for malignant compression fractures with epidural involvement. Radiology. 2004;232(3):846-853.
64. Saliou G, Kocheida el M, Lehmann P, et al. Percutaneous vertebroplasty for pain management in malignant fractures of the spine with epidural involvement. Radiology. 2010;254(3):882-890.
65. Sandri A, Carbognin G, Regis D, et al. Combined radiofrequency and kyphoplasty in painful osteolytic metastases to vertebral bodies. Radiol Med. 2010;115(2):261-271.
66. Proschek D, Kurth A, Proschek P, et al. Prospective pilot-study of combined bipolar radiofrequency ablation and application of bone cement in bone metastases. Anticancer Res. 2009;29(7):2787-2792.
67. Gerszten PC, Germanwala A, Burton SA, et al. Combination kyphoplasty and spinal radiosurgery: a new treatment paradigm for pathological fractures. J Neurosurg Spine. 2005;3(4):296-301.
68. Schneider F, Greineck F, Clausen S, et al. Development of a novel method for intraoperative radiotherapy during kyphoplasty for spinal metastases (Kypho-IORT). Int J Radiat Oncol Biol Phys. 2011;81(4):1114-1119.
69. Wenz F, Schneider F, Neumaier C, et al. Kypho-IORT - a novel approach of intraoperative radiotherapy during kyphoplasty for vertebral metastases. Radiat Oncol. 2010;5:11.
70. Burton AW, Rhines LD, Mendel E. Vertebroplasty and kyphoplasty: a comprehensive review. Neurosurg Focus. 2005;18(3):e1.
71. Georgy BA. Interventional techniques in managing persistent pain after vertebral augmentation procedures: a retrospective evaluation. Pain Physician. 2007;10(5):673-676.
72. Prather H, Watson JO, Gilula LA. Nonoperative management of osteoporotic vertebral compression fractures. Injury. 2007;38(suppl 3):S40-A48.
73. Maccauro G, Liuzza F, Scaramuzzo L, et al. Percutaneous acetabuloplasty for metastatic acetabular lesions. BMC Musculoskelet Disord. 2008;9:66.
74. Anselmetti GC, Manca A, Ortega C, et al. Treatment of extraspinal painful bone metastases with percutaneous cementoplasty: a prospective study of 50 patients. Cardiovasc Intervent Radiol. 2008;31(6):1165-1173.
75. Hoffmann RT, Jakobs TF, Trumm C, et al. Radiofrequency ablation in combination with osteoplasty in the treatment of painful metastatic bone disease. J Vasc Interv Radiol. 2008;19(3):419-425.
76. Ramanavarapu V, Simopoulos TT. Pulsed radiofrequency of lumbar dorsal root ganglia for chronic post-amputation stump pain. Pain Physician. 2008;11(4):561-566.
77. Wilkes D, Ganceres N, Solanki D, et al. Pulsed radiofrequency treatment of lower extremity phantom limb pain. Clin J Pain. 2008;24(8):736-739.
78. Cohen SP, Sireci A, Wu CL, et al. Pulsed radiofrequency of the dorsal root ganglia is superior to pharmacotherapy or pulsed radiofrequency of the intercostal nerves in the treatment of chronic postsurgical thoracic pain. Pain Physician. 2006;9(3):227-235.
79. Zeldin A, Ioscovich A. Pulsed radiofrequency for metastatic pain treatment. Pain Physician. 2008;11(6):921-922.
80. Gofeld M, Bhatia A. Alleviation of Pancoast's tumor pain by ultrasound- guided percutaneous ablation of cervical nerve roots. Pain Pract. 2008;8(4):314-319.
81. Nitescu P, Sjöberg M, Appelgren L, et al. Complications of intrathecal opioids and bupivacaine in the treatment of "refractory" cancer pain. Clin J Pain. 1995;11(1):45-46.
82. Strafford MA, Wilder RT, Berde CB. The risk of infection from epidural analgesia in children: a review of 1620 cases. Anesth Analg. 1995;80(2):234-238.
83. Aram L, Krane EJ, Kozloski LJ, et al. Tunneled epidural catheters for prolonged analgesia in pediatric patients. Anesth Analg. 2001;92(6):1432-1438.
84. Anghelescu DL, Faughnan LG, Baker JN, et al. Use of epidural and peripheral nerve blocks at the end of life in children and young adults with cancer: the collaboration between a pain service and a palliative care service. Paediatr Anaesth. 2010;20(12):1070-1077.
85. Esch AT, Esch A, Knorr JL, et al. Long-term ambulatory continuous nerve blocks for terminally ill patients: a case series. Pain Med. 2010;11(8):1299-1302.
86. Pacenta HL, Kaddoum RN, Pereiras LA, et al. Continuous tunneled femoral nerve block for palliative care of a patient with metastatic osteosarcoma. Anaesth Intensive Care. 2010;38(3):563-565.
87. Terrier G, Ranoux D, Bourzeix JV, et al. Continuous nerve blocks in the management of bone pain due to compression by cancer metastasis: place in palliative care units. J Palliat Care. 2008;24(3):190-191.
88. Nadig M, Ekatodramis G, Borgeat A. Continuous brachial plexus block at the cervical level using a posterior approach in the management of neuropathic cancer pain. Reg Anesth Pain Med. 2002;27(4):446.
89. Cuvillon P, Ripart J, Lalourcey L, et al. The continuous femoral nerve block catheter for postoperative analgesia: bacterial colonization, infectious rate and adverse effects. Anesth Analg. 2001;93(4):1045-1049.
90. Cousins MJ, Mather LE. Intrathecal and epidural administration of opioids. Anesthesiology. 1984;61(3):276-310.
91. Smith DE. Spinal opioids in the home and hospice setting. J Pain Symptom Manage. 1990;5(3):175-182.
92. Shealy CN, Mortimer JT, Reswick JB. Electrical inhibition of pain by stimulation of the dorsal columns: preliminary clinical report. Anesth Analg. 1967;46(4):489-491.
93. Melzack R, Wall PD. Pain mechanisms: a new theory. Science. 1965;150(3699):971-979.
94. Yakovlev AE, Resch BE, Karasev SA. Treatment of cancer-related chest wall pain using spinal cord stimulation. Am J Hosp Palliat Care. 2010;27(8):552-556.
95. Viswanathan A, Phan PC, Burton AW. Use of spinal cord stimulation in the treatment of phantom limb pain: case series and review of the literature. Pain Pract. 2010;10(5):479-484.
96. Yakovlev AE, Ellias Y. Spinal cord stimulation as a treatment option for intractable neuropathic cancer pain. Clin Med Res. 2008;6(3-4):103-106.
97. Wang JK, Nauss LA, Thomas JE. Pain relief by intrathecally applied morphine in man. Anesthesiology. 1979;50(2):149-151.
98. Cohen SP, Dragovich A. Intrathecal analgesia. Anesthesiology Clin. 2007;25(4):863-882.
99. Smith TJ, Staats PS, Deer T, et al. Randomized clinical trial of an implantable drug delivery system compared with comprehensive medical management for refractory cancer pain: impact on pain, drug-related toxicity, and survival. J Clin Oncol. 2002;20(19):4040-4049.
100. Krames ES. Intrathecal infusion therapies for intractable pain: patient management guidelines. J Pain Symptom Manage. 1993;8(1):36-46.
101. Staats PS, Yearwood T, Charapata SG, et al. Intrathecal ziconotide in the treatment of refractory pain in patients with cancer or AIDS: a randomized controlled trial. JAMA. 2004;291(1):63-70.
102. Hassenbusch SJ, Portenoy RK, Cousins M, et al. Polyanalgesic Consensus Conference 2003: an update on the management of pain by intraspinal drug delivery: report of an expert panel. J Pain Symptom Manage. 2004;27(6):540-563.