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Volumn 22, Issue 4, 2012, Pages 616-619

Rejuvenating liver and pancreas through cell transdifferentiation

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; AUTOTRANSPLANTATION; CELL TRANSDIFFERENTIATION; CYTOLOGY; GENETICS; HUMAN; LIVER; LIVER CELL; MESENCHYMAL STEM CELL; METHODOLOGY; PANCREAS; PANCREAS ISLET BETA CELL; PHYSIOLOGY; PLURIPOTENT STEM CELL; REGENERATION; REGENERATIVE MEDICINE;

EID: 84859368332     PISSN: 10010602     EISSN: 17487838     Source Type: Journal    
DOI: 10.1038/cr.2012.33     Document Type: Article
Times cited : (16)

References (18)
  • 1
    • 78951478823 scopus 로고    scopus 로고
    • Dedifferentiation, transdifferentiation and reprogramming: Three routes to regeneration
    • Jopling C, Boue S, Izpisua Belmonte JC. Dedifferentiation, transdifferentiation and reprogramming: Three routes to regeneration. Nat Rev Mol Cell Biol 2011; 12:79-89.
    • (2011) Nat Rev Mol Cell Biol , vol.12 , pp. 79-89
    • Jopling, C.1    Boue, S.2    Izpisua Belmonte, J.C.3
  • 2
    • 79952261648 scopus 로고    scopus 로고
    • Stem cells: The dark side of induced pluripotency
    • Pera MF. Stem cells: The dark side of induced pluripotency. Nature 2011; 471:46-47.
    • (2011) Nature , vol.471 , pp. 46-47
    • Pera, M.F.1
  • 3
    • 79960649307 scopus 로고    scopus 로고
    • Direct conversion of mouse fibroblasts to hepatocyte-like cells by defined factors
    • Sekiya S, Suzuki A. Direct conversion of mouse fibroblasts to hepatocyte-like cells by defined factors. Nature 2011; 475:390-393.
    • (2011) Nature , vol.475 , pp. 390-393
    • Sekiya, S.1    Suzuki, A.2
  • 4
    • 79960637387 scopus 로고    scopus 로고
    • Induction of functional hepatocyte-like cells from mouse fibroblasts by defined factors
    • Huang P, He Z, Ji S, et al. Induction of functional hepatocyte-like cells from mouse fibroblasts by defined factors. Nature 2011; 475:386-389.
    • (2011) Nature , vol.475 , pp. 386-389
    • Huang, P.1    He, Z.2    Ji, S.3
  • 5
    • 10644283018 scopus 로고    scopus 로고
    • In vitro hepatic differentiation of human mesenchymal stem cells
    • Lee KD, Kuo TK, Whang-Peng J, et al. In vitro hepatic differentiation of human mesenchymal stem cells. Hepatology 2004; 40:1275-1284.
    • (2004) Hepatology , vol.40 , pp. 1275-1284
    • Lee, K.D.1    Kuo, T.K.2    Whang-Peng, J.3
  • 6
    • 33749048777 scopus 로고    scopus 로고
    • In vitro differentiation of human placenta- derived multipotent cells into hepatocyte-like cells
    • Chien CC, Yen BL, Lee FK, et al. In vitro differentiation of human placenta- derived multipotent cells into hepatocyte-like cells. Stem Cells 2006; 24:1759-1768.
    • (2006) Stem Cells , vol.24 , pp. 1759-1768
    • Chien, C.C.1    Yen, B.L.2    Lee, F.K.3
  • 7
    • 79952199658 scopus 로고    scopus 로고
    • HNF-4alpha determines hepatic differentiation of human mesenchymal stem cells from bone marrow
    • Chen ML, Lee KD, Huang HC, et al. HNF-4alpha determines hepatic differentiation of human mesenchymal stem cells from bone marrow. World J Gastroenterol 2010; 16:5092-5103.
    • (2010) World J Gastroenterol , vol.16 , pp. 5092-5103
    • Chen, M.L.1    Lee, K.D.2    Huang, H.C.3
  • 8
    • 49649087696 scopus 로고    scopus 로고
    • Hepatic differentiation of human bone marrow-derived mesenchymal stem cells by tetracycline-regulated hepatocyte nuclear factor 3beta
    • Ishii K, Yoshida Y, Akechi Y, et al. Hepatic differentiation of human bone marrow-derived mesenchymal stem cells by tetracycline-regulated hepatocyte nuclear factor 3beta. Hepatology 2008; 48:597-606.
    • (2008) Hepatology , vol.48 , pp. 597-606
    • Ishii, K.1    Yoshida, Y.2    Akechi, Y.3
  • 9
    • 34547461813 scopus 로고    scopus 로고
    • Adipose tissue-derived mesenchymal stem cells as a source of human hepatocytes
    • Banas A, Teratani T, Yamamoto Y, et al. Adipose tissue-derived mesenchymal stem cells as a source of human hepatocytes. Hepatology 2007; 46:219-228.
    • (2007) Hepatology , vol.46 , pp. 219-228
    • Banas, A.1    Teratani, T.2    Yamamoto, Y.3
  • 10
    • 53349178722 scopus 로고    scopus 로고
    • In vivo reprogramming of adult pancreatic exocrine cells to beta-cells
    • Zhou Q, Brown J, Kanarek A, Rajagopal J, Melton DA. In vivo reprogramming of adult pancreatic exocrine cells to beta-cells. Nature 2008; 455:627-632.
    • (2008) Nature , vol.455 , pp. 627-632
    • Zhou, Q.1    Brown, J.2    Kanarek, A.3    Rajagopal, J.4    Melton, D.A.5
  • 11
    • 84857888840 scopus 로고    scopus 로고
    • Reprogramming of pancreatic exocrine cells towards a beta cell character using Pdx1, Ngn3 and MafA
    • Akinci E, Banga A, Greder LV, Dutton JR, Slack JM. Reprogramming of pancreatic exocrine cells towards a beta cell character using Pdx1, Ngn3 and MafA. Biochem J 2011; 442:539-550.
    • (2011) Biochem J , vol.442 , pp. 539-550
    • Akinci, E.1    Banga, A.2    Greder, L.V.3    Dutton, J.R.4    Slack, J.M.5
  • 12
    • 77951611220 scopus 로고    scopus 로고
    • Conversion of adult pancreatic alpha-cells to beta-cells after extreme beta-cell loss
    • Thorel F, Nepote V, Avril I, et al. Conversion of adult pancreatic alpha-cells to beta-cells after extreme beta-cell loss. Nature 2010; 464:1149-1154.
    • (2010) Nature , vol.464 , pp. 1149-1154
    • Thorel, F.1    Nepote, V.2    Avril, I.3
  • 13
    • 78149437689 scopus 로고    scopus 로고
    • Dexamethasone treatment induces the reprogramming of pancreatic acinar cells to hepatocytes and ductal cells
    • Al-Adsani A, Burke ZD, Eberhard D, et al. Dexamethasone treatment induces the reprogramming of pancreatic acinar cells to hepatocytes and ductal cells. PLoS One 2010; 5:e13650.
    • (2010) PLoS One , vol.5
    • Al-Adsani, A.1    Burke, Z.D.2    Eberhard, D.3
  • 14
    • 77953575574 scopus 로고    scopus 로고
    • Glucocorticoid-dependent transdifferentiation of pancreatic progenitor cells into hepatocytes is dependent on transient suppression of WNT signalling
    • Wallace K, Marek CJ, Hoppler S, Wright MC. Glucocorticoid-dependent transdifferentiation of pancreatic progenitor cells into hepatocytes is dependent on transient suppression of WNT signalling. J Cell Sci 2010; 123:2103-2110.
    • (2010) J Cell Sci , vol.123 , pp. 2103-2110
    • Wallace, K.1    Marek, C.J.2    Hoppler, S.3    Wright, M.C.4
  • 15
    • 0034068602 scopus 로고    scopus 로고
    • Pancreatic and duodenal homeobox gene 1 induces expression of insulin genes in liver and ameliorates streptozotocin- induced hyperglycemia
    • Ferber S, Halkin A, Cohen H, et al. Pancreatic and duodenal homeobox gene 1 induces expression of insulin genes in liver and ameliorates streptozotocin- induced hyperglycemia. Nat Med 2000; 6:568-572.
    • (2000) Nat Med , vol.6 , pp. 568-572
    • Ferber, S.1    Halkin, A.2    Cohen, H.3
  • 16
    • 70450235041 scopus 로고    scopus 로고
    • Exendin-4 promotes liver cell proliferation and enhances the PDX-1-induced liver to pancreas transdifferentiation process
    • Aviv V, Meivar-Levy I, Rachmut IH, Rubinek T, Mor E, Ferber S. Exendin-4 promotes liver cell proliferation and enhances the PDX-1-induced liver to pancreas transdifferentiation process. J Biol Chem 2009; 284:33509-33520.
    • (2009) J Biol Chem , vol.284 , pp. 33509-33520
    • Aviv, V.1    Meivar-Levy, I.2    Rachmut, I.H.3    Rubinek, T.4    Mor, E.5    Ferber, S.6
  • 17
    • 15944417831 scopus 로고    scopus 로고
    • PDX-1/VP16 fusion protein, together with NeuroD or Ngn3, markedly induces insulin gene transcription and ameliorates glucose tolerance
    • Kaneto H, Nakatani Y, Miyatsuka T, et al. PDX-1/VP16 fusion protein, together with NeuroD or Ngn3, markedly induces insulin gene transcription and ameliorates glucose tolerance. Diabetes 2005; 54:1009-1022.
    • (2005) Diabetes , vol.54 , pp. 1009-1022
    • Kaneto, H.1    Nakatani, Y.2    Miyatsuka, T.3
  • 18
    • 61749094740 scopus 로고    scopus 로고
    • Neurogenin3 is sufficient for transdetermination of hepatic progenitor cells into neo-islets in vivo but not transdifferentiation of hepatocytes
    • Yechoor V, Liu V, Espiritu C, et al. Neurogenin3 is sufficient for transdetermination of hepatic progenitor cells into neo-islets in vivo but not transdifferentiation of hepatocytes. Dev Cell 2009; 16:358-373.
    • (2009) Dev Cell , vol.16 , pp. 358-373
    • Yechoor, V.1    Liu, V.2    Espiritu, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.