Amifostine remediates the degenerative effects of radiation on the mineralization capacity of the murine mandible

Plastic and Reconstructive Surgery

Volumn 129, Issue 4, 2012, Pages

  Tchanque Fossuo, Catherine N ^a,b   Donneys, Alexis ^a,b   Deshpande, Sagar S ^a,b   Nelson, Noah S ^a,b   Boguslawski, Matt J ^a,b   Gallagher, K Kelly ^a,b   Sarhaddi, Deniz ^a,b   Poushanchi, Behdod ^a,b   Goldstein, Steven A ^a,b   Buchman, Steven R ^a,b  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMIFOSTINE; RADIOPROTECTIVE AGENT;

ANIMAL; ARTICLE; BONE MINERALIZATION; COMPUTER ASSISTED TOMOGRAPHY; DRUG EFFECT; MALE; MANDIBLE; MICRORADIOGRAPHY; PATHOLOGY; RADIATION DOSE; RADIATION EXPOSURE; RADIATION INJURY; RADIOGRAPHY; RAT; SPRAGUE DAWLEY RAT;

AMIFOSTINE; ANIMALS; CALCIFICATION, PHYSIOLOGIC; MALE; MANDIBLE; MICRORADIOGRAPHY; RADIATION DOSAGE; RADIATION INJURIES, EXPERIMENTAL; RADIATION-PROTECTIVE AGENTS; RATS; RATS, SPRAGUE-DAWLEY; TOMOGRAPHY, X-RAY COMPUTED;

EID: 84859325172     PISSN: 00321052     EISSN: None     Source Type: Journal    
DOI: 10.1097/PRS.0b013e3182454352     Document Type: Article

References (35)

1. Hall EJ. Radiobiology for the Radiologist. 3rd ed. Philadelphia: Lippincott; 1988.
2. Andreassen CN, Grau C, Lindegaard JC. Chemical radioprotection: A critical review of amifostine as a cytoprotector in radiotherapy. Semin Radiat Oncol. 2003;13:62-72.
3. Brizel DM, Wasserman TH, Henke M, et al. Phase III randomized trial of amifostine as a radioprotector in head and neck cancer. J Clin Oncol. 2000;18:3339-3345.
4. Hensley ML, Schuchter LM, Lindley C, et al. American Society of Clinical Oncology clinical practice guidelines for the use of chemotherapy and radiotherapy protectants. J Clin Oncol. 1999;17:3333-3355.
5. Damron TA, Spadaro JA, Margulies B, Damron LA. Dose response of amifostine in protection of growth plate function from irradiation effects. Int J Cancer 2000;90:73-79.
6. Damron TA, Margulies B, Biskup D, Spadaro JA. Amifostine before fractionated irradiation protects bone growth in rats better than fractionation alone. Int J Radiat Oncol Biol Phys. 2001;50:479-483.
7. Damron TA, Spadaro JA, Tamurian RM, Damron LA. Sparing of radiation-induced damage to the physis: Fractionation alone compared to amifostine pretreatment. Int J Radiat Oncol Biol Phys. 2000;47:1067-1071.
8. Monson LA, Farberg AS, Jing XL, Tchanque-Fossuo CN, Donneys A, Buchman SR. Distraction osteogenesis in the rat mandible following radiation and treatment with amifostine. Plast Reconstr Surg. 2010;125:41.
9. Monson LA, Farberg AS. Human equivalent radiation dose response in the rat mandible. Plast Reconstr Surg. 2009;124:2.
10. Zehtabzadeh AJ, Razdolsky ER, Monson LA, et al. Quantitative histomorphometric assessment of regenerate cellularity and bone quality following human equivalent radiation dose response in the rat mandible. Plast Reconstr Surg. 2010;125:43.
11. Tchanque-Fossuo CN, Monson LA, Farberg AS, et al. Doseresponse effect of human equivalent radiation in the murine mandible: Part I. A histomorphometric assessment. Plast Reconstr Surg. 2011;128:114-121.
12. Razdolsky E, Farberg A, Tchanque-Fossuo CN, Monson LA, Donneys A, Buchman SR. Dose response degradation of biomechanical properties of the murine mandible following human equivalent radiation. Plast Reconstr Surg. 2010;125:40.
13. Fregene A, Jing XL, Monson LA, Buchman SR. Alteration in volumetric bone mineralization density gradation patterns in mandibular distraction osteogenesis following radiation therapy. Plast Reconstr Surg. 2009;124:1237-1244.
14. Schwarz DA, Jamali AM, Kakwan MS, Fregene A, Arman KG, Buchman SR. Biomechanical assessment of regenerate integrity in irradiated mandibular distraction osteogenesis. Plast Reconstr Surg. 2009;123(Suppl):114S-122S.
15. Inyang AF, Schwarz DA, Jamali AM, Buchman SR. Quantitative histomorphometric assessment of regenerate cellularity and bone quality in mandibular distraction osteogenesis following radiation therapy. J Craniofac Surg. 2010;21:1438-1442.
16. Schwarz DA, Arman KG, Kakwan MS, Jamali AM, Elmeligy AA, Buchman SR. Regenerate healing outcomes in unilateral mandibular distraction osteogenesis using quantitative histomorphometry. Plast Reconstr Surg. 2010;126:795-805.
17. Nelson NS, Donneys A, Tchanque-Fossuo CN, et al. Normative reference parameters of bone mineral density distribution in the Sprague Dawley rat mandible. Plast Reconstr Surg. 2011;127:61.
18. Marx RE. Osteoradionecrosis: A new concept of its pathophysiology. J Oral Maxillofac Surg. 1983;41:283-288.
19. Marx RE, Johnson RP. Studies in the radiobiology of osteoradionecrosis and their clinical significance. Oral Surg Oral Med Oral Pathol. 1987;64:379-390.
20. Takahashi S, Sugimoto M, Kotoura Y, Sasai K, Oka M, Yamamuro T. Long-term changes in the haversian systems following high-dose irradiation: An ultrastructural and quantitative histomorphological study. J Bone Joint Surg Am. 1994;76:722-738.
21. Mitchell MJ, Logan PM. Radiation-induced changes in bone. Radiographics 1998;18:1125-1136.
22. Vaughan DJ. The influence of bone cells on the formation, and mineralization, of bone matrix. Philos Trans R Soc Lond B Biol Sci. 1984;304:453-454.
23. Seeman E, Delmas PD. Bone quality: The material and structural basis of bone strength and fragility. N Engl J Med. 2006; 354:2250-2261.
24. Boivin G, Meunier PJ. Changes in bone remodeling rate influence the degree of mineralization of bone. Connect Tissue Res. 2002;43:535-537.
25. Boivin G, Farlay D, Bala Y, Doublier A, Meunier PJ, Delmas PD. Influence of remodeling on the mineralization of bone tissue. Osteoporos Int. 2009;20:1023-1026.
26. Ruffonia D, Fratzla P, Roschger P, Klaushofer K, Weinkamer R. The bone mineralization density distribution as a fingerprint of the mineralization process. Bone 2007;40:1308-1319.
27. Meunier PJ, Boivin G. Bone mineral density reflects bone mass but also the degree of mineralization of bone: Therapeutic implications. Bone 1997;21:373-377.
28. Margulies B, Morgan H, Allen M, Strauss J, Spadaro J, Damron T. Transiently increased bone density after irradiation and the radioprotectant drug amifostine in a rat model. Am J Clin Oncol. 2003;26:e106-e114.
29. Verdonck HW, Meijer GJ, Nieman FH, Stoll C, Riediger D, de Baat C. Quantitative computed tomography bone mineral density measurements in irradiated and non-irradiated minipig alveolar bone: An experimental study. Clin Oral Implants Res. 2008;19:465-468.
30. Borah B, Ritman EL, Dufresne TE, et al. The effect of risedronate on bone mineralization as measured by micro-computed tomography with synchrotron radiation: Correlation to histomorphometric indices of turnover. Bone 2005;37:1-9.
31. Podgorsak EB. Radiation Oncology Physics: A Handbook for Teachers and Students. Vienna, Austria: International Atomic Energy Agency; 2003:398-412.
32. Dhakal S, Chen J, McCance S, Rosier R, O'Keefe R, Constine LS. Bone density changes after radiation for extremity arcomas: Exploring the etiology of pathologic fractures. Int J Radiat Oncol Biol Phys. 2011;80:1158-1163.
33. Currey JD. Effects of differences in mineralization on the mechanical properties of bone. Philos Trans R Soc Lond B Biol Sci. 1984;304:509-518.
34. Currey JD. Role of collagen and other organics in the mechanical properties of bone. Osteoporos Int. 2003;14(Suppl): S29-S36.
35. Forrest CR, O'Donovan DA, Yeung I, et al. Efficacy of radioprotection in the prevention of radiation-induced craniofacial bone growth inhibition. Plast Reconstr Surg. 2002;109: 1311-1323; discussion 1324.