Glucocorticoid-dependent transdifferentiation of pancreatic progenitor cells into hepatocytes is dependent on transient suppression of WNT signalling

Journal of Cell Science

Volumn 123, Issue 12, 2010, Pages 2103-2110

  Wallace, Karen ^a   Marek, Carylyn J ^a,b   Hoppler, Stefan ^b   Wright, Matthew C ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b UNIVERSITY OF ABERDEEN   (United Kingdom)

Author keywords

catenin; C EBP ; GSK3; Liver; Pancreas; Tcf Lef; WNT3a

Indexed keywords

ALBUMIN; AMYLASE; BETA CATENIN; CCAAT ENHANCER BINDING PROTEIN BETA; CYTOCHROME P450 2C11; CYTOCHROME P450 3A1; GLUCOCORTICOID; GLYCOGEN SYNTHASE KINASE 3ALPHA; GLYCOGEN SYNTHASE KINASE 3BETA; QUERCETIN; T CELL FACTOR PROTEIN; TRANSCRIPTION FACTOR SOX17; WNT PROTEIN; WNT3A PROTEIN;

ACINAR CELL; ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; EMBRYO; LIVER CELL; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; PANCREATIC PROGENITOR CELL; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; STEM CELL;

ANIMALS; BETA CATENIN; CELL LINE; CELL TRANSDIFFERENTIATION; CELLS, CULTURED; DOWN-REGULATION; GLUCOCORTICOIDS; HEPATOCYTES; PANCREAS; PHOSPHORYLATION; RATS; SIGNAL TRANSDUCTION; STEM CELLS; WNT PROTEINS;

EID: 77953575574     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.070722     Document Type: Article

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