Enhancement of amorphous celecoxib stability by mixing it with octaacetylmaltose: The molecular dynamics study

Molecular Pharmaceutics

Volumn 9, Issue 4, 2012, Pages 894-904

  Grzybowska, K ^a   Paluch, M ^a   Wlodarczyk, P ^a   Grzybowski, A ^a   Kaminski, K ^a   Hawelek, L ^a,b   Zakowiecki, D ^c   Kasprzycka, A ^d   Jankowska Sumara, I ^e  

^a UNIVERSITY OF SILESIA   (Poland)

^b INSTITUTE OF NON FERROUS METALS   (Poland)

^c Pharmaceutical Works Polpharma SA   (Poland)

^d SILESIAN UNIVERSITY OF TECHNOLOGY   (Poland)

^e PEDAGOGICAL UNIVERSITY   (Poland)

Author keywords

amorphous drug; celecoxib; crystallization; devitrification; glass transition; molecular dynamics; octaacetylmaltose; physical stability; secondary relaxations

Indexed keywords

CARBOHYDRATE DERIVATIVE; CELECOXIB; MALTOSE; OCTAACETYLMALTOSE; UNCLASSIFIED DRUG;

ARTICLE; CALCULATION; COOLING; CRYSTALLIZATION; DENSITY FUNCTIONAL THEORY; DIELECTRIC CONSTANT; DRUG MIXTURE; DRUG SOLUBILITY; DRUG STABILITY; DRUG STORAGE; MOLECULAR DYNAMICS; MOLECULAR WEIGHT; PRIORITY JOURNAL; ROOM TEMPERATURE;

DRUG STABILITY; MALTOSE; MOLECULAR DYNAMICS SIMULATION; PYRAZOLES; SULFONAMIDES;

EID: 84859345053     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp200436q     Document Type: Article

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