Genetic selection of embryos that later develop the metabolic syndrome

Medical Hypotheses

Volumn 78, Issue 5, 2012, Pages 621-625

  Edwards, M J ^a  

^a UNIVERSITY OF WESTERN SYDNEY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; DECIDUA; EMBRYO; EMBRYO GROWTH; EPIGENETICS; GENETIC SELECTION; GENETIC SUSCEPTIBILITY; GENOME IMPRINTING; GENOTYPE; HUMAN; HYPERTENSION; INTRAUTERINE GROWTH RETARDATION; MALNUTRITION; METABOLIC SYNDROME X; MICROARRAY ANALYSIS; MORTALITY; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; PERINATAL PERIOD; PLACENTA INSUFFICIENCY; PREGNANT WOMAN; PROGENY; SINGLE NUCLEOTIDE POLYMORPHISM;

ANIMALS; EPIGENESIS, GENETIC; FEMALE; FETAL GROWTH RETARDATION; FETAL NUTRITION DISORDERS; HUMANS; MALE; METABOLIC SYNDROME X; MODELS, GENETIC; PLACENTAL INSUFFICIENCY; POLYMORPHISM, SINGLE NUCLEOTIDE; PREGNANCY; SELECTION, GENETIC;

ANIMALIA;

EID: 84859268491     PISSN: 03069877     EISSN: 15322777     Source Type: Journal    
DOI: 10.1016/j.mehy.2012.01.040     Document Type: Article

References (47)

1. Hales C.N., Barker D.J. Type 2 (non-insulin-dependent) diabetes mellitus: the thrifty phenotype hypothesis. Diabetologia 1992, 35(7):595-601.
2. Neel J.V. Diabetes mellitus: a " thrifty" genotype rendered detrimental by " progress" ?. Am J Hum Genet 1962, 14:353-362.
3. Varga O., Harangi M., Olsson I.A., Hansen A.K. Contribution of animal models to the understanding of the metabolic syndrome: a systematic overview. Obes Rev 2010, 11(11):792-807.
4. Hart N. Famine, maternal nutrition and infant mortality: a re-examination of the Dutch hunger winter. Popul Stud (Camb) 1993, 47(1):27-46.
5. Speakman J.R. Thrifty genes for obesity, an attractive but flawed idea, and an alternative perspective: the 'drifty gene' hypothesis. Int J Obes (Lond) 2008, 32(11):1611-1617.
6. Stoger R. The thrifty epigenotype: an acquired and heritable predisposition for obesity and diabetes?. Bioessays 2008, 30(2):156-166.
7. Eriksson J.G., Lindi V., Uusitupa M., Forsen T.J., Laakso M., Osmond C., et al. The effects of the Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-gamma2 gene on insulin sensitivity and insulin metabolism interact with size at birth. Diabetes 2002, 51(7):2321-2324.
8. Fernandez-Twinn D.S., Ozanne S.E. Mechanisms by which poor early growth programs type-2 diabetes, obesity and the metabolic syndrome. Physiol Behav 2006, 88(3):234-243.
9. Armitage J.A., Khan I.Y., Taylor P.D., Nathanielsz P.W., Poston L. Developmental programming of the metabolic syndrome by maternal nutritional imbalance. how strong is the evidence from experimental models in mammals?. J Physiol 2004, 561(Pt. 2):355-377.
10. Godfrey K.M., Sheppard A., Gluckman P.D., Lillycrop K.A., Burdge G.C., McLean C., et al. Epigenetic gene promoter methylation at birth is associated with child's later adiposity. Diabetes 2011, 60(5):1528-1534.
11. Rakyan V.K., Chong S., Champ M.E., Cuthbert P.C., Morgan H.D., Luu K.V., et al. Transgenerational inheritance of epigenetic states at the murine Axin(Fu] allele occurs after maternal and paternal transmission. Proc Natl Acad Sci USA 2003, 100(5):2538-2543.
12. Morgan H.D., Sutherland H.G., Martin D.I., Whitelaw E. Epigenetic inheritance at the agouti locus in the mouse. Nat Genet 1999, 23(3):314-318.
13. Bygren L.O., Kaati G., Edvinsson S. Longevity determined by paternal ancestors' nutrition during their slow growth period. Acta Biotheor 2001, 49(1):53-59.
14. Bygren L.O., Edvinsson S., Brostrom G. Change in food availability during pregnancy: Is it related to adult sudden death from cerebro- and cardiovascular disease in offspring?. Am J Hum Biol 2000, 12(4):447-453.
15. Kaati G., Bygren L.O., Edvinsson S. Cardiovascular and diabetes mortality determined by nutrition during parents' and grandparents' slow growth period. Eur J Hum Genet 2002, 10(11):682-688.
16. Pembrey M.E., Bygren L.O., Kaati G., Edvinsson S., Northstone K., Sjostrom M., et al. Sex-specific, male-line transgenerational responses in humans. Eur J Hum Genet 2006, 14(2):159-166.
17. Weaver I.C., Cervoni N., Champagne F.A., D'Alessio A.C., Sharma S., Seckl J.R., et al. Epigenetic programming by maternal behavior. Nat Neurosci 2004, 7(8):847-884.
18. Wells J.C. The thrifty phenotype: An adaptation in growth or metabolism?. Am J Hum Biol 2011, 23(1):65-75.
19. Singhal A., Lucas A. Early origins of cardiovascular disease: is there a unifying hypothesis?. Lancet 2004, 363(9421):1642-1645.
20. Prentice A.M., Hennig B.J., Fulford A.J. Evolutionary origins of the obesity epidemic: natural selection of thrifty genes or genetic drift following predation release?. Int J Obes (Lond) 2008, 32(11):1607-1610.
21. Hattersley A.T., Beards F., Ballantyne E., Appleton M., Harvey R., Ellard S. Mutations in the glucokinase gene of the fetus result in reduced birth weight. Nat Genet 1998, 19(3):268-270.
22. St Clair D., Xu M., Wang P., Yu Y., Fang Y., Zhang F. Rates of adult schizophrenia following prenatal exposure to the Chinese famine of 1959-1961. JAMA 2005, 294(5):557-562.
23. Stein Z. Famine and Human Development: the Dutch Hunger Winter of Oxford: Oxford University Press; 1975. 1944-5.
24. Deanesly R. Termination of early pregnancy in rats after ovariectomy is due to immediate collapse of the progesterone-dependent decidua. J Reprod Fertil 1973, 35(1):183-186.
25. Kammerer U., Schoppet M., McLellan A.D., Kapp M., Huppertz H.I., Kampgen E., et al. Human decidua contains potent immunostimulatory CD83(+) dendritic cells. Am J Pathol 2000, 157(1):159-169.
26. Rocha V.Z., Libby P. Obesity, inflammation, and atherosclerosis. Nat Rev Cardiol 2009, 6(6):399-409.
27. Chandra R.K. Nutrition and immunology: from the clinic to cellular biology and back again. Proc Nutr Soc 1999, 58(3):681-683.
28. Hill L.M., Guzick D., Fries J., Hixson J. Fetal loss rate after ultrasonically documented cardiac activity between 6 and 14weeks, menstrual age. J Clin Ultrasound 1991, 19(4):221-223.
29. Staessen C., Verpoest W., Donoso P., Haentjens P., Van der Elst J., Liebaers I. Preimplantation genetic screening does not improve delivery rate in women under the age of 36 following single-embryo transfer. Hum Reprod 2008, 23(12):2818-2825.
30. Gorelick R. Neo-Lamarckian medicine. Med Hypotheses. 2004, 62(2):299-303.
31. Affymetrix. Genome-Wide Human SNP Array 6.0 for Cytogenetics. Santa Clara: Affymetrix Corporation; 2011 [cited 2011 24 February]; Available from: http://www.affymetrix.com/estore/browse/products.jsp?productId=prod380006&categoryId=35907&productName=Genome-Wide-Human-SNP-Array-6.0-for-Cytogenetics - 1_1.
32. Song Q., Wang S., Zafari A. Genetics of the metabolic syndrome. Hospital physician 2006, 42:51-61.
33. Purvis-Smith S.G., Saville T., Manass S., Yip M.Y., Lam-Po-Tang P.R., Duffy B., et al. Uniparental disomy 15 resulting from " correction" of an initial trisomy 15. Am J Hum Genet 1992, 50(6):1348-1350.
34. Edwards M.J., Wenstrup R.J., Byers P.H., Cohn D.H. Recurrence of lethal osteogenesis imperfecta due to parental mosaicism for a mutation in the COL1A2 gene of type I collagen. The mosaic parent exhibits phenotypic features of a mild form of the disease. Hum Mutat 1992, 1(1):47-54.
35. Prentice A. Surviving famine. Survival: Survival of the Human Race. Cambridge: Cambridge University Press; 2007. p. 146-7.
36. Poulsen P., Vaag A.A., Kyvik K.O., Moller Jensen D., Beck-Nielsen H. Low birth weight is associated with NIDDM in discordant monozygotic and dizygotic twin pairs. Diabetologia 1997, 40(4):439-446.
37. Hall J.G. Twinning: mechanisms and genetic implications. Curr Opin Genet Dev 1996, 6(3):343-347.
38. Zollino M., Orteschi D., Marangi G., De Crescenzo A., Pecile V., Riccio A., et al. A case of Beckwith-Wiedemann syndrome caused by a cryptic 11p15 deletion encompassing the centromeric imprinted domain of the BWS locus. J Med Genet 2010, 47(6):429-432.
39. Bose B., Wilkie R.A., Madlom M., Forsyth J.S., Faed M.J. Wiedemann-Beckwith syndrome in one of monozygotic twins. Arch Dis Child 1985, 60(12):1191-1192.
40. Bo S., Cavallo-Perin P., Scaglione L., Ciccone G., Pagano G. Low birthweight and metabolic abnormalities in twins with increased susceptibility to Type 2 diabetes mellitus. Diabet Med 2000, 17(5):365-370.
41. Hall J.G. Twins and twinning. Am J Med Genet 1996, 61(3):202-204.
42. Hall J.G., Lopez-Rangel E. Embryologic development and monozygotic twinning. Acta Genet Med Gemellol (Roma) 1996, 45(1-2):53-57.
43. Fraga M.F., Ballestar E., Paz M.F., Ropero S., Setien F., Ballestar M.L., et al. Epigenetic differences arise during the lifetime of monozygotic twins. Proc Natl Acad Sci USA 2005, 102(30):10604-10609.
44. Hochberg Z., Feil R., Constancia M., Fraga M., Junien C., Carel J.C., et al. Child health, developmental plasticity, and epigenetic programming. Endocr Rev 2011, 32(2):159-224.
45. Drake A.J., Walker B.R. The intergenerational effects of fetal programming: non-genomic mechanisms for the inheritance of low birth weight and cardiovascular risk. J Endocrinol 2004, 180(1):1-16.
46. Drake A.J., Walker B.R., Seckl J.R. Intergenerational consequences of fetal programming by in utero exposure to glucocorticoids in rats. Am J Physiol Regul Integr Comp Physiol 2005, 288(1):R34-R38.
47. Yazbek S.N., Spiezio S.H., Nadeau J.H., Buchner D.A. Ancestral paternal genotype controls body weight and food intake for multiple generations. Hum Mol Genet 2010, 19(21):4134-4144.