Challenges of therapeutic delivery using conducting polymers

Therapeutic Delivery

Volumn 3, Issue 4, 2012, Pages 421-427

  Poole Warren, Laura ^a   Goding, Josef ^a   Green, Rylie ^a   Martens, Penny ^a  

^a UNIVERSITY OF NEW SOUTH WALES   (Australia)

Author keywords

conducting hydrogels; conducting polymers; controlled release; drug delivery; electrical stimulation

Indexed keywords

BIOTIN; CARBON NANOTUBE; CONDUCTING POLYMER; DEXAMETHASONE SODIUM PHOSPHATE; NANOMATERIAL; NANOTUBE; NEUROTROPHIN; NEUROTROPHIN 3; NICOTINIC ACID; POLY 3,4 ETHYLENEDIOXYTHIOPHENE; POLYACRYLAMIDE; POLYGLACTIN; POLYMER; POLYPYRROLE; STREPTAVIDIN; UNCLASSIFIED DRUG;

BIOTINYLATION; CONDUCTING HYDROGEL; CONDUCTING POLYMER ELECTRODE; COVALENT BOND; CYCLIC POTENTIOMETRY; DRUG DELIVERY SYSTEM; DRUG RELEASE; ELECTROCHEMICAL ANALYSIS; ELECTROCHEMICAL DEPOSITION; ELECTRODE; ELECTRON TRANSPORT; ELECTROSTIMULATION; HYDROGEL; MOLECULAR SIZE; NANOPORE; NOTE; OXIDATION; POLYMERIZATION; PRIORITY JOURNAL;

EID: 84859240136     PISSN: 20415990     EISSN: 20416008     Source Type: Journal    
DOI: 10.4155/tde.12.19     Document Type: Note

References (30)

1. Green RA, Lovell NH, Wallace GG, Poole-Warren LA. Conducting polymers for neural interfaces: challenges in developing an effective long-term implant. Biomaterials 29(24-25), 3393-3399 (2008).
2. Svirskis D, Travas-Sejdic J, Rodgers A, Garg S. Electrochemically controlled drug delivery based on intrinsically conducting polymers. J. Control. Release 146(1), 6-15 (2010).
3. Thompson BC, Moulton SE, Ding J et al. Optimising the incorporation and release of a neurotrophic factor using conducting polypyrrole. J. Control. Release 116(3), 285-294 (2006). (Pubitemid 44827404)
4. Green RA, Lovell NH, Poole-Warren LA. Impact of co-incorporating laminin peptide dopants and neurotrophic growth factors on conducting polymer properties. Acta Biomater. 6(1), 63-71 (2010).
5. Thompson BC, Richardson RT, Moulton SE et al. Conducting polymers, dual neurotrophins and pulsed electrical stimulation - dramatic effects on neurite outgrowth. J. Control. Release 141(2), 161-167 (2010).
6. Wadhwa R, Lagenaur CF, Cui XT. Electrochemically controlled release of dexamethasone from conducting polymer polypyrrole coated electrode. J. Control. Release 110(3), 531-541 (2006). (Pubitemid 43163443)
7. Mastragostino M, Soddu L. Electrochemical characterization of "n" doped polyheterocyclic conducting polymers - I. Polybithiophene. Electrochim. Acta 35(2), 463-466 (1990).
8. Kontturi K, Pentti P, Sundholm G. Polypyrrole as a model membrane for drug delivery. J. Electroanal. Chem. 453(1-2), 231-238 (1998). (Pubitemid 128411516)
9. Abidian MR, Kim DH, Martin DC. Conducting-polymer nanotubes for controlled drug release. Adv. Mater. 18(4), 405-409 (2006).
10. Geetha S, Rao CRK, Vijayan M, Trivedi DC. Biosensing and drug delivery by polypyrrole. Anal. Chim. Acta 568(1-2), 119-125 (2006). (Pubitemid 43729732)
11. Luo X, Cui XT. Sponge-like nanostructured conducting polymers for electrically controlled drug release. Electrochem. Commun. 11(10), 1956-1959 (2009).
12. Massoumi B, Entezami A. Electrochemically controlled binding and release of dexamethasone from conducting polymer bilayer films. J. Bioact. Compat. Polym. 17(1), 51-62 (2002). (Pubitemid 34522286)
13. Shain W, Spataro L, Dilgen J et al. Controlling cellular reactive responses around neural prosthetic devices using peripheral and local intervention strategies. IEEE Trans. Neural Syst. Rehabil. Eng. 11(2), 186-188 (2003). (Pubitemid 36935055)
14. Green RA, Lovell NH, Poole-Warren LA. Cell attachment functionality of bioactive conducting polymers for neural interfaces. Biomaterials 30(22), 3637-3644 (2009).
15. Schuettler M, Stiess S, King BV, Suaning GJ. Fabrication of implantable microelectrode arrays by laser cutting of silicone rubber and platinum foil. J. Neural Eng. 2(1), S121 (2005).
16. Richardson RT, Wise AK, Thompson BC et al. Polypyrrole-coated electrodes for the delivery of charge and neurotrophins to cochlear neurons. Biomaterials 30(13), 2614-2624 (2009).
17. Collier JH, Camp JP, Hudson TW, Schmidt CE. Synthesis and characterization of polypyrrole-hyaluronic acid composite biomaterials for tissue engineering applications. J. Biomed. Mater. Res. 50(4), 574-584 (2000). (Pubitemid 30225384)
18. Massoumi B, Entezami A. Controlled release of sulfosalicylic acid during electrochemical switching of conducting polymer bilayers. Eur. Polym. J. 37(5), 1015-1020 (2001). (Pubitemid 32875199)
19. Kang G, Borgens RB, Cho Y. Well-ordered porous conductive polypyrrole as a new platform for neural interfaces. Langmuir 27(10), 6179-6184 (2011).
20. Luo X, Cui XT. Electrochemically controlled release based on nanoporous conducting polymers. Electrochem. Commun. 11(2), 402-404 (2009).
21. Green R, Williams C, Lovell N, Poole- Warren L. Novel neural interface for implant electrodes: improving electroactivity of polypyrrole through MWNT incorporation. J. Mater. Sci. Mater. Med. 19(4), 1625-1629 (2008).
22. Xiao Y, Ye X, He L, Che J. New carbon nanotube-conducting polymer composite electrodes for drug delivery applications. Polym. Intl, 61(2), 190-196 (2012).
23. Luo X, Matranga C, Tan S, Alba N, Cui XT. Carbon nanotube nanoreservior for controlled release of anti-inflammatory dexamethasone. Biomaterials 32(26), 6316-6323 (2011).
24. George PM, Lavan DA, Burdick JA, Chen CY, Liang E, Langer R. Electrically controlled drug delivery from biotin-doped conductive polypyrrole. Adv. Mater. 18(5), 577-581 (2006). (Pubitemid 43385775)
25. Green RA, Baek S, Poole-Warren LA, Martens PJ. Conducting polymer-hydrogels for medical electrode applications. Sci. Technol. Adv. Mater. 11(1), 014107 (2010).
26. Lira LM, Barthus R, Torresi S. Conducting polymers and hydrogels for electrochemically controlled drug release devices. ECS Trans. 3(29), 105-114 (2007).
27. Lira LM, Córdoba DE, Torresi SI. Conducting polymer-hydrogel composites for electrochemical release devices: synthesis and characterization of semi-interpenetrating polyaniline-polyacrylamide networks. Electrochem. Commun. 7(7), 717-723 (2005). (Pubitemid 40788991)
28. Green RA, Hassarati RT, Goding JA et al. Conductive hydrogels. Mechanically robust hybrids for use as biomaterials. Macromol. Biosci. doi:10.1002/mabi.201100490 (Epub ahead of print) (2011).
29. Small CJ, Too CO, Wallace GG. Responsive conducting polymer-hydrogel composites. Polym. Gels Netw. 5(3), 251-265 (1997). (Pubitemid 127451757)
30. Barthus RC, Lira LM, Córdoba DE Torresi SI. Conducting polymer-hydrogel blends for electrochemically controlled drug release devices. J. Braz. Chem. Soc. 19(4), 630-636 (2008).