Embryonic onset of late replication requires Cdc25 down-regulation

Genes and Development

Volumn 26, Issue 7, 2012, Pages 714-725

  Farrell, Jeffrey A ^a   Shermoen, Antony W ^a   Yuan, Kai ^a   O'Farrell, Patrick H ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Cdc25; Cdk1; DNA replication; Drosophila; Late replication; Midblastula transition

Indexed keywords

CYCLIN DEPENDENT KINASE 1; ISOPROTEIN; MESSENGER RNA; PROTEIN STRING; PROTEIN TWINE; PROTEIN TYROSINE PHOSPHATASE; UNCLASSIFIED DRUG;

ARTICLE; BLASTULA; CELL CYCLE G2 PHASE; CELL CYCLE S PHASE; CONTROLLED STUDY; DOWN REGULATION; DROSOPHILA MELANOGASTER; EMBRYO; EMBRYO DEVELOPMENT; ENZYME ACTIVITY; GENE SEQUENCE; HETEROCHROMATIN; INTERPHASE; MITOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ANIMALS; CDC2 PROTEIN KINASE; CDC25 PHOSPHATASES; DNA; DNA REPLICATION; DOWN-REGULATION; DROSOPHILA MELANOGASTER; GENE EXPRESSION REGULATION, DEVELOPMENTAL; MITOSIS; S PHASE;

EID: 84859359559     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.186429.111     Document Type: Article

References (36)

1. Alphey L, Jimenez J, White-Cooper H, Dawson I, Nurse P, Glover DM. 1992. twine, a cdc25 homolog that functions in the male and female germline of Drosophila. Cell 69: 977-988.
2. Blomberg I, Hoffmann I. 1999. Ectopic expression of Cdc25A accelerates the G(1)/S transition and leads to premature activation of cyclin E- and cyclin A-dependent kinases. Mol Cell Biol 19: 6183-6194.
3. Blumenthal AB, Kriegstein HJ, Hogness DS. 1974. The units of DNA replication in Drosophila melanogaster chromosomes. Cold Spring Harb Symp Quant Biol 38: 205-223.
4. Boos D, Sanchez-Pulido L, Rappas M, Pearl LH, Oliver AW, Ponting CP, Diffley JFX. 2011. Regulation of DNA replication through Sld3-Dpb11 interaction is conserved from yeast to humans. Curr Biol 21: 1152-1157.
5. Clarkson M, Saint R. 1999. A His2AvDGFP fusion gene complements a lethal His2AvD mutant allele and provides an in vivo marker for Drosophila chromosome behavior. DNA Cell Biol 18: 457-462.
6. Coudreuse D, Nurse P. 2010. Driving the cell cycle with a minimal CDK control network. Nature 468: 1074-1079.
7. Courtot C, Fankhauser C, Simanis V, Lehner CF. 1992. The Drosophila cdc25 homolog twine is required for meiosis. Development 116: 405-416.
8. Edgar BA, Datar SA. 1996. Zygotic degradation of two maternal Cdc25 mRNAs terminates Drosophila's early cell cycle program. Genes Dev 10: 1966-1977.
9. Edgar BA, O'Farrell PH. 1989. Genetic control of cell division patterns in the Drosophila embryo. Cell 57: 177-187.
10. Edgar BA, O'Farrell PH. 1990. The three postblastoderm cell cycles of Drosophila embryogenesis are regulated in G2 by string. Cell 62: 469-480.
11. Edgar BA, Schubiger G. 1986. Parameters controlling transcriptional activation during early Drosophila development. Cell 44: 871-877.
12. Edgar BA, Kiehle CP, Schubiger G. 1986. Cell cycle control by the nucleo-cytoplasmic ratio in early Drosophila development. Cell 44: 365-372.
13. Edgar BA, Sprenger F, Duronio RJ, Leopold P, O'Farrell PH. 1994. Distinct molecular mechanism regulate cell cycle timing at successive stages of Drosophila embryogenesis. Genes Dev 8: 440-452.
14. Foe VE. 1989. Mitotic domains reveal early commitment of cells in Drosophila embryos. Development 107: 1-22.
15. Foe VE, Alberts BM. 1983. Studies of nuclear and cytoplasmic behaviour during the five mitotic cycles that precede gastrulation in Drosophila embryogenesis. J Cell Sci 61: 31-70.
16. Gawlinśki P, Nikolay R, Goursot C, Lawo S, Chaurasia B, Herz H-M, Kussler-Schneider Y, Ruppert T, Mayer M, Grosshans J. 2007. The Drosophila mitotic inhibitor Frühstart specifically binds to the hydrophobic patch of cyclins. EMBO Rep 8: 490-496.
17. Gilbert DM, Takebayashi S-I, Ryba T, Lu J, Pope BD, Wilson KA, Hiratani I. 2010. Space and time in the nucleus: Developmental control of replication timing and chromosome architecture. Cold Spring Harb Symp Quant Biol 75: 143-153.
18. Grosshans J, Wieschaus E. 2000. A genetic link between morphogenesis and cell division during formation of the ventral furrow in Drosophila. Cell 101: 523-531.
19. Grosshans J, Müller HAJ, Wieschaus E. 2003. Control of cleavage cycles in Drosophila embryos by frü hstart. Dev Cell 5: 285-294.
20. Heald R, McLoughlin M, McKeon F. 1993. Human wee1 maintains mitotic timing by protecting the nucleus from cytoplasmically activated Cdc2 kinase. Cell 74: 463-474.
21. Jeffrey PD, Russo AA, Polyak K, Gibbs E, Hurwitz J, Massagué J, Pavletich NP. 1995. Mechanism of CDK activation revealed by the structure of a cyclinA-CDK2 complex. Nature 376: 313-320.
22. Labib K. 2010. How do Cdc7 and cyclin-dependent kinases trigger the initiation of chromosome replication in eukaryotic cells? Genes Dev 24: 1208-1219.
23. Lopez-Mosqueda J, Maas NL, Jonsson ZO, Defazio-Eli LG, Wohlschlegel J, Toczyski DP. 2010. Damage-induced phosphorylation of Sld3 is important to block late origin firing. Nature 467: 479-483.
24. McCleland ML, O'Farrell PH. 2008. RNAi of mitotic cyclins in Drosophila uncouples the nuclear and centrosome cycle. Curr Biol 18: 245-254.
25. McCleland ML, Shermoen AW, O'Farrell PH. 2009. DNA replication times the cell cycle and contributes to the mid-blastula transition in Drosophila embryos. J Cell Biol 187: 7-14.
26. Nurse P. 1990. Universal control mechanism regulating onset of M-phase. Nature 344: 503-508.
27. Papoulas O, Monzo KF, Cantin GT, Ruse C, Yates JR, Ryu YH, Sisson JC. 2010. dFMRP and Caprin, translational regulators of synaptic plasticity, control the cell cycle at the Drosophila mid-blastula transition. Development 137: 4201-4209.
28. Royou A, McCusker D, Kellogg DR, Sullivan W. 2008. Grapes(Chk1) prevents nuclear CDK1 activation by delaying cyclin B nuclear accumulation. J Cell Biol 183: 63-75.
29. Santamaría D, Barrière C, Cerqueira A, Hunt S, Tardy C, Newton K, Céceres JF, Dubus P, Malumbres M, Barbacid M. 2007. Cdk1 is sufficient to drive the mammalian cell cycle. Nature 448: 811-815.
30. Shermoen AW, McCleland ML, O'Farrell PH. 2010. Developmental control of late replication and S phase length. Curr Biol 20: 2067-2077.
31. Sibon OC, Stevenson VA, Theurkauf WE. 1997. DNA-replication checkpoint control at the Drosophila midblastula transition. Nature 388: 93-97.
32. Spadari S, Sala F. 1982. Aphidicolin: A specific inhibitor of nuclear DNA replication in eukaryotes. Trends Biochem Sci 7: 29-32.
33. Thomson AM, Gillespie PJ, Blow JJ. 2010. Replication factory activation can be decoupled from the replication timing program by modulating Cdk levels. J Cell Biol 188: 209-221.
34. Walter J, Newport JW. 1997. Regulation of replicon size in Xenopus egg extracts. Science 275: 993-995.
35. Wilkie GS, Shermoen AW, O'Farrell PH, Davis I. 1999. Transcribed genes are localized according to chromosomal position within polarized Drosophila embryonic nuclei. Curr Biol 9: 1263-1266.
36. Zegerman P, Diffley JFX. 2007. Phosphorylation of Sld2 and Sld3 by cyclin-dependent kinases promotes DNA replication in budding yeast. Nature 445: 281-285.