Research spotlight: Bioreducible polymer-delivered siRNA targeting human telomerase reverse transcriptase for human cancer gene therapy

Therapeutic Delivery

Volumn 3, Issue 4, 2012, Pages 439-442

  Xia, Wei ^a,b   Lin, Chao ^a,c  

^a TONGJI UNIVERSITY SCHOOL OF MEDICINE   (China)

^b People s Hospital of Shanghai Putuo District   (China)

^c TONGJI UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BIOREDUCIBLE DISULFIDE BASED POLYETHYLENIMINE; DRUG CARRIER; FLUORESCENT DYE; LIPOFECTAMINE; SMALL INTERFERING RNA; TELOMERASE REVERSE TRANSCRIPTASE; UNCLASSIFIED DRUG; DISULFIDE; DRUG DERIVATIVE; POLYETHYLENEIMINE; POLYMER; TELOMERASE; TERT PROTEIN, HUMAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BIOCOMPATIBILITY; CANCER GENE THERAPY; CANCER INHIBITION; CHRONIC TOXICITY; CONTROLLED STUDY; CYTOTOXICITY; DISULFIDE BOND; DRUG ACCUMULATION; DRUG DISTRIBUTION; GENE DELIVERY SYSTEM; GENE SILENCING; HEART; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; KIDNEY; KIDNEY FUNCTION; LIVER; LIVER FUNCTION; LUNG; MOUSE; NONHUMAN; PRIORITY JOURNAL; SPLEEN; TOXICITY TESTING; ANIMAL; CELL PROLIFERATION; CHEMISTRY; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENE THERAPY; GENETICS; METABOLISM; METHODOLOGY; NEOPLASM; PATHOLOGY; RNA INTERFERENCE; RNA STABILITY; TUMOR VOLUME;

ANIMALS; CELL PROLIFERATION; DISULFIDES; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, NEOPLASTIC; GENETIC THERAPY; HUMANS; NEOPLASMS; POLYETHYLENEIMINE; POLYMERS; RNA INTERFERENCE; RNA STABILITY; RNA, SMALL INTERFERING; TELOMERASE; TUMOR BURDEN;

EID: 84859231071     PISSN: 20415990     EISSN: 20416008     Source Type: Journal    
DOI: 10.4155/tde.12.24     Document Type: Article

References (12)

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