A Substrate pharmacophore for the human organic cation/carnitine transporter identifies compounds associated with rhabdomyolysis

Molecular Pharmaceutics

Volumn 9, Issue 4, 2012, Pages 905-913

  Ekins, Sean ^a,b   Diao, Lei ^a,c   Polli, James E ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF PHARMACY   (United States)

^b Collaborations in Chemistry ^*  (United States)

^c UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

Author keywords

carnitine; human organic cation carnitine transporter (hOCTN2); pharmacophore; transporters

Indexed keywords

CARNITINE; IPRATROPIUM BROMIDE; MEPYRAMINE; MILDRONATE; ORGANIC CATION TRANSPORTER; SPIRONOLACTONE; VERAPAMIL;

ARTICLE; DATA BASE; HYDROGEN BOND; IN VITRO STUDY; MOLECULAR INTERACTION; PHARMACOPHORE; PRIORITY JOURNAL; RHABDOMYOLYSIS;

COMPUTERS, MOLECULAR; HUMANS; ORGANIC CATION TRANSPORT PROTEINS; PHARMACEUTICAL PREPARATIONS; RHABDOMYOLYSIS;

EID: 84859361240     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp200438v     Document Type: Article

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