Pharmacokinetics of aconitine in rat skin after oral and transdermal gel administrations

Biomedical Chromatography

Volumn 26, Issue 5, 2012, Pages 622-626

  Zhang, Quan Long ^a   Hu, Jin Hong ^b   Jia, Zheng Ping ^a   Wang, Dan ^c   Zhu, Quan Gang ^b  

^a LANZHOU GENERAL HOSPITAL   (China)

^b SECOND MILITARY MEDICAL UNIVERSITY   (China)

^c General Hospital of the Second Artillery   (China)

Author keywords

Aconitine; Arrhythmia; Microdialysis; Pharmacokinetic; Transdermal

Indexed keywords

DIALYSIS; ELECTROCARDIOGRAMS; RATS;

ACONITINE; ARRHYTHMIA; IN-VIVO; MICRO-DIALYSIS; ORAL ADMINISTRATION; ORAL ROUTE; PERCUTANEOUS PENETRATION; RAT SKIN; TRANSDERMAL; TRANSDERMAL ADMINISTRATION;

PHARMACOKINETICS;

ACONITINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG HALF LIFE; DRUG PENETRATION; DRUG TISSUE LEVEL; ELECTROCARDIOGRAM; HEART ARRHYTHMIA; HEART VENTRICLE FIBRILLATION; HEART VENTRICLE TACHYCARDIA; IN VIVO STUDY; MALE; MAXIMUM PLASMA CONCENTRATION; MICRODIALYSIS; NONHUMAN; RAT; TIME TO MAXIMUM PLASMA CONCENTRATION;

RATTUS;

EID: 84859445848     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.1707     Document Type: Article

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