Associations of serum aflatoxin B 1-lysine adduct level with socio-demographic factors and aflatoxins intake from nuts and related nut products in Malaysia

International Journal of Hygiene and Environmental Health

Volumn 215, Issue 3, 2012, Pages 368-372

  Leong, Yin Hui ^a   Rosma, Ahmad ^b   Latiff, Aishah A ^a   Izzah, A Nurul ^c  

^a SCHOOL OF PHYSICS   (Malaysia)

^b Universiti Sains Malaysia   (Malaysia)

^c INSTITUTE FOR MEDICAL RESEARCH   (Malaysia)

Author keywords

Aflatoxin B 1; Aflatoxin B 1 lysine adduct; Dietary exposure; Malaysia

Indexed keywords

AFLATOXIN B1; AFLATOXIN B1 LYSINE ADDUCT; AFLATOXIN B1-LYSINE ADDUCT; LYSINE;

ADULT; ARTICLE; BLOOD; CHEMISTRY; DIET; FEMALE; HUMAN; MALAYSIA; MALE; MICROBIOLOGY; MIDDLE AGED; NUT; SOCIOECONOMICS;

ADULT; AFLATOXIN B1; DIET; FEMALE; HUMANS; LYSINE; MALAYSIA; MALE; MIDDLE AGED; NUTS; SOCIOECONOMIC FACTORS;

EID: 84859218298     PISSN: 14384639     EISSN: 1618131X     Source Type: Journal    
DOI: 10.1016/j.ijheh.2011.12.005     Document Type: Article

References (42)

1. Bhat R., Rai R.V., Karim A.A. Mycotoxins in food and feed: present status and future concerns. Compr. Rev. Food Sci. F 2010, 9:57-81.
2. Chao T.C., Lo D.S.T., Bloodworth B.C., Gunasegaram R., Koh T.H., Ng H.S. Aflatoxin exposure in Singapore: blood aflatoxin levels in normal subjects, hepatitis B virus carriers and primary hepatocellular carcinoma patients. Med. Sci. Law 1994, 34(4):289-298.
3. Chapot B., Wild C.P. ELISA for quantification of aflatoxin-albumin adducts and their application to human exposure assessment. Techniques in Diagnostic Pathology 1991, 135-155. Academic Press, London. M. Warthol, D. van Velzer, G. Bullock (Eds.).
4. Egal S., Hounsa A., Gong Y.Y., Turner P.C., Wild C.P., Hall A.J., Hell K., Cardwell K.F. Dietary exposure to aflatoxin from maize and groundnut in young children from Benin and Togo, West Africa. Int. J. Food Microbiol. 2005, 104:215-224.
5. Fung F., Clark R.F. Health effects of mycotoxins: a toxicological overview. J. Toxicol. 2004, 42:217-234.
6. Gan L.S., Skipper P.L., Peng X.C., Groopman J.D., Chen J.S., Wogan G.N., Tannenbaum S.R. Serum albumin adducts in the molecular epidemiology of aflatoxin carcinogenesis: correlation with aflatoxin B1 intake and urinary excretion of aflatoxin M1. Carcinogenesis 1988, 9:1323-1325.
7. Gong Y.Y., Egal S., Hounsa A., Turner P.C., Hall A.J., Cardwell K.F., Wild C.P. Determinants of aflatoxin exposure in young children from Benin and Togo, West Africa: the critical role of weaning. Int. J. Epidemiol. 2003, 32:556-562.
8. Guengerich F.P., Arneson K.O., Williams K.M., Deng Z., Harris T.M. Reaction of aflatoxin B1 oxidation products with lysine. Chem. Res. Toxicol. 2002, 15:780-792.
9. Guengerich F.P., Johnson W.W., Shimada T., Ueng Y.F., Yamazaki H., Langouet S. Activation and detoxication of aflatoxin B1. Mutat. Res. 1998, 402:121-128.
10. IARC Some naturally occurring substances: Food items and constituents, heterocyclic aromatic amines and mycotoxins. IARC Monograph on the Evaluation of Carcinogenic Risk to Humans 1993, http://monographs.iarc.fr/ENG/Monographs/vol56/volume56.pdf (accessed 22.04.10).
11. JECFA, 2008. Sixty-eighth report of the joint FAO/WHO expert committee on food additives. Evaluation of Certain Food Additives and Contaminants. WHO Technical Report Series 947. (accessed 12.03.10). http://whqlibdoc.who.int/publications/2007/9789241209472_eng.pdf.
12. Jolly P., Jiang Y., Ellis W., Awuah R., Nnedu O., Phillips T., Wang J.-S., Afriyie-Gyawu E., Tang L., Person S., Williams J., Jolly C. Determinants of aflatoxin levels in Ghanaians: sociodemographic factors, knowledge of aflatoxin and food handling and consumption practices. Int. J. Hyg. Environ. Health 2006, 209(4):345-358.
13. Jolly P.E., Jiang Y., Ellis W.O., Awuah R.T., Appawu J., Nnedu O., Stiles J.K., Wang J.-S., Adjei O., Jolly C.M., Williams J.H. Association between aflatoxin exposure and health characteristics, liver function, hepatitis and malaria infections in Ghanaians. J. Nutr. Environ. Med. 2007, 16(3-4):242-257.
14. Leong Y.-H., Ismail N., Latif A.A., Ahmad R. Aflatoxin occurrence in nuts and commercial nutty products in Malaysia. Food Cont. 2010, 21:334-338.
15. Leong Y.-H., Ismail N., Latif A.A., Nurul Izzah A., Narazah M.Y., Nurul Ain A.B. Nuts consumption pattern among Malaysian adults: a socio-demographic and dietary behaviour perspective. Int. Food Res. J. 2011, 18(1):319-328.
16. Leong Y.-H., Rosmah A., Latiff A.A., Ahmad N.I. Exposure assessment and risk characterization of aflatoxin B1 in Malaysia. Mycotox Res. 2011, 27:207-214.
17. Lundsgaard-Hansen P. Physiology and pathophysiology of colloid osmotic pressure and albumin metabolism. Curr. Stud. Hematol. Bl. 1986, 53:1-17.
18. Mat Isa A., Tee E.S. The status of aflatoxin research in Malaysia. Country report presented at the first Technical Consultation of ASEAN Mycotoxin Experts. 3-8 December 1984 Kuala Lumpur 1984.
19. McCoy L., Scholl P.F., Schleicher R., Groopman J.D., Powers C., Pfeiffer C.M. Analysis of aflatoxin B1-lysine adducts in human serum by isotope dilution liquid chromatography tandem mass spectrometry. Rapid Commun. Mass Spectrom. 2005, 19:2203-2210.
20. Ministry Health of Malaysia, 2006. (accessed 22 April 2010). http://www.makna.org.my/PDF/MalaysiaCancerStatistics.pdf.
21. O'Riordan M.J., Wilkinson M.G. A survey of the incidence and level of aflatoxin determination in a range of imported spices preparations on the Irish retail market. Food Chem. 2008, 107:1429-1435.
22. Qian G.S., Ross R.K., Yu M.C., Yuan J.M., Gao Y.T., Henderson B.E., Wogan G.N., Groopman J.D. A follow-up study of urinary markers of aflatoxin exposure and liver cancer risk in Shanghai, People's Republic of China. Cancer Epidemiol. Biomarkers Prev. 1994, 3:3-10.
23. Revankar S.G. Clinical implications of mycotoxins and stachybotrys. Am. J. Med. Sci. 2003, 325:262-274.
24. Sabbioni G., Ambs S., Wogan G.N., Groopman J.D. The aflatoxin-lysine adduct quantified by high performance liquid chromatography from human serum albumin samples. Carcinogenesis 1990, 11:2063-2066.
25. 1-serum albumin adduct and its relevance to the measurement of human exposure to aflatoxins. Carcinogenesis 1991, 12(1):97-103.
26. Scholl P.F., Turner P.C., Sutcliffe A.E., Sylla A., Diallo M.S., Friesen M.D., Groopman J.D., Wild C.P. Quantitative comparison of aflatoxin B1 serum albumin adducts in humans by isotope dilution mass spectrometry and enzyme linked immunosorbent assay. Cancer Epidemiol. Biomarkers Prev. 2006, 15:823-826.
27. Seeff L.B., Hoofnagle J.H. Epidemiology of hepatocellular carcinoma in areas of low hepatitis B and hepatitis C endemicity. Oncogene 2006, 25:3771-3777.
28. 1 biomarker blood levels in pregnant women in Kumasi, Ghana. Trop. Med. Int. Health 2010, 15(2):160-167. (8).
29. 1-albumin adducts in the United Kingdom population: implications for aflatoxin B1 exposure in the United Kingdom. Cancer Epidemiol. Biomarkers Prev. 1998, 7:441-447.
30. Turner P.C., Loffredo C., El-Kafrawy S., Ezzat S., Abdel-Latif Eissa S., El-Daly M., Nada O., Abdel-Hamid M. Pilot survey of aflatoxin-albumin adducts in sera from Egypt. Food Addit. Contam. 2008, 25(5):583-587.
31. Walton M., Egner P., Scholl P.F., Walker J., Kensler T.J., Groopman J.D. Liquid chromatography electrospray-mass spectrometry of urinary aflatoxin biomarkers: characterization and application to dosimetry and chemoprevention in rats. Chem. Res. Toxicol. 2001, 14(7):919-926.
32. Wang J.S., Huang T., Su J., Liang F., Wei Z., Liang Y., Luo H., Kuang S.Y., Qian G.S., Sun G., He X., Kensler T.W., Groopman J.D. Hepatocellular carcinoma and aflatoxin exposure in Zhuqing Village, Fusui County, People's Republic of China. Cancer Epidemiol. Biomarkers Prev. 2001, 10:143-146.
33. Wang J.-S., Qian G.-S., Zarba A., He X., Zhu Y.-R., Zhang B.-C., Jacobson L., Gange S.J., Muñoz A., Kensler T.W., Groopman J.D. Temporal patterns of aflatoxin-albumin adducts in hepatitis B surface antigen-positive and antigen-negative residents of Daxin, Qidong County, People's Republic of China. Cancer Epidemiol. Biomarkers Prev. 1996, 5:253-261.
34. WHO Safety Evaluation of Certain Food Additives and Contaminants. Aflatoxins. WHO Food Additives Series 40 1998, World Health Organization, Geneva.
35. Wild C.P., Gong Y.Y. Mycotoxins and human disease: a largely ignored global health issue. Carcinogenesis 2010, 31(1):71-82.
36. Wild C.P., Hudson G.J., Sabbioni G., Chapot B., Hall A.J., Wogan G.N., Whittle H., Montesano R., Groopman J.D. Dietary intake of aflatoxins and the level of albumin-bound aflatoxin in peripheral blood in The Gambia, West Africa. Cancer Epidemiol. Biomarkers Prev. 1992, 1:229-234.
37. Wild C.P., Jansen L.M., Cova L., Montesano R. Molecular dosimetry of aflatoxin exposure: contribution to understanding the multifactorial aetiopathogenesis of primary hepatocellular carcinoma (PHC) with particular reference to hepatitis B virus. Environ. Health Perspect. 1993, 99:115-122.
38. Wild C.P., Jiang Y.-Z., Allen S.J., Jansen L.A.M., Hall A.J., Montesano R. Aflatoxin-albumin adducts in human sera from different regions of the world. Carcinogenesis 1990, 11(12):2271-2274.
39. Wild C.P., Jiang Y.-Z., Sabbioni G., Chapot B., Montesano R. Evaluation of methods for quantitation of aflatoxin albumin adducts and their application to human exposure assessment. Cancer Res. 1990, 50:245-251.
40. Wild C.P., Turner P.C. The toxicology of aflatoxins as a basis for public health decisions. Mutagenesis 2002, 17(6):471-481.
41. Williams J.H., Phillips T.D., Jolly P.E., Stiles J.K., Jolly C.M., Aggarwal D. Human aflatoxicosis in developing countries: a review of toxicology, exposure, potential health consequences, and interventions. Am. J. Clin. Nutr. 2004, 80:1106-1122.
42. Xu L., Qian G., Tang L., Su J., Wang J.-S. Genetic variations of hepatitis B virus and serum aflatoxin-lysine adduct on high risk of hepatocellular carcinoma in Southern Guangxi. China. J. Hepatol. 2010, 53:671-676.