Sugar coated ceramic nanocarriers for the oral delivery of hydrophobic drugs: Formulation, optimization and evaluation

Drug Development and Industrial Pharmacy

Volumn 38, Issue 5, 2012, Pages 577-586

  Kommineni, Srivani ^a   Ahmad, Samina ^a   Vengala, Pavani ^b   Subramanyam, C V S ^a  

^a Osmania University   (India)

^b JAWAHARLAL NEHRU TECHNOLOGICAL UNIVERSITY   (India)

Author keywords

Aquasomes; hydroxyapatite; lactose; nanoparticles; piroxicam

Indexed keywords

LACTOSE; NANOCARRIER; OLIGOSACCHARIDE; PIROXICAM;

ADSORPTION; ARTICLE; CERAMICS; COATED PARTICLE; COLORIMETRY; DRUG COATING; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG SCREENING; HYDROPHOBICITY; INFRARED SPECTROSCOPY; PRECIPITATION; PROCESS OPTIMIZATION; TRANSMISSION ELECTRON MICROSCOPY; ULTRASOUND;

ANALYSIS OF VARIANCE; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BIOCOMPATIBLE MATERIALS; BIOLOGICAL AVAILABILITY; CERAMICS; DRUG DELIVERY SYSTEMS; DURAPATITE; EXCIPIENTS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; LACTOSE; NANOPARTICLES; PARTICLE SIZE; PIROXICAM; SOLUBILITY; SWEETENING AGENTS;

EID: 84859326924     PISSN: 03639045     EISSN: 15205762     Source Type: Journal    
DOI: 10.3109/03639045.2011.617884     Document Type: Article

References (35)

1. Lipinski C. (2002). Poor aqueous solubility-an industry wide problem in drug discovery. Am Pharm Rev, 5:82-85.
2. Wong SM, Kellaway IW, Murdan S. (2006). Enhancement of the dissolution rate and oral absorption of a poorly water soluble drug by formation of surfactant-containing microparticles. Int J Pharm, 317:61-68. (Pubitemid 43866347)
3. Parikh RK, Manusun SNS, Gohel MC, Soniwala MM. (2005). Dissolution enhancement of nimesulide using complexation and salt formation techniques. Indian Drugs, 42:149-154.
4. Mateja C, Julijana K, Janko K. (2005). Nanoscale polymer carriers to deliver chemotherapeutic agents to tumours. Expert Opin Biol Ther, 5:1557-1569.
5. Tushar RS, Amit A, Sming N. (2006). Mesoporous silica beads embedded with semiconductor quantum dots and iron oxide nanocrystals: dual-function microcarriers for optical encoding and magnetic separation. Anal Chem, 78:5627-5632.
6. Jeong YI, Nah JW, Na HK, Na K, Kim IS, Cho CS et al. (1999). Self-assembling nanospheres of hydrophobized pullulans in water. Drug Dev Ind Pharm, 25:917-927. (Pubitemid 29350273)
7. Jain NK, Jain SK. (2008). Aquasomes as drug carrier. In: Jain NK, ed. Advances in Controlled and Novel Drug Delivery. New Delhi: CBS Publishers, 317-331.
8. Moghimi SM, Hunter AC, Murray JC. (2005). Nanomedicine: current status and future prospects. FASEB J, 19:311-330. (Pubitemid 40316520)
9. Jain SK, Cherian AK, Rana AC (2000). Self-assembled carbohydrate- stabilized ceramic nanoparticles for the parenteral delivery of insulin. Drug Dev Ind Pharm, 26:459-463. (Pubitemid 30207720)
10. Kossovsky N, Millett D, Gelman A, Sponsler E, Hnatyszyn H. (1993). Self-assembling nanostructures. Biotechnology (NY), 11:1534-1536. (Pubitemid 23353693)
11. Umashankar MS, Sachdeva RK, Gulati M. (2010). Aquasomes: a promising carrier for peptides and protein delivery. Nanomedicine, 6:419-426.
12. Kossovsky N, Gelman A, Sponsler EE, Hnatyszyn HJ, Rajguru S, Torres M et al. (1994). Surface-modified nanocrystalline ceramics for drug delivery applications. Biomaterials, 15:1201-1207.
13. Pandey RS, Sahu S, Sudheesh MS, Madan J, Kumar M, Dixit VK. (2011). Carbohydrate modified ultrafine ceramic nanoparticles for allergen immunotherapy. Int Immunopharmacol, 11:925-931.
14. Leung SS, Robinson JR, and Lee VHL (2005). Parenteral products. In: Robinson JR, ed. Controlled Drug Delivery: Fundamentals and Applications. IInd edn, New York: Marcel Dekker, Inc. 462.
15. Kim IS, Kim SH. (2002). Development of a polymeric nanoparticulate drug delivery system. In vitro characterization of nanoparticles based on sugar-containing conjugates. Int J Pharm, 245:67-73.
16. Goyal AK, Khatri K, Mishra N, Mehta A, Vaidya B, Tiwari S et al. (2008). Aquasomes - a nanoparticulate approach for the delivery of antigen. Drug Dev Ind Pharm, 34:1297-1305.
17. Goyal AK, Khatri K, Mishra N, Vaidya B, Tiwari S, Rishi P, Shivani P, Vyas SP. (2009). Development of self-assembled nanoceramic carrier constructs for vaccine delivery. J Biomater Appl, 24:65-84.
18. Martin A. (2002). Physical Pharmacy. 4th Edn. Maryland: Lippincott Williams and Wilkins, pp. 286-288.
19. Cherian AK, Rana AC, Jain SK. (2000). Self-assembled carbohydrate- stabilized ceramic nanoparticles for the parenteral delivery of insulin. Drug Dev Ind Pharm, 26:459-463. (Pubitemid 30207720)
20. Patil S, Pancholi SS, Agrawal S, Agrawal GP. (2004). Surface-modified mesoporous ceramics as delivery vehicle for haemoglobin. Drug Deliv, 11:193-199. (Pubitemid 38720416)
21. Yemm EW, Willis AJ. (1954). The estimation of carbohydrates in plant extracts by anthrone. Biochem J, 57:508-514.
22. Hedge JE, Hofreiter BT. (1962). Determination of reducing sugars and carbohydrates. Analysis and preparation of sugars. In: Whistler RL, Be Miller JN, ed. Carbohydrate Chemistry. New York: Academic Press, 48-59.
23. USP/NF. (2003). The official compendia of standards. Asian ed. Rockville (MD): United States Pharmacopoeial Convention, Inc. 2534, 1486-1487.
24. Kossovsky N, Gelman A, Sponsler EE, Hnatyszyn HJ, Rajguru S, Chow K, Chung A, Torres M, Zemanovich J, Anderson S, Yao G, Wei K, Goodwin C.(1996). Control of molecular polymorphisms by a structured carbohydrate/ceramic delivery vehicle-aquasomes. J Control Rel, 39:383-388. (Pubitemid 26195840)
25. Higuchi T. (1963). Mechanism of sustained-action medication. theoretical analysis of rate of release of solid drugs dispersed in solid matrices. J Pharm Sci, 52:1145-1149.
26. Hixson AW, Crowell JH. (1931). Dependence of reaction velocity upon surface and agitation (I) theoretical consideration. Ind Eng Chem, 23:923-931.
27. Rojas-Oviedo I, Salazar-Lopez RA, Reyes-Gasga J, Quirino-Barreda CT. (2007). Elaboration and structural analysis of aquasomes loaded with indomethacin. Eur J Pharm Sci, 32:223-230. (Pubitemid 47542445)
28. Rawat M, Singh D, Saraf S, Saraf S. (2008). Development and in vitro evaluation of alginate gel-encapsulated, chitosan-coated ceramic nanocores for oral delivery of enzyme. Drug Dev Ind Pharm, 34:181-188. (Pubitemid 351317140)
29. Back JF, Oakenfull D, Smith MB. (1979). Increased thermal stability of proteins in the presence of sugars and polyols. Biochemistry, 18:5191-5196.
30. Kossovsky N, Bunshah RF, Gelman A, Sponsler E, Umarjee DM, Suh TG et al. (1990). A nondenaturing solid phase pharmaceutical carrier comprised of surface-modified nanocrystalline materials. J Appl Biomater, 1:289-294.
31. Kossovsky N, Gelman A, Sponsler E, Millett D. (1991). Nanocrystalline Epstein-Barr virus decoys. J Appl Biomater, 2:251-259.
32. Kossovsky N, Millet D. (1991). Materials biotechnology and blood substitutes. Mater Res Soc Bull Sept, 78-81.
33. Baumann H, Gauldie J. (1994). The acute phase response. Immunol Today, 15:74-80. (Pubitemid 24049800)
34. Kossovsky N, Gelman A, Sponsler E, Rajguru S, Torres M, Mena E et al. (1995). Preservation of surface-dependent properties of viral antigens following immobilization on particulate ceramic delivery vehicles. J Biomed Mater Res, 29:561-573.
35. Sethi P, Sharma A, Patel SN, Singhai AK. (2010). Aquasome - A novel carrier system. IJPLS, 1:222-225.