Silent pulmonary embolism in patients with proximal deep vein thrombosis in the lower limbs

Journal of Thrombosis and Haemostasis

Volumn 10, Issue 4, 2012, Pages 564-571

  Tzoran, I ^a   Saharov, G ^a   Brenner, B ^a   Delsart, D ^b,c,d   Roman P ^e   Visona A ^f   Jimenez D ^g   Monreal, M ^h  

^a RAMBAM MEDICAL CENTER   (Israel)

^b INSERM   (France)

^c University Jean Monnet of Saint Etienne EA3065   (France)

^d HÔPITAL NORD   (France)

^e HOSPITAL GENERAL DE REQUENA   (Spain)

^f San Giacomo Hospital   (Italy)

^g HOSPITAL RAMÓN Y CAJAL   (Spain)

^h HOSPITAL UNIVERSITARI GERMANS TRIAS I PUJOL   (Spain)

Author keywords

Anticoagulation; Bleeding; Deep vein thrombosis; Pulmonary embolism

Indexed keywords

ANTICOAGULANT AGENT; ANTIVITAMIN K; HEPARIN; LOW MOLECULAR WEIGHT HEPARIN;

ANTICOAGULANT THERAPY; ARTICLE; BLEEDING; CLINICAL FEATURE; CONTROLLED STUDY; DEEP VEIN THROMBOSIS; DIAGNOSTIC TEST; DRUG SUBSTITUTION; DRUG WITHDRAWAL; FEMALE; HUMAN; INTERNATIONAL NORMALIZED RATIO; LUNG EMBOLISM; LUNG SCINTISCANNING; LUNG VENTILATION PERFUSION RATIO; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; SILENT LUNG EMBOLISM; SPIRAL COMPUTER ASSISTED TOMOGRAPHY; TREATMENT OUTCOME; VENA CAVA FILTER;

AGED; AGED, 80 AND OVER; ANTICOAGULANTS; ASYMPTOMATIC DISEASES; CHI-SQUARE DISTRIBUTION; EUROPE; FEMALE; HEMORRHAGE; HUMANS; INCIDENCE; ISRAEL; LOGISTIC MODELS; LOWER EXTREMITY; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; ODDS RATIO; PROSPECTIVE STUDIES; PULMONARY EMBOLISM; REGISTRIES; RISK ASSESSMENT; RISK FACTORS; SURVIVAL ANALYSIS; TIME FACTORS; TREATMENT OUTCOME; VENOUS THROMBOSIS;

EID: 84859207567     PISSN: 15387933     EISSN: 15387836     Source Type: Journal    
DOI: 10.1111/j.1538-7836.2012.04648.x     Document Type: Article

References (20)

1. Kistner RL, Ball JJ, Nordyke RA, Freeman GC. Incidence of pulmonary embolism in the course of thrombophlebitis of the lower extremities. Am J Surg 1972; 124: 169-76.
2. Browse NL, Clemenson G, Croft DN. Fibrinogen-detectable thrombosis in the legs and pulmonary embolism. Br Med J 1974; 1: 603-4.
3. Huisman MV, Büller HR, Ten Cate JW, van Royen EA, Vreeken J, Kersten MJ, Bakx B. Unexpected high prevalence of silent pulmonary embolism in patients with deep venous thrombosis. Chest 1989; 95: 498-502.
4. Monreal M, Rey-Joly C, Ruíz J, Salvador R, Lafoz E, Viver E. Asymptomatic pulmonary embolism in patients with deep vein thrombosis. Is it useful to take a lung scan to rule out this condition?. J Cardiovasc Surg 1989; 30: 104-7.
5. Cuppini S, Cattelan AM, Casara D, Prandoni P. Occult pulmonary embolism in patients with proximal deep venous thrombosis. Ann Ital Med Int 1991; 6: 1-5.
6. Moser KM, Fedullo PF, LitteJohn JK, Crawford R. Frequent asymptomatic pulmonary embolism in patients with deep venous trombosis. JAMA 1994; 271: 223-5.
7. Monreal M, Lafoz E, Ruiz J, Callejas JM, Arias A. Recurrent pulmonary embolism in patients treated because of acute venous thromboembolism: a prospective study. Eur J Vasc Surg 1994; 8: 584-9.
8. Pesavento R, Lusiani L, Visonà A, Bonanome A, Zanco P, Perissinotto C, Pagnan A. Prevalence of clinically silent pulmonary embolism in deep venous thrombosis of the legs. Minerva Cardioangiol 1997; 45: 369-75.
9. Meignan M, Rosso J, Gauthier H, Brunengo F, Claudel S, Sagnard L, d'Azemar P, Simonneau G, Charbonnier B. Systematic lung scans reveal a high frequency of silent pulmonary embolism in patients with proximal deep venous thrombosis. Arch Intern Med 2000; 160: 159-64.
10. Monreal M, Ruiz J, Fraile M, Bonet M, Davant E, Muchart J, Vallejos V. Prospective study on the usefulness of lung scan in patients with deep vein thrombosis of the lower limbs. Thromb Haemost 2001; 85: 771-4.
11. Monreal M, Büller H, Lensing AW, Bonet M, Roncales J, Muchart J, Fraile M. Should patients with deep vein thrombosis alone be treated as those with concomitant asymptomatic pulmonary embolism? A prospective study Thromb Haemost 2002; 88: 938-42.
12. Jiménez D, Díaz G, Marín E, Vidal R, Sueiro A, Yusen RD. The risk of recurrent venous thromboembolism in patients with unprovoked symptomatic deep vein thrombosis and asymptomatic pulmonary embolism. Thromb Haemost 2006; 95: 562-6.
13. Jünger M, Diehm C, Störiko H, Hach-Wunderle V, Heidrich H, Karasch T, Ochs HR, Ranft J, Sannwald GA, Strölin A, Janssen D. Mobilization versus immobilization in the treatment of acute proximal deep venous thrombosis: a prospective, randomized, open, multicentre trial. Curr Med Res Opin 2006; 22: 593-602.
14. Stein PD, Matta F, Musani MH, Diaczok B. Silent pulmonary embolism in patients with deep venous thrombosis: a systematic review. Am J Med 2010; 123: 426-31.
15. Ahmad N, Srinivasan K, Moudgil H. Looking for asymptomatic pulmonary embolism in patients with deep vein thrombosis: is it the right practice? Am J Med 2011; 124: e15-7.
16. Sommers BD. Routine screening for silent pulmonary embolism is harmful and unnecessary. Am J Med 2010; 123: e15-7.
17. Arcelus JI, Caprini JA, Monreal M, Suárez C, González-Fajardo J. The management and outcome of acute venous thromboembolism: a prospective registry including 4011 patients. J Vasc Surg 2003; 38: 916-22.
18. Laporte S, Mismetti P, Décousus H, Uresandi F, Otero R, Lobo JL, Monreal M. Clinical predictors for fatal pulmonary embolism in 15520 patients with venous thromboembolism; Findings from the registro informatizado de la enfermedad tromboembólica venosa (RIETE) Registry. Circulation 2008; 117: 1711-6.
19. Monreal M, Munoz-Torrero JF, Naraine VS, Jiménez D, Soler S, Rabuñal R, Gallego P. Pulmonary embolism in patients with chronic obstructive pulmonary disease or congestive heart failure. Am J Med 2006; 119: 851-8.
20. Ruíz-Giménez N, Suárez C, González R, Nieto JA, Todolí JA, Samperiz AL, Monreal M. Predictive variables for major bleeding events in patients presenting with documented acute venous thromboembolism. Findings from the RIETE Registry. Thromb Haemost 2008; 100: 26-31.