"J-wave syndromes" bring the ATP-sensitive potassium channel back in the spotlight

Heart Rhythm

Volumn 9, Issue 4, 2012, Pages 556-557

  Wilde, Arthur A M ^a  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE SENSITIVE POTASSIUM CHANNEL; INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR6.1; INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR6.2; SULFONYLUREA RECEPTOR;

CARDIOMYOPATHY; ELECTROCARDIOGRAPHY; GENETIC SUSCEPTIBILITY; HEART ARRHYTHMIA; HEART REPOLARIZATION; HUMAN; J WAVE SYNDROME; LONG QT SYNDROME; MISSENSE MUTATION; NONHUMAN; NOTE; PRIORITY JOURNAL; ST SEGMENT ELEVATION;

EID: 84859305047     PISSN: 15475271     EISSN: 15563871     Source Type: Journal    
DOI: 10.1016/j.hrthm.2012.01.002     Document Type: Editorial

References (17)

1. M. Haissaguerre, N. Derval, F. Sacher Sudden cardiac arrest associated with early repolarization N Engl J Med 358 2008 2016 2023 (Pubitemid 351681636)
2. H. Barajas-Martínez, D. Hu, T. Ferrer Molecular genetic and functional association of Brugada and early repolarization syndromes with S422L missense mutation in KCNJ8 Heart Rhythm 9 2012 548 555
3. M. Haissaguerre, S. Chatel, F. Sacher Ventricular fibrillation with prominent early repolarization associated with a rare variant of KCNJ8/KATP channel J Cardiovasc Electrophysiol 20 2009 93 98
4. A. Medeiros-Domingo, B.H. Tan, L. Crotti Gain-of-function mutation S422L in the KCNJ8-encoded cardiac K(ATP) channel Kir6.1 as a pathogenic substrate for J-wave syndromes Heart Rhythm 7 2010 1466 1471
5. A.A.M. Wilde, M.J. Ackerman Exercise extreme caution when calling rare genetic variants novel arrhythmia syndrome-susceptibility mutations Heart Rhythm 7 2010 1883 1885
6. S. Kapa, D.J. Tester, B.A. Salisbury Genetic testing for long QT syndromedistinguishing pathogenic mutations from benign variants Circulation 120 2009 1752 1760
7. J.D. Kapplinger, A.P. Landstrom, B.A. Salisbury Distinguishing arrhythmogenic right ventricular cardiomyopathy/dysplasia-associated mutations from background genetic noise J Am Coll Cardiol 57 2011 2317 2327
8. H. Barajas-Martínez, D. Hu, C. Veltmann Novel mutations in the ATP-binding cassette (ABCC8 and ABCC9) transporter genes associated with inherited arrhythmia syndromes Heart Rhythm 8 2011 1825
9. D.J. Tester, B.H. Tan, A. Medeiros-Domingo, C. Song, J.C. Makielsky, M.J. Ackerman Loss-of-function mutations in the KCNJ8-encoded Kir6.1 KATP channel and sudden infant death syndrome Circ Cardiovasc Genet 4 2011 510 515
10. A.A.M. Wilde, M.J. Janse Electrophysiological effects of ATP-sensitive potassium channel modulation: implications for arrhythmogenesis Cardiovasc Res 28 1994 16 24 (Pubitemid 24060342)
11. R.A. Li, M. Leppo, T. Miki, S. Seino, E. Marbn Molecular basis of electrocardiographic ST-segment elevation Circ Res 87 2000 837 839
12. R. Rosso, A. Adler, A. Halkin, S. Viskin Risk of sudden death among young individuals with J waves and early repolarization: putting the evidence into perspective Heart Rhythm 8 2011 923 929
13. S. Viskin, R. Rosso, A. Halkin Making sense of early repolarization Heart Rhythm 2012
14. C. Antzelevitch, G.X. Yan J wave syndromes Heart Rhythm 7 2010 549 558
15. B. Surawicz, P.W. Macfarlane Inappropriate and confusing electrocardiographic terms J-wave syndromes and early repolarization J Am Coll Cardiol 57 2011 1584 1586
16. A.A.M. Wilde, P.G. Postema, J.M. Diego The pathophysiological mechanism underlying Brugada syndrome: depolarization versus repolarization [Point/Counterpoint] J Mol Cell Cardiol 49 2010 543 553
17. M.G. Hoogendijk, T. Opthof, P.G. Postema, A.A. Wilde, J.M. de Bakker, R. Coronel The Brugada ECG pattern: a marker of channelopathy, structural heart disease or neither? Towards a unifying mechanism of the Brugada syndrome Circ Arrhythm Electrophysiol 3 2010 283 290