Impacts of age and gender on bone marrow profiles of BMP7, BMPRs and Stro-1 + cells in patients with total hip replacement

International Orthopaedics

Volumn 36, Issue 4, 2012, Pages 879-886

  Shen, Yi ^a   Wang, Weili ^a   Li, Xiaomiao ^a   Liu, Zude ^a   Markel, David C ^b   Ren, Weiping ^b,c  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b DETROIT MEDICAL CENTER   (United States)

^c Wayne State University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN RECEPTOR; BONE MORPHOGENETIC PROTEIN RECEPTOR 1A; BONE MORPHOGENETIC PROTEIN RECEPTOR 2; CELL SURFACE PROTEIN; OSTEOGENIC PROTEIN 1; STRO 1 PROTEIN; UNCLASSIFIED DRUG;

ADULT; AGE; AGED; ARTICLE; BONE MARROW BIOPSY; BONE MARROW CELL; BONE MARROW EXAMINATION; CELL COUNT; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; SEX DIFFERENCE; TOTAL HIP PROSTHESIS;

AGE FACTORS; AGED; AGED, 80 AND OVER; ANTIGENS, SURFACE; ARTHROPLASTY, REPLACEMENT, HIP; BONE MARROW CELLS; BONE MORPHOGENETIC PROTEIN 7; BONE MORPHOGENETIC PROTEIN RECEPTORS; CELL COUNT; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; HUMANS; MALE; MIDDLE AGED;

EID: 84859157006     PISSN: 03412695     EISSN: 14325195     Source Type: Journal    
DOI: 10.1007/s00264-011-1370-z     Document Type: Article

References (40)

1. Yamada H, Yoshihara Y, Henmi O, Morita M, Shiromoto Y, Kawano T, Kanaji A, Ando K, Nakagawa M, Kosaki N, Fukaya E (2009) Cementless total hip replacement: past, present, and future. J Orthop Sci 14:228-241
2. Yan MN, Dai KR, Tang TT, Zhu ZA, Lou JR (2010) Reconstruction of peri-implant bone defects using impacted bone allograft and BMP-2 gene-modified bone marrow stromal cells. J Biomed Mater Res A 93:304-313
3. Sumner DR, Turner TM, Urban RM, Virdi AS, Inoue N (2006) Additive enhancement of implant fixation following combined treatment with rhTGF-beta2 and rhBMP-2 in a canine model. J Bone Jt Surg Am 88:806-817
4. Gurkan UA, Gargac J, Akkus O (2010) The sequential production profiles of growth factors and their relations to bone volume in ossifying bone marrow explants. Tissue Eng Part A 16:2295-2306
5. Service RF (2000) Tissue engineers build new bone. Science 289:1498-1500
6. Zannettino AC, Paton S, Kortesidis A, Khor F, Itescu S, Gronthos S (2007) Human mulipotential mesenchymal/stromal stem cells are derived from a discrete subpopulation of STRO-1bright/CD34 /CD45(-)/glycophorin-A-bone marrow cells. Haematologica 92:1707-1708 (Pubitemid 350248254)
7. White AP, Vaccaro AR, Hall JA, Whang PG, Friel BC, McKee MD (2007) Clinical applications of BMP-7/OP-1 in fractures, nonunions and spinal fusion. Int Orthop 31:735-741 (Pubitemid 350160312)
8. Byers RJ, Brown J, Brandwood C, Wood P, Staley W, Hainey L, Freemont AJ, Hoyland JA (1999) Osteoblastic differentiation and mRNA analysis of STRO-1-positive human bone marrow stromal cells using primary in vitro culture and poly (A) PCR. J Pathol 187:374-381 (Pubitemid 29064166)
9. Brusnahan SK, McGuire TR, Jackson JD, Lane JT, Garvin KL, O'Kane BJ, Berger AM, Tuljapurkar SR, Kessinger MA, Sharp JG (2010) Human blood and marrow side population stem cell and Stro-1 positive bone marrow stromal cell numbers decline with age, with an increase in quality of surviving stem cells: correlation with cytokines. Mech Ageing Dev 131:718-722
10. Lane JM (2001) BMPs: why are they not in everyday use? J Bone Jt Surg Am 83-A(Suppl 1):S161-S163
11. Imamura T, Maeda S, Hayashi M (2006) Regulation of BMP signaling. Clin Calcium 16:738-744
12. Mishina Y, Starbuck MW, Gentile MA, Fukuda T, Kasparcova V, Seedor JG, Hanks MC, Amling M, Pinero GJ, Harada S, Behringer RR (2004) Bone morphogenetic protein type IA receptor signaling regulates postnatal osteoblast function and bone remodeling. J Biol Chem 279:27560-27566 (Pubitemid 38812597)
13. Chen TL, Shen WJ, Kraemer FB (2001) Human BMP-7/OP-1 induces the growth and differentiation of adipocytes and osteoblasts in bone marrow stromal cell cultures. J Cell Biochem 82:187-199 (Pubitemid 32606283)
14. Dimitriou R, Dahabreh Z, Katsoulis E, Matthews SJ, Branfoot T, Giannoudis PV (2005) Application of recombinant BMP-7 on persistent upper and lower limb non-unions. Injury 36(Suppl 4): S51-S59 (Pubitemid 41608591)
15. Lissenberg-Thunnissen SN, de Gorter DJ, Sier CF, Schipper IB (2011) Use and efficacy of bone morphogenetic proteins in fracture healing. Int Orthop 35:1271-1280
16. Nicodemo A, Capella M, Deregibus M, Masse A (2011) Nonunion of a sacral fracture refractory to bone grafting: internal fixation and osteogenic protein-1 (BMP-7) application. Musculoskelet Surg 95:151-161
17. Kanakaris NK, Lasanianos N, Calori GM, Verdonk R, Blokhuis TJ, Cherubino P, De BP, Giannoudis PV (2009) Application of bone morphogenetic proteins to femoral non-unions: a 4-year multicentre experience. Injury 40(Suppl 3):S54-S61
18. Robertsson O, Knutson K, Lewold S, Lidgren L (2001) The Swedish Knee Arthroplasty Register 1975-1997: an update with special emphasis on 41,223 knees operated on in 1988-1997. Acta Orthop Scand 72:503-513 (Pubitemid 33043591)
19. Furnes O, Espehaug B, Lie SA, Vollset SE, Engesaeter LB, Havelin LI (2002) Early failures among 7,174 primary total knee replacements: a follow-up study from the Norwegian Arthroplasty Register 1994-2000. Acta Orthop Scand 73:117-129
20. Vazquez-Vela JG, Worland RL, Keenan J, Norambuena N (2003) Patient demographics as a predictor of the ten-year survival rate in primary total knee replacement. J Bone Jt Surg Br 85:52-56 (Pubitemid 36193043)
21. Fortin PR, Penrod JR, Clarke AE, St Pierre Y, Joseph L, Belisle P, LiangMH, Ferland D, Phillips CB, Mahomed N et al (2002) Timing of total joint replacement affects clinical outcomes among patients with osteoarthritis of the hip or knee. Arthritis Rheum 46:3327-3330 (Pubitemid 35453544)
22. Simmons PJ, Torok-Storb B (1991) Identification of stromal cell precursors in human bone marrow by a novel monoclonal antibody, STRO-1. Blood 78:55-62
23. Fan W, Crawford R, Xiao Y (2008) Structural and cellular differences between metaphyseal and diaphyseal periosteum in different aged rats. Bone 42:81-89 (Pubitemid 350297182)
24. Giurea A, Ruger BM, Hollemann D, Yanagida G, Kotz R, Fischer MB (2006) STRO-1+ mesenchymal precursor cells located in synovial surface projections of patients with osteoarthritis. Osteoarthr Cartil 14:938-943 (Pubitemid 44138666)
25. Grogan SP, Miyaki S, Asahara H, D'Lima DD, Lotz MK (2009) Mesenchymal progenitor cell markers in human articular cartilage: normal distribution and changes in osteoarthritis. Arthritis Res Ther 11:R85
26. Chan GK, Duque G (2002) Age-related bone loss: old bone, new facts. Gerontology 48:62-71 (Pubitemid 34195721)
27. Quarto R, Thomas D, Liang CT (1995) Bone progenitor cell deficits and the age-associated decline in bone repair capacity. Calcif Tissue Int 56:123-129
28. Murphy JM, Dixon K, Beck S, Fabian D, Feldman A, Barry F (2002) Reduced chondrogenic and adipogenic activity of mesenchymal stem cells from patients with advanced osteoarthritis. Arthritis Rheum 46:704-713 (Pubitemid 34218142)
29. Leskela HV, Risteli J, Niskanen S, Koivunen J, Ivaska KK, Lehenkari P (2003) Osteoblast recruitment from stem cells does not decrease by age at late adulthood. Biochem Biophys Res Commun 311:1008-1013 (Pubitemid 37393419)
30. De BC, Dell'Accio F, Luyten FP (2001) Human periosteumderived cells maintain phenotypic stability and chondrogenic potential throughout expansion regardless of donor age. Arthritis Rheum 44:85-95
31. Bishop GB, Einhorn TA (2007) Current and future clinical applications of bone morphogenetic proteins in orthopaedic trauma surgery. Int Orthop 31:721-727 (Pubitemid 350160314)
32. Lavery KS, Swain PM, Falb D, Aoui-Ismaili MH (2008) BMP-2/4 and BMP-6/7 differentially utilize cell surface receptors to induce osteoblastic differentiation of human bone marrow derived mesenchymal stem cells. J Biol Chem 283:20948-20958
33. Fayaz HC, Giannoudis PV, Vrahas MS, Smith RM, Moran C, Pape HC, Krettek C, Jupiter JB (2011) The role of stem cells in fracture healing and nonunion. Int Orthop. 2011 Aug 24. [Epub ahead of print]
34. Ivkovic A, Marijanovic I, Hudetz D, Porter MR, Pecina M, Evans HCh (2011) Regenerative medicine and tissue engineering in orthopaedic surgery. Front Biosci E3:923-944
35. Ma T, Nelson ER, Mawatari T, Oh KJ, Larsen DM, Smith RL, Goodman SB (2006) Effects of local infusion of OP-1 on particleinduced and NSAID-induced inhibition of bone ingrowth in vivo. J Biomed Mater Res A 79:740-746 (Pubitemid 44845190)
36. Friedlaender GE, Perry CR, Cole JD, Cook SD, Cierny G, Muschler GF, Zych GA, Calhoun JH, LaForte AJ, Yin S (2001) Osteogenic protein-1 (bone morphogenetic protein-7) in the treatment of tibial nonunions. J Bone Jt Surg Am 83-A(Suppl 1):S151-S158
37. Shah AK, Lazatin J, Sinha RK, Lennox T, Hickok NJ, Tuan RS (1999) Mechanism of BMP-2 stimulated adhesion of osteoblastic cells to titanium alloy. Biol Cell 91:131-142 (Pubitemid 129672797)
38. Osyczka AM, mek-Poprawa M, Wojtowicz A, Akintoye SO (2009) Age and skeletal sites affect BMP-2 responsiveness of human bone marrow stromal cells. Connect Tissue Res 50:270-277
39. Lallier TE, Spencer A (2007) Use of microarrays to find novel regulators of periodontal ligament fibroblast differentiation. Cell Tissue Res 327:93-109 (Pubitemid 44833053)
40. McCann RM (2010) Body mass index is more predictive of progenitor number in bone marrow stromal cell population than age in men: expanding the predictors of the progenitor compartment. Tissue Eng 16:889-896