Self-entanglement of long linear DNA vectors using transient non-B-DNA attachment points: A new concept for improvement of non-viral therapeutic gene delivery

Medical Hypotheses

Volumn 78, Issue 5, 2012, Pages 632-635

  Tolmachov, Oleg E ^a  

^a NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DNA TOPOISOMERASE (ATP HYDROLYSING); DOUBLE STRANDED DNA; GOLD; NAKED DNA; PHOSPHATE; TUNGSTEN;

ADSORPTION; AEROSOL; ARTICLE; CELL NUCLEUS; CHROMATIN STRUCTURE; COVALENT BOND; CYSTIC FIBROSIS; DNA SUPERCOILING; DNA VECTOR; DUCHENNE MUSCULAR DYSTROPHY; ELECTROPORATION; ENHANCER REGION; GENE EXPRESSION; HUMAN; INHALATION; INTRON; MELANOMA; MOLECULAR WEIGHT; NONVIRAL GENE DELIVERY SYSTEM; SHEAR STRESS; TARGET CELL; TECHNOLOGY; TRANSGENE;

BINDING SITES; DNA, B-FORM; GENE THERAPY; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; HUMANS; MODELS, GENETIC; MOLECULAR WEIGHT; NUCLEIC ACID CONFORMATION;

EID: 84859270152     PISSN: 03069877     EISSN: 15322777     Source Type: Journal    
DOI: 10.1016/j.mehy.2012.01.042     Document Type: Article

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