Bul proteins, a nonredundant, antagonistic family of ubiquitin ligase regulatory proteins

Eukaryotic Cell

Volumn 11, Issue 4, 2012, Pages 463-470

  Novoselova, Tatiana V ^a   Zahira, Kiran ^a   Rose, Ruth Sarah ^a   Sullivan, James A ^a  

^a QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID TRANSPORTER; CAN1 PROTEIN, S CEREVISIAE; CATION TRANSPORT PROTEIN; ESCRT PROTEIN; GAP1 PROTEIN, S CEREVISIAE; HYBRID PROTEIN; MEMBRANE PROTEIN; RSP5 PROTEIN, S CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEIN; SIGNAL TRANSDUCING ADAPTOR PROTEIN; SMF1 PROTEIN, S CEREVISIAE; UBIQUITIN PROTEIN LIGASE;

ARTICLE; GENE INACTIVATION; GENETICS; METABOLISM; MICROBIAL VIABILITY; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN TRANSPORT; SACCHAROMYCES CEREVISIAE; SEQUENCE HOMOLOGY;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AMINO ACID TRANSPORT SYSTEMS; AMINO ACID TRANSPORT SYSTEMS, BASIC; CATION TRANSPORT PROTEINS; ENDOSOMAL SORTING COMPLEXES REQUIRED FOR TRANSPORT; GENE KNOCKOUT TECHNIQUES; MEMBRANE PROTEINS; MICROBIAL VIABILITY; PROTEIN BINDING; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN TRANSPORT; RECOMBINANT FUSION PROTEINS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; UBIQUITIN-PROTEIN LIGASE COMPLEXES; UBIQUITIN-PROTEIN LIGASES;

SACCHAROMYCES CEREVISIAE;

EID: 84859128614     PISSN: 15359778     EISSN: None     Source Type: Journal    
DOI: 10.1128/EC.00009-12     Document Type: Article

References (36)

1. Auty R, et al. 2004. Purification of active TFIID from Saccharomyces cerevisiae. Extensive promoter contacts and co-activator function. J. Biol. Chem. 279:49973-49981.
2. Bernassola F, Karin M, Ciechanover A, Melino G. 2008. The HECT family of E3 ubiquitin ligases: multiple players in cancer development. Cancer Cell 14:10-21.
3. Bilsland E, Hult M, Bell S, Sunnerhagen P, Downs J. 2007. The Bre5/ Ubp3 ubiquitin protease complex from budding yeast contributes to the cellular response to DNA damage. DNA Repair 6:1471-1484.
4. Clague M, Urbé S. 2006. Endocytosis: the DUB version. Trends Cell Biol. 16:551-559.
5. Cohen M, Stutz F, Belgareh N, Haguenauer-Tsapis R, Dargemont C. 2003. Ubp3 requires a cofactor, Bre5, to specifically de-ubiquitinate the COPII protein, Sec23. Nat. Cell Biol. 5:661-667.
6. David Y, Ziv T, Admon A, Navon A. 2010. The E2 ubiquitin conjugating enzymes direct polyubiquitination to preferred lysines. J. Biol. Chem. 285: 8595-8604.
7. Deshaies R, Joazeiro C. 2009. RING domain E3 ubiquitin ligases. Annu. Rev. Biochem. 78:399-434.
8. Devasahayam G, Burke D, Sturgill T. 2007. Golgi manganese transport is required for rapamycin signaling in Saccharomyces cerevisiae. Genetics 177:231-238.
9. Dunn R, Hicke L. 2001. Multiple roles for Rsp5p-dependent ubiquitination at the internalization step of endocytosis. J. Biol. Chem. 276:25974-25981.
10. Helliwell S, Losko S, Kaiser C. 2001. Components of a ubiquitin ligase complex specify polyubiquitination and intracellular trafficking of the general amino acid permease. J. Cell Biol. 153:649-662.
11. Hettema E, Valdez-Taubas J, Pelham H. 2004. Bsd2 binds the ubiquitin ligase Rsp5 and mediates the ubiquitination of transmembrane proteins. EMBO J. 23:1279-1288.
12. Hiraishi H, Okada M, Ohtsu I, Takagi H. 2009. A functional analysis of the yeast ubiquitin ligase Rsp5: the involvement of the ubiquitinconjugating enzyme Ubc4 and poly-ubiquitination in ethanol-induced down-regulation of targeted proteins. Biosci. Biotechnol. Biochem. 73: 2268-2273.
13. Hoppe T. 2005. Multiubiquitylation by E4 enzymes: 'one size' doesn't fit all. Trends Biochem. Sci. 30:183-187.
14. Hoppe T, et al. 2000. Activation of a membrane-bound transcription factor by regulated ubiquitin/proteasome-dependent processing. Cell 102:577-586.
15. Kanelis V, Bruce M, Skrynnikov N, Rotin D, Forman-Kay J. 2006. Structural determinants for high-affinity binding in a Nedd4 WW3* domain-Comm PY motif complex. Structure 14:543-553.
16. Kee Y, Huibregtse J. 2007. Regulation of catalytic activities of HECT ubiquitin ligases. Biochem. Biophys. Res. Commun. 354:329-333.
17. Kvint K, et al. 2008. Reversal of RNA polymerase II ubiquitylation by the ubiquitin protease Ubp3. Mol. Cell 30:498-506.
18. Léon S, Haguenauer-Tsapis R. 2009. Ubiquitin ligase adaptors: regulators of ubiquitylation and endocytosis of plasma membrane proteins. Exp. Cell Res. 315:1574-1583.
19. Léon S, Erpapazoglou Z, Haguenauer-Tsapis R. 2008. Ear1p and Ssh4p are new adaptors of the ubiquitin ligase Rsp5p for cargo ubiquitylation and sorting at multivesicular bodies. Mol. Biol. Cell 19:2379-2388.
20. Lin CH, Macgurn JA, Chu T, Stefan CJ, Emr SD. 2008. Arrestin-related ubiquitin-ligase adaptors regulate endocytosis and protein turnover at the cell surface. Cell 135:714-725.
21. Liu J, Sitaram A, Burd C. 2007. Regulation of copper-dependent endocytosis and vacuolar degradation of the yeast copper transporter, Ctr1p, by the Rsp5 ubiquitin ligase. Traffic 8:1375-1384.
22. Liu X, Culotta V. 1999. Mutational analysis of Saccharomyces cerevisiae Smf1p, a member of the Nramp family of metal transporters. J. Mol. Biol. 289:885-891.
23. Namy O, et al. 2003. Identification of stop codon readthrough genes in Saccharomyces cerevisiae. Nucleic Acids Res. 31:2289-2296.
24. Navon A, Ciechanover A. 2009. The 26 S proteasome: from basic mechanisms to drug targeting. J. Biol. Chem. 284:33713-33718.
25. Nikko E, Pelham H. 2009. Arrestin-mediated endocytosis of yeast plasma membrane transporters. Traffic 10:1856-1867.
26. Nikko E, Sullivan J, Pelham H. 2008. Arrestin-like proteins mediate ubiquitination and endocytosis of the yeast metal transporter Smf1. EMBO Rep. 9:1216-1221.
27. Pickart C. 2004. Back to the future with ubiquitin. Cell 116:181-190.
28. Rape M, et al. 2001. Mobilization of processed, membrane-tethered SPT23 transcription factor by CDC48(UFD1/NPL4), a ubiquitin-selective chaperone. Cell 107:667-677.
29. Shearwin-Whyatt L, Dalton H, Foot N, Kumar S. 2006. Regulation of functional diversity within the Nedd4 family by accessory and adaptor proteins. BioEssays 28:617-628.
30. Slagsvold T, Pattni K, Malerød L, Stenmark H. 2006. Endosomal and non-endosomal functions of ESCRT proteins. Trends Cell Biol. 16:317-326.
31. Soetens O, De Craene JO, Andre B. 2001. Ubiquitin is required for sorting to the vacuole of the yeast general amino acid permease, Gap1. J. Biol. Chem. 276:43949-43957.
32. Stimpson H, Lewis M, Pelham H. 2006. Transferrin receptor-like proteins control the degradation of a yeast metal transporter. EMBO J. 25: 662-672.
33. Sullivan J, Lewis M, Nikko E, Pelham H. 2007. Multiple interactions drive adaptor-mediated recruitment of the ubiquitin ligase rsp5 to membrane proteins in vivo and in vitro. Mol. Biol. Cell 18:2429-2440.
34. Welchman R, Gordon C, Mayer R. 2005. Ubiquitin and ubiquitin-like proteins as multifunctional signals. Nat. Rev. Mol. Cell. Biol. 6:599-609.
35. Yashiroda H, Oguchi T, Yasuda Y, Toh-EA, Kikuchi Y. 1996. Bul1, a new protein that binds to the Rsp5 ubiquitin ligase in Saccharomyces cerevisiae. Mol. Cell. Biol. 16:3255-3263.
36. Yashiroda H, Kaida D, Toh-e A, Kikuchi Y. 1998. The PY motif of Bul1 protein is essential for growth of Saccharomyces cerevisiae under various stress conditions. Gene 225:39-46.