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Volumn 18, Issue 2, 2012, Pages 208-212

Treatment of melanoma brain metastases: A new paradigm

Author keywords

BRAF inhibitors; BRAF mutant; brain metastases; dabrafenib; GSK2118436; ipilimumab; Metastatic melanoma; stage IV melanoma; stereotactic radiosurgery; vemurafenib; whole brain radiotherapy

Indexed keywords

CORTICOSTEROID; DABRAFENIB; DACARBAZINE; FOTEMUSTINE; INTERLEUKIN 2; IPILIMUMAB; TEMOZOLOMIDE; VEMURAFENIB;

EID: 84859447241     PISSN: 15289117     EISSN: 1540336X     Source Type: Journal    
DOI: 10.1097/PPO.0b013e31824b2890     Document Type: Review
Times cited : (46)

References (57)
  • 1
    • 4344609724 scopus 로고    scopus 로고
    • The treatment of brain metastases in melanoma patients
    • DOI 10.1016/j.ctrv.2004.05.001, PII S0305737204000945
    • Bafaloukos D, Gogas H. The treatment of brain metastases in melanoma patients. Cancer Treat Rev. 2004;30:515-520. (Pubitemid 39157852)
    • (2004) Cancer Treatment Reviews , vol.30 , Issue.6 , pp. 515-520
    • Bafaloukos, D.1    Gogas, H.2
  • 2
    • 79953781233 scopus 로고    scopus 로고
    • Prognostic factors for survival in melanoma patients with brain metastases
    • Davies MA, Liu P, McIntyre S, et al. Prognostic factors for survival in melanoma patients with brain metastases. Cancer. 2011;117:1687-1696.
    • (2011) Cancer. , vol.117 , pp. 1687-1696
    • Davies, M.A.1    Liu, P.2    McIntyre, S.3
  • 3
    • 84861053634 scopus 로고    scopus 로고
    • Differences between Australia (OZ) and the United States (US) in the Patterns Prognosis and treatment of melanoma CNS metastases: Analysis from the PHAMOUS (prognostic heterogeneity in patients with advanced melanoma between OZ and the US) study
    • Carlino MS, Atkins MB, Warneke CL, et al. Differences between Australia (OZ) and the United States (US) in the Patterns, Prognosis, and treatment of melanoma CNS metastases: analysis from the PHAMOUS (prognostic heterogeneity in patients with advanced melanoma between OZ and the US) study. Pigment Cell Melanoma Res. 2010;23:946.
    • (2010) Pigment Cell Melanoma Res. , vol.23 , pp. 946
    • Carlino, M.S.1    Atkins, M.B.2    Warneke, C.L.3
  • 4
    • 0018096512 scopus 로고
    • Malignant melanoma and central nervous system metastases. Incidence, diagnosis, treatment and survival
    • Amer MH, Al-Sarraf M, Baker LH, et al. Malignant melanoma and central nervous system metastases: incidence, diagnosis, treatment and survival. Cancer. 1978;42:660-668. (Pubitemid 8405861)
    • (1978) Cancer , vol.42 , Issue.2 , pp. 660-668
    • Amer, M.H.1    Al-Sarraf, M.2    Baker, L.H.3    Vaitkevicius, V.K.4
  • 5
    • 0020563638 scopus 로고
    • Patterned distribution of metastases from malignant melanoma in humans
    • de la Monte SM, Moore GW, Hutchins GM. Patterned distribution of metastases from malignant melanoma in humans. Cancer Res. 1983; 43:3427-3433. (Pubitemid 13061609)
    • (1983) Cancer Research , vol.43 , Issue.7 , pp. 3427-3433
    • De La Monte, S.M.1    Moore, G.W.2    Hutchins, G.M.3
  • 6
    • 0026606221 scopus 로고
    • Cerebral metastases from malignant melanoma
    • Stevens G, Firth I, Coates A. Cerebral metastases from malignant melanoma. Radiother Oncol. 1992;23:185-191.
    • (1992) Radiother Oncol. , vol.23 , pp. 185-191
    • Stevens, G.1    Firth, I.2    Coates, A.3
  • 8
    • 77950860801 scopus 로고    scopus 로고
    • Determinants of survival in patients with brain metastases from cutaneous melanoma
    • Staudt M, Lasithiotakis K, Leiter U, et al. Determinants of survival in patients with brain metastases from cutaneous melanoma. Br J Cancer. 2010;102:1213-1218.
    • (2010) Br J Cancer. , vol.102 , pp. 1213-1218
    • Staudt, M.1    Lasithiotakis, K.2    Leiter, U.3
  • 9
    • 79953785848 scopus 로고    scopus 로고
    • Clinical variables and primary tumor characteristics predictive of the development of melanoma brain metastases and post-brain metastases survival
    • Zakrzewski J, Geraghty LN, Rose AE, et al. Clinical variables and primary tumor characteristics predictive of the development of melanoma brain metastases and post-brain metastases survival. Cancer. 2011;117: 1711-1720.
    • (2011) Cancer. , vol.117 , pp. 1711-1720
    • Zakrzewski, J.1    Geraghty, L.N.2    Rose, A.E.3
  • 10
    • 0031975369 scopus 로고    scopus 로고
    • Demographics, prognosis, and therapy in 702 patients with brain metastases from malignant melanoma
    • Sampson JH, Carter JH Jr, Friedman AH, et al. Demographics, prognosis, and therapy in 702 patients with brain metastases from malignant melanoma. J Neurosurg. 1998;88:11-20. (Pubitemid 28018958)
    • (1998) Journal of Neurosurgery , vol.88 , Issue.1 , pp. 11-20
    • Sampson, J.H.1    Carter Jr., J.H.2    Friedman, A.H.3    Seigler, B.F.4
  • 11
    • 79953799396 scopus 로고    scopus 로고
    • Number of metastases, serum lactate dehydrogenase level, and type of treatment are prognostic factors in patients with brain metastases of malignant melanoma
    • Eigentler TK, Figl A, Krex D, et al. Number of metastases, serum lactate dehydrogenase level, and type of treatment are prognostic factors in patients with brain metastases of malignant melanoma. Cancer. 2011; 117:1697-1703.
    • (2011) Cancer. , vol.117 , pp. 1697-1703
    • Eigentler, T.K.1    Figl, A.2    Krex, D.3
  • 13
    • 80052552359 scopus 로고    scopus 로고
    • Clinical characteristics and outcomes associated with BRAF and NRAS mutations in metastatic melanoma
    • Jakob JA, Bassett RL, Ng CS, et al. Clinical characteristics and outcomes associated with BRAF and NRAS mutations in metastatic melanoma. J Clin Oncol. 2011;29[suppl]: Abstract 8500.
    • (2011) J Clin Oncol. , vol.29 , Issue.SUPPL. , pp. 8500
    • Jakob, J.A.1    Bassett, R.L.2    Ng, C.S.3
  • 14
    • 0036123571 scopus 로고    scopus 로고
    • Surgical management of cerebral metastases from melanoma: Outcome in 147 patients treated at a single institution over two decades
    • Zacest AC, Besser M, Stevens G, et al. Surgical management of cerebral metastases from melanoma: outcome in 147 patients treated at a single institution over two decades. J Neurosurg. 2002;96:552-558. (Pubitemid 34230211)
    • (2002) Journal of Neurosurgery , vol.96 , Issue.3 , pp. 552-558
    • Zacest, A.C.1    Besser, M.2    Stevens, G.3    Thompson, J.F.4    McCarthy, W.H.5    Culjak, G.6
  • 17
    • 4644364818 scopus 로고    scopus 로고
    • A prognostic index that predicts outcome following palliative whole brain radiotherapy for patients with metastatic malignant melanoma
    • DOI 10.1038/sj.bjc.6602018
    • Morris SL, Low SH, A'Hern RP, et al. A prognostic index that predicts outcome following palliative whole brain radiotherapy for patients with metastatic malignant melanoma. Br J Cancer. 2004;91:829-833. (Pubitemid 39273770)
    • (2004) British Journal of Cancer , vol.91 , Issue.5 , pp. 829-833
    • Morris, S.L.1    Low, S.H.2    A'Hern, R.P.3    Eisen, T.G.4    Gore, M.E.5    Nutting, C.M.6    Harrington, K.J.7
  • 18
    • 75049085353 scopus 로고    scopus 로고
    • The role of steroids in the management of brain metastases: A systematic review and evidence-based clinical practice guideline
    • Ryken TC, McDermott M, Robinson PD, et al. The role of steroids in the management of brain metastases: a systematic review and evidence-based clinical practice guideline. J Neurooncol. 2010;96: 103-114.
    • (2010) J Neurooncol. , vol.96 , pp. 103-114
    • Ryken, T.C.1    McDermott, M.2    Robinson, P.D.3
  • 19
    • 75049083280 scopus 로고    scopus 로고
    • The role of prophylactic anticonvulsants in the management of brain metastases: A systematic review and evidence-based clinical practice guideline
    • Mikkelsen T, Paleologos NA, Robinson PD, et al. The role of prophylactic anticonvulsants in the management of brain metastases: a systematic review and evidence-based clinical practice guideline. J Neurooncol. 2010;96:97-102.
    • (2010) J Neurooncol. , vol.96 , pp. 97-102
    • Mikkelsen, T.1    Paleologos, N.A.2    Robinson, P.D.3
  • 20
    • 44849122610 scopus 로고    scopus 로고
    • Brain and leptomeningeal me-tastases from cutaneous melanoma: Survival outcomes based on clinical features
    • Raizer JJ, Hwu WJ, Panageas KS, et al. Brain and leptomeningeal me-tastases from cutaneous melanoma: survival outcomes based on clinical features. Neuro Oncol. 2008;10:199-207.
    • (2008) Neuro Oncol. , vol.10 , pp. 199-207
    • Raizer, J.J.1    Hwu, W.J.2    Panageas, K.S.3
  • 21
    • 77950246403 scopus 로고    scopus 로고
    • Stereotactic radiosurgery for the management of brain metast-ases
    • Suh JH. Stereotactic radiosurgery for the management of brain metast-ases. N Engl J Med. 2010;362:1119-1127.
    • (2010) N Engl J Med. , vol.362 , pp. 1119-1127
    • Suh, J.H.1
  • 24
    • 10144261882 scopus 로고    scopus 로고
    • A randomized trial to assess the efficacy of surgery in addition to radiotherapy in patients with a single cerebral metastasis
    • DOI 10.1002/(SICI)1097-0142(19961001)78:7<1470::AID-CNCR14>3.0. CO;2-X
    • Mintz AH, Kestle J, Rathbone MP, et al. A randomized trial to assess the efficacy of surgery in addition to radiotherapy in patients with a single cerebral metastasis. Cancer. 1996;78:1470-1476. (Pubitemid 26317868)
    • (1996) Cancer , vol.78 , Issue.7 , pp. 1470-1476
    • Mintz, A.H.1    Kestle, J.2    Rathbone, M.P.3    Gaspar, L.4    Hugenholtz, H.5    Fisher, B.6    Duncan, G.7    Skingley, P.8    Foster, G.9    Levine, M.10
  • 26
    • 48049113523 scopus 로고    scopus 로고
    • Microsurgery plus whole brain irradiation versus gamma knife surgery alone for treatment of single metastases to the brain: A randomized controlled multicentre phase III trial
    • Muacevic A, Wowra B, Siefert A, et al. Microsurgery plus whole brain irradiation versus gamma knife surgery alone for treatment of single metastases to the brain: a randomized controlled multicentre phase III trial. J Neurooncol. 2007;87:299-307.
    • (2007) J Neurooncol. , vol.87 , pp. 299-307
    • Muacevic, A.1    Wowra, B.2    Siefert, A.3
  • 29
    • 0015077786 scopus 로고
    • The radiation response of human malignant melanoma cells grown in vitro
    • Barranco SC, Romsdahl MM, Humphrey RM. The radiation response of human malignant melanoma cells grown in vitro. Cancer Res. 1971; 31:830-833.
    • (1971) Cancer Res. , vol.31 , pp. 830-833
    • Barranco, S.C.1    Romsdahl, M.M.2    Humphrey, R.M.3
  • 31
    • 79952264449 scopus 로고    scopus 로고
    • Outcome predictors of gamma knife surgery for melanoma brain metastases. Clinical article
    • Liew DN, Kano H, Kondziolka D, et al. Outcome predictors of gamma knife surgery for melanoma brain metastases. Clinical article. J Neurosurg. 2011;114:769-779.
    • (2011) J Neurosurg. , vol.114 , pp. 769-779
    • Liew, D.N.1    Kano, H.2    Kondziolka, D.3
  • 32
    • 33644850757 scopus 로고    scopus 로고
    • Whole-brain radiotherapy in the management of brain metastasis
    • DOI 10.1200/JCO.2005.04.6185
    • Khuntia D, Brown P, Li J, et al. Whole-brain radiotherapy in the management of brain metastasis. J Clin Oncol. 2006;24:1295-1304. (Pubitemid 46622033)
    • (2006) Journal of Clinical Oncology , vol.24 , Issue.8 , pp. 1295-1304
    • Khuntia, D.1    Brown, P.2    Li, J.3    Mehta, M.P.4
  • 33
    • 0018868258 scopus 로고
    • Value of radiation therapy in the management of patients with cerebral metastases from malignant melanoma. Radiation Therapy Oncology Group Brain Metastases Study I and II
    • DOI 10.1002/1097-0142(19800215)45:4<679::AID-CNCR2820450410>3.0. CO;2-J
    • Carella RJ, Gelber R, Hendrickson F, et al. Value of radiation therapy in the management of patients with cerebral metastases from malignant melanoma: Radiation Therapy Oncology Group Brain Metastases Study I and II. Cancer. 1980;45:679-683. (Pubitemid 10174607)
    • (1980) Cancer , vol.45 , Issue.4 , pp. 679-683
    • Carella, R.J.1    Gelber, R.2    Hendrickson, F.3
  • 36
    • 79951966253 scopus 로고    scopus 로고
    • Adjuvant whole-brain radiotherapy versus observation after radiosurgery or surgical resection of one to three cerebral metastases: Results of the EORTC 22952-26001 study
    • Kocher M, Soffietti R, Abacioglu U, et al. Adjuvant whole-brain radiotherapy versus observation after radiosurgery or surgical resection of one to three cerebral metastases: results of the EORTC 22952-26001 study. J Clin Oncol. 2011;29:134-141.
    • (2011) J Clin Oncol. , vol.29 , pp. 134-141
    • Kocher, M.1    Soffietti, R.2    Abacioglu, U.3
  • 37
    • 71249157772 scopus 로고    scopus 로고
    • Neurocognition in patients with brain metastases treated with radiosurgery or radiosurgery plus whole-brain irradiation: A randomised controlled trial
    • Chang EL, Wefel JS, Hess KR, et al. Neurocognition in patients with brain metastases treated with radiosurgery or radiosurgery plus whole-brain irradiation: a randomised controlled trial. Lancet Oncol. 2009; 10:1037-1044.
    • (2009) Lancet Oncol. , vol.10 , pp. 1037-1044
    • Chang, E.L.1    Wefel, J.S.2    Hess, K.R.3
  • 38
    • 79957967246 scopus 로고    scopus 로고
    • Whole brain radiotherapy after local treatment of brain metastases in melanoma patientsVa randomised phase III trial
    • Fogarty G, Morton R, Vardy J, et al. Whole brain radiotherapy after local treatment of brain metastases in melanoma patientsVa randomised phase III trial. BMC Cancer. 2011;11:142.
    • (2011) BMC Cancer. , vol.11 , pp. 142
    • Fogarty, G.1    Morton, R.2    Vardy, J.3
  • 39
    • 77954801079 scopus 로고    scopus 로고
    • Improved survival with ipilimumab in patients with metastatic melanoma
    • Hodi FS, O'Day SJ, McDermott DF, et al. Improved survival with ipilimumab in patients with metastatic melanoma. N Engl J Med. 2010;363:711-723.
    • (2010) N Engl J Med. , vol.363 , pp. 711-723
    • Hodi, F.S.1    O'Day, S.J.2    McDermott, D.F.3
  • 40
    • 79959772576 scopus 로고    scopus 로고
    • Ipilimumab plus dacarbazine for previously untreated metastatic melanoma
    • Robert C, Thomas L, Bondarenko I, et al. Ipilimumab plus dacarbazine for previously untreated metastatic melanoma. N Engl J Med. 2011; 364:2517-2526.
    • (2011) N Engl J Med. , vol.364 , pp. 2517-2526
    • Robert, C.1    Thomas, L.2    Bondarenko, I.3
  • 41
    • 79959795786 scopus 로고    scopus 로고
    • Improved survival with vemurafenib in melanoma with BRAF V600E mutation
    • Chapman PB, Hauschild A, Robert C, et al. Improved survival with vemurafenib in melanoma with BRAF V600E mutation. N Engl J Med. 2011;364:2507-2516.
    • (2011) N Engl J Med. , vol.364 , pp. 2507-2516
    • Chapman, P.B.1    Hauschild, A.2    Robert, C.3
  • 43
    • 0003280739 scopus 로고    scopus 로고
    • Cerebrospinal fluid levels of temozolomide as a surrogate marker for brain penetration
    • Stupp R, Ostermann S, Leyvraz S, et al. Cerebrospinal fluid levels of temozolomide as a surrogate marker for brain penetration. Proc Am Soc Clin Oncol. 2001;20: Abstract 232.
    • (2001) Proc Am Soc Clin Oncol. , vol.20 , pp. 232
    • Stupp, R.1    Ostermann, S.2    Leyvraz, S.3
  • 48
    • 0036208833 scopus 로고    scopus 로고
    • Temozolomide and whole brain irradiation in melanoma metastatic to the brain: A phase II trial of the Cytokine Working Group
    • Margolin, Atkins, Thompson, et al. Temozolomide and whole brain irradiation in melanoma metastatic to the brain: a phase II trial of the Cytokine Working Group. J Cancer Res Clin Oncol. 2002;128:214-218.
    • (2002) J Cancer Res Clin Oncol. , vol.128 , pp. 214-218
    • Atkins Thompson, M.1
  • 50
    • 77957587190 scopus 로고    scopus 로고
    • Phase II trial of ipilim-umab monotherapy in melanoma patients with brain metastases
    • Lawrence DP, Hamid O, McDermott DF, et al. Phase II trial of ipilim-umab monotherapy in melanoma patients with brain metastases. J Clin Oncol. 2010;28: Abstract 8523.
    • (2010) J Clin Oncol. , vol.28 , pp. 8523
    • Lawrence, D.P.1    Hamid, O.2    McDermott, D.F.3
  • 51
    • 84858440498 scopus 로고    scopus 로고
    • Ipilimumab improves survival in previously treated, advanced melanoma patients with poor prognostic factors: Subgroup analysis from a phase III trial
    • Lebbé C, McDermott D, Robert C, et al. Ipilimumab improves survival in previously treated, advanced melanoma patients with poor prognostic factors: subgroup analysis from a phase III trial. Ann Oncol. 2010; Abstract 13240.
    • Ann Oncol. , vol.2010 , pp. 13240
    • Lebbé, C.1    McDermott, D.2    Robert, C.3
  • 54
    • 55949125601 scopus 로고    scopus 로고
    • Adoptive cell therapy for patients with metastatic melanoma: Evaluation of intensive myeloablative che-moradiation preparative regimens
    • Dudley ME, Yang JC, Sherry R, et al. Adoptive cell therapy for patients with metastatic melanoma: evaluation of intensive myeloablative che-moradiation preparative regimens. J Clin Oncol. 2008;26:5233-5239.
    • (2008) J Clin Oncol. , vol.26 , pp. 5233-5239
    • Dudley, M.E.1    Yang, J.C.2    Sherry, R.3
  • 55
    • 77957606517 scopus 로고    scopus 로고
    • Successful treatment of melanoma brain metastases with adoptive cell therapy
    • Hong JJ, Rosenberg SA, Dudley ME, et al. Successful treatment of melanoma brain metastases with adoptive cell therapy. Clin Cancer Res. 2010;16:4892-4898.
    • (2010) Clin Cancer Res. , vol.16 , pp. 4892-4898
    • Hong, J.J.1    Rosenberg, S.A.2    Dudley, M.E.3
  • 56
    • 79953891558 scopus 로고    scopus 로고
    • Phase 1/2 study of GSK2118436, a selective inhibitor of V600 mutant (Mut) BRAF kinase: Evidence of activity in melanoma brain metastases (Mets)
    • Long GV, Kefford RF, Carr PJA, et al. Phase 1/2 study of GSK2118436, a selective inhibitor of V600 mutant (Mut) BRAF kinase: evidence of activity in melanoma brain metastases (Mets). Ann Oncol. 2010: Abstract LBA 27.
    • (2010) Ann Oncol. , pp. 27
    • Long, G.V.1    Kefford, R.F.2    Carr, P.J.A.3
  • 57
    • 84858752302 scopus 로고    scopus 로고
    • An open-label pilot study of vemurafenib in previously treated metastatic melanoma patients with brain metastases
    • Dummer R, Rinderknecht J, Goldinger SM, et al. An open-label pilot study of vemurafenib in previously treated metastatic melanoma patients with brain metastases. J Clin Oncol. 2011;29[suppl]: Abstract 8548.
    • (2011) J Clin Oncol. , vol.29 , Issue.SUPPL. , pp. 8548
    • Dummer, R.1    Rinderknecht, J.2    Goldinger, S.M.3


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