Anti-CD44 mAb remodels biological behaviors of spheroid cells with stemness from human ovarian cancer cell line SKOV-3

Chinese Science Bulletin

Volumn 57, Issue 11, 2012, Pages 1288-1297

  Gu, Chao ^a   Du, Yong Rui ^b   Gao, Yan ^b   Yao, Zhi ^a   Gu, Xin ^a   Zhang, Qiu Yue ^a   Xu, Jing Jing ^a   Deng, Wei Min ^a  

^a TIANJIN MEDICAL UNIVERSITY   (China)

^b Tianjin Central Gynecology and Obstetrics Hospital   (China)

Author keywords

antibody; cancer stem cell (CSC); CD44; ovarian cancer (OVCA); targeting therapy

Indexed keywords

CYCLINA;

EID: 84859219609     PISSN: 10016538     EISSN: 18619541     Source Type: Journal    
DOI: 10.1007/s11434-012-5075-5     Document Type: Article

References (38)

1. Mimeault M, Batra S K. Functions of tumorigenic and migrating cancer progenitor cells in cancer progression and metastasis and their therapeutic implications. Cancer Metast Rev, 2007, 26: 203-214.
2. Dean M, Fojo T, Bates S. Tumor stem cells and drug resistance. Nat Rev Cancer, 2005, 5: 275-284.
3. Mimeault M, Hauke R, Mehta P P, et al. Recent advances in cancer stem/progenitor cell research: Therapeutic implications for overcoming resistance to the most aggressive cancers. J Cell Mol Med, 2007, 11: 981-1011.
4. Brabletz T, Jung A, Spaderna S, et al. Opinion: Migrating cancer stem cells-An integrated concept of malignant tumor progression. Nat Rev Cancer, 2005, 5: 744-749.
5. Miller S J, Lavker R M, Sun T T. Interpreting epithelial cancer biology in the context of stem cells: Tumor properties and therapeutic implications. Biochim Biophys Acta, 2005, 1756: 25-52.
6. Massard C, Deutsch E, Soria J C. Tumor stem cell-targeted treatment: Elimination or differentiation. Ann Oncol, 2006, 17: 1620-1624.
7. Ponnusamy M P, Batra S K. Ovarian cancer: Emerging concept on cancer stem cells. J Ovarian Res, 2008, 1: 4-12.
8. Misaghian N, Ligresti G, Steelman L S, et al. Targeting the leukemic stem cell: The Holy Grail of leukemia therapy. Leukemia, 2008, 23: 25-42.
9. Charrad R S, Gadhoum Z, Qi J Y, et al. Effects of anti-CD44 monoclonal antibodies on differentiation and apoptosis of human myeloid leukemia cell lines. Blood, 2002, 99: 290-299.
10. Gadhoum Z, Delaunay J, Maquarre E, et al. The effect of anti-CD44 monoclonal antibodies on differentiation and proliferation of human acute myeloid leukemia cells. Leuk Lymphoma, 2004, 45: 1501-1510.
11. Gadhoum Z, Leibovitch M P, Qi J Y, et al. CD44: A new means to inhibit acute myeloid leukemia cell proliferation via p27 Kip1. Blood, 2004, 103: 1059-1068.
12. Jin L Q, Hope K J, Zhai Q L, et al. Targeting of CD44 eradicates human acute myeloid leukemic stem cells. Nat Med, 2006, 12: 1167-1174.
13. Zhang S, Balch C, Chan M W, et al. Identification and characterization of ovarian cancer-initiating cells from primary human tumors. Cancer Res, 2008, 68: 4311-4320.
14. Bapat S A, Mali A M, Koppikar C B, et al. Stem and progenitor-like cells contribute to the aggressive behavior of human epithelial ovari an cancer. Cancer Res, 2005, 65: 3025-3029.
15. Patel D D, Hale L P, Whichard L P, et al. Expression of CD44 molecules and CD44 ligands during human thymic fetal development: Expression of CD44 isoforms is developmentally regulated. Int Immunol, 1995, 7: 277-286.
16. Li Z, Shen X T, Cao L, et al. Bone morphogenetic protein 2 improves patellar tendon healing by promoting migration and proliferation of tenocytes. Chin Sci Bull, 2011, 56: 1361-1369.
17. Li H Z, Wang Y, Gao Y, et al. Effects of raf kinase inhibitor protein expression on metastasis and progression of human epithelial ovarian cancer. Mol Cancer Res, 2008, 6: 917-928.
18. Matsui W, Wang Q, Barber J P, et al. Clonogenic multiple myeloma progenitors, stem cell properties, and drug resistance. Cancer Res, 2008, 68: 190-197.
19. Takubo K, Ohmura M, Azuma M, et al. Stem cell defects in ATM-deficient undifferentiated spermatogonia through DNA damage-induced cell-cycle arrest. Cell Stem Cell, 2008, 2: 170-182.
20. Pascal L E, Oudes A J, Petersen T W, et al. Molecular and cellular characterization of ABCG2 in the prostate. BMC Urol, 2007, 7: 6-18.
21. Croker A K, Goodale D, Chu J, et al. High aldehyde dehydrogenase and expression of cancer stem cell markers selects for breast cancer cells with enhanced malignant and metastatic ability. J Cell Mol Med, 2009, 13: 2236-2252.
22. Wang J, Guo L P, Chen L Z. Identification of cancer stem cell-like side population cells in human nasopharyngeal carcinoma cell line. Cancer Res, 2007, 67: 3716-3724.
23. Kondo T, Setoguchi T, Taga T. Persistence of a small subpopulation of cancer stem-like cells in the C6 glioma cell line. Proc Natl Acad Sci USA, 2004, 101: 781-786.
24. Maria M H, Alvin V N, Stephen L, et al. Side population in human lung cancer cell lines and tumors is enriched with stem-like cancer cells. Cancer Res, 2007, 67: 4827-4833.
25. Li Y F, Xiao B, Lai Z S, et al. Spheres isolated from Colo205 cell line possess cancer stem-like cells under serum-free culture condition. J South Med Univ, 2008, 28: 236-240.
26. Dou J, Pan M, Wen P, et al. Isolation and identification of cancer stem-like cells from murine melanoma cell lines. Cell Mol Immunol, 2007, 4: 467-472.
27. Wu C, Wei Q, Utomo V, et al. Side population cells isolated from mesenchymal neoplasms have tumor initiating potential. Cancer Res, 2007, 67: 8216-8222.
28. Al-Hajj M, Wicha M S, Benito-Hernandez A. Prospective identification of tumorigenic breast cancer cells. Proc Natl Acad Sci USA, 2003, 100: 3983-3988.
29. Singh S K, Hawkins C, Clarke I D, et al. Identification of human brain tumour initiating cells. Nature, 2004, 432: 396-401.
30. Hemmati H D, Nakano I, Lazareff J A, et al. Cancerous stem cells can arise from pediatric brain tumors. Proc Natl Acad Sci USA, 2003, 100: 15178-15183.
31. Singh S K, Clarke I D, Terasaki M, et al. Identification of a cancer stem cell in human brain tumors. Cancer Res, 2003, 63: 5821-5828.
32. Tan B T, Park C Y, Ailles L E, et al. The cancer stem cell hypothesis: A work in progress. Lab Invest, 2006, 86: 1203-1207.
33. Gao G, Dou Q P. G(1) phase-dependent expression of bcl-2 mRNA and protein correlates with chemoresistance of human cancer cells. Mol Pharmacol, 2000, 58: 1001-1010.
34. Makrydimas G, Zagorianakou N, Zagorianakou P, et al. CD44 family and gynaecological cancer. In Vivo, 2003, 17: 633-640.
35. Cho E Y, Choi Y, Chae S W, et al. Immunohistochemical study of the expression of adhesion molecules in ovarian serous neoplasms. Pathol Int, 2006, 56: 62-70.
36. Knowlton K, Mancini M, Creason S, et al. Bcl-2 slows in vitro breast cancer growth despite its antiapoptotic effect. J Surg Res, 1998, 76: 22-26.
37. Cannistra S A, Kansas G S, Niloff J, et al. Binding of ovarian cancer cells to peritoneal mesothelium in vitro is partly mediated by CD44H. Cancer Res, 1993, 53: 3830-3838.
38. Zada A A, Singh S M, Reddy V A, et al. Downregulation of c-Jun expression and cell cycle regulatory molecules in acute myeloid leukemia cells upon CD44 ligation. Oncogene, 2003, 22: 2296-2308.