Curcumin protects nigrostriatal dopaminergic neurons and reduces glial activation in 6-hydroxydopamine hemiparkinsonian mice model

International Journal of Neuroscience

Volumn 122, Issue 5, 2012, Pages 263-270

  Tripanichkul, Wanida ^a   Jaroensuppaperch, Em Orn ^a  

^a SRINAKHARINWIROT UNIVERSITY   (Thailand)

Author keywords

6 OHDA; astrocyte; curcumin; microglia; striatum; substantia nigra pars compacta

Indexed keywords

CURCUMIN; OXIDOPAMINE; TYROSINE 3 MONOOXYGENASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORPUS STRIATUM; DOPAMINERGIC NERVE CELL; GLIA; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MACROGLIA; MALE; MOUSE; NEUROPROTECTION; NIGRONEOSTRIATAL SYSTEM; NONHUMAN; PARKINSONISM; SUBSTANTIA NIGRA;

ANIMALS; CORPUS STRIATUM; CURCUMIN; DISEASE MODELS, ANIMAL; DOPAMINERGIC NEURONS; MALE; MICE; MICE, INBRED ICR; NEURAL PATHWAYS; NEUROGLIA; PARKINSONIAN DISORDERS; SUBSTANTIA NIGRA; TREATMENT OUTCOME;

EID: 84859395842     PISSN: 00207454     EISSN: 15635279     Source Type: Journal    
DOI: 10.3109/00207454.2011.648760     Document Type: Article

References (39)

1. DeLong MR. Primate models of movement disorders of basal ganglia origin. Trends Neurosci. 1990;13(7):281-5. (Pubitemid 20193459)
2. Kurkowska-Jastrzebska I, Litwin T, Joniec I, Ciesielska A, Przybyłkowski A, Członkowski A, Członkowska A. Dexamethasone protects against dopaminergic neurons damage in a mouse model of Parkinson's disease. Int Immunopharmacol. 2004;4(10-11):1307-18. (Pubitemid 39094405)
3. McGeer PL, Itagaki S, Akiyama H, McGeer EG. Rate of cell death in parkinsonism indicates active neuropathological process. Ann Neurol. 1988;24(4):574-6.
4. Tripanichkul W, Sripanichkulchai K, Finkelstein DI. Estrogen down-regulates glial activation in male mice following 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine intoxication. Brain Res. 2006;1084(1):28-37.
5. Knott C, Stern G, Wilkin GP. Inflammatory regulators in Parkinson's disease: iNOS, lipocortin-1, and cyclooxygenases-1 and -2. Mol Cell Neurosci. 2000;16(6):724-39. (Pubitemid 32062060)
6. Liberatore GT, Jackson-Lewis V, Vukosavic S, Mandir AS, Vila M, McAuliffe WG, Dawson VL, Dawson TM, Przedborski S. Inducible nitric oxide synthase stimulates dopaminergic neurodegeneration in the MPTP model of Parkinson disease. Nat Med. 1999;5(12):1403-9.
7. Norenberg MD. Reactive astrocytosis. In: Michael Aschner and Harold K. Kimelberg (eds.). The role of glia in neurotoxicity. Boca Raton (FL): CRC Press; 1996. p. 93-107.
8. Qin L, Liu Y, Cooper C, Liu B, Wilson B, Hong JS. Microglia enhance beta-amyloid peptide-induced toxicity in cortical and mesencephalic neurons by producing reactive oxygen species. J Neurochem. 2002;83(4):973-83. (Pubitemid 35316048)
9. Frautschy SA, Hu W, Kim P, Miller SA, Chu T, Harris-White ME, Cole GM. Phenolic anti-inflammatory antioxidant reversal of Abeta-induced cognitive deficits and neuropathology. Neurobiol Aging. 2001;22(6):993-1005. (Pubitemid 34070638)
10. Yang S, Zhang D, Yang Z, Hu X, Qian S, Liu J, Wilson B, Block M, Hong JS. Curcumin protects dopaminergic neuron against LPS induced neurotoxicity in primary rat neuron/glia culture. Neurochem Res. 2008;33(10):2044-53.
11. Rajeswari A. Curcumin protects mouse brain from oxidative stress caused by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Eur Rev Med Pharmacol Sci. 2006;10(4):157-61. (Pubitemid 44468939)
12. Franklin KBJ, Paxinos G. The mouse brain in the stereotaxic coordinates. San Diego (CA): Academic Press; 1997.
13. Gundersen HJ, Bagger P, Bendtsen TF, Evans, SM, Korbo, L, Marcussen, N, Møller, A, Nielsen, K, Nyengaard, JR, Pakkenberg, B, Sørensen, FB, Vesterby, A, West, MJ. The new stereological tools: disector, fractionator, nucleator and point sampled intercepts and their use in pathological research and diagnosis. APMIS. 1988;96(10):857-81.
14. West MJ, Ostergaard K, Andreassen OA, Finsen, B. Estimation of the number of somatostatin neurons in the striatum: an in situ hybridization study using the optical fractionator method. J Comp Neurol. 1996;370(1):11-22. (Pubitemid 26192341)
15. Farkas E, Institoris A, Domoki F, Mihály, A, Luiten, PG, Bari, F. Diazoxide and dimethyl sulphoxide prevent cerebral hypoperfusion-related learning dysfunction and brain damage after carotid artery occlusion. Brain Res. 2004;1008(2):252-60. (Pubitemid 38624056)
16. Zbarsky V, Datla KP, Parkar S, Rai, DK, Aruoma, OI, Dexter, DT. Neuroprotective properties of the natural phenolic antioxidants curcumin and naringenin but not quercetin and fisetin in a 6-OHDA model of Parkinson's disease. Free Radic Res. 2005;39(10):1119-25. (Pubitemid 41358566)
17. Xu Y, Ku BS, Yao HY, Lin, YH, Zhang, YH, L Xu. The effects of curcumin on depressive-like behaviors in mice. Eur J Pharmacol. 2005;518(1):40-6. (Pubitemid 40968146)
18. Wang J, Du XX, Jiang H, Xie, JX. Curcumin attenuates 6-hydroxydopamine- induced cytotoxicity by anti-oxidation and nuclear factor-kappa B modulation in MES23.5 cells. Biochem Pharmacol. 2009;78(2):178-83.
19. Yu S, Zheng W, Xin N, Chi, ZH, Wang, NQ, Nie, YX, Feng, WY, Wang, ZY. Curcumin prevents dopaminergic neuronal death through inhibition of the c-Jun N-terminal kinase pathway. Rejuvenation Res. 2010;13(1):55-64.
20. Gehrmann J, Schoen SW, Kreutzberg GW. Lesion of the rat entorhinal cortex leads to a rapid microglial reaction in the dentate gyrus. A light and electron microscopical study. Acta Neuropathol. 1991;82(6):442-55.
21. Streit WJ, Kreutzberg GW. Response of endogenous glial cells to motor neuron degeneration induced by toxic ricin. J Comp Neurol. 1988;268(2):248-63.
22. Forno LS, DeLanney LE, Irwin I, Di Monte, D, Langston, JW. Astrocytes and Parkinson's disease. Prog Brain Res. 1992;94:429-36. (Pubitemid 23026667)
23. He Y, Appel S, LeW.Minocycline inhibits microglial activation and protects nigral cells after 6-hydroxydopamine injection into mouse striatum. Brain Res. 2001;909(1-2):187-93. (Pubitemid 32710132)
24. Wu DC, Jackson-Lewis V, Vila M, Tieu, K, Teismann, P, Vadseth, C, Choi, DK, Ischiropoulos, H, Przedborski, S. Blockade of microglial activation is neuroprotective in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson disease. J Neurosci. 2002;22(5):1763-71. (Pubitemid 35386294)
25. Thanos S, Mey J, Wild M. Treatment of the adult retina with microglia-suppressing factors retards axotomy-induced neuronal degradation and enhances axonal regeneration in vivo and in vitro. J Neurosci. 1993;13(2):455-66. (Pubitemid 23045132)
26. Tateishi N, Mori T, Kagamiishi Y, Satoh, S, Katsube, N, Morikawa, E, Morimoto, T, Matsui, T, Asano, T. Astrocytic activation and delayed infarct expansion after permanent focal ischemia in rats. Part II: suppression of astrocytic activation by a novel agent (R)-(-)-2-propyloctanoic acid (ONO-2506) leads to mitigation of delayed infarct expansion and early improvement of neurologic deficits. J Cereb Blood Flow Metab. 2002;22(6):723-34. (Pubitemid 34596465)
27. Botchkina GI, Meistrell ME, 3rd, Botchkina IL, Tracey, KJ. Expression of TNF and TNF receptors (p55 and p75) in the rat brain after focal cerebral ischemia. Mol Med. 1997;3(11):765-81. (Pubitemid 28047420)
28. Ho A, Blum M. Induction of interleukin-1 associated with compensatory dopaminergic sprouting in the denervated striatum of young mice: model of aging and neurodegenerative disease. J Neurosci. 1998;18(15):5614-29. (Pubitemid 28341342)
29. Kohutnicka M, Lewandowska E, Kurkowska-Jastrzebska I, Członkowski, A, Członkowska, A. Microglial and astrocytic involvement in a murine model of Parkinson's disease induced by 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine (MPTP). Immunopharmacology. 1998;39(3):167-80. (Pubitemid 28432061)
30. Lau LT, Yu AC. Astrocytes produce and release interleukin-1, interleukin-6, tumor necrosis factor alpha and interferongamma following traumatic and metabolic injury. J Neurotrauma. 2001;18(3):351-9. (Pubitemid 32230637)
31. Orzylowska O, Oderfeld-Nowak B, ZarembaM, Januszewski, S, Mossakowski, M. Prolonged and concomitant induction of astroglial immunoreactivity of interleukin-1beta and interleukin-6 in the rat hippocampus after transient global ischemia. Neurosci Lett. 1999;263(1):72-6. (Pubitemid 29138966)
32. Schmidt B, Stoll G, Toyka KV, Hartung, HP. Rat astrocytes express interferon-gamma immunoreactivity in normal optic nerve and after nerve transection. Brain Res. 1990;515(1-2):347-50. (Pubitemid 20176140)
33. Chao CC, Hu S, Molitor TW, Shaskan, EG, Peterson, PK. Activated microglia mediate neuronal cell injury via a nitric oxide mechanism. J Immunol. 1992;149(8):2736-41.
34. Colton CA, Keri JE, Chen WT, Monsky, WL. Protease production by cultured microglia: substrate gel analysis and immobilized matrix degradation. J Neurosci Res. 1993;35(3):297-304. (Pubitemid 23182729)
35. Mollace V, Muscoli C, Rotiroti D, Nisticó, G. Spontaneous induction of nitric oxide- and prostaglandin E2-release by hypoxic astroglial cells is modulated by interleukin 1 beta. Biochem Biophys Res Commun. 1997;238(3):916-9. (Pubitemid 27472677)
36. Piani D, Frei K, Do KQ, Cuénod, M, Fontana, A. Murine brain macrophages induced NMDA receptor mediated neurotoxicity in vitro by secreting glutamate. Neurosci Lett. 1991;133(2):159-62.
37. Ambegaokar SS, Wu L, Alamshahi K, Lau, J, Jazayeri, L, Chan, S, Khanna, P, Hsieh, E, Timiras, PS. Curcumin inhibits dose-dependently and time-dependently neuroglial cell proliferation and growth. Neuro Endocrinol Lett. 2003;24(6):469-73. (Pubitemid 38035100)
38. Lin MS, Lee YH, Chiu WT, Hung, KS. Curcumin provides neuroprotection after spinal cord injury. J Surg Res. 2009;166(2):280-89.
39. Zhang LJ, Wu CF, Meng XL, Yuan, D, Cai, XD, Wang, QL, Yang, JY. Comparison of inhibitory potency of three different curcuminoid pigments on nitric oxide and tumor necrosis factor production of rat primary microglia induced by lipopolysaccharide. Neurosci Lett. 2008;447(1):48-53.