The effect of exogenous apelin on the secretion of pancreatic juice in anaesthetized rats

Journal of Physiology and Pharmacology

Volumn 63, Issue 1, 2012, Pages 53-60

  Kapica, M ^a   Jankowska, A ^b   Antushevich, H ^b   Pietrzak, P ^c,d   Bierla, J B ^c,d   Dembinski, A ^e   Zabielski, R ^c  

^a UNIVERSITY OF LIFE SCIENCES IN LUBLIN   (Poland)

^b KIELANOWSKI INSTITUTE OF ANIMAL PHYSIOLOGY AND NUTRITION   (Poland)

^c WARSAW UNIVERSITY OF LIFE SCIENCES   (Poland)

^d MEDICAL UNIVERSITY OF WARSAW   (Poland)

^e JAGIELLONIAN UNIVERSITY MEDICAL COLLEGE   (Poland)

Author keywords

Acinar cells; Apelin; Capsaicin; Cholecystokinin; Pancreas; Pancreatic blood flow; Regulation; Vagotomy

Indexed keywords

AMYLASE; APELIN; APELIN RECEPTOR; CAPSAICIN; CHOLECYSTOKININ; TARAZEPIDE; TRYPSIN;

ACINAR CELL; AMYLASE RELEASE; ANESTHESIA; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; IMMUNOFLUORESCENCE; LASER DOPPLER FLOWMETRY; MALE; NONHUMAN; PANCREAS BLOOD FLOW; PANCREAS DUCT; PANCREAS ISLET CELL; PANCREAS JUICE; RAT; VAGOTOMY; VAGUS NERVE;

ACINAR CELLS; AMYLASES; ANIMALS; CHOLECYSTOKININ; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; ISLETS OF LANGERHANS; MALE; PANCREAS, EXOCRINE; PANCREATIC DUCTS; PANCREATIC JUICE; RATS; RATS, WISTAR; RECEPTORS, G-PROTEIN-COUPLED; SECRETORY RATE; SINCALIDE; VAGUS NERVE;

EID: 84859141366     PISSN: 08675910     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (29)

1. Tatemoto K, Hosoya M, Habata Y, et al. Isolation and characterization of a novel endogenous peptide ligand for the human APJ receptor. Biochem Biophys Res Commun 1998; 251: 471-476.
2. Habata Y, Fujii R, Hosoya M, et al. Apelin, the natural ligand of the orphan receptor APJ, is abundantly secreted in the colostrum. Biochim Biophys Acta 1999; 1452: 25-35.
3. O'Carroll AM, Selby TL, Palkovits M, Lolait SJ. Distribution of mRNA encoding B78/apj, the rat homologue of the human APJ receptor, and its endogenous ligand apelin in brain and peripheral tissues. Biochim Biophys Acta 2000; 1492: 72-80.
4. Wang G, Anini Y, Wei W, et al. Apelin, a new enteric peptide: localization in the gastrointestinal tract, ontogeny, and stimulation of gastric cell proliferation and of cholecystokinin secretion. Endocrinology 2004; 145: 1342-1348.
5. Heinonen MV, Purhonen AK, Miettinen P, et al. Apelin, orexin-A and leptin plasma levels in morbid obesity and effect of gastric banding. Regul Pept 2005; 130: 7-13.
6. Lee DK, Cheng R, Nguyen T, et al. Characterization of apelin, the ligand for the APJ receptor. J Neurochem 2000; 74: 34-41.
7. Edinger AL, Hoffman TL, Sharron M, et al. An orphan seven-transmembrane domain receptor expressed widely in the brain functions as a coreceptor for human immunodeficiency virus type 1 and simian immunodeficiency virus. J Virol 1998; 72: 7934-7940.
8. Hosoya M, Kawamata Y, Fukusumi S, et al. Molecular and functional characteristics of APJ. Tissue distribution of mRNA and interaction with the endogenous ligand apelin. J Biol Chem 2000; 275: 21061-21067.
9. Taheri S, Murphy K, Cohen M, et al. The effects of centrally administered apelin-13 on food intake, water intake and pituitary hormone release in rats. Biochem Biophys Res Commun 2002; 291: 1208-1212.
10. Boucher J, Masri B, Daviaud D, et al. Apelin, a newly identified adipokine up-regulated by insulin and obesity. Endocrinology 2005; 146: 1764-1771.
11. Lau T, Carlsson P-O, Leung PS. Evidence for a local angiotensin-generating system and dose-dependent inhibition of glucose-stimulated insulin release by angiotensin II in isolated pancreatic islets. Diabetologia 2004; 47: 240-248.
12. Sorhede Winzell M, Magnusson C, Ahren B. The apj receptor is expressed in pancreatic islets and its ligandapelin, inhibits insulin secretion in mice. Regul Pept 2005; 131: 12-17.
13. Susaki E, Wang G, Cao G, Wang HQ, Englander EW, Greeley GH Jr. Apelin cells in the rat stomach. Regul Pept 2005; 129: 37-41.
14. Tatemoto K. Search for an endogenous ligand of the orphan G proteincoupled receptor-discovery of apelin, a novel biologically active peptide. Nippon Rinsho 2000; 58: 737-746.
15. Sobhani I, Buyse M, Goiot H, et al. Vagal stimulation rapidly increases leptin secretion in human stomach. Gastroenterology 2002; 122: 259-263.
16. Guilmeau S, Buyse M, Tsocas A, Laigneau JP, Bado A. Duodenal leptin stimulates cholecystokinin secretion: evidence for a positive leptin-CCK feedback loop. Diabetes 2003; 52: 1664-1672.
17. Kapica M, Laubitz D, Puzio I, Lubanska A, Zabielski R. The ghrelin pentapeptide inhibits the secretion of pancreatic juice in rats. J Physiol Pharmacol 2006; 54(Suppl. 3): 691-700.
18. Nawrot-Porabka K, Jaworek J, Leja-Szpak A, et al. The effect of luminal ghrelin on pancreatic enzyme secretion in the rat. Regul Pept 2007; 143: 56-63.
19. Kapica M, Zabielska M, Puzio I, et al. Obestatin stimulates the secretion of pancreatic juice enzymes through a vagal pathway in anaesthetized rats - preliminary results. J Physiol Pharmacol 2007; 58(Suppl. 3): 123-130.
20. Zabielski R, Lesniewska V, Borlak J, Gregory PC, et al. Effects of intraduodenal administration of tarazepide on pancreatic secretion and duodenal EMG in neonatal calves. Regul Pept 1998, 78: 113-123.
21. Jaworek J, Nawrot-Porabka K, Leja-Szpak A, Konturek SJ. Brain-gut axis in the modulation of pancreatic enzyme secretion. J Physiol Pharmacol 2010; 61: 523-531.
22. Williams JA, Korc M, Dormer RL. Action of secretagogues on a new preparation of functionally intact, isolated pancreatic acini. Am J Physiol 1978; 235: 517-524.
23. Konturek SJ, Szlachcic A, Dembinski A, Warzecha Z, Jaworek J, Stachura J. Nitric oxide in pancreatic secretion and hormone-induced pancreatitis in rats. Int J Pancreatol 1994; 15: 19-28.
24. Flemstrom G, Makela K, Purhonen AK, et al. Apelin stimulation of duodenal bicarbonate secretion: feeding-dependent and mediated via apelin-induced release of enteric cholecystokinin. Acta Physiol 2011; 201: 141-150.
25. Tatemoto K, Takayama K, Zou M-X, et al. The novel peptide apelin lowers blood pressure via a nitric oxide-dependent mechanism. Regul Pept 2001; 99: 87-92.
26. Szczepanska-Sadowska E, Cudnoch-Jedrzejewska A, Ufnal M, et al. Brain and cardiovascular diseases: common neurogenic background of cardiovascular, metabolic and inflammatory diseases. J Physiol Pharmacol 2010; 61: 509-521.
27. Wang G, Kundu R, Han S, et al. Ontogeny of apelin and its receptor in the rodent gastrointestinal tract. Regul Pept 2009; 158: 32-39.
28. Medhurst AD, Jennings CA, Robbins MJ, et al. Pharmacological and immunohistochemical characterization of the APJ receptor and its endogenous ligand apelin. J Neurochem 2003; 84: 1162-1172.
29. Ringstrom C, Nitert MD, Bennet H, et al. Apelin is a novel islet peptide. Regul Pept 2010; 162: 44-51.