Comparison of the microbiological efficacy of hydrogen peroxide vapor and ultraviolet light processes for room decontamination

Infection Control and Hospital Epidemiology

Volumn 33, Issue 5, 2012, Pages 507-512

  Havill, Nancy L ^a   Moore, Brent A ^b   Boyce, John M ^a,b  

^a HOSPITAL OF SAINT RAPHAEL   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HYDROGEN PEROXIDE;

ARTICLE; BACTERIAL GROWTH; BACTERIAL SPORE; BACTERICIDAL ACTIVITY; BACTERIUM CONTAMINATION; CLOSTRIDIUM DIFFICILE; CONTROLLED STUDY; DISINFECTION; GEOBACILLUS STEAROTHERMOPHILUS; INTERMETHOD COMPARISON; NONHUMAN; OBSERVATIONAL STUDY; PROSPECTIVE STUDY; TEACHING HOSPITAL; ULTRAVIOLET RADIATION; VAPOR;

AEROSOLS; CONNECTICUT; DECONTAMINATION; HOSPITALS, TEACHING; HUMANS; HYDROGEN PEROXIDE; PATIENTS' ROOMS; PROSPECTIVE STUDIES; SPORES, BACTERIAL; ULTRAVIOLET RAYS;

EID: 84859357879     PISSN: 0899823X     EISSN: None     Source Type: Journal    
DOI: 10.1086/665326     Document Type: Article

References (28)

1. Otter JA, Yezli S, French GL. The role played by contaminated surfaces in the transmission of nosocomial pathogens. Infect Control Hosp Epidemiol 2011;32:687-699.
2. Datta R, Platt R, Yokoe DS, Huang SS. Environmental cleaning intervention and risk of acquiring multidrug-resistant organisms from prior room occupants. Arch Intern Med 2011;171:491-494.
3. Nseir S, Blazejewski C, Lubret R, Wallet F, Courcol R, Durocher A. Risk of acquiring multidrug-resistant gram-negative bacilli from prior room occupants in the ICU. Clin Microbiol Infect 2011;17:1201-1208.
4. Drees M, Snydman D, Schmid C, et al. Prior environmental contamination increases the risk of acquisition of vancomycinresistant enterococci. Clin Infect Dis 2008;46:678-685.
5. Shaughnessy MK, Micielli RL, DePestel DD, et al. Evaluation of hospital room assignment and acquisition of Clostridium difficile infection. Infect Control Hosp Epidemiol 2011;32:201-206.
6. Huang SS, Datta R, Platt R. Risk of acquiring antibiotic-resistant bacteria from prior room occupants. Arch Intern Med 2006;166: 1945-1951.
7. Boyce JM, Havill NL, Lipka A, Havill H, Rizvani R. Variations in hospital daily cleaning practices. Infect Control Hosp Epidemiol 2010;31:99-101.
8. Carling PC, Parry MM, Rupp ME, Po JL, Dick B, Von Beheren S. Improving cleaning of the environment surrounding patients in 36 acute care hospitals. Infect Control Hosp Epidemiol 2008; 29:1035-1041.
9. Rutala WA, Weber DJ. Are room decontamination units needed to prevent transmission of environmental pathogens? Infect Control Hosp Epidemiol 2011;32:743-747.
10. Boyce JM. New approaches to decontamination of rooms after patients are discharged. Infect Control Hosp Epidemiol 2009;30: 515-517.
11. Otter JA, Cummins M, Ahmad F, van Tonder C, Drabu YJ. Assessing the biological efficacy and rate of recontamination following hydrogen peroxide vapour decontamination. J Hosp Infect 2007;67:182-188.
12. Otter JA, French GL. Survival of nosocomial bacteria and spores on surfaces and inactivation by hydrogen peroxide vapor. J Clin Microbiol 2009;47:205-207.
13. Jeanes A, Rao G, Osman M, Merrick P. Eradication of persistent environmental MRSA. J Hosp Infect 2005;61:85-86.
14. Otter JA, Yezli S, Schouten MA, van Zanten AR, Houmes-Zielman G, Nohlmans-Paulssen MK. Hydrogen peroxide vapor decontamination of an intensive care unit to remove environmental reservoirs of multidrug-resistant gram-negative rods during an outbreak. Am J Infect Control 2010;38:754-756.
15. Manian FA, Griesenauer S, Senkel D. Impact of an intensive terminal cleaning and disinfection (C/D) protocol involving selected hospital rooms on endemic nosocomial infection (NI) rates of common pathogens at a tertiary care medical center. In: 5th Decennial Meeting of the Society for Healthcare Epidemiology of America (SHEA). Atlanta, GA, 2010. Abstract LB6.
16. Passaretti CL, Otter JA, Lipsett P, et al. Adherence to hydrogen peroxide vapor (HPV) decontamination reduces VRE acquisition in high-risk units. In: 48th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) and the Infectious Diseases Society of America (IDSA). Washington, DC, 2008. Abstract K4124b.
17. Boyce JM, Havill NL, Otter JA, et al. Impact of hydrogen peroxide vapor room decontamination on Clostridium difficile en vironmental contamination and transmission in a healthcare setting. Infect Control Hosp Epidemiol 2008;29:723-729.
18. Rutala WA, Gergen MF, Weber DJ. Room decontamination with UV radiation. Infect Control Hosp Epidemiol 2010;31:1025-1029.
19. Nerandzic MM, Cadnum JL, Pultz MJ, Donskey CJ. Evaluation of an automated ultraviolet radiation device for decontamination of Clostridium difficile and other healthcare-associated pathogens in hospital rooms. BMC Infect Dis 2010;10:197.
20. Boyce JM, Havill NL, Moore BA. Terminal decontamination of patient rooms using an automated mobile UV light unit. Infect Control Hosp Epidemiol 2011;32:737-742.
21. French GL, Otter JA, Shannon KP, Adams NM, Watling D, Parks MJ. Tackling contamination of the hospital environment by methicillin-resistant Staphylococcus aureus (MRSA): a comparison between conventional terminal cleaning and hydrogen peroxide vapour decontamination. J Hosp Infect 2004;57:31-37.
22. McDonnell G, Russell AD. Antiseptics and disinfectants: activity, action, and resistance. Clin Microbiol Rev 1999;12:147-179.
23. Hall L, Otter JA, Chewins J, Wengenack NL. Use of hydrogen peroxide vapor for deactivation of Mycobacterium tuberculosis in a biological safety cabinet and a room. Journal of Clinical Microbiology 2007;45:810-815.
24. Hayden MK, Bonten MJ, Blom DW, Lyle EA, van de Vijver DA, Weinstein RA. Reduction in acquisition of vancomycin-resistant Enterococcus after enforcement of routine environmental cleaning measures. Clin Infect Dis 2006;42:1552-1560.
25. Holmdahl T, Lanbeck P, Wullt M, Walder MH. A head-to-head comparison of hydrogen peroxide vapor and aerosol room decontamination systems. Infect Control Hosp Epidemiol 2011;32: 831-836.
26. Dumigan DG, Boyce JM, Havill NL, Golebiewski M, Balougun O, Rizvani R. Who is caring for your environment of care? developing standardized cleaning procedures and effective monitoring techniques. Am J Infect Control 2010:38(5):387-389.
27. Boyce JM, Havill NL, Dumigan DG, Golebiewski M, Balogun O, Rizvani R. Monitoring the effectiveness of hospital cleaning practices by use of an adenosine triphosphate bioluminescence assay. Infect Control Hosp Epidemiol 2009;30:678-684.
28. Lawley TD, Clare S, Deakin LJ, et al. Use of purified Clostridium difficile spores to facilitate evaluation of health care disinfection regimens. Appl Environ Microbiol 2010;76:6895-6900.