-
1
-
-
70349256226
-
The 2008 revision of the world health organization (who) classification of myeloid neoplasms and acute leukemia: Rationale and important changes
-
This key reference addresses the current diagnostic WHO criteria changes for the diagnosis of MPNs
-
Vardiman JW, Thiele J, Arber DA, et al. The 2008 revision of the world health organization (who) classification of myeloid neoplasms and acute leukemia: Rationale and important changes. Blood 2009;114:937-951. This key reference addresses the current diagnostic WHO criteria changes for the diagnosis of MPNs.
-
(2009)
Blood
, vol.114
, pp. 937-951
-
-
Vardiman, J.W.1
Thiele, J.2
Arber, D.A.3
-
2
-
-
0001639195
-
Some speculations on the myeloproliferative syndromes
-
Dameshek W. Some speculations on the myeloproliferative syndromes. Blood. 1951;6:372-5.
-
(1951)
Blood
, vol.6
, pp. 372-5
-
-
Dameshek, W.1
-
3
-
-
20144363192
-
Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders
-
DOI 10.1016/S0140-6736(05)71142-9
-
Baxter EJ, Scott LM, Campbell PJ, et al. Acquired mutation of thetyrosine kinase JAK2 in human myeloproliferative disorders. Lancet. 2005;365:1054-61. (Pubitemid 40386783)
-
(2005)
Lancet
, vol.365
, Issue.9464
, pp. 1054-1061
-
-
Baxter, E.J.1
Scott, L.M.2
Campbell, P.J.3
East, C.4
Fourouclas, N.5
Swanton, S.6
Vassiliou, G.S.7
Bench, A.J.8
Boyd, E.M.9
Curtin, N.10
Scott, M.A.11
Erber, W.N.12
Avis, T.13
Barthorpe, A.14
Bignell, G.15
Blow, M.16
Brackenbury, L.17
Buck, G.18
Clegg, S.19
Clements, J.20
Cole, J.21
Davies, H.22
Edkins, S.23
Gray, K.24
Gorton, M.25
O'Meara, S.26
Halliday, K.27
Harrison, R.28
Haynes, W.29
Hills, K.30
Hunter, C.31
Jones, D.32
Kosmidou, V.33
Laman, R.34
Lugg, R.35
Parker, A.36
Perry, J.37
Petty, R.38
Small, A.39
Solomon, H.40
Stephens, P.41
Stephens, Y.42
Stevens, C.43
Smith, R.44
Tarpey, P.45
Tofts, C.46
Varian, J.47
West, S.48
Widaa, S.49
Bamford, S.50
Butler, A.51
Dawson, E.52
Dicks, E.53
Edwards, K.54
Forbes, S.55
Greenman, C.56
Hinton, J.57
Menzies, A.58
Raine, K.59
Shepherd, R.60
Teague, J.61
Yates, A.62
Wooster, R.63
Futreal, A.64
Stratton, M.65
Green, A.R.66
more..
-
4
-
-
17844383458
-
A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera
-
DOI 10.1038/nature03546
-
James C, Ugo V, Le Couedic JP, et al. A unique clonal JAK2mutation leading to constitutive signalling causes polycythaemia vera. Nature. 2005;434:1144-8. (Pubitemid 40663494)
-
(2005)
Nature
, vol.434
, Issue.7037
, pp. 1144-1148
-
-
James, C.1
Ugo, V.2
Le Couedic, J.-P.3
Staerk, J.4
Delhommeau, F.5
Lacout, C.6
Garcon, L.7
Raslova, H.8
Berger, R.9
Bennaceur-Griscelli, A.10
Villeval, J.L.11
Constantinescu, S.N.12
Casadevall, N.13
Vainchenker, W.14
-
5
-
-
17644424955
-
A gain-of-function mutation of JAK2 in myeloproliferative disorders
-
DOI 10.1056/NEJMoa051113
-
Kralovics R, Passamonti F, Buser AS, et al. A gain-of-function mutation of JAK2 in myeloproliferative disorders. N Engl J Med. 2005;352:1779-90. (Pubitemid 40570926)
-
(2005)
New England Journal of Medicine
, vol.352
, Issue.17
, pp. 1779-1790
-
-
Kralovics, R.1
Passamonti, F.2
Buser, A.S.3
Teo, S.-S.4
Tiedt, R.5
Passweg, J.R.6
Tichelli, A.7
Cazzola, M.8
Skoda, R.C.9
-
6
-
-
20244369569
-
Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis
-
DOI 10.1016/j.ccr.2005.03.023
-
Levine RL, Wadleigh M, Cools J, et al. Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis. Cancer Cell. 2005;7:387-97. (Pubitemid 40544655)
-
(2005)
Cancer Cell
, vol.7
, Issue.4
, pp. 387-397
-
-
Levine, R.L.1
Wadleigh, M.2
Cools, J.3
Ebert, B.L.4
Wernig, G.5
Huntly, B.J.P.6
Boggon, T.J.7
Wlodarska, I.8
Clark, J.J.9
Moore, S.10
Adelsperger, J.11
Koo, S.12
Lee, J.C.13
Gabriel, S.14
Mercher, T.15
D'Andrea, A.16
Frohling, S.17
Dohner, K.18
Marynen, P.19
Vandenberghe, P.20
Mesa, R.A.21
Tefferi, A.22
Griffin, J.D.23
Eck, M.J.24
Sellers, W.R.25
Meyerson, M.26
Golub, T.R.27
Lee, S.J.28
Gilliland, D.G.29
more..
-
7
-
-
34248364065
-
Primary myelofibrosis (PMF), post polycythemia vera myelofibrosis (post-PV MF), post essential thrombocythemia myelofibrosis (post-ET MF), blast phase PMF (PMF-BP): Consensus on terminology by the international working group for myelofibrosis research and treatment (IWG-MRT)
-
DOI 10.1016/j.leukres.2006.12.002, PII S0145212606004693
-
Mesa RA, Verstovsek S, Cervantes F, et al. Primary myelofibrosis(PMF), post polycythemia vera myelofibrosis (POST-PV MF), post essential thrombocythemia myelofibrosis (POST-ET MF), blast phase pmf (PMF-BP): Consensus on terminology by the International Working Group for Myelofibrosis Research and Treatment (IWG-MRT). Leukemia Res. 2007;31:737-40. (Pubitemid 46855906)
-
(2007)
Leukemia Research
, vol.31
, Issue.6
, pp. 737-740
-
-
Mesa, R.A.1
Verstovsek, S.2
Cervantes, F.3
Barosi, G.4
Reilly, J.T.5
Dupriez, B.6
Levine, R.7
Le Bousse-Kerdiles, M.-C.8
Wadleigh, M.9
Campbell, P.J.10
Silver, R.T.11
Vannucchi, A.M.12
Deeg, H.J.13
Gisslinger, H.14
Thomas, D.15
Odenike, O.16
Solberg, L.A.17
Gotlib, J.18
Hexner, E.19
Nimer, S.D.20
Kantarjian, H.21
Orazi, A.22
Vardiman, J.W.23
Thiele, J.24
Tefferi, A.25
more..
-
8
-
-
12844284481
-
Leukemic transformation in myelofibrosis with myeloid metaplasia: A single-institution experience with 91 cases
-
DOI 10.1182/blood-2004-07-2864
-
Mesa RA, Li CY, Ketterling RP, et al. Leukemic transformation in myelofibrosis with myeloid metaplasia: A single-institution experien ce with 91 cases. Blood. 2005;105:973-7. (Pubitemid 40170863)
-
(2005)
Blood
, vol.105
, Issue.3
, pp. 973-977
-
-
Mesa, R.A.1
Li, C.-Y.2
Ketterling, R.P.3
Schroeder, G.S.4
Knudson, R.A.5
Tefferi, A.6
-
9
-
-
20144389274
-
Acute leukemia in polycythemia vera: An analysis of 1638 patients enrolled in a prospective observational study
-
DOI 10.1182/blood-2004-09-3426
-
Finazzi G, Caruso V, Marchioli R, et al. Acute leukemia in polycythemia vera: an analysis of 1638 patients enrolled in a prospective observational study. Blood. 2005;105:2664-70. (Pubitemid 40446255)
-
(2005)
Blood
, vol.105
, Issue.7
, pp. 2664-2670
-
-
Finazzi, G.1
Caruso, V.2
Marchioli, R.3
Capnist, G.4
Chisesi, T.5
Finelli, C.6
Gugliotta, L.7
Landolfi, R.8
Kutti, J.9
Gisslinger, H.10
Marilus, R.11
Patrono, C.12
Pogliani, E.M.13
Randi, M.L.14
Villegas, A.15
Tognoni, G.16
Barbui, T.17
-
10
-
-
79952075257
-
Myeloproliferative neoplasms: Molecular pathophysiology, essential clinical understanding, and treatment strategies
-
Tefferi A, Vainchenker W. Myeloproliferative neoplasms: molecular pathophysiology, essential clinical understanding, and treatment strategies. J Clin Oncol. 2011;29:573-82.
-
(2011)
J Clin Oncol
, vol.29
, pp. 573-82
-
-
Tefferi, A.1
Vainchenker, W.2
-
11
-
-
0037204953
-
A road map for those who don't know JAK-STAT
-
DOI 10.1126/science.1071545
-
Aaronson DS, Horvath CM. A road map for those who don't know JAK-STAT. Science. 2002;296:1653-5. (Pubitemid 34579157)
-
(2002)
Science
, vol.296
, Issue.5573
, pp. 1653-1655
-
-
Aaronson, D.S.1
Horvath, C.M.2
-
12
-
-
43249084493
-
Ratio of mutant JAK2-V617F to wild-type Jak2 determines the MPD phenotypes in transgenic mice
-
Tiedt R, Hao-Shen H, Sobas MA, et al. Ratio of mutant JAK2-V617F to wild-type Jak2 determines the MPD phenotypes in transgenic mice. Blood. 2008;111:3931-40.
-
(2008)
Blood
, vol.111
, pp. 3931-40
-
-
Tiedt, R.1
Hao-Shen, H.2
Sobas, M.A.3
-
13
-
-
33746054198
-
V617F and leukemic transformation in myelofibrosis with myeloid metaplasia
-
DOI 10.1016/j.leukres.2006.01.008, PII S0145212606000452
-
Mesa RA, Powell H, Lasho T, et al. JAK2(V617F) and leukemic transformation in myelofibrosis with myeloid metaplasia. Leukemia Res. 2006;30:1457-60. (Pubitemid 44307317)
-
(2006)
Leukemia Research
, vol.30
, Issue.11
, pp. 1457-1460
-
-
Mesa, R.A.1
Powell, H.2
Lasho, T.3
DeWald, G.4
McClure, R.5
Tefferi, A.6
-
14
-
-
42449124578
-
Low JAK2V617F allele burden in primary myelofibrosis, compared to either a higher allele burden or unmutated status, is associated with inferior overall and leukemia-free survival
-
DOI 10.1038/sj.leu.2405097, PII 2405097
-
Tefferi A, Lasho TL, Huang J, et al. Low JAK2V617F alleleburden in primary myelofibrosis, compared to either a higher allele burden or unmutated status, is associated with inferior overall and leukemia-free survival. Leukemia. 2008;22:756-61. (Pubitemid 351559282)
-
(2008)
Leukemia
, vol.22
, Issue.4
, pp. 756-761
-
-
Tefferi, A.1
Lasho, T.L.2
Huang, J.3
Finke, C.4
Mesa, R.A.5
Li, C.Y.6
Wu, W.7
Hanson, C.A.8
Pardanani, A.9
-
15
-
-
34347394712
-
Leukemic blasts in transformed JAK2-V617F-positive myeloproliferative disorders are frequently negative for the JAK2-V617F mutation
-
DOI 10.1182/blood-2006-12-062125
-
Theocharides A, Boissinot M, Girodon F, et al. Leukemic blasts in transformed JAK2-V617F-positive myeloproliferative disordersare frequently negative for the JAK2-V617F mutation. Blood.2007;110:375-9. (Pubitemid 47026857)
-
(2007)
Blood
, vol.110
, Issue.1
, pp. 375-379
-
-
Theocharides, A.1
Boissinot, M.2
Girodon, F.3
Garand, R.4
Teo, S.-S.5
Lippert, E.6
Talmant, P.7
Tichelli, A.8
Hermouet, S.9
Skoda, R.C.10
-
16
-
-
84860839426
-
Blast transformation in a patientwith primary myelofibrosis initiated from JAK2 V617F progenitor
-
Swierczek SI, Yoon D, Prchal JT. Blast transformation in a patientwith primary myelofibrosis initiated from JAK2 V617F progenitor. Blood. 2007;110:a4665.
-
(2007)
Blood
, vol.110
-
-
Swierczek, S.I.1
Yoon, D.2
Prchal, J.T.3
-
17
-
-
52649131772
-
The natural history andtreatment outcome of blast phase BCR-ABL-myeloproliferative neoplasms
-
Tam CS, Nussenzveig RM, Popat U, et al. The natural history andtreatment outcome of blast phase BCR-ABL-myeloproliferative neoplasms. Blood. 2008;112:1628-37.
-
(2008)
Blood
, vol.112
, pp. 1628-37
-
-
Tam, C.S.1
Nussenzveig, R.M.2
Popat, U.3
-
18
-
-
79953208053
-
What is the role ofJAK2V617F mutation in leukemic transformation of myeloproliferative neoplasms?
-
Lopes da Silva R, Ribeiro P, Lourenco A, et al. What is the role ofJAK2V617F mutation in leukemic transformation of myeloproliferative neoplasms? Lab Hematol. 2011;17:12-6.
-
(2011)
Lab Hematol
, vol.17
, pp. 12-6
-
-
Lopes Da Silva, R.1
Ribeiro, P.2
Lourenco, A.3
-
19
-
-
77950977381
-
Two routes to leukemic transformation after a JAK2 mutation-positive myeloproliferative neoplasm
-
Beer PA, Delhommeau F, LeCouedic JP, et al. Two routes to leukemic transformation after a JAK2 mutation-positive myeloproliferative neoplasm. Blood. 2010;115:2891-900.
-
(2010)
Blood
, vol.115
, pp. 2891-900
-
-
Beer, P.A.1
Delhommeau, F.2
Lecouedic, J.P.3
-
20
-
-
77950388949
-
Clonal analysis of TET2 and JAK2 mutations suggests that TET2 can be a late event in the progression of myeloproliferative neoplasms
-
Schaub FX, Looser R, Li S, et al. Clonal analysis of TET2 and JAK2 mutations suggests that TET2 can be a late event in the progression of myeloproliferative neoplasms. Blood. 2010;115:2003-7.
-
(2010)
Blood
, vol.115
, pp. 2003-7
-
-
Schaub, F.X.1
Looser, R.2
Li, S.3
-
21
-
-
54049123194
-
Genetic complexity of myeloproliferative neoplasms
-
Kralovics R. Genetic complexity of myeloproliferative neoplasms Leukemia. 2008;22:1841-8.
-
(2008)
Leukemia
, vol.22
, pp. 1841-8
-
-
Kralovics, R.1
-
22
-
-
33846660947
-
JAK2 exon 12 mutations in polycythemia vera and idiopathic erythrocytosis
-
DOI 10.1056/NEJMoa065202
-
Scott LM, Tong W, Levine RL, et al. JAK2 exon 12 mutations in polycythemia vera and idiopathic erythrocytosis. N Engl J Med. 2007;356:459-68. (Pubitemid 46193073)
-
(2007)
New England Journal of Medicine
, vol.356
, Issue.5
, pp. 459-468
-
-
Scott, L.M.1
Tong, W.2
Levine, R.L.3
Scott, M.A.4
Beer, P.A.5
Stratton, M.R.6
Futreal, P.A.7
Erber, W.N.8
McMullin, M.F.9
Harrison, C.N.10
Warren, A.J.11
Gilliland, D.G.12
Lodish, H.F.13
Green, A.R.14
-
23
-
-
38949160429
-
Somatic mutations of JAK2 exon 12 in patients with JAK2 (V617F)-negative myeloproliferative disorders
-
DOI 10.1182/blood-2007-07-101576
-
Pietra D, Li S, Brisci A, et al. Somatic mutations of JAK2 exon 12 in patients with JAK2 (V617F)-negative myeloproliferative disorders. Blood. 2008;111:1686-9. (Pubitemid 351213460)
-
(2008)
Blood
, vol.111
, Issue.3
, pp. 1686-1689
-
-
Pietra, D.1
Li, S.2
Brisci, A.3
Passamonti, F.4
Rumi, E.5
Theocharides, A.6
Ferrari, M.7
Gisslinger, H.8
Kralovics, R.9
Cremonesi, L.10
Skoda, R.11
Cazzola, M.12
-
24
-
-
52249100940
-
A sensitive detection method for MPLW515l or MPLW515K mutation in chronic myeloproliferative disorders with locked nucleic acid-modified probes and real-time polymerase chain reaction
-
Pancrazzi A, Guglielmelli P, Ponziani V, et al. A sensitive detection method for MPLW515l or MPLW515K mutation in chronic myeloproliferative disorders with locked nucleic acid-modified probes and real-time polymerase chain reaction. J Mol Diagn. 2008;10:435-41.
-
(2008)
J Mol Diagn
, vol.10
, pp. 435-41
-
-
Pancrazzi, A.1
Guglielmelli, P.2
Ponziani, V.3
-
25
-
-
33746437130
-
MPLW515l is a novel somatic activating mutation in myelofibrosis with myeloid metaplasia
-
Pikman Y, Lee BH, Mercher T, et al. MPLW515l is a novel somatic activating mutation in myelofibrosis with myeloid metaplasia. PLoS Med. 2006;3:e270.
-
(2006)
PLoS Med
, vol.3
-
-
Pikman, Y.1
Lee, B.H.2
Mercher, T.3
-
26
-
-
66149146320
-
Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1
-
Tahiliani M, Koh KP, Shen Y, et al. Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1. Science. 2009;324:930-5.
-
(2009)
Science
, vol.324
, pp. 930-5
-
-
Tahiliani, M.1
Koh, K.P.2
Shen, Y.3
-
27
-
-
67349124376
-
TET2 mutations and their clinical correlates in polycythemia vera, essential thrombocythemia and myelofibrosis
-
Tefferi A, Pardanani A, Lim KH, et al. TET2 mutations and their clinical correlates in polycythemia vera, essential thrombocythemia and myelofibrosis. Leukemia. 2009;23:905-11.
-
(2009)
Leukemia
, vol.23
, pp. 905-11
-
-
Tefferi, A.1
Pardanani, A.2
Lim, K.H.3
-
28
-
-
70450239681
-
Mutations of ASXL1 gene in myeloproliferative neoplasms
-
Carbuccia N, Murati A, Trouplin V, et al. Mutations of ASXL1 gene in myeloproliferative neoplasms. Leukemia. 2009;23:2183-6.
-
(2009)
Leukemia
, vol.23
, pp. 2183-6
-
-
Carbuccia, N.1
Murati, A.2
Trouplin, V.3
-
29
-
-
77954583280
-
High-density single nucleotidepolymorphism array analysis and ASXL1 gene mutation screening in chronic myeloid leukemia during disease progression
-
Boultwood J, Perry J, Zaman R, et al. High-density single nucleotidepolymorphism array analysis and ASXL1 gene mutation screening in chronic myeloid leukemia during disease progression. Leukemia. 2010;24:1139-45.
-
(2010)
Leukemia
, vol.24
, pp. 1139-45
-
-
Boultwood, J.1
Perry, J.2
Zaman, R.3
-
30
-
-
79957593717
-
CBL, CBLB,TET2, ASXL1, and IDH1/2 mutations and additional chromosomal aberrations constitute molecular events in chronic myelogenous leukemia
-
Makishima H, Jankowska AM, McDevitt MA, et al. CBL, CBLB,TET2, ASXL1, and IDH1/2 mutations and additional chromosomal aberrations constitute molecular events in chronic myelogenous leukemia. Blood. 2011;117(21):e198-206.
-
(2011)
Blood
, vol.117
, Issue.21
-
-
Makishima, H.1
Jankowska, A.M.2
McDevitt, M.A.3
-
31
-
-
79960227474
-
Concomitant analysis of EZH2 and ASXL1 mutations in myelofibrosis, chronic myelomonocytic leukemia and blast-phase myeloproliferative neoplasms
-
Abdel-Wahab O, Pardanani A, Patel J, et al. Concomitant analysis of EZH2 and ASXL1 mutations in myelofibrosis, chronic myelomonocytic leukemia and blast-phase myeloproliferative neoplasms. Leukemia 2011
-
(2011)
Leukemia
-
-
Abdel-Wahab, O.1
Pardanani, A.2
Patel, J.3
-
32
-
-
72049125350
-
Cancer-associated IDH1 mutations produce 2-hydroxyglutarate
-
Dang L, White DW, Gross S, et al. Cancer-associated IDH1 mutations produce 2-hydroxyglutarate. Nature. 2009;462:739-44.
-
(2009)
Nature
, vol.462
, pp. 739-44
-
-
Dang, L.1
White, D.W.2
Gross, S.3
-
33
-
-
77149134353
-
Cancer-associated metabolite 2-hydroxyglutarate accumulates in acute myelogenous leukemia with isocitrate dehydrogenase 1 and 2 mutations
-
Gross S, Cairns RA, Minden MD, et al. Cancer-associated metabolite 2-hydroxyglutarate accumulates in acute myelogenous leukemia with isocitrate dehydrogenase 1 and 2 mutations. J Exp Med. 2010;207:339-44.
-
(2010)
J Exp Med
, vol.207
, pp. 339-44
-
-
Gross, S.1
Cairns, R.A.2
Minden, M.D.3
-
34
-
-
77958021645
-
LNK mutation studies inblast-phase myeloproliferative neoplasms, and in chronic-phase disease with TET2, IDH, JAK2 or MPL mutations
-
Pardanani A, Lasho T, Finke C, et al. LNK mutation studies inblast-phase myeloproliferative neoplasms, and in chronic-phase disease with TET2, IDH, JAK2 or MPL mutations. Leukemia. 2010;24:1713-8.
-
(2010)
Leukemia
, vol.24
, pp. 1713-8
-
-
Pardanani, A.1
Lasho, T.2
Finke, C.3
-
35
-
-
77954661062
-
Deletions of the transcription factor IKAROS in myeloproliferative neoplasms
-
Jager R, Gisslinger H, Passamonti F, et al. Deletions of the transcription factor IKAROS in myeloproliferative neoplasms. Leukemia. 2010;24:1290-8.
-
(2010)
Leukemia
, vol.24
, pp. 1290-8
-
-
Jager, R.1
Gisslinger, H.2
Passamonti, F.3
-
36
-
-
0141498523
-
Contrasting incidence of acute monocytic and granulocyticleukemias in p32-treated patients with polycythemia vera and chronic lymphocytic leukemia
-
Osgood EE. Contrasting incidence of acute monocytic and granulocyticleukemias in p32-treated patients with polycythemia vera and chronic lymphocytic leukemia. J Lab Clin Med. 1964;64:560-73.
-
(1964)
J Lab Clin Med
, vol.64
, pp. 560-73
-
-
Osgood, E.E.1
-
37
-
-
0141996510
-
Use and risks of phosphorus-32 in the treatment of polycythaemia vera
-
DOI 10.1007/s00259-003-1270-6
-
Parmentier C. Use and risks of phosphorus-32 in the treatment of polycythaemia vera. Eur J Nucl Med Mol Imaging. 2003;30:1413-7. (Pubitemid 37247961)
-
(2003)
European Journal of Nuclear Medicine and Molecular Imaging
, vol.30
, Issue.10
, pp. 1413-1417
-
-
Parmentier, C.1
-
38
-
-
20244370678
-
Melphalan treatment in patients with myelofibrosis with myeloid metaplasia
-
DOI 10.1046/j.0007-1048.2001.03331.x
-
Petti MC, Latagliata R, Spadea T, et al. Melphalan treatment in patients with myelofibrosis with myeloid metaplasia. Br J Haematol.2002;116:576-81. (Pubitemid 34178656)
-
(2002)
British Journal of Haematology
, vol.116
, Issue.3
, pp. 576-581
-
-
Petti, M.C.1
Latagliata, R.2
Spadea, T.3
Spadea, A.4
Montefusco, E.5
Aloe Spiriti, M.A.6
Avvisati, G.7
Breccia, M.8
Pescarmona, E.9
Mandelli, F.10
-
39
-
-
33745714754
-
Long-term incidence of hematological evolution in three French prospective studies of hydroxyurea and pipobroman in polycythemia vera and essential thrombocythemia
-
Kiladjian JJ, Rain JD, Bernard JF, et al. Long-term incidence of hematological evolution in three French prospective studies of hydroxyurea and pipobroman in polycythemia vera and essential thrombocythemia. Semin Thromb Hemost. 2006;32:417-21.
-
(2006)
Semin Thromb Hemost
, vol.32
, pp. 417-21
-
-
Kiladjian, J.J.1
Rain, J.D.2
Bernard, J.F.3
-
40
-
-
0030784247
-
Treatment of polycythemia vera: The use of hydroxyurea and pipobroman in 292 patients under the age of 65 years
-
Najean Y, Rain JD. Treatment of polycythemia vera: The use of hydroxyurea and pipobroman in 292 patients under the age of65 years. Blood. 1997;90:3370-7. (Pubitemid 27473405)
-
(1997)
Blood
, vol.90
, Issue.9
, pp. 3370-3377
-
-
Najean, Y.1
Rain, J.-D.2
-
41
-
-
0037414164
-
Effect of Hydroxyurea on Mortality and Morbidity in Adult Sickle Cell Anemia: Risks and Benefits Up to 9 Years of Treatment
-
DOI 10.1001/jama.289.13.1645
-
Steinberg MH, Barton F, Castro O, et al. Effect of hydroxyurea on mortality and morbidity in adult sickle cell anemia: Risks and benefits up to 9 years of treatment. JAMA. 2003;289:1645-51. (Pubitemid 37430269)
-
(2003)
Journal of the American Medical Association
, vol.289
, Issue.13
, pp. 1645-1651
-
-
Steinberg, M.H.1
Barton, F.2
Castro, O.3
Pegelow, C.H.4
Ballas, S.K.5
Kutlar, A.6
Orringer, E.7
Bellevue, R.8
Olivieri, N.9
Eckman, J.10
Varma, M.11
Ramirez, G.12
Adler, B.13
Smith, W.14
Carlos, T.15
Ataga, K.16
DeCastro, L.17
Bigelow, C.18
Saunthararajah, Y.19
Telfer, M.20
Vichinsky, E.21
Claster, S.22
Shurin, S.23
Bridges, K.24
Waclawiw, M.25
Bonds, D.26
Terrin, M.27
more..
-
42
-
-
46049106196
-
Risk factors for leukemic transformation in patients with primary myelofibrosis
-
DOI 10.1002/cncr.23505
-
Huang J, Li CY, Mesa RA, et al. Risk factors for leukemic transformation in patients with primary myelofibrosis. Cancer. 2008;112:2726-32. (Pubitemid 351969217)
-
(2008)
Cancer
, vol.112
, Issue.12
, pp. 2726-2732
-
-
Huang, J.1
Li, C.-Y.2
Mesa, R.A.3
Wu, W.4
Hanson, C.A.5
Pardanani, A.6
Tefferi, A.7
-
43
-
-
18544413070
-
Splenectomy and risk of blast transformation in myelofibrosis with myeloid metaplasia
-
Barosi G, Ambrosetti A, Centra A, et al. Splenectomy and risk of blast transformation in myelofibrosis with myeloid metaplasia. Italian cooperative study group on myeloid with myeloid metaplasia. Blood. 1998;91:3630-6. (Pubitemid 28225729)
-
(1998)
Blood
, vol.91
, Issue.10
, pp. 3630-3636
-
-
Barosi, G.1
Ambrosetti, A.2
Centra, A.3
Falcone, A.4
Finelli, C.5
Foa, P.6
Grossi, A.7
Guarnone, R.8
Rupoli, S.9
Luciano, L.10
Petti, M.C.11
Pogliani, E.12
Russo, D.13
Ruggeri, M.14
Quaglini, S.15
-
44
-
-
33745811661
-
Palliative goals, patient selection, and perioperative platelet management: Outcomes and lessons from 3 decades of splenectomy for myelofibrosis with myeloid metaplasia at the Mayo Clinic
-
DOI 10.1002/cncr.22021
-
Mesa RA, Nagorney DS, Schwager S, et al. Palliative goals, patient selection, and perioperative platelet management: Outcomes and lessons from 3 decades of splenectomy for myelofibrosis with myeloid metaplasia at the Mayo Clinic. Cancer. 2006;107:361-70. (Pubitemid 44036566)
-
(2006)
Cancer
, vol.107
, Issue.2
, pp. 361-370
-
-
Mesa, R.A.1
Nagorney, D.S.2
Schwager, S.3
Allred, J.4
Tefferi, A.5
-
45
-
-
0036008494
-
INK4a in agnogenic myeloid metaplasia (AMM) and AMM in leukaemic transformation
-
DOI 10.1046/j.0007-1048.2001.03319.x
-
Wang JC, Chen W, Nallusamy S, et al. Hypermethylation of the P15INK4b and P16INK4a in agnogenic myeloid metaplasia (AMM) and AMM in leukaemic transformation. Br J Haematol. 2002;116:582-6. (Pubitemid 34178657)
-
(2002)
British Journal of Haematology
, vol.116
, Issue.3
, pp. 582-586
-
-
Wang, J.C.1
Chen, W.2
Nallusamy, S.3
Chen, C.4
Novetsky, A.D.5
-
46
-
-
78149453788
-
Treatment of progression of Philadelphia-negative myeloproliferative neoplasms to myelodysplastic syndrome or acute myeloid leukemia by azacitidine: A report on 54 cases on the behalf of the Groupe Francophone des Myelodysplasies (GFM)
-
This is firsttherapy paper that demonstrates success using azacitidine in treating patients with MPNs that had transformed to AML
-
Thepot S, Itzykson R, Seegers V, et al. Treatment of progression of Philadelphia-negative myeloproliferative neoplasms to myelodysplastic syndrome or acute myeloid leukemia by azacitidine: a report on 54 cases on the behalf of the Groupe Francophone des Myelodysplasies (GFM). Blood 2010;116:3735-3742. This is firsttherapy paper that demonstrates success using azacitidine in treating patients with MPNs that had transformed to AML.
-
(2010)
Blood
, vol.116
, pp. 3735-3742
-
-
Thepot, S.1
Itzykson, R.2
Seegers, V.3
-
47
-
-
33745016073
-
Hemopoietic cell transplantation as curative therapy of myelodysplastic syndromes and myeloproliferative disorders
-
DOI 10.1016/j.beha.2005.07.009, PII S1521692605000964
-
Scott B, Deeg HJ. Hemopoietic cell transplantation as curative therapy of myelodysplastic syndromes and myeloproliferative disorders. Best Pract Res Clin Haematol. 2006;19:519-33. (Pubitemid 43869475)
-
(2006)
Best Practice and Research: Clinical Haematology
, vol.19
, Issue.3
, pp. 519-533
-
-
Scott, B.1
Deeg, H.J.2
-
48
-
-
33847077565
-
Marrow fibrosis as a risk factor for posttransplantation outcome in patients with advanced myelodysplastic syndrome or acute myeloid leukemia with multilineage dysplasia
-
Scott BL, Storer BE, Greene JE, et al.Marrow fibrosis as a risk factor for posttransplantation outcome in patients with advanced myelodysplastic syndrome or acute myeloid leukemia with multilineage dysplasia. Biol Blood Marrow Transplant. 2007;13:345-54.
-
(2007)
Biol Blood Marrow Transplant
, vol.13
, pp. 345-354
-
-
Scott, B.L.1
Storer, B.E.2
Greene, J.E.3
-
49
-
-
77953390081
-
Optimizing reduced-intensity conditioning regimens for myeloproliferative neoplasms
-
Ramakrishnan A, Sandmaier BM. Optimizing reduced-intensity conditioning regimens for myeloproliferative neoplasms. Expert Rev Hematol. 2010;3:23-33.
-
(2010)
Expert Rev Hematol
, vol.3
, pp. 23-33
-
-
Ramakrishnan, A.1
Sandmaier, B.M.2
-
50
-
-
71949121402
-
Pomalidomide is active in the treatment of anemia associated with myelofibrosis
-
Tefferi A, Verstovsek S, Barosi G, et al. Pomalidomide is active in the treatment of anemia associated with myelofibrosis. J Clin Oncol. 2009;27:4563-9.
-
(2009)
J Clin Oncol
, vol.27
, pp. 4563-4569
-
-
Tefferi, A.1
Verstovsek, S.2
Barosi, G.3
-
51
-
-
0034554739
-
Serious myeloproliferative reactions associated with the use of thalidomide in myelofibrosis with myeloid metaplasia
-
Tefferi A, Elliot MA. Serious myeloproliferative reactions associated with the use of thalidomide in myelofibrosis with myeloid metaplasia. Blood. 2000;96:4007.
-
(2000)
Blood
, vol.96
, pp. 4007
-
-
Tefferi, A.1
Elliot, M.A.2
-
52
-
-
33747167338
-
Lenalidomide therapy in myelofibrosis with myeloid metaplasia
-
DOI 10.1182/blood-2006-02-004572
-
Tefferi A, Cortes J, Verstovsek S, et al. Lenalidomide therapy inmyelofibrosis with myeloid metaplasia. Blood. 2006;108:1158-64. (Pubitemid 44232010)
-
(2006)
Blood
, vol.108
, Issue.4
, pp. 1158-1164
-
-
Tefferi, A.1
Cortes, J.2
Verstovsek, S.3
Mesa, R.A.4
Thomas, D.5
Lasho, T.L.6
Hogan, W.J.7
Litzow, M.R.8
Allred, J.B.9
Jones, D.10
Byrne, C.11
Zeldis, J.B.12
Ketterling, R.P.13
McClure, R.F.14
Giles, F.15
Kantarjian, H.M.16
-
53
-
-
79952164235
-
Unraveling the molecular pathophysiology of myelodysplastic syndromes
-
Bejar R, Levine R, Ebert BL. Unraveling the molecular pathophysiology of myelodysplastic syndromes. J Clin Oncol. 2011;29:504-15.
-
(2011)
J Clin Oncol
, vol.29
, pp. 504-515
-
-
Bejar, R.1
Levine, R.2
Ebert, B.L.3
-
54
-
-
84870805263
-
Phase II study of the JAK2 inhibitor, INCB018424, in patients with refractory leukemias including post-myeloproliferative disorder (MPD) acute myeloid leukemia (SAML) (Abstract 509)
-
Eghtedar A, Verstovsek S, Cortes JE, et al. Phase II study of the JAK2 inhibitor, INCB018424, in patients with refractory leukemias including post-myeloproliferative disorder (MPD) acute myeloid leukemia (SAML) (Abstract 509). Blood 2010.
-
(2010)
Blood
-
-
Eghtedar, A.1
Verstovsek, S.2
Cortes, J.E.3
-
55
-
-
79954611501
-
Phase i trial of hedgehog pathway inhibitor VISMODEGIB (GDC-0449) in patients with refractory, locally advanced or metastatic solid tumors
-
LoRusso PM, Rudin CM, Reddy JC, et al. Phase I trial of hedgehog pathway inhibitor VISMODEGIB (GDC-0449) in patients with refractory, locally advanced or metastatic solid tumors. Clin Cancer Res. 2011;17:2502-11.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 2502-2511
-
-
Lorusso, P.M.1
Rudin, C.M.2
Reddy, J.C.3
-
56
-
-
70349238733
-
Inhibition of thehedgehog pathway in advanced basal-cell carcinoma
-
Von Hoff DD, LoRusso PM, Rudin CM, et al. Inhibition of thehedgehog pathway in advanced basal-cell carcinoma. N Engl J Med. 2009;361:1164-72.
-
(2009)
N Engl J Med
, vol.361
, pp. 1164-1172
-
-
Von Hoff, D.D.1
Lorusso, P.M.2
Rudin, C.M.3
-
57
-
-
55949118445
-
Phase i and pharmacokinetic study of YM155, a small-molecule inhibitor of survivin
-
Tolcher AW, Mita A, Lewis LD, et al. Phase I and pharmacokinetic study of YM155, a small-molecule inhibitor of survivin. J Clin Oncol. 2008;26:5198-203.
-
(2008)
J Clin Oncol
, vol.26
, pp. 5198-5203
-
-
Tolcher, A.W.1
Mita, A.2
Lewis, L.D.3
-
58
-
-
77953279799
-
Phase i study of the novel survivin and CDC2/CDK1 inhibitor terameprocol in patients with advanced leukemias
-
ASH Annual Meeting Abstract #1039
-
Tibes R, McDonagh KT, Lekakis L, et al. Phase I study of the novel survivin and CDC2/CDK1 inhibitor terameprocol in patients with advanced leukemias. Blood 2009; ASH Annual Meeting Abstract #1039.
-
(2009)
Blood
-
-
Tibes, R.1
McDonagh, K.T.2
Lekakis, L.3
-
59
-
-
79958714273
-
A phase 1/2 study ofRAD001, an mTOR inhibitor, in patients with myelofibrosis: Final results
-
Vannucchi AM, Guglielmelli P, Lupo L, et al. A phase 1/2 study ofRAD001, an mTOR inhibitor, in patients with myelofibrosis: Final results. ASH Annual Meeting Abstracts. 2010;116:314.
-
(2010)
ASH Annual Meeting Abstracts
, vol.116
, pp. 314
-
-
Vannucchi, A.M.1
Guglielmelli, P.2
Lupo, L.3
-
60
-
-
77950917500
-
A phase i study ofLBH589, a novel histone deacetylase inhibitor in patients with primary myelofibrosis (PMF) and post-polycythemia/essential thrombocythemia myelofibrosis (post-PV/ET MF)
-
Mascarenhas J, Wang X, Rodriguez A, et al. A phase I study ofLBH589, a novel histone deacetylase inhibitor in patients with primary myelofibrosis (PMF) and post-polycythemia/essential thrombocythemia myelofibrosis (post-PV/ET MF). ASH Annual Meeting Abstracts. 2009;114:308.
-
(2009)
ASH Annual Meeting Abstracts
, vol.114
, pp. 308
-
-
Mascarenhas, J.1
Wang, X.2
Rodriguez, A.3
-
61
-
-
67549145773
-
A phase 2a study of the histone-deacetylase inhibitor ITF2357 in patients with JAK2V617F positive chronic myeloproliferative neoplasms
-
Rambaldi A, Dellacasa CM, Salmoiraghi S, et al. A phase 2a study of the histone-deacetylase inhibitor ITF2357 in patients with JAK2V617F positive chronic myeloproliferative neoplasms. Blood. 2008;112:100.
-
(2008)
Blood
, vol.112
, pp. 100
-
-
Rambaldi, A.1
Dellacasa, C.M.2
Salmoiraghi, S.3
-
62
-
-
70450257617
-
The interferon consensussequence binding protein (ICSBP/IRF8) activates transcription of the FANCF gene during myeloid differentiation
-
Saberwal G, Horvath E, Hu L, et al. The interferon consensussequence binding protein (ICSBP/IRF8) activates transcription of the FANCF gene during myeloid differentiation. J Biol Chem. 2009;284:33242-54.
-
(2009)
J Biol Chem
, vol.284
, pp. 33242-33254
-
-
Saberwal, G.1
Horvath, E.2
Hu, L.3
-
63
-
-
54049141336
-
Pegylated interferon alfa-2a induces complete hematologic and molecular responses withlow toxicity in polycythemia vera
-
Kiladjian JJ, Cassinat B, Chevret S, et al. Pegylated interferon alfa-2a induces complete hematologic and molecular responses withlow toxicity in polycythemia vera. Blood. 2008;112:3065-72.
-
(2008)
Blood
, vol.112
, pp. 3065-3072
-
-
Kiladjian, J.J.1
Cassinat, B.2
Chevret, S.3
-
64
-
-
73949090770
-
Pegylated interferon alfa-2a yields high rates of hematologic and molecular response in patients with advanced essential thrombocythemia and polycythemia vera
-
Quintas-Cardama A, Kantarjian H, Manshouri T, et al. Pegylated interferon alfa-2a yields high rates of hematologic and molecular response in patients with advanced essential thrombocythemia and polycythemia vera. J Clin Oncol. 2009;27:5418-24.
-
(2009)
J Clin Oncol
, vol.27
, pp. 5418-24
-
-
Quintas-Cardama, A.1
Kantarjian, H.2
Manshouri, T.3
-
65
-
-
40549094646
-
Constitutive activation of SHP2 in mice cooperates with ICSBP deficiency to accelerate progression to acute myeloid leukemia
-
DOI 10.1172/JCI33742
-
Konieczna I, Horvath E, Wang H, et al. Constitutive activation of Shp2 in mice cooperates with ICSBP deficiency to accelerate progression to acute myeloid leukemia. J Clin Invest. 2008;118:853-67. (Pubitemid 351364594)
-
(2008)
Journal of Clinical Investigation
, vol.118
, Issue.3
, pp. 853-867
-
-
Konieczna, I.1
Horvath, E.2
Wang, H.3
Lindsey, S.4
Saberwal, G.5
Bei, L.6
Huang, W.7
Platanias, L.8
Eklund, E.A.9
-
66
-
-
33646512610
-
Survivin expression, apoptosis and proliferation in chronic myelomonocytic leukemia
-
Invernizzi R, Travaglino E, Benatti C, et al. Survivin expression, apoptosis and proliferation in chronic myelomonocytic leukemia. Eur J Haematol. 2006;76:494-501.
-
(2006)
Eur J Haematol
, vol.76
, pp. 494-501
-
-
Invernizzi, R.1
Travaglino, E.2
Benatti, C.3
-
67
-
-
77954658823
-
IDH1 and IDH2 mutation studies in 1473 patients with chronic-, fibrotic-or blast-phase essential thrombocythemia, polycythemia vera or myelofibrosis
-
Tefferi A, Lasho TL, Abdel-Wahab O, et al. IDH1 and IDH2 mutation studies in 1473 patients with chronic-, fibrotic-or blast-phase essential thrombocythemia, polycythemia vera or myelofibrosis. Leukemia. 2010;24:1302-9.
-
(2010)
Leukemia
, vol.24
, pp. 1302-1309
-
-
Tefferi, A.1
Lasho, T.L.2
Abdel-Wahab, O.3
-
68
-
-
75449119103
-
Somatic mutations of IDH1 and IDH2 in the leukemic transformation of myeloproliferative neoplasms
-
Green A, Beer P. Somatic mutations of IDH1 and IDH2 in the leukemic transformation of myeloproliferative neoplasms. N EnglJ Med. 2010;362:369-70.
-
(2010)
N EnglJ Med
, vol.362
, pp. 369-370
-
-
Green, A.1
Beer, P.2
-
69
-
-
73949129831
-
AML1/RUNX1 point mutationpossibly promotes leukemic transformation in myeloproliferative neoplasms
-
Ding Y, Harada Y, Imagawa J, et al. AML1/RUNX1 point mutationpossibly promotes leukemic transformation in myeloproliferative neoplasms. Blood. 2009;114:5201-5.
-
(2009)
Blood
, vol.114
, pp. 5201-5205
-
-
Ding, Y.1
Harada, Y.2
Imagawa, J.3
-
70
-
-
77956696835
-
Safety and efficacy of INCB018424, a JAK1 and JAK2 inhibitor, in myelofibrosis
-
Verstovsek S, Kantarjian H, et al. Safety and efficacy of INCB018424, a JAK1 and JAK2 inhibitor, in myelofibrosis. N Engl J Med. 2010;363(12):1117-27.
-
(2010)
N Engl J Med
, vol.363
, Issue.12
, pp. 1117-1127
-
-
Verstovsek, S.1
Kantarjian, H.2
-
71
-
-
79959605267
-
Durable responses with the JAK1/ JAK2 Inhibitor, INCB018424. in patients with polycythemia vera(PV) and essential thrombocythemia (ET) Refractory or intolerant to hydroxyurea (HU)
-
ASH Annual Meeting Abstracts
-
Verstovsek S, Passamonti F, et al. Durable Responses with the JAK1/ JAK2 Inhibitor, INCB018424, In Patients with Polycythemia Vera(PV) and Essential Thrombocythemia (ET) Refractory or Intolerant to Hydroxyurea (HU). Blood. 2010;116(21):313. ASH Annual Meeting Abstracts.
-
(2010)
Blood
, vol.116
, Issue.21
, pp. 313
-
-
Verstovsek, S.1
Passamonti, F.2
-
72
-
-
79952333359
-
Safety and efficacy of TG101348, a selective JAK2 inhibitor, in myelofibrosis
-
Pardanani A, Gotlib JR, Jamieson C, et al. Safety and efficacy of TG101348, a selective JAK2 inhibitor, in myelofibrosis. J Clin Oncol. 2011;29(7):789-96.
-
(2011)
J Clin Oncol
, vol.29
, Issue.7
, pp. 789-796
-
-
Pardanani, A.1
Gotlib, J.R.2
Jamieson, C.3
-
73
-
-
79958715032
-
Phase 1/2 Study of SB1518, a Novel JAK2/FLT3 Inhibitor. in the Treatment of Primary Myelofibrosis
-
ASH Annual Meeting Abstracts
-
Verstovsek S, Deeg HJ, et al. Phase 1/2 Study of SB1518, a Novel JAK2/FLT3 Inhibitor, In the Treatment of Primary Myelofibrosis. Blood. 2010;116(21):3082. ASH Annual Meeting Abstracts.
-
(2010)
Blood
, vol.116
, Issue.21
, pp. 3082
-
-
Verstovsek, S.1
Deeg, H.J.2
-
74
-
-
69249192267
-
An open-label study of cep-701in patients with jak2 v617f-positive polycythemia vera and essential thrombocytosis
-
ASH Annual Meeting Abstracts
-
Moliterno AR, Roboz GJ, et al. An Open-Label Study of CEP-701in Patients with JAK2 V617F-Positive Polycythemia Vera and Essential Thrombocytosis. Blood. 2008;112(11):99. ASH Annual Meeting Abstracts.
-
(2008)
Blood
, vol.112
, Issue.11
, pp. 99
-
-
Moliterno, A.R.1
Roboz, G.J.2
|