Viral shedding of 2009 pandemic H1N1 and evaluation of quarantine Recommendations

Japanese Journal of Infectious Diseases

Volumn 65, Issue 2, 2012, Pages 105-110

  Chin, Bum Sik ^a   Chae, Yun Tae ^a   Choi, Hee Kyung ^a   Baek, Ji Hyeon ^a   Jin, Sung Joon ^a   Shin, So Youn ^a   Han, Sang Hoon ^a   Choi, Jun Yong ^a   Kim, Chang Oh ^a   Song, Young Goo ^a   Jeong, Seok Hoon ^a   Kim, June Myung ^a  

^a Yonsei University College of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

VIRUS RNA;

2009 H1N1 INFLUENZA; ADULT; AGED; ARTICLE; CLINICAL ARTICLE; COMORBIDITY; CONTROLLED STUDY; FEMALE; HOSPITAL PATIENT; HUMAN; INFECTION CONTROL; KOREA; MALE; PANDEMIC INFLUENZA; PROSPECTIVE STUDY; PUBLIC HEALTH; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RISK FACTOR; SYMPTOMATOLOGY; TERTIARY HEALTH CARE; VIRUS ISOLATION; VIRUS LOAD; VIRUS SHEDDING;

ADULT; AGED; AGED, 80 AND OVER; FEMALE; HUMANS; INFLUENZA A VIRUS, H1N1 SUBTYPE; INFLUENZA, HUMAN; LONGITUDINAL STUDIES; MALE; MIDDLE AGED; OROPHARYNX; QUARANTINE; REAL-TIME POLYMERASE CHAIN REACTION; TIME FACTORS; VIRAL LOAD; VIRUS SHEDDING;

EID: 84859099036     PISSN: 13446304     EISSN: 18842836     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. World Health Organization: World Now at the Start of 2009 Influenza Pandemic. Statement to the press by WHO Director- General Dr. Margaret Chan, 11 June 2009. Online at http://www.who.int/mediacentre/news/statements/2009/h1n1_pandemic_phase6_20090611/en/index.html. Accessed on 15 March 2010.
2. Korea Centers for Disease, Control and Prevention (2010): Current status of selected infectious diseases. Public Health Wkly. Rep., 3, 30-35.
3. Centers for Disease Control and Prevention (2010): Update: influenza activity-United States, August 30, 2009-January 9, 2010. Morbid. Mortal. Wkly. Rep., 59, 38-43.
4. Hancock, K., Veguilla, V., Lu, X., et al. (2009): Cross-reactive antibody responses to the 2009 pandemic H1N1 influenza virus. N. Engl. J. Med., 361, 1945-1952.
5. Centers for Disease Control and Prevention (2009): Serum crossreactive antibody response to a novel influenza A (H1N1) virus after vaccination with seasonal influenza vaccine. Morbid. Mortal. Wkly. Rep., 58, 521-524.
6. To, K.K.W., Hung, I.F.N., Li, I.W.S., et al. (2010): Delayed clearance of viral load and marked cytokine activation in severe cases of pandemic H1N1 2009 influenza virus infection. Clin. Infect. Dis., 50, 850-859.
7. Witkop, C.T., Duffy, M.R., Macias, E.A., et al. (2010): Novel influenza A (H1N1) outbreak at the U.S. Air Force Academy: epidemiology and viral shedding duration. Am. J. Prev. Med., 38, 121-126.
8. To, K.K., Chan, K.H., Li, I.W., et al. (2010): Viral load in patients infected with pandemic H1N1 2009 influenza A virus. J. Med. Virol., 82, 1-7.
9. Li, I.W., Hung, I.F., To, K.K., et al. (2010): The natural viral load profile of patients with pandemic 2009 influenza A(H1N1) and the effect of oseltamivir treatment. Chest, 137, 759-768.
10. Charlier, C., Enouf, V., Lanternier, F., et al. (2009): Kinetics of nasopharyngeal shedding of novel H1N1 (swine-like) influenza A virus in an immunocompetent adult under oseltamivir therapy. Clin. Microbiol. Infect., 15, 1189-1191.
11. Centers for Disease Control and Prevention (2010): Interim Guidance on Infection Control Measures for 2009 H1N1 Influenza in Healthcare Settings, including Protection of Healthcare Personnel. Online at http://www.cdc.gov/h1n1flu/guidelines_infection_control.htm
12. Lee, N., Chan, P.K., Hui, D.S., et al. (2009): Viral loads and duration of viral shedding in adult patients hospitalized with influenza. J. Infect. Dis., 200, 492-500.
13. Dulek, D.E., Williams, J.V., Creech, C.B., et al. (2010): Use of intravenous zanamivir after development of oseltamivir resistance in a critically ill immunosuppressed child infected with 2009 pandemic influenza A (H1N1) virus. Clin. Infect. Dis., 50, 1493-1496.
14. Mandelboim, M., Hindiyeh, M., Meningher, T., et al. (2010): Possible transmission of pandemic (H1N1) 2009 virus with oseltamivir resistance. Emerg. Infect. Dis., 16, 873-874.
15. Hayden, F.G., Treanor, J.J., Fritz, R.S., et al. (1999): Use of the oral neuraminidase inhibitor oseltamivir in experimental human influenza: randomized controlled trials for prevention and treatment. JAMA, 282, 1240-1246.
16. Leekha, S., Zitterkopf, N.P., Espy, M.J., et al. (2007): Duration of influenza A virus shedding in hospitalized patients and implications for infection control. Infect. Control Hosp. Epidemiol., 28, 1071-1076.
17. Treanor, J.J., Hayden, F.G., Vrooman, P.S., et al. (2000): Efficacy and safety of the oral neuraminidase inhibitor oseltamivir in treating acute influenza: a randomized controlled trial. JAMA, 283, 1016-1024.
18. Nicholson, K.G., Aoki, F.Y., Osterhaus, A., et al. (2000): Efficacy and safety of oseltamivir in treatment of acute influenza: a randomised controlled trial. Lancet, 355, 1845-1850.
19. Boivin, G., Coulombe, Z. and Wat, C. (2003): Quantification of the influenza virus load by real time polymerase chain reaction in nasopharyngeal swabs of patients treated with oseltamivir. J. Infect. Dis., 188, 578-580.
20. Giannella, M., Alonso, M., Garcia de Viedma, D., et al. (2011): Prolonged viral shedding in pandemic influenza A(H1N1): clinical significance and viral load analysis in hospitalized patients. Clin. Microbiol. Infect., 17,1160-1165.
21. Lee, N., Chan, P.K., Wong, C.K., et al. (2011): Viral clearance and inflammatory response patterns in adults hospitalized for pandemic 2009 influenza A(H1N1) virus pneumonia. Antivir. Ther., 16, 237-247.
22. Carrat, F., Vergu, E., Ferguson, N.M., et al. (2008): Time lines of infection and disease in human influenza: a review of volunteer challenge studies. Am. J. Epidemiol., 167, 775-785.
23. Gooskens, J., Jonges, M., Claas, E., et al. (2009): Prolonged influenza virus infection during lymphocytopenia and frequent detection of drug-resistant viruses. J. Infect. Dis., 199, 1435-1441.
24. Chien, Y.S., Su, C.P., Tsai, H.T., et al. (2010): Predictors and outcomes of respiratory failure among hospitalized pneumonia patients with 2009 H1N1 influenza in Taiwan. J. Infect., 60, 168-174.
25. Lee, N., Chan, P.K., Choi, K.W., et al. (2007): Factors associated with early hospital discharge of adult influenza patients. Antivir. Ther., 12, 501-508.
26. Hayden, F.G., Fritz, R., Lobo, M.C., et al. (1998): Local and systemic cytokine responses during experimental human influenza A virus infection. Relation to symptom formation and host defense. J. Clin. Invest., 101, 643-649.
27. Fleury, H., Burrel, S., Balick Weber, C., et al. (2009): Prolonged shedding of influenza A(H1N1) virus: two case reports from France 2009. Euro Surveill., 14.