Calciphylaxis in CKD and beyond

Nephrology Dialysis Transplantation

Volumn 27, Issue 4, 2012, Pages 1314-1318

  Brandenburg, Vincent M ^a   Kramann, Rafael ^a   Specht, Paula ^a   Ketteler, Markus ^b  

^a UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

^b KLINIKUM COBURG   (Germany)

Author keywords

calciphylaxis; parathyroid hormone; sodium thiosulphate; vitamin K; warfarin

Indexed keywords

ANTIVITAMIN K; BISPHOSPHONIC ACID DERIVATIVE; CALCIMIMETIC AGENT; COLLAGEN TYPE 1; FARNOQUINONE; FETUIN A; FIBRONECTIN; PARATHYROID HORMONE; PLACEBO; SCLEROPROTEIN; SODIUM THIOSULFATE; WARFARIN;

ARTICLE; CALCIFIC UREMIC ARTERIOLOPATHY; CALCINOSIS; CHRONIC KIDNEY DISEASE; DISEASE ASSOCIATION; DOWN REGULATION; FETUIN A DEFICIENCY; HUMAN; HYPERBARIC OXYGEN; HYPERPARATHYROIDISM; HYPOALBUMINEMIA; INCIDENCE; KIDNEY BIOPSY; KIDNEY CALCIFICATION; KIDNEY FAILURE; MALNUTRITION; NONHUMAN; PARATHYROIDECTOMY; PATHOPHYSIOLOGY; PREVALENCE; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; RISK ASSESSMENT; RISK BENEFIT ANALYSIS; UPREGULATION; VITAMIN K METABOLISM; VITAMIN SUPPLEMENTATION;

ANTICOAGULANTS; CALCIPHYLAXIS; FEMALE; HUMANS; KIDNEY FAILURE, CHRONIC; MALE; RENAL DIALYSIS; SERUM ALBUMIN; WARFARIN;

EID: 84859358812     PISSN: 09310509     EISSN: 14602385     Source Type: Journal    
DOI: 10.1093/ndt/gfs015     Document Type: Article

References (20)

1. Selye H, Grasso G, Dieudonne J. On the role of adjuvants in calciphylaxis. Rev Allergy 1961; 15: 461-465
2. Hafner J, Keusch G, Wahl C et al. Uremic small-artery disease with medial calcification and intimal hyperplasia (so-called calciphylaxis): a complication of chronic renal failure and benefit from parathyroidectomy. J Am Acad Dermatol 1995; 33: 954-962
3. Brandenburg VM, Cozzolino M, Ketteler M. Calciphylaxis: a still unmet challenge. J Nephrol 2011; 24: 142-148
4. Gipstein RM, Coburn JW, Adams DA et al. Calciphylaxis in man. A syndrome of tissue necrosis and vascular calcification in 11 patients with chronic renal failure. Arch Intern Med 1976; 136: 1273-1280
5. Ng AT, Peng DH. Calciphylaxis. Dermatol Ther 2011; 24: 256-262
6. Hayashi M, Takamatsu I, Kanno Y et al. A case-control study of calciphylaxis in Japanese end-stage renal disease patients. Nephrol Dial Transplant 2012; in press.
7. Angelis M, Wong LL, Myers SA et al. Calciphylaxis in patients on hemodialysis: a prevalence study. Surgery 1997; 122: 1083-1089
8. Brandenburg VM, Schmitz S, Floege J et al. A call for interdisciplinary cooperation. Hautarzt 2011; 62: 452-458
9. Latus J, Kimmel M, Ott G et al. Early stages of calciphylaxis: are skin biopsies the answer? Case Rep Dermatol 2011; 3: 201-205
10. Schurgers LJ, Spronk HM, Soute BA et al. Regression of warfarininduced medial elastocalcinosis by high intake of vitamin K in rats. Blood 2007; 109: 2823-2831 (Pubitemid 46482077)
11. Weijs B, Blaauw Y, Rennenberg RJ et al. Patients using vitamin K antagonists show increased levels of coronary calcification: an observational study in low-risk atrial fibrillation patients. Eur Heart J 2011; 32: 2555-2562
12. Krueger T, Westenfeld R, Schurgers L et al. Coagulation meets calcification: the vitamin K system. Int J Artif Organs 2009; 32: 67-74
13. Jahnen-Dechent W, Heiss A, Schafer C et al. Fetuin-A regulation of calcified matrix metabolism. Circ Res 2011; 108: 1494-1509
14. Westenfeld R, Krueger T, Schlieper G et al. Effect of vitamin K(2) supplementation on functional vitamin K deficiency in hemodialysis patients: a randomized trial. Am J Kidney Dis 2012; 59: 186-195
15. Schlieper G, Brandenburg V, Ketteler M et al. Sodium thiosulfate in the treatment of calcific uremic arteriolopathy. Nat Rev Nephrol 2009; 5: 539-543
16. Cicone JS, Petronis JB, Embert CD et al. Successful treatment of calciphylaxis with intravenous sodium thiosulfate. Am J Kidney Dis 2004; 43: 1104-1108 (Pubitemid 38691507)
17. O'Neill WC, Hardcastle KI. The chemistry of thiosulfate and vascular calcification. Nephrol Dial Transplant 2012; in press.
18. Bair B, Fivenson D. A novel treatment for ulcerative calcinosis cutis. J Drugs Dermatol 2011; 10: 1042-1044
19. O'Neill WC, Lomashvili KA. Recent progress in the treatment of vascular calcification. Kidney Int 2010; 78: 1232-1239
20. Baldwin C, FarahM, Leung M et al. Multi-intervention management of calciphylaxis: a report of 7 cases. Am J Kidney Dis 2011; 58: 988-991