-
1
-
-
0029913882
-
Defining the clinical course of multiple sclerosis: Results of an international survey
-
Lublin FD, Reingold SC. Defining the clinical course of multiple sclerosis: results of an international survey. Neurology. 1996;46:907-911.
-
(1996)
Neurology.
, vol.46
, pp. 907-911
-
-
Lublin, F.D.1
Reingold, S.C.2
-
2
-
-
39749200152
-
Disability and T2 MRI lesions: A 20-year follow-up of patients with relapse onset multiple sclerosis
-
Fisniku LK, Brex PA, Altmann DR et al. Disability and T2 MRI lesions: a 20-year follow-up of patients with relapse onset multiple sclerosis. Brain. 2008;131:808-817.
-
(2008)
Brain.
, vol.131
, pp. 808-817
-
-
Fisniku, L.K.1
Brex, P.A.2
Altmann, D.R.3
-
4
-
-
0032994147
-
The immunobiology of multiple sclerosis: An autoimmune disease of the central nervous system
-
Conlon P, Oksenberg JR, Zhang J. The immunobiology of multiple sclerosis: an autoimmune disease of the central nervous system. Neurobiol Dis. 1999;6:149-166.
-
(1999)
Neurobiol Dis.
, vol.6
, pp. 149-166
-
-
Conlon, P.1
Oksenberg, J.R.2
Zhang, J.3
-
5
-
-
0035554905
-
Immunotherapy of multiple sclerosis: Where are we? Where should we go?
-
Martin R, Stürzebecher CS, McFarland HF. Immunotherapy of multiple sclerosis: Where are we? Where should we go? Nature Immunol. 2001;2:785-788.
-
(2001)
Nature Immunol.
, vol.2
, pp. 785-788
-
-
Martin, R.1
Stürzebecher, C.S.2
McFarland, H.F.3
-
6
-
-
0008376732
-
Interferon beta in the treatment of multiple sclerosis: Mechanisms of action
-
Yong VW, Chabot S, Stüve O, et al. Interferon beta in the treatment of multiple sclerosis: mechanisms of action. Neurology. 1998;51:692-689.
-
(1998)
Neurology.
, vol.51
, pp. 689-692
-
-
Yong, V.W.1
Chabot, S.2
Stüve, O.3
-
7
-
-
0027366326
-
Interferon ββdecreases T-cell activation and interferon γγproduction in multiple sclerosis
-
Noronha A, Toscas A, Jensen MA. Interferon ββdecreases T-cell activation and interferon γγproduction in multiple sclerosis. J Neuroimmunol. 1993;46:145-154.
-
(1993)
J Neuroimmunol.
, vol.46
, pp. 145-154
-
-
Noronha, A.1
Toscas, A.2
Jensen, M.A.3
-
8
-
-
0037161237
-
Mechanisms of action of interferons and glatiramer acetate in multiple sclerosis
-
Dhib-Jalbut S. Mechanisms of action of interferons and glatiramer acetate in multiple sclerosis. Neurology. 2002;58:S3-S9.
-
(2002)
Neurology.
, vol.58
-
-
Dhib-Jalbut, S.1
-
9
-
-
33947681258
-
Cytokine changes during interferonbeta therapy in multiple sclerosis: Correlations with interferon dose and MRI response
-
Graber JJ, Ford D, Zhan M, et al. Cytokine changes during interferonbeta therapy in multiple sclerosis: correlations with interferon dose and MRI response. J Neuroimmunol. 2007;185:168-174.
-
(2007)
J Neuroimmunol.
, vol.185
, pp. 168-174
-
-
Graber, J.J.1
Ford, D.2
Zhan, M.3
-
10
-
-
0030498666
-
Interferon β-1b decreases the migration of T lymphocytes in vitro: Effects on matrix metalloproteinase-9
-
Stüve O, Dooley NP, Uhm JH, et al. Interferon β-1b decreases the migration of T lymphocytes in vitro: effects on matrix metalloproteinase-9. Ann Neurol. 1996;40:853-863.
-
(1996)
Ann Neurol.
, vol.40
, pp. 853-863
-
-
Stüve, O.1
Dooley, N.P.2
Uhm, J.H.3
-
11
-
-
0030483220
-
Interferon beta-1b inhibits gelatinase secretion and in vitro migration of human T cells: A possible mechanism for treatment efficacy in multiple sclerosis
-
Leppert D, Waubant E, Bürk MR, et al. Interferon beta-1b inhibits gelatinase secretion and in vitro migration of human T cells: a possible mechanism for treatment efficacy in multiple sclerosis. Ann Neurol. 1996;40:846-852.
-
(1996)
Ann Neurol.
, vol.40
, pp. 846-852
-
-
Leppert, D.1
Waubant, E.2
Bürk, M.R.3
-
12
-
-
0028988737
-
The effect of interferon-ββon blood-brain barrier disruptions demonstrated by contrast-enhanced magnetic resonance imaging in relapsing-remitting multiple sclerosis
-
Stone LA, Frank JA, Albert PS, et al. The effect of interferon-ββon blood-brain barrier disruptions demonstrated by contrast-enhanced magnetic resonance imaging in relapsing-remitting multiple sclerosis. Ann Neurol. 1995;37:611-619.
-
(1995)
Ann Neurol.
, vol.37
, pp. 611-619
-
-
Stone, L.A.1
Frank, J.A.2
Albert, P.S.3
-
13
-
-
3843101531
-
Interferon-ββstabilizes barrier characteristics for brain endothelial cells in vitro
-
Kraus J, Ling AK, Hamm S, et al. Interferon-ββstabilizes barrier characteristics for brain endothelial cells in vitro. Ann Neurol. 2004;56:192-205.
-
(2004)
Ann Neurol.
, vol.56
, pp. 192-205
-
-
Kraus, J.1
Ling, A.K.2
Hamm, S.3
-
14
-
-
0030610524
-
Increases in soluble VCAM-1 correlate with a decrease in MRI lesions in multiple sclerosis treated with interferon beta-1b
-
Calabresi PA, Tranquill LR, Dambrosia JM, et al. Increases in soluble VCAM-1 correlate with a decrease in MRI lesions in multiple sclerosis treated with interferon beta-1b. Ann Neurol. 1997;41: 669-674.
-
(1997)
Ann Neurol.
, vol.41
, pp. 669-674
-
-
Calabresi, P.A.1
Tranquill, L.R.2
Dambrosia, J.M.3
-
15
-
-
14844297366
-
Interferonβ-1a induces increases in vascular cell adhesion molecule: Implications for its mode of action in multiple sclerosis
-
Graber J, Zhan M, Ford D, et al. Interferonβ-1a induces increases in vascular cell adhesion molecule: implications for its mode of action in multiple sclerosis. J Neuroimmunol. 2005;161:169-176.
-
(2005)
J Neuroimmunol.
, vol.161
, pp. 169-176
-
-
Graber, J.1
Zhan, M.2
Ford, D.3
-
16
-
-
0037167526
-
Differential mechanisms of action of interferon-ββand glatiramer acetate in MS
-
Yong VW. Differential mechanisms of action of interferon-ββand glatiramer acetate in MS. Neurology. 2002;59:802-808.
-
(2002)
Neurology.
, vol.59
, pp. 802-808
-
-
Yong, V.W.1
-
17
-
-
84900541932
-
Interferon-beta therapy down regulates the anti-apoptosis protein FLIP in T cells from patients with multiple sclerosis
-
Sharief MK, Semra YK, Seidi OA, et al. Interferon-beta therapy down regulates the anti-apoptosis protein FLIP in T cells from patients with multiple sclerosis. J Neuroimmunol. 2001;121:102-110.
-
(2001)
J Neuroimmunol.
, vol.121
, pp. 102-110
-
-
Sharief, M.K.1
Semra, Y.K.2
Seidi, O.A.3
-
18
-
-
34249021938
-
Interferon-ββregulates cytokines and BDNF: Greater effect in relapsing than in progressive multiple sclerosis
-
Hamamcioglu K, Reder AT. Interferon-ββregulates cytokines and BDNF: greater effect in relapsing than in progressive multiple sclerosis. Mult Scler. 2007;13:459-470.
-
(2007)
Mult Scler.
, vol.13
, pp. 459-470
-
-
Hamamcioglu, K.1
Reder, A.T.2
-
19
-
-
16844385713
-
Interferon beta promotes nerve growth factor secretion early in the course of multiple sclerosis
-
Biernacki K, Antel AP, Blain M et al. Interferon beta promotes nerve growth factor secretion early in the course of multiple sclerosis. Arch Neurol. 2005;62:563-568.
-
(2005)
Arch Neurol.
, vol.62
, pp. 563-568
-
-
Biernacki, K.1
Antel, A.P.2
Blain, M.3
-
20
-
-
0030112474
-
Interferon-ββeffects on cytokine mRNA in peripheral mononuclear cells in multiple sclerosis
-
Byskosh PV, Reder AT. Interferon-ββeffects on cytokine mRNA in peripheral mononuclear cells in multiple sclerosis. Mult Scler. 1996;1:262-269.
-
(1996)
Mult Scler.
, vol.1
, pp. 262-269
-
-
Byskosh, P.V.1
Reder, A.T.2
-
21
-
-
44249102808
-
IFNβ-1b induces transient and variable gene expression in relapsing-remitting multiple sclerosis patients independent of neutralizing antibodies or changes in IFN receptor RNA expression
-
Reder AT, Veichko S, Yanaguchi KD, et al. IFNβ-1b induces transient and variable gene expression in relapsing-remitting multiple sclerosis patients independent of neutralizing antibodies or changes in IFN receptor RNA expression. J Interferon Cytokine Res. 2008;28:317-331.
-
(2008)
J Interferon Cytokine Res.
, vol.28
, pp. 317-331
-
-
Reder, A.T.1
Veichko, S.2
Yanaguchi, K.D.3
-
22
-
-
0038692013
-
Expression profiling identifies responder and non-responder phenotypes to interferon-ββin multiple sclerosis
-
Stürzebecher S, Wandinger KP, Rosenwald A, et al. Expression profiling identifies responder and non-responder phenotypes to interferon-ββin multiple sclerosis. Brain. 2003;126:1419-1429.
-
(2003)
Brain.
, vol.126
, pp. 1419-1429
-
-
Stürzebecher, S.1
Wandinger, K.P.2
Rosenwald, A.3
-
23
-
-
42049094003
-
IFN-β-regulated genes show abnormal expression in therapy-naïve relapsing-remitting MS mononuclear cells: Gene expression analysis employing all reported protein-protein interactions
-
Yamaguchi KD, Ruderman DL, Croze E, et al. IFN-β-regulated genes show abnormal expression in therapy-naïve relapsing-remitting MS mononuclear cells: gene expression analysis employing all reported protein-protein interactions. J Neuroimmunol. 2008;195:116-120.
-
(2008)
J Neuroimmunol.
, vol.195
, pp. 116-120
-
-
Yamaguchi, K.D.1
Ruderman, D.L.2
Croze, E.3
-
24
-
-
0037154192
-
Disease modifying therapies in multiple sclerosis. Report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology and the MS council for Clinical Practice Guidelines
-
Goodin DS, Frohman EM, Garmany GP, et al. Disease modifying therapies in multiple sclerosis. Report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology and the MS council for Clinical Practice Guidelines. Neurology. 2002;58:169-178.
-
(2002)
Neurology.
, vol.58
, pp. 169-178
-
-
Goodin, D.S.1
Frohman, E.M.2
Garmany, G.P.3
-
25
-
-
17644436776
-
Systemic recombinant human interferon-ββtreatment of relapsing-remitting multiple sclerosis: Pilot study analysis and six-year follow up
-
Knobler RL, Greenstein JL, Johnson KP, et al. Systemic recombinant human interferon-ββtreatment of relapsing-remitting multiple sclerosis: Pilot study analysis and six-year follow up. J Interferon Res. 1993;13:333-340.
-
(1993)
J Interferon Res.
, vol.13
, pp. 333-340
-
-
Knobler, R.L.1
Greenstein, J.L.2
Johnson, K.P.3
-
26
-
-
0027521002
-
Interferon beta-1b is effective in relapsing remitting multiple sclerosis. I. Clinical results of a multicenter, randomized, double-blind, placebo-controlled trial
-
IFNB Multiple Sclerosis Study Group
-
IFNB Multiple Sclerosis Study Group. Interferon beta-1b is effective in relapsing remitting multiple sclerosis. I. Clinical results of a multicenter, randomized, double-blind, placebo-controlled trial. Neurology. 1993;43:662-667.
-
(1993)
Neurology.
, vol.43
, pp. 662-667
-
-
-
27
-
-
0021035886
-
Rating neurologic impairment in multiple sclerosis: An expanded disability status scale (EDSS)
-
Kurtzke JF. Rating neurologic impairment in multiple sclerosis: an expanded disability status scale (EDSS). Neurology. 1983;33: 1444-1452.
-
(1983)
Neurology.
, vol.33
, pp. 1444-1452
-
-
Kurtzke, J.F.1
-
28
-
-
0027521002
-
Interferon beta-1b is effective in relapsing-remitting multiple sclerosis. II. MRI analysis results of a multi-center, randomized, double-blind, placebo-controlled trial
-
UBC MS/MRI Study Group
-
Paty DW, Li DKB, UBC MS/MRI Study Group, et al. Interferon beta-1b is effective in relapsing-remitting multiple sclerosis. II. MRI analysis results of a multi-center, randomized, double-blind, placebo-controlled trial. Neurology. 1993;43:662-667.
-
(1993)
Neurology.
, vol.43
, pp. 662-667
-
-
Paty, D.W.1
Li, D.K.B.2
-
29
-
-
0029161628
-
Interferon beta-1b in the treatment of multiple sclerosis: Final outcome of the randomized controlled trial
-
IFNB Multiple Sclerosis Study Group; University of British Columbia MS/MRI Analysis Group
-
IFNB Multiple Sclerosis Study Group; University of British Columbia MS/MRI Analysis Group. Interferon beta-1b in the treatment of multiple sclerosis: Final outcome of the randomized controlled trial. Neurology. 1996;45:1277-1285.
-
(1996)
Neurology.
, vol.45
, pp. 1277-1285
-
-
-
30
-
-
0032494792
-
Placebo-controlled multicenter randomized trial of interferon β-1b in treatment of secondary progressive multiple sclerosis
-
European Study Group on Interferon β-1b in Secondary Progressive MS
-
European Study Group on Interferon β-1b in Secondary Progressive MS. Placebo-controlled multicenter randomized trial of interferon β-1b in treatment of secondary progressive multiple sclerosis. Lancet. 1998;352:1491-1497.
-
(1998)
Lancet.
, vol.352
, pp. 1491-1497
-
-
-
31
-
-
8844222623
-
Interferon beta-1b in secondary progressive MS
-
North American Study Group on Interferon beta-1b in Secondary Progressive MS
-
North American Study Group on Interferon beta-1b in Secondary Progressive MS. Interferon beta-1b in secondary progressive MS. Neurology. 2004;63:1788-1795.
-
(2004)
Neurology.
, vol.63
, pp. 1788-1795
-
-
-
32
-
-
8844285856
-
Interferon beta-1b in secondary progressive MS. A combined analysis of the two trials
-
Kappos L, Weinshenker B, Pozzilli C, et al. Interferon beta-1b in secondary progressive MS. A combined analysis of the two trials. Neurology. 2004;63:1779-1787.
-
(2004)
Neurology.
, vol.63
, pp. 1779-1787
-
-
Kappos, L.1
Weinshenker, B.2
Pozzilli, C.3
-
33
-
-
33749661011
-
Treatment with interferon beta 1-b delays conversion to clinically definite and McDonald MS in patients with clinically isolated syndromes
-
Kappos L, Polman CH, Freedman MS, et al. Treatment with interferon beta 1-b delays conversion to clinically definite and McDonald MS in patients with clinically isolated syndromes. Neurology. 2006a;67:1242-1249.
-
(2006)
Neurology.
, vol.67
, pp. 1242-1249
-
-
Kappos, L.1
Polman, C.H.2
Freedman, M.S.3
-
34
-
-
0020686503
-
New diagnostic criteria for multiple sclerosis: Guidelines for research protocols
-
Poser CM, Paty DW, Scheinberg L, et al. New diagnostic criteria for multiple sclerosis: guidelines for research protocols. Ann Neurol. 1983;13:227-231.
-
(1983)
Ann Neurol.
, vol.13
, pp. 227-231
-
-
Poser, C.M.1
Paty, D.W.2
Scheinberg, L.3
-
35
-
-
0034955141
-
Recommended diagnostic criteria for multiple sclerosis: Guidelines from the International Panel on the diagnosis of multiple sclerosis
-
McDonald WI, Compston A, Edan G, et al. Recommended diagnostic criteria for multiple sclerosis: guidelines from the International Panel on the diagnosis of multiple sclerosis. Ann Neurol. 2001;50: 121-127.
-
(2001)
Ann Neurol.
, vol.50
, pp. 121-127
-
-
McDonald, W.I.1
Compston, A.2
Edan, G.3
-
36
-
-
34547497820
-
Effect of early versus delayed interferon beta-1b treatment on disability after a first clinical event suggestive of multiple sclerosis: A 3 year follow-up analysis of the BENEFIT study
-
Kappos L, Freedman MS, Polman CH, et al. Effect of early versus delayed interferon beta-1b treatment on disability after a first clinical event suggestive of multiple sclerosis: a 3 year follow-up analysis of the BENEFIT study. Lancet. 2007;370:389-397.
-
(2007)
Lancet.
, vol.370
, pp. 389-397
-
-
Kappos, L.1
Freedman, M.S.2
Polman, C.H.3
-
37
-
-
0008678962
-
Intramuscular interferon beta 1-a for disease progression in relapsing multiple sclerosis. The Multiple Sclerosis Collaborative Research Group (MSCRG)
-
Jacobs LD, Cookfair DL, Rudick RA, et al. Intramuscular interferon beta 1-a for disease progression in relapsing multiple sclerosis. The Multiple Sclerosis Collaborative Research Group (MSCRG). Ann Neurol. 1996;39:285-294.
-
(1996)
Ann Neurol.
, vol.39
, pp. 285-294
-
-
Jacobs, L.D.1
Cookfair, D.L.2
Rudick, R.A.3
-
38
-
-
8544249096
-
Impact of interferon beta-1a on neurologic disability in relapsing multiple sclerosis
-
Rudick RA, Goodkin DE, Jacobs LD, et al. Impact of interferon beta-1a on neurologic disability in relapsing multiple sclerosis. Neurology. 1997;49:358-363.
-
(1997)
Neurology.
, vol.49
, pp. 358-363
-
-
Rudick, R.A.1
Goodkin, D.E.2
Jacobs, L.D.3
-
39
-
-
0033663893
-
Neuropsychological effects of interferon β-1a in relapsing multiple sclerosis
-
Fischer JS, Priore RL, Jacobs LD, et al. Neuropsychological effects of interferon β-1a in relapsing multiple sclerosis. Ann Neurol. 2000;48:885-892.
-
(2000)
Ann Neurol.
, vol.48
, pp. 885-892
-
-
Fischer, J.S.1
Priore, R.L.2
Jacobs, L.D.3
-
40
-
-
0037069230
-
Eight-year follow-up study of brain atrophy in patients with MS
-
Fisher E, Rudick RA, Simon JH, et al. Eight-year follow-up study of brain atrophy in patients with MS. Neurology. 2002;59: 1412-1420.
-
(2002)
Neurology.
, vol.59
, pp. 1412-1420
-
-
Fisher, E.1
Rudick, R.A.2
Simon, J.H.3
-
41
-
-
0037180468
-
A randomized, double-blind, dose-comparison study of weekly interferon β-1a in relapsing MS
-
Clanet M, Radue EW, Kappos L, et al. A randomized, double-blind, dose-comparison study of weekly interferon β-1a in relapsing MS. Neurology. 2002;59:1507-1517.
-
(2002)
Neurology.
, vol.59
, pp. 1507-1517
-
-
Clanet, M.1
Radue, E.W.2
Kappos, L.3
-
42
-
-
10344255797
-
Interferon β-1a in relapsing multiple sclerosis: Four-year extension of the European IFNβ-1a dosecomparison study
-
Clanet M, Kappos L, Hartung HP, et al. Interferon β-1a in relapsing multiple sclerosis: four-year extension of the European IFNβ-1a dosecomparison study. Mult Scler. 2004;10:139-144.
-
(2004)
Mult Scler.
, vol.10
, pp. 139-144
-
-
Clanet, M.1
Kappos, L.2
Hartung, H.P.3
-
43
-
-
0037056364
-
Benefit of interferon β-1a on MSFC progression in secondary progressive MS
-
Cohen JA, Cutter GR, Fischer JS, et al. Benefit of interferon β-1a on MSFC progression in secondary progressive MS. Neurology. 2002;59:679-687.
-
(2002)
Neurology.
, vol.59
, pp. 679-687
-
-
Cohen, J.A.1
Cutter, G.R.2
Fischer, J.S.3
-
44
-
-
0032837796
-
The multiple sclerosis functional composite measure (MSFC): An integrated approach to MS clinical outcome assessment
-
Fischer JS, Rudick RA, Cutter GR, et al. The multiple sclerosis functional composite measure (MSFC): an integrated approach to MS clinical outcome assessment. Mult Scler. 1999;5:244-250.
-
(1999)
Mult Scler.
, vol.5
, pp. 244-250
-
-
Fischer, J.S.1
Rudick, R.A.2
Cutter, G.R.3
-
45
-
-
0034727059
-
Intramuscular interferon beta-1a therapy initiated during a first demyelinating event in multiple sclerosis
-
Jacobs LD, Beck RW, Simon JH, et al. Intramuscular interferon beta-1a therapy initiated during a first demyelinating event in multiple sclerosis. N Engl J Med. 2000;343:898-904.
-
(2000)
N Engl J Med.
, vol.343
, pp. 898-904
-
-
Jacobs, L.D.1
Beck, R.W.2
Simon, J.H.3
-
46
-
-
0037435526
-
Interferon β-1a in primary progressive MS. An exploratory, randomized, controlled trial
-
Leary SM, Miller DH, Stevenson VL, et al. Interferon β-1a in primary progressive MS. An exploratory, randomized, controlled trial. Neurology. 2003;60:44-51.
-
(2003)
Neurology.
, vol.60
, pp. 44-51
-
-
Leary, S.M.1
Miller, D.H.2
Stevenson, V.L.3
-
47
-
-
0345601517
-
Randomized double-blind placebo controlled study of interferon β-1a in relapsing/remitting multiple sclerosis
-
PRISMS (Prevention of Relapses and Disability by Interferon β-1a Subcutaneously in Multiple Sclerosis) Study Group
-
PRISMS (Prevention of Relapses and Disability by Interferon β-1a Subcutaneously in Multiple Sclerosis) Study Group. Randomized double-blind placebo controlled study of interferon β-1a in relapsing/remitting multiple sclerosis. Lancet. 1998;352: 1498-1504.
-
(1998)
Lancet.
, vol.352
, pp. 1498-1504
-
-
-
48
-
-
0032864616
-
Magnetic resonance imaging results of the PRISMS trial: A randomized, double-blind, placebo-controlled study of interferon-β1a in relapsing remitting multiple sclerosis
-
UBC MS/MRI Analysis Research Group and PRISMS Study Group
-
Li DKB, Paty DW, UBC MS/MRI Analysis Research Group and PRISMS Study Group. Magnetic resonance imaging results of the PRISMS trial: A randomized, double-blind, placebo-controlled study of interferon-β1a in relapsing remitting multiple sclerosis. Ann Neurol. 1999;46: 197-206.
-
(1999)
Ann Neurol.
, vol.46
, pp. 197-206
-
-
Li, D.K.B.1
Paty, D.W.2
-
49
-
-
0035954361
-
PRISMS-4: Long-term efficacy of interferon-β-1a in relapsing MS
-
PRISMS Study Group; University of British Columbia MS/MRI Analysis Group
-
PRISMS Study Group; University of British Columbia MS/MRI Analysis Group. PRISMS-4: Long-term efficacy of interferon-β-1a in relapsing MS. Neurology. 2001;56:1628-1636.
-
(2001)
Neurology.
, vol.56
, pp. 1628-1636
-
-
-
50
-
-
33749027200
-
Long-term subcutaneous interferon beta-1a therapy in patients with relapsing remitting MS
-
Kappos L, Traboulsee A, Constantinescu C, et al. Long-term subcutaneous interferon beta-1a therapy in patients with relapsing remitting MS. Neurology. 2006b;67:944-953.
-
(2006)
Neurology.
, vol.67
, pp. 944-953
-
-
Kappos, L.1
Traboulsee, A.2
Constantinescu, C.3
-
51
-
-
0344809968
-
Evidence of interferon β-1a dose response in relapsing-remitting MS
-
Once Weekly Interferon for MS Study Group (OWIMS)
-
Once Weekly Interferon for MS Study Group (OWIMS). Evidence of interferon β-1a dose response in relapsing-remitting MS. Neurology. 1999;53:679-686.
-
(1999)
Neurology.
, vol.53
, pp. 679-686
-
-
-
52
-
-
0035849496
-
Randomized controlled trial of interferon-beta-1a in secondary progressive MS. Clinical Results
-
Secondary Progressive Efficacy Clinical Trial of Recombinant 1-beta-1a in MS (SPECTRIMS) Study Group
-
Secondary Progressive Efficacy Clinical Trial of Recombinant 1-beta-1a in MS (SPECTRIMS) Study Group. Randomized controlled trial of interferon-beta-1a in secondary progressive MS. Clinical Results. Neurology. 2001;56:1496-1504.
-
(2001)
Neurology.
, vol.56
, pp. 1496-1504
-
-
-
53
-
-
0035849494
-
Randomized controlled trial of interferon-beta-1a in secondary progressive MS
-
Li DKB, Zhao GJ, Paty DW, et al. Randomized controlled trial of interferon-beta-1a in secondary progressive MS. Neurology. 2001;56:1505-1513.
-
(2001)
Neurology.
, vol.56
, pp. 1505-1513
-
-
Li, D.K.B.1
Zhao, G.J.2
Paty, D.W.3
-
54
-
-
0035912520
-
Effect of early interferon treatment on conversion to definite multiple sclerosis: A randomized trial
-
Comi F, Fillipi M, Barkhof F, et al. Effect of early interferon treatment on conversion to definite multiple sclerosis: a randomized trial. Lancet. 2001;357:1576-1582.
-
(2001)
Lancet.
, vol.357
, pp. 1576-1582
-
-
Comi, F.1
Fillipi, M.2
Barkhof, F.3
-
55
-
-
6944246720
-
Interferon beta-1a for brain tissue loss in patients at presentation with syndromes suggestive of multiple sclerosis: A randomized, double-blind, placebo controlled trial
-
Eillipi M, Rovaris M, Inglese M, et al. Interferon beta-1a for brain tissue loss in patients at presentation with syndromes suggestive of multiple sclerosis: a randomized, double-blind, placebo controlled trial. Lancet. 2004;364:1489-1496.
-
(2004)
Lancet.
, vol.364
, pp. 1489-1496
-
-
Eillipi, M.1
Rovaris, M.2
Inglese, M.3
-
56
-
-
0037181634
-
Every other day interferon beta-1b vs once-weekly interferon beta-1a for multiple sclerosis: Results of a 2-year prospective randomized multicenter study (INCOMIN)
-
Durelli L, Verdun E, Barbero P, et al. Every other day interferon beta-1b vs once-weekly interferon beta-1a for multiple sclerosis: results of a 2-year prospective randomized multicenter study (INCOMIN). Lancet. 2002;359:1453-1460.
-
(2002)
Lancet.
, vol.359
, pp. 1453-1460
-
-
Durelli, L.1
Verdun, E.2
Barbero, P.3
-
57
-
-
0037180479
-
Randomized, comparative study of interferon β1-a treatment regimens in MS: The EVIDENCE Trial
-
Panitch HS, Goodin DS, Francis G, et al. Randomized, comparative study of interferon β1-a treatment regimens in MS: the EVIDENCE Trial. Neurology. 2002;59:1496-1506.
-
(2002)
Neurology.
, vol.59
, pp. 1496-1506
-
-
Panitch, H.S.1
Goodin, D.S.2
Francis, G.3
-
58
-
-
27744516986
-
Benefits of high-dose, highfrequency interferon beta-1a in relapsing-remitting multiple sclerosis are sustained to 16 months: Final comparative results of the EVIDENCE trial
-
Panitch H, Goodin D, Francis G, et al. Benefits of high-dose, highfrequency interferon beta-1a in relapsing-remitting multiple sclerosis are sustained to 16 months: Final comparative results of the EVIDENCE trial. J Neurol Sci. 2005;239:67-74.
-
(2005)
J Neurol Sci.
, vol.239
, pp. 67-74
-
-
Panitch, H.1
Goodin, D.2
Francis, G.3
-
59
-
-
20844456591
-
Enhanced benefit of increasing interferon beta-1a dose and frequency in relapsing multiple sclerosis: The evidence study
-
Schwid SR, Thorpe J, Sharief M, et al. Enhanced benefit of increasing interferon beta-1a dose and frequency in relapsing multiple sclerosis: the evidence study. Arch Neurol. 2005;62:785-792.
-
(2005)
Arch Neurol.
, vol.62
, pp. 785-792
-
-
Schwid, S.R.1
Thorpe, J.2
Sharief, M.3
-
60
-
-
33646117499
-
A randomized study of two interferon-beta treatments in relapsing-remitting multiple sclerosis
-
Koch-Henriksen N, Sørensen PS, Christensen T, et al. A randomized study of two interferon-beta treatments in relapsing-remitting multiple sclerosis. Neurology. 2006;66:1056-1060.
-
(2006)
Neurology.
, vol.66
, pp. 1056-1060
-
-
Koch-Henriksen, N.1
Sørensen, P.S.2
Christensen, T.3
-
61
-
-
0033544299
-
Multiple sclerosis: Side effects of interferon beta therapy and their management
-
Walther EU, Hohlfeld R. Multiple sclerosis: side effects of interferon beta therapy and their management. Neurology. 1999;53: 1622-1627.
-
(1999)
Neurology.
, vol.53
, pp. 1622-1627
-
-
Walther, E.U.1
Hohlfeld, R.2
-
62
-
-
0029948580
-
Management of patients receiving interferon beta-1b for multiple sclerosis: Report of a consensus conference
-
Lublin FD, Whitaker JN, Eidelman BH, et al. Management of patients receiving interferon beta-1b for multiple sclerosis: report of a consensus conference. Neurology. 1996;46:12-18.
-
(1996)
Neurology.
, vol.46
, pp. 12-18
-
-
Lublin, F.D.1
Whitaker, J.N.2
Eidelman, B.H.3
-
63
-
-
0030683529
-
Managing side effects of interferon-beta in patients with relapsing-remitting multiple sclerosis
-
Munschauer FE, Kinkel RP. Managing side effects of interferon-beta in patients with relapsing-remitting multiple sclerosis. Clin Ther. 1997;19:883-893.
-
(1997)
Clin Ther.
, vol.19
, pp. 883-893
-
-
Munschauer, F.E.1
Kinkel, R.P.2
-
64
-
-
39549087978
-
Comparison of injection site pain and injection site reactions in relapsing-remitting multiple sclerosis patients treated with interferon beta-1a or 1b
-
Baum K, O'Leary C, Ferrer FC, et al. Comparison of injection site pain and injection site reactions in relapsing-remitting multiple sclerosis patients treated with interferon beta-1a or 1b. Mult Scler. 2007;13:1153-1160.
-
(2007)
Mult Scler.
, vol.13
, pp. 1153-1160
-
-
Baum, K.1
O'Leary, C.2
Ferrer, F.C.3
-
65
-
-
39549123498
-
Time of interferon-β-1a injection and duration of treatment affect clinical side effects and acute changes of plasma hormone and cytokine levels in multiple sclerosis patients
-
Kümpfel T, Schwan M, Pollmächer T, et al. Time of interferon-β-1a injection and duration of treatment affect clinical side effects and acute changes of plasma hormone and cytokine levels in multiple sclerosis patients. Mult Scler. 2007;13:1138-1145.
-
(2007)
Mult Scler.
, vol.13
, pp. 1138-1145
-
-
Kümpfel, T.1
Schwan, M.2
Pollmächer, T.3
-
66
-
-
0032976227
-
Ibuprofen treatment versus gradual introduction of interferon β1-b in patients with MS
-
Rice GP, Ebers GC, Lublin FD, et al. Ibuprofen treatment versus gradual introduction of interferon β1-b in patients with MS. Neurology. 1999;52:1893-1895.
-
(1999)
Neurology.
, vol.52
, pp. 1893-1895
-
-
Rice, G.P.1
Ebers, G.C.2
Lublin, F.D.3
-
67
-
-
1342266970
-
Liver injury associated with the β-interferons for MS: A comparison between three products
-
Tremlett HL, Yoshida EM, Oger J. Liver injury associated with the β-interferons for MS: a comparison between three products. Neurology. 2004;62:628-631.
-
(2004)
Neurology.
, vol.62
, pp. 628-631
-
-
Tremlett, H.L.1
Yoshida, E.M.2
Oger, J.3
-
68
-
-
0041854172
-
Hepatic reactions during treatment of multiple sclerosis with interferon-β-1a: Incidence and clinical significance
-
Francis GS, Grumser Y, Alteri E, et al. Hepatic reactions during treatment of multiple sclerosis with interferon-β-1a: incidence and clinical significance. Drug Safety. 2003;26:815-827.
-
(2003)
Drug Safety.
, vol.26
, pp. 815-827
-
-
Francis, G.S.1
Grumser, Y.2
Alteri, E.3
-
69
-
-
0035933123
-
Fulminant liver failure during interferon-beta treatment of multiple sclerosis
-
Yoshida EM, Rasmussen SL, Steinbrecher UP, et al. Fulminant liver failure during interferon-beta treatment of multiple sclerosis. Neurology. 2001;56:1416.
-
(2001)
Neurology.
, vol.56
, pp. 1416
-
-
Yoshida, E.M.1
Rasmussen, S.L.2
Steinbrecher, U.P.3
-
70
-
-
1642277003
-
The clinical impact of interferon beta antibodies in relapsing-remitting MS
-
Perini P, Calabrese M, Biasi G, et al. The clinical impact of interferon beta antibodies in relapsing-remitting MS. J Neurol. 2004;251:305-309.
-
(2004)
J Neurol.
, vol.251
, pp. 305-309
-
-
Perini, P.1
Calabrese, M.2
Biasi, G.3
-
71
-
-
0032893144
-
The evolution of neutralizing antibodies in multiple sclerosis patients treated with interferon β-1b
-
Rice GP, Paszner B, Oger J, et al. The evolution of neutralizing antibodies in multiple sclerosis patients treated with interferon β-1b. Neurology. 1999;52:1277-1279.
-
(1999)
Neurology.
, vol.52
, pp. 1277-1279
-
-
Rice, G.P.1
Paszner, B.2
Oger, J.3
-
72
-
-
0034881644
-
The significance of neutralizing antibodies in patients with multiple sclerosis treated with interferon beta
-
Rice G. The significance of neutralizing antibodies in patients with multiple sclerosis treated with interferon beta. Arch Neurol. 2001;58:1297-1298.
-
(2001)
Arch Neurol.
, vol.58
, pp. 1297-1298
-
-
Rice, G.1
-
73
-
-
0031674877
-
Neutralizing antibodies to interferon beta-1a and interferon beta-1b in MS patients are cross-reactive
-
Khan OA, Dhib-Jalbut SS. Neutralizing antibodies to interferon beta-1a and interferon beta-1b in MS patients are cross-reactive. Neurology. 1998;51:1698-1702.
-
(1998)
Neurology.
, vol.51
, pp. 1698-1702
-
-
Khan, O.A.1
Dhib-Jalbut, S.S.2
-
74
-
-
44049095565
-
Reduced immunogenicity with a new formulation of interferon of interferon-beta-1a (Rebif ®): 24-week results of a phase IIIb study
-
Giovannoni G, Barbarash OL, Jaber A, et al. Reduced immunogenicity with a new formulation of interferon of interferon-beta-1a (Rebif ®): 24-week results of a phase IIIb study. Mult Scler. 2006; 12(Suppl 1):S192.
-
(2006)
Mult Scler.
, vol.12
, Issue.SUPPL. 1
-
-
Giovannoni, G.1
Barbarash, O.L.2
Jaber, A.3
-
75
-
-
34147161297
-
Neutralizing antibodies to interferon beta: Assessment of their clinical and radiographic impact: An evidence report. Report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology
-
Goodin DS, Frohman EM, Hurwitz B, et al. Neutralizing antibodies to interferon beta: assessment of their clinical and radiographic impact: an evidence report. Report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology. Neurology. 2007;68:977-984.
-
(2007)
Neurology.
, vol.68
, pp. 977-984
-
-
Goodin, D.S.1
Frohman, E.M.2
Hurwitz, B.3
-
76
-
-
25444454284
-
The reproductive effects of beta interferon therapy in pregnancy: A longitudinal cohort
-
Boskovic R, Wide R, Wolpin J, et al. The reproductive effects of beta interferon therapy in pregnancy: a longitudinal cohort. Neurology. 2005;65:807-811.
-
(2005)
Neurology.
, vol.65
, pp. 807-811
-
-
Boskovic, R.1
Wide, R.2
Wolpin, J.3
-
77
-
-
33846071642
-
Predictors of quality of life among patients with multiple sclerosis: An Italian cross-sectional study
-
Patti F, Russo P, Pappalardo A, et al. Predictors of quality of life among patients with multiple sclerosis: an Italian cross-sectional study. J Neurol Sci. 2007;252:121-129.
-
(2007)
J Neurol Sci.
, vol.252
, pp. 121-129
-
-
Patti, F.1
Russo, P.2
Pappalardo, A.3
-
79
-
-
0035003051
-
Placebocontrolled clinical trials in multiple sclerosis: Ethical considerations
-
National Multiple Sclerosis Society (USA) Task Force on Placebo-Controlled Clinical Trials in MS
-
Lublin FD, Reingold SC, National Multiple Sclerosis Society (USA) Task Force on Placebo-Controlled Clinical Trials in MS. Placebocontrolled clinical trials in multiple sclerosis: ethical considerations. Ann Neurol. 2001;49:677-681.
-
(2001)
Ann Neurol.
, vol.49
, pp. 677-681
-
-
Lublin, F.D.1
Reingold, S.C.2
|