Melatonin suppresses aromatase expression and activity in breast cancer associated fibroblasts

Breast Cancer Research and Treatment

Volumn 132, Issue 2, 2012, Pages 765-771

  Knower, Kevin C ^a   To, Sarah Q ^a   Takagi, Kiyoshi ^b   Miki, Yasuhiro ^b   Sasano, Hironobu ^b   Simpson, Evan R ^a,c   Clyne, Colin D ^a,c  

^a HUDSON INSTITUTE OF MEDICAL RESEARCH   (Australia)

^b TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c MONASH UNIVERSITY   (Australia)

Author keywords

Aromatase; Breast cancer; Epigenetic; Melatonin; Postmenopause; Prostaglandin E 2

Indexed keywords

AROMATASE; G PROTEIN COUPLED RECEPTOR; MELATONIN; MESSENGER RNA; PROSTAGLANDIN E2;

ARTICLE; BREAST CANCER; CONTROLLED STUDY; CYP19A1 GENE; EPIGENETICS; FIBROBLAST; GENE EXPRESSION; GENE REPRESSION; GENETIC TRANSCRIPTION; HORMONE ACTION; HORMONE SYNTHESIS; HUMAN; HUMAN CELL; HUMAN TISSUE; MTNR1A GENE; MTNR1B GENE; ONCOGENE; PRIORITY JOURNAL; PROMOTER REGION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ADIPOSE TISSUE; AROMATASE; BREAST NEOPLASMS; CARCINOMA, DUCTAL, BREAST; CELLS, CULTURED; DINOPROSTONE; DOWN-REGULATION; FEMALE; FIBROBLASTS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MELATONIN; POLYMERASE CHAIN REACTION; PROMOTER REGIONS, GENETIC; RECEPTOR, MELATONIN, MT1; RECEPTOR, MELATONIN, MT2; RECEPTORS, ESTROGEN; RNA, MESSENGER; TRANSCRIPTION, GENETIC;

EID: 84859107599     PISSN: 01676806     EISSN: 15737217     Source Type: Journal    
DOI: 10.1007/s10549-012-1953-4     Document Type: Article

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