메뉴 건너뛰기




Volumn 347, Issue 3, 2012, Pages 701-711

Scaffold-free culture of mesenchymal stem cell spheroids in suspension preserves multilineage potential

Author keywords

Mesenchymal stem cell; Scaffold free culture; Suspension culture; Tissue engineering

Indexed keywords

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL DEATH; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL SIZE; CELL STRUCTURE; CELL SUSPENSION; CELL VACUOLE; CONTROLLED STUDY; CULTURE MEDIUM; EXTRACELLULAR MATRIX; MESENCHYMAL STEM CELL; MINERALIZATION; MONOLAYER CULTURE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SPHEROID CELL; TISSUE CULTURE;

EID: 84859427951     PISSN: 0302766X     EISSN: 14320878     Source Type: Journal    
DOI: 10.1007/s00441-011-1215-5     Document Type: Article
Times cited : (207)

References (37)
  • 2
    • 84934443078 scopus 로고    scopus 로고
    • Mesenchymal stem cells from adult bone marrow
    • Pittenger MF (2008) Mesenchymal stem cells from adult bone marrow. Methods Mol Biol 449:27-44
    • (2008) Methods Mol Biol , vol.449 , pp. 27-44
    • Pittenger, M.F.1
  • 4
    • 77649285139 scopus 로고    scopus 로고
    • Stem cell paracrine actions and tissue regeneration
    • Baraniak PR, McDevitt TC (2010) Stem cell paracrine actions and tissue regeneration. Regen Med 5(1):121-143
    • (2010) Regen Med , vol.5 , Issue.1 , pp. 121-143
    • Baraniak, P.R.1    McDevitt, T.C.2
  • 6
    • 76249107254 scopus 로고    scopus 로고
    • DNAmethylation pattern changes upon long-term culture and aging of human mesenchymal stromal cells
    • Bork S, Pfister S, Witt H, Horn P, Korn B, Ho AD, Wagner W (2010) DNAmethylation pattern changes upon long-term culture and aging of human mesenchymal stromal cells. Aging Cell 9(1):54-63
    • (2010) Aging Cell , vol.9 , Issue.1 , pp. 54-63
    • Bork, S.1    Pfister, S.2    Witt, H.3    Horn, P.4    Korn, B.5    Ho, A.D.6    Wagner, W.7
  • 7
    • 33646039757 scopus 로고    scopus 로고
    • Glucose-induced replicative senescence in mesenchymal stem cells
    • Stolzing A, Coleman N, Scutt A (2006) Glucose-induced replicative senescence in mesenchymal stem cells. Rejuvenation Res 9 (1):31-35
    • (2006) Rejuvenation Res , vol.9 , Issue.1 , pp. 31-35
    • Stolzing, A.1    Coleman, N.2    Scutt, A.3
  • 9
    • 33751572020 scopus 로고    scopus 로고
    • Rapid generation of single-tumor spheroids for high-throughput cell function and toxicity analysis
    • DOI 10.1177/1087057106292763
    • Ivascu A, Kubbies M (2006) Rapid generation of single-tumor spheroids for high-throughput cell function and toxicity analysis. J Biomol Screen 11(8):922-932 (Pubitemid 44847146)
    • (2006) Journal of Biomolecular Screening , vol.11 , Issue.8 , pp. 922-932
    • Ivascu, A.1    Kubbies, M.2
  • 10
    • 70349306322 scopus 로고    scopus 로고
    • Generation of a tumor spheroid in a microgravity environment as a 3D model of melanoma
    • Marrero B, Messina JL, Heller R (2009) Generation of a tumor spheroid in a microgravity environment as a 3D model of melanoma. In Vitro Cell Dev Biol Anim 45(9):523-534
    • (2009) In Vitro Cell Dev Biol Anim , vol.45 , Issue.9 , pp. 523-534
    • Marrero, B.1    Messina, J.L.2    Heller, R.3
  • 12
    • 38449089459 scopus 로고    scopus 로고
    • Generation of multicellular tumor spheroids by the hanging-drop method
    • Timmins NE, Nielsen LK (2007) Generation of multicellular tumor spheroids by the hanging-drop method. Methods Mol Med 140:141-151
    • (2007) Methods Mol Med , vol.140 , pp. 141-151
    • Timmins, N.E.1    Nielsen, L.K.2
  • 13
    • 34250860104 scopus 로고    scopus 로고
    • Methods for inducing embryoid body formation: In vitro differentiation system of embryonic stem cells
    • Kurosawa H (2007) Methods for inducing embryoid body formation: in vitro differentiation system of embryonic stem cells. J Biosci Bioeng 103(5):389-398
    • (2007) J Biosci Bioeng , vol.103 , Issue.5 , pp. 389-398
    • Kurosawa, H.1
  • 15
    • 60849103067 scopus 로고    scopus 로고
    • Homogeneous and organized differentiation within embryoid bodies induced by microsphere-mediated delivery of small molecules
    • Carpenedo RL, Bratt-Leal AM, Marklein RA, Seaman SA, Bowen NJ, McDonald JF, McDevitt TC (2009) Homogeneous and organized differentiation within embryoid bodies induced by microsphere-mediated delivery of small molecules. Biomaterials 30(13):2507-2515
    • (2009) Biomaterials , vol.30 , Issue.13 , pp. 2507-2515
    • Carpenedo, R.L.1    Bratt-Leal, A.M.2    Marklein, R.A.3    Seaman, S.A.4    Bowen, N.J.5    McDonald, J.F.6    McDevitt, T.C.7
  • 16
    • 72249083521 scopus 로고    scopus 로고
    • A novel three-dimensional culture system for isolation and clonal propagation of neural stem cells using a thermo-reversible gelation polymer
    • Yang XZ, Kataoka K, Medina R, Yamamoto K, Than SS, Miyazaki M, Huh NH (2009) A novel three-dimensional culture system for isolation and clonal propagation of neural stem cells using a thermo-reversible gelation polymer. Tissue Eng Part C Methods 15(4):615-623
    • (2009) Tissue Eng Part C Methods , vol.15 , Issue.4 , pp. 615-623
    • Yang, X.Z.1    Kataoka, K.2    Medina, R.3    Yamamoto, K.4    Than, S.S.5    Miyazaki, M.6    Huh, N.H.7
  • 17
    • 77955158299 scopus 로고    scopus 로고
    • The utility and limitations of neurosphere assay, CD133 immunophenotyping and side population assay in glioma stem cell research
    • Wan F, Zhang S, Xie R, Gao B, Campos B, Herold-Mende C, Lei T (2010) The utility and limitations of neurosphere assay, CD133 immunophenotyping and side population assay in glioma stem cell research. Brain Pathol 20(5):877-889
    • (2010) Brain Pathol , vol.20 , Issue.5 , pp. 877-889
    • Wan, F.1    Zhang, S.2    Xie, R.3    Gao, B.4    Campos, B.5    Herold-Mende, C.6    Lei, T.7
  • 18
    • 77953013554 scopus 로고    scopus 로고
    • Isolation and generation of neurosphere cultures from embryonic and adult mouse brain
    • Ahlenius H, Kokaia Z (2010) Isolation and generation of neurosphere cultures from embryonic and adult mouse brain. Methods Mol Biol 633:241-252
    • (2010) Methods Mol Biol , vol.633 , pp. 241-252
    • Ahlenius, H.1    Kokaia, Z.2
  • 21
    • 33750953664 scopus 로고    scopus 로고
    • Design of custom-shaped vascularized tissues using microtissue spheroids as minimal building units
    • DOI 10.1089/ten.2006.12.2151
    • Kelm JM, Djonov V, Ittner LM, Fluri D, Born W, Hoerstrup SP, Fussenegger M (2006) Design of custom-shaped vascularized tissues using microtissue spheroids as minimal building units. Tissue Eng 12(8):2151-2160 (Pubitemid 44734974)
    • (2006) Tissue Engineering , vol.12 , Issue.8 , pp. 2151-2160
    • Kelm, J.M.1    Djonov, V.2    Ittner, L.M.3    Fluri, D.4    Born, W.5    Hoerstrup, S.P.6    Fussenegger, M.7
  • 23
    • 1442332442 scopus 로고    scopus 로고
    • Adult stem cells from bone marrow (MSCs) isolated from different strains of inbred mice vary in surface epitopes, rates of proliferation, and differentiation potential
    • DOI 10.1182/blood-2003-09-3070
    • Peister A, Mellad JA, Larson BL, Hall BM, Gibson LF, Prockop DJ (2004) Adult stem cells from bone marrow (MSCs) isolated from different strains of inbred mice vary in surface epitopes, rates of proliferation, and differentiation potential. Blood 103(5):1662-1668 (Pubitemid 38268957)
    • (2004) Blood , vol.103 , Issue.5 , pp. 1662-1668
    • Peister, A.1    Mellad, J.A.2    Larson, B.L.3    Hall, B.M.4    Gibson, L.F.5    Prockop, D.J.6
  • 24
    • 45349084219 scopus 로고    scopus 로고
    • Reproducible, ultra high-throughput formation of multicellular organization from single cell suspension-derived human embryonic stem cell aggregates
    • Ungrin MD, Joshi C, Nica A, Bauwens C, Zandstra PW (2008) Reproducible, ultra high-throughput formation of multicellular organization from single cell suspension-derived human embryonic stem cell aggregates. PLoS One 3(2):e1565
    • (2008) PLoS One , vol.3 , Issue.2
    • Ungrin, M.D.1    Joshi, C.2    Nica, A.3    Bauwens, C.4    Zandstra, P.W.5
  • 25
    • 34748921666 scopus 로고    scopus 로고
    • Rotary suspension culture enhances the efficiency, yield, and homogeneity of embryoid body differentiation
    • Carpenedo RL, Sargent CY, McDevitt TC (2007) Rotary suspension culture enhances the efficiency, yield, and homogeneity of embryoid body differentiation. Stem Cell 25(9):2224-2234
    • (2007) Stem Cell , vol.25 , Issue.9 , pp. 2224-2234
    • Carpenedo, R.L.1    Sargent, C.Y.2    McDevitt, T.C.3
  • 27
    • 2342559147 scopus 로고    scopus 로고
    • An Alizarin red-based assay of mineralization by adherent cells in culture: Comparison with cetylpyridinium chloride extraction
    • DOI 10.1016/j.ab.2004.02.002, PII S0003269704001332
    • Gregory CA, Gunn WG, Peister A, Prockop DJ (2004) An Alizarin red-based assay of mineralization by adherent cells in culture: comparison with cetylpyridinium chloride extraction. Anal Biochem 329(1):77-84 (Pubitemid 38596903)
    • (2004) Analytical Biochemistry , vol.329 , Issue.1 , pp. 77-84
    • Gregory, C.A.1    Gunn, W.G.2    Peister, A.3    Prockop, D.J.4
  • 29
    • 21744438592 scopus 로고    scopus 로고
    • Mesenchymal stem cells from the outer ear: A novel adult stem cell model system for the study of adipogenesis
    • DOI 10.1096/fj.04-3204fje
    • Rim JS, Mynatt RL, Gawronska-Kozak B (2005) Mesenchymal stem cells from the outer ear: a novel adult stem cell model system for the study of adipogenesis. FASEB J 19(9):1205-1207 (Pubitemid 40946466)
    • (2005) FASEB Journal , vol.19 , Issue.9 , pp. 1205-1207
    • Rim, J.-S.1    Mynatt, R.L.2    Gawronska-Kozak, B.3
  • 30
    • 77957373160 scopus 로고    scopus 로고
    • Microcapsules Embedded with Three-Dimensional Fibrous Scaffolds for Cell Culture and Tissue Engineering
    • in press
    • Huang X, Wang J, Xie H, Zhang Y, Wang W, Yu W, Liu Y, and Ma X (2010) Microcapsules Embedded with Three-Dimensional Fibrous Scaffolds for Cell Culture and Tissue Engineering. Tissue Eng Part C Methods (in press)
    • (2010) Tissue Eng Part C Methods
    • Huang, X.1    Wang, J.2    Xie, H.3    Zhang, Y.4    Wang, W.5    Yu, W.6    Liu, Y.7    Ma, X.8
  • 31
    • 41649093599 scopus 로고    scopus 로고
    • Defining the role of matrix compliance and proteolysis in three-dimensional cell spreading and remodeling
    • Dikovsky D, Bianco-Peled H, Seliktar D (2008) Defining the role of matrix compliance and proteolysis in three-dimensional cell spreading and remodeling. Biophys J 94(7):2914-2925
    • (2008) Biophys J , vol.94 , Issue.7 , pp. 2914-2925
    • Dikovsky, D.1    Bianco-Peled, H.2    Seliktar, D.3
  • 32
    • 33644788812 scopus 로고    scopus 로고
    • Increased cell compaction can augment the resistance of HT-29 human colon adenocarcinoma spheroids to ionizing radiation
    • Ferrante A, Rainaldi G, Indovina P, Indovina PL, Santini MT (2006) Increased cell compaction can augment the resistance of HT-29 human colon adenocarcinoma spheroids to ionizing radiation. Int J Oncol 28(1):111-118
    • (2006) Int J Oncol , vol.28 , Issue.1 , pp. 111-118
    • Ferrante, A.1    Rainaldi, G.2    Indovina, P.3    Indovina, P.L.4    Santini, M.T.5
  • 33
    • 33646368912 scopus 로고    scopus 로고
    • Dynamic analysis of hepatoma spheroid formation: Roles of E-cadherin and beta1- Integrin
    • Lin RZ, Chou LF, Chien CC, Chang HY (2006) Dynamic analysis of hepatoma spheroid formation: roles of E-cadherin and beta1- integrin. Cell Tissue Res 324(3):411-422
    • (2006) Cell Tissue Res , vol.324 , Issue.3 , pp. 411-422
    • Lin, R.Z.1    Chou, L.F.2    Chien, C.C.3    Chang, H.Y.4
  • 34
    • 1542373992 scopus 로고    scopus 로고
    • Fibronectin Matrix Assembly Regulates alpha5beta1-mediated Cell Cohesion
    • DOI 10.1091/mbc.E03-07-0528
    • Robinson EE, Foty RA, Corbett SA (2004) Fibronectin matrix assembly regulates alpha5beta1-mediated cell cohesion. Mol Biol Cell 15(3):973-981 (Pubitemid 38316208)
    • (2004) Molecular Biology of the Cell , vol.15 , Issue.3 , pp. 973-981
    • Robinson, E.E.1    Foty, R.A.2    Corbett, S.A.3
  • 35
    • 77955000681 scopus 로고    scopus 로고
    • Dynamic three-dimensional culture methods enhance mesenchymal stem cell properties and increase therapeutic potential
    • Translated from eng
    • Frith JE, Thomson B, Genever PG (2010) Dynamic three-dimensional culture methods enhance mesenchymal stem cell properties and increase therapeutic potential. (Translated from eng). Tissue Eng Part C Methods 16(4):735-749
    • (2010) Tissue Eng Part C Methods , vol.16 , Issue.4 , pp. 735-749
    • Frith, J.E.1    Thomson, B.2    Genever, P.G.3
  • 36
    • 0035480032 scopus 로고    scopus 로고
    • Anoikis mechanisms
    • Translated from eng
    • Frisch SM, Screaton RA (2001) Anoikis mechanisms. (Translated from eng). Curr Opin Cell Biol 13(5):555-562
    • (2001) Curr Opin Cell Biol , vol.13 , Issue.5 , pp. 555-562
    • Frisch, S.M.1    Screaton, R.A.2
  • 37
    • 77953827366 scopus 로고    scopus 로고
    • Microsphere size effects on embryoid body incorporation and embryonic stem cell differentiation
    • Carpenedo RL, Seaman SA, McDevitt TC (2010) Microsphere size effects on embryoid body incorporation and embryonic stem cell differentiation. J Biomed Mater Res Part A 94(2):466-475
    • (2010) J Biomed Mater Res Part A , vol.94 , Issue.2 , pp. 466-475
    • Carpenedo, R.L.1    Seaman, S.A.2    McDevitt, T.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.