Identification, characterization and cytotoxicity in vitro assay of nitazoxanide major degradation product

Talanta

Volumn 93, Issue , 2012, Pages 206-211

  Malesuik, Marcelo Donadel ^a   Gonalves, Heloísa Mazotti Lopes ^a   Garcia, Cássia Virginia ^a   Trein, Márcia Rodrigues ^a   Nardi, Nance Beyer ^a   Schapoval, Elfrides Eva Scherman ^a   Steppe, Martin ^a  

^a FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

Author keywords

Cytotoxicity in vitro assay; Degradation product; Nitazoxanide; Stress degradation

Indexed keywords

CYTOTOXICITY; DRUG PRODUCTS;

BROAD SPECTRUM; CYTOTOXICITY IN VITRO; DEGRADATION PRODUCTS; MONONUCLEAR CELLS; NITAZOXANIDE; PHARMACEUTICAL DRUGS; PHOTOLYTIC DECOMPOSITION; STRESS DEGRADATION;

DEGRADATION;

EID: 84859429198     PISSN: 00399140     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.talanta.2012.02.014     Document Type: Article

References (20)

1. W. Raether, and H. Hänel Parasitol. Res. 90 2003 S19 S39
2. L.M. Fox, and L.D. Saravolatz Clin. Infect. Dis. 40 2005 1173 1180
3. A. Stockis, X. Deroubaix, R. Lins, B. Jeanbaptiste, P. Calderon, and J.F. Rossignol Int. J. Clin. Pharmacol. Ther. 34 1996 349 351
4. J. Broekhuysen, A. Stockis, R.L. Lins, J. De Graeve, and J.F. Rossignol Int. J. Clin. Pharmacol. Ther. 38 2000 387 394
5. Z. Zhao, L. Zhang, F. Xue, X. Wang, W. Zheng, T. Zhang, C. Fei, K. Zhang, M. Qiu, R. Xin, and F. Yang J. Chromatogr. B 875 2008 427 436
6. G.K. Kapse, G. Prabhakar, and S.A. Raju Indian J. Pharm. Sci. 68 2006 403 406
7. C.L. Gopu, S. Thomas, A.R. Paradkar, and K.R. Mahadik J. Sci. Ind. Res. 66 2007 141 145
8. A.S. Jadhav, D.B. Pathare, and M.S. Shingare Chromatographia 66 2007 595 600
9. M.D. Malesuik, S.G. Cardoso, and M. Steppe Chromatographia 67 2008 131 136
10. V.P. Rane, J.N. Sangshetti, K.R. Patil, R.D. Yeole, and D.B. Shinde Chromatographia 67 2008 455 459
11. A.R. Breier, N.S. Nudelman, M. Steppe, and E.E.S. Schapoval J. Pharm. Biomed. Anal. 46 2008 250 257
12. A. Mendez, P. Chagastelles, E. Palma, N. Nardi, and E.E.S. Schapoval Int. J. Pharm. 350 2008 95 102
13. C.V. Garcia, N.S. Nudelman, M. Steppe, and E.E.S. Schapoval J. Pharm. Biomed. Anal. 46 2008 88 93
14. M.S. Sangoi, V. Todeschini, and M. Steppe Talanta 84 2011 1068 1079
15. N.S. Nudelman, El Ateneo (Eds.), Estabilidad de Medicamentos, Buenos Aires, 1975, pp. 45-94.
16. B. Kommanaboyina, and C.T. Rhodes Drug Dev. Ind. Pharm. 25 1999 857 868
17. ICH International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use Stability Testing of New Drug Substances and Products Q1A(R2) 2003 ICH Steering Committee Switzerland
18. M.D. Malesuik, H.M.L. Gonalves, C.S. Paim, E.E.S. Schapoval, and M. Steppe J. Chromatogr. Sci. 47 2009 745 748
19. ICH International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use Impurities in New Drug Products Q3A(R2) 2006 ICH Steering Committee Switzerland
20. Z. Zhao, L. Zhang, F. Xue, and T. Zhang Chromatographia 68 2008 731 738