Low birthweight and metabolic abnormalities in twins with increased susceptibility to type 2 diabetes mellitus

Diabetic Medicine

Volumn 17, Issue 5, 2000, Pages 365-370

  Bo, Simona ^a,c   Cavallo Perin, P ^a   Scaglione, L ^a   Ciccone, G ^b   Pagano, G ^a  

^a UNIVERSITY OF TURIN   (Italy)

^b MOLINETTE HOSPITAL   (Italy)

^c UNIVERSITY OF TURIN   (Italy)

Author keywords

Birthweight; Hyperinsulinaemia; Impaired glucose tolerance; Metabolic syndrome; Twins

Indexed keywords

ADULT; ARTICLE; CONTROLLED STUDY; DIZYGOTIC TWINS; FEMALE; GENETIC SUSCEPTIBILITY; HUMAN; HYPERINSULINEMIA; IMPAIRED GLUCOSE TOLERANCE; LOW BIRTH WEIGHT; MAJOR CLINICAL STUDY; MALE; METABOLIC DISORDER; MONOZYGOTIC TWINS; NON INSULIN DEPENDENT DIABETES MELLITUS; ORAL GLUCOSE TOLERANCE TEST; PREDICTION; REGRESSION ANALYSIS; TWIN DISCORDANCE; TWINS;

ADULT; DIABETES MELLITUS, TYPE 2; DISEASE SUSCEPTIBILITY; DISEASES IN TWINS; EMBRYONIC AND FETAL DEVELOPMENT; FEMALE; FETAL GROWTH RETARDATION; GLUCOSE INTOLERANCE; GLUCOSE TOLERANCE TEST; HUMANS; INFANT, LOW BIRTH WEIGHT; INFANT, NEWBORN; INSULIN; LOGISTIC MODELS; MALE; RISK FACTORS; TWINS, DIZYGOTIC; TWINS, MONOZYGOTIC;

EID: 0034045240     PISSN: 07423071     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1464-5491.2000.00288.x     Document Type: Article

References (24)

1. 1 Phipps K, Barker DJ, Hales CN, Fall CH, Osmond C, Clark PM. Fetal growth and impaired glucose tolerance in men and women. Diabetologia 1993; 36: 225-228.
2. 2 Barker DJP, Hales CN, Fall CHD, Osmond C, Phipps K, Clark PMS. Type 2 (non-insulin dependent) diabetes mellitus, hypertension and hyperlipidaemia (syndrome X): relation to reduced fetal growth. Diabetologia 1993; 36: 62-67.
3. 3 Phillips DIW. Insulin resistance as a programmed response to fetal undernutrition. Diabetologia 1996; 39: 1119-1122.
4. 4 Poulsen P, Vaag AA, Kyvik KO, Moller Jensen D, Beck-Nielsen H. Low birth weight is associated with NIDDM in discordant monozygotic and dizygotic twin pairs. Diabetologia 1997; 40: 439-446.
5. 5 Cook JTE, Levy JC, Page RCL, Shaw JAG, Hattersley AT, Turner RC. Association of low birthweight with beta cell function in the adult first degree relatives of non-insulin dependent diabetic subjects. Br Med J 1993; 306: 302-306.
6. 6 Haffner SM, Stern MP, Hazuda HP, Mitchell BD, Patterson JK. Increased insulin concentrations in nondiabetic offspring of diabetic parents. N Engl J Med 1988; 319: 1297-1301.
7. 7 Leslie RDG, Vulkmann HP, Poncher M, Hanning I, Orskov H, Alberti KGMM. Metabolic abnormalities in children of non-insulin dependent diabetics. Br Med J 1986; 293: 840-842.
8. 8 O'Rahilly S, Turner RC, Matthews DR. Impaired pulsatile secretion of insulin in relatives of patients with non-insulindependent diabetes. N Engl J Med 1988; 318: 1225-1230.
9. 9 Vadheim CM, Rottar JI. Genetics of diabetes mellitus. In Alberti KGMM, DeFronzo RA, Keen H, Zimmet P. eds. International Textbook of Diabetes Mellitus. New York: Wiley & Sons, 1992: 31-98.
10. 10 Cederlof R, Friberg L, Johnsson E, Kaij L. Studies on similarity diagnosis in twins with the aid of mailed questionnaires. Acta Gen Stat Med 1961; 11: 338-362.
11. 11 Sarna S, Kaprio J, Sistonen P, Koskenvuo M. Diagnosis of twin zygosity by mailed questionnaire. Hum Hered 1978; 28: 241-254.
12. 12 Sistonen P, Ehnholm C. On the heritability of serum high density lipoprotein in twins. Am J Hum Genet 1980; 32: 1-7.
13. 13 Bo S, Cavallo-Perin P, Scaglione L, Pagano G. Serum glucose, insulin and C-peptide response to oral glucose is not under evident genetic control in twins with parental NIDDM. Nutr Metab Cardiovasc Dis 1997; 7: 321-325.
14. 14 Bo S, Cavallo-Perin P, Scaglione L, Pagano G. Heritability of cardiovascular risk parameters in subjects with increased susceptibility to non-insulin-dependent diabetes mellitus. Acta Diabetol 1997; 34: 280-284.
15. 15 Saltin B, Grimby G. Physiological analysis of middle aged and old former athletes. Comparison with still active athletes of the same ages. Circulation 1968; 38: 1104-1115.
16. 16 WHO Study Group. Diabetes Mellitus (Technical Report Series No. 727). Geneva: World Health Organization, 1985.
17. 17 Zavaroni I, Bonora E, Pagliara M, Dall'Aglio E, Luchetti L, Buonanno G et al. Risk factors for coronary artery disease in healthy persons with hyperinsulinemia and normal glucose tolerance. N Engl J Med 1989; 320: 702-706.
18. 18 Alberti KGMM, Zimmet PZ for the WHO Consultation. Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus. Provisional report of a WHO consultation. Diabetic Med 1998; 15: 539-553.
19. 19 Phillips DIW, Barker DJP, Hales CN, Hirst S, Osmond C. Thinness at birth and insulin resistance in adult life. Diabetologia 1994; 37: 150-154.
20. 20 Phillips DIW. Twin studies in medical research: can they tell us wheather diseases are genetically determined? Lancet 1993; 341: 1008-1009.
21. 21 Hawkes CH. Twin studies in diabetes mellitus. Diabetic Med 1997; 14: 347-352.
22. 22 Hales CN, Barker DJP. Type 2 (non-insulin-dependent) diabetes mellitus: the thrifty phenotype hypothesis. Diabetologia 1992; 35: 595-601.
23. 23 Denbow ML, Fisk NM. The consequence of monochorionic placentation. Baillieres Clin Obstet Gynaecol 1998; 12: 37-51.
24. 24 Gaziano E, Gaziano C, Brandt D. Doppler velocimetry determined redistribution of fetal blood flow: correlation with growth restriction in diamniotic monochorionic and dyzigotic twins. Am J Obstet Gynecol 1998; 178: 1359-1367.