Pharmacokinetic interaction between tacrolimus and amlodipine in a renal transplant child

Transplantation

Volumn 93, Issue 7, 2012, Pages

  Zhao, Wei ^a,b   Baudouin, Véronique ^a   Fakhoury, May ^a   Storme, Thomas ^a   Deschênes, Georges ^a   Jacqz Aigrain, Evelyne ^a,b  

^a HÔPITAL ROBERT DEBRÉ   (France)

^b INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AMLODIPINE; ENALAPRIL; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PREDNISONE; TACROLIMUS;

ABCB1 GENE; AREA UNDER THE CURVE; CASE REPORT; CHILD; CREATININE BLOOD LEVEL; CYP3A4 GENE; CYP3A5 GENE; DRUG ANTAGONISM; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DOSE REDUCTION; DRUG MONITORING; ENZYME MULTIPLIED IMMUNOASSAY TECHNIQUE; HETEROZYGOSITY; HOMOZYGOSITY; HUMAN; HYPERTENSION; IMMUNOSUPPRESSIVE TREATMENT; KIDNEY FAILURE; KIDNEY HYPOPLASIA; KIDNEY TRANSPLANTATION; LETTER; MALE; PHARMACOGENOMICS; PRESCHOOL CHILD; PRIORITY JOURNAL; VESICOURETERAL REFLUX;

AMLODIPINE; ANTIHYPERTENSIVE AGENTS; CHILD, PRESCHOOL; CYTOCHROME P-450 CYP3A; DRUG INTERACTIONS; GRAFT REJECTION; HUMANS; HYPERTENSION; IMMUNOSUPPRESSIVE AGENTS; KIDNEY TRANSPLANTATION; MALE; P-GLYCOPROTEIN; PHARMACOGENETICS; TACROLIMUS; TREATMENT OUTCOME;

EID: 84859228868     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/TP.0b013e318249b180     Document Type: Letter

References (9)

1. Silverstein DM, Palmer J, Baluarte HJ, et al. Use of calcium-channel blockers in pediatric renal transplant recipients. Pediatr Transplant 1999; 3: 288
2. Kim KA, Park PW, Lee OJ, et al. Effect of CYP3A5*3 genotype on the pharmacokinetics and pharmacodynamics of amlodipine in healthy Korean subjects. Clin Pharmacol Ther 2006; 80: 646
3. Bhatnagar V, Garcia EP, O'Connor DT, et al. CYP3A4 and CYP3A5 polymorphisms and blood pressure response to amlodipine among African-American men and women with early hypertensive renal disease. Am J Nephrol 2010; 31: 95
4. Zhao W, Elie V, Roussey G, et al. Population pharmacokinetics and pharmacogenetics of tacrolimus in de novo pediatric kidney transplant recipients. Clin Pharmacol Ther 2009; 86: 609
5. Seifedin RA, Marcos-Alvarez A, Gordon FD, et al. Nifedipine interaction with tacrolimus in liver transplant recipients. Ann Pharmacother 1997; 31: 571
6. Katoh M, Nakajima M, Shimada N, et al. Inhibition of human cytochrome P450 enzymes by 1,4-dihydropyridine calcium antagonists: Prediction of in vivo drug-drug interactions. Eur J Clin Pharmacol 2000; 55: 843
7. Katoh M, Nakajima M, Yamazaki H, et al. Inhibitory potencies of 1,4-dihydropyridine calcium antagonists to P-glycoproteinmediated transport: Comparison with the effects on CYP3A4. Pharm Res 2000; 17: 1189
8. Pesavento TE, Jones PA, Julian BA, et al. Amlodipine increases cyclosporine levels in hypertensive renal transplant patients: Results of a prospective study. J Am Soc Nephrol 1996; 7: 831
9. Nishio S, Watanabe H, Kosuge K, et al. Interaction between amlodipine and simvastatin in patients with hypercholesterolemia and hypertension. Hypertens Res 2005; 28: 223.