Dendrimer-entrapped gold nanoparticles as potential CT contrast agents for blood pool imaging

Nanoscale Research Letters

Volumn 7, Issue , 2012, Pages

  Wang, Han ^a   Zheng, Linfeng ^a   Guo, Rui ^b   Peng, Chen ^b   Shen, Mingwu ^b   Shi, Xiangyang ^b   Zhang, Guixiang ^a  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b DONGHUA UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CARDIOVASCULAR SYSTEM; DENDRIMERS; DIAGNOSTIC RADIOGRAPHY; FIBER OPTIC SENSORS; GOLD NANOPARTICLES; HIGH RESOLUTION TRANSMISSION ELECTRON MICROSCOPY; MAMMALS; METAL NANOPARTICLES; MOLECULAR IMAGING; PROBES;

BIOLOGICAL MOLECULE; BLOOD POOL IMAGING; CIRCULATION TIME; POLY(AMIDO AMINE); SERIAL DILUTIONS; URINARY SYSTEM; VASCULAR SYSTEM; X-RAY ATTENUATION;

COMPUTERIZED TOMOGRAPHY;

MUS;

EID: 84859416870     PISSN: 19317573     EISSN: 1556276X     Source Type: Journal    
DOI: 10.1186/1556-276X-7-190     Document Type: Article

References (43)

1. Garanger E, Hilderbrand SA, Blois JT, Sosnovik DE, Weissleder R, Josephson L: A DNA-binding Gd chelate for the detection of cell death by MRI. Chem Commun (Camb) 2009, 4444-4446.
2. Herschman HR: Molecular imaging: looking at problems, seeing solutions. Science 2003, 302:605-608.
3. Massoud TF, Gambhir SS: Molecular imaging in living subjects: seeing fundamental biological processes in a new light. Genes Dev 2003, 17:545-580.
4. Weissleder R: Molecular imaging: exploring the next frontier. Radiology 1999, 212:609-614.
5. Liu CX: Research and development of nanopharmaceuticals in China. Nano Biomed Eng 2009, 1:1-12.
6. Hainfeld JF, Slatkin DN, Smilowitz HM: The use of gold nanoparticles to enhance radiotherapy in mice. Phys Med Biol 2004, 49:N309-N315.
7. Loo C, Lowery A, Halas NJ, West J, Drezek R: Immunotargeted nanoshells for integrated cancer imaging and therapy. Nano Letters 2005, 5:709-711.
8. Aryal S, Pilla S, Gong S: Multifunctional nano-micelles formed by amphiphilic gold-polycaprolactone-methoxy poly(ethylene glycol) (Au-PCL-MPEG) nanoparticles for potential drug delivery applications. J Nanosci Nanotechnol 2009, 9:5701-5708.
9. Curley SA, Cherukuri P, Briggs K, Patra CR, Upton M, Dolson E, Mukherjee P: Noninvasive radiofrequency field-induced hyperthermic cytotoxicity in human cancer cells using cetuximab-targeted gold nanoparticles. J Exp Ther Oncol 2008, 7:313-26.
10. Chen DF, Wu XB, Wang JX, Han BS, Zhu P, Peng CH: Morphological observation of interaction between PAMAM dendrimer modified single walled carbon nanotubes and pancreatic cancer cells. Nano Biomed Eng 2010, 2:61-69.
11. Chen SH, Ji YX, Lian Q, Wen YL, Shen HB, Jia NQ: Gold nanorods coated with multilayer polyelectrolyte as intracellular delivery vector of antisense oligonucleotides. Nano Biomed Eng 2010, 2:15-23.
12. Feng LL, Gao G, Huang P, Wang K, Wang XS, Luo T, Zhang CL: Optical properties and catalytic activity of bimetallic gold-silver nanoparticles. Nano Biomed Eng 2010, 2:258-267.
13. He M, Huang P, Zhang CL, Hu HY, Bao CC, Gao G, He R, Cui DX: Dual phase-controlled synthesis of uniform lanthanide-doped NaGdF4 upconversion nanocrystals via an OA/ionic liquid two-phase system for in vivo dual-modality imaging. Adv Funct Mater, in press.
14. Zhang XQ, Pan BF, Wang K, Ruan J, Bao CC, Yang H, He R, Cui DX: Electrochemical property and cell toxicity of gold electrode modified by monolayer PAMAM encapsulated gold nanorods. Nano Biomed Eng 2010, 2:182-188.
15. Li ZM, Huang P, Zhang XJ, Lin J, Yang S, Liu B, Gao F, Xi P, Ren QS, Cui DX: RGD-conjugated dendrimer-modified gold nanorods for in vivo tumor targeting and photothermal therapy. Mol Pharmaceut 2010, 7:94-104.
16. Huang P, Li ZM, Lin J, Yang DP, Gao G, Xu C, Bao L, Zhang CL, Wang K, Song H, Hu HY, Cui DX: Photosensitizer-conjugated magnetic nanoparticles for in vivo simultaneous magnetofluorescent imaging and targeting therapy. Biomaterials 2011, 32:3447-3458.
17. Gao G, Wu HX, Zhang YX, Luo T, Feng LL, Huang P, He M, Cui DX: Synthesis of ultrasmall nucleotide-functionalized superparamagnetic gamma-Fe(2)O(3) nanoparticles. Crystengcomm 2011, 13:4810-4813.
18. Huang P, Yang DP, Zhang CL, Lin J, He M, Bao L, Cui DX: Protein-directed one-pot synthesis of Ag microspheres with good biocompatibility and enhancement of radiation effects on gastric cancer cells. Nanoscale 2011, 3:3623-3626.
19. Tables of X-ray mass attenuation coefficients and mass energy-absorption coefficients from 1 keV to 20 MeV for elements Z = 1 to 92 and 48 additional substances of dosimetric interest [http://www.nist.gov/pml/data/xraycoef/index.cfm]
20. Connor EE, Mwamuka J, Gole A, Murphy CJ, Wyatt MD: Gold nanoparticles are taken up by human cells but do not cause acute cytotoxicity. Small 2005, 1:325-327.
21. Shukla R, Bansal V, Chaudhary M, Basu A, Bhonde RR, Sastry M: Biocompatibility of gold nanoparticles and their endocytotic fate inside the cellular compartment: A microscopic overview. Langmuir 2005, 21:10644-10654.
22. Marchal F, Pic E, Pons T, Dubertret B, Bolotine L, Guillemin F: Quantum dots in oncological surgery: the future for surgical margin status. Bull Cancer 2008, 95:1149-1153.
23. Patra CR, Bhattacharya R, Mukhopadhyay D, Mukherjee P: Fabrication of gold nanoparticles for targeted therapy in pancreatic cancer. Adv Drug Deliv Rev 62:346-361.
24. Popovtzer R, Agrawal A, Kotov NA, Popovtzer A, Balter J, Carey TE, Kopelman R: Targeted gold nanoparticles enable molecular CT imaging of cancer. Nano Lett 2008, 8:4593-4596.
25. Byrne JD, Betancourt T, Brannon-Peppas L: Active targeting schemes for nanoparticle systems in cancer therapeutics. Adv Drug Deliv Rev 2008, 60:1615-1626.
26. Kim D, Park S, Lee JH, Jeong YY, Jon S: Antibiofouling polymer-coated gold nanoparticles as a contrast agent for in vivo X-ray computed tomography imaging. J Am Chem Soc 2007, 129:7661-7665.
27. Kobayashi H, Brechbiel MW: Nano-sized MRI contrast agents with dendrimer cores. Adv Drug Deliv Rev 2005, 57:2271-2286.
28. Hong S, Bielinska AU, Mecke A, Keszler B, Beals JL, Shi X, Balogh L, Orr BG, Baker JR, Jr, Banaszak Holl MM: Interaction of poly(amidoamine) dendrimers with supported lipid bilayers and cells: hole formation and the relation to transport. Bioconjug Chem 2004, 15:774-782.
29. Majoros IJ, Myc A, Thomas T, Mehta CB, Baker JR, Jr: PAMAM dendrimer-based multifunctional conjugate for cancer therapy: synthesis, characterization, and functionality. Biomacromolecules 2006, 7:572-579.
30. Shi X, Wang S, Meshinchi S, Van Antwerp ME, Bi X, Lee I, Baker JR, Jr: Dendrimer-entrapped gold nanoparticles as a platform for cancer-cell targeting and imaging. Small 2007, 3:1245-1252.
31. Shi XY, Ganser TR, Sun K, Balogh LP, Baker JR, Jr: Characterization of crystalline dendrimer-stabilized gold nanoparticles. Nanotechnology 2006, 17:1072-1078.
32. Shi XY, Lee I, Baker JR, Jr: Acetylation of dendrimer-entrapped gold and silver nanoparticles. J Mater Chem 2008, 18:586-593.
33. Hainfeld JF, Slatkin DN, Focella TM, Smilowitz HM: Gold nanoparticles: a new X-ray contrast agent. Brit J Radiol 2006, 79:248-253.
34. Xu CJ, Tung GA, Sun SH: Size and concentration effect of gold nanoparticles on X-ray attenuation as measured on computed tomography. Chem Mater 2008, 20:4167-4169.
35. Guo R, Wang H, Peng C, Shen MW, Pan MJ, Cao XY, Zhang GX, Shi XY: X-ray attenuation property of dendrimer-entrapped gold nanoparticles. J Phys Chem C 2010, 114:50-56.
36. Shi XY, Wang SH, Sun HP, Baker JR, Jr: Improved biocompatibility of surface functionalized dendrimer-entrapped gold nanoparticles. Soft Matter 2007, 3:71-74.
37. Cormode DP, Skajaa T, van Schooneveld MM, Koole R, Jarzyna P, Lobatto ME, Calcagno C, Barazza A, Gordon RE, Zanzonico P, Fisher EA, Fayad ZA, Mulder WJ: Nanocrystal core high-density lipoproteins: a multimodality contrast agent platform. Nano Letters 2008, 8:3715-3723.
38. Hall CJ, Schultke E, Rigon L, Ataelmannan K, Rigley S, Menk R, Arfellie F, Tromba G, Pearson S, Wilkinson S, Round A, Crittell S, Griebel R, Juurlink BH: Synchrotron-based in vivo tracking of implanted mammalian cells. Eur J Radiol 2008, 68:S156-S159.
39. Barrett T, Kobayashi H, Brechbiel M, Choyke PL: Macromolecular MRI contrast agents for imaging tumor angiogenesis. Eur J Radiol 2006, 60:353-366.
40. Tong RT, Boucher Y, Kozin SV, Winkler F, Hicklin DJ, Jain RK: Vascular normalization by vascular endothelial growth factor receptor 2 blockade induces a pressure gradient across the vasculature and improves drug penetration in tumors. Cancer Res 2004, 64:3731-3736.
41. Dong Q, Hurst DR, Weinmann HJ, Chenevert TL, Londy FJ, Prince MR: Magnetic resonance angiography with gadomer-17. An animal study original investigation. Invest Radiol 1998, 33:699-708.
42. Sato N, Kobayashi H, Hiraga A, Saga T, Togashi K, Konishi J, Brechbiel MW: Pharmacokinetics and enhancement patterns of macromolecular MR contrast agents with various sizes of polyamidoamine dendrimer cores. Magn Reson Med 2001, 46:1169-1173.
43. Guo R, Wang H, Peng C, Shen M, Zheng L, Zhang G, Shi X: Enhanced X-ray attenuation property of dendrimer-entrapped gold nanoparticles complexed with diatrizoic acid. J Mater Chem 2011, 21:5120-5127.