PH-dependent complexation of histamine H1 receptor antagonists and human serum albumin studied by UV resonance raman spectroscopy

Journal of Physical Chemistry B

Volumn 116, Issue 12, 2012, Pages 3808-3815

  Tardioli, Silvia ^a   Buijs, Joost ^a   Gooijer, Cees ^a   Van Der Zwan, Gert ^a  

^a VU UNIVERSITY AMSTERDAM   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BINDING ENERGY; HYDROGEN BONDS; LIGANDS; PH;

AMINOPYRIDINES; BINDING AFFINITIES; BINDING CONSTANT; BINDING POCKETS; BIOLOGICAL SIGNIFICANCE; CONFORMATIONAL CHANGE; HUMAN SERUM ALBUMINS; INDOLE RINGS; INTERNAL HYDROGEN BONDS; INTRAMOLECULAR HYDROGEN; NEUTRAL SPECIES; PH RANGE; PH VALUE; PH-DEPENDENT; PROTONATED; RECEPTOR ANTAGONISTS; SIDE-CHAINS; SOLUTION CONFORMATIONS; SPECTROSCOPIC EVIDENCE; SPECTROSCOPIC PROPERTY; UV ABSORPTION; UV-RESONANCE RAMAN SPECTROSCOPY;

PROTONATION;

EID: 84859243210     PISSN: 15206106     EISSN: 15205207     Source Type: Journal    
DOI: 10.1021/jp206409d     Document Type: Article

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