Development of a novel three-dimensional, automatable and integrated bioprocess for the differentiation of embryonic stem cells into pulmonary alveolar cells in a rotating vessel bioreactor system

Tissue Engineering - Part C: Methods

Volumn 18, Issue 4, 2012, Pages 263-272

  Siti Ismail, Norhayati ^a   Samadikuchaksaraei, Ali ^a   Bishop, Anne E ^a   Polak, Julia M ^a   Mantalaris, Athanasios ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BIOREACTORS; DRUG PRODUCTS; ELECTRON MICROSCOPY; INTEGRATION; STEM CELLS; SURFACE ACTIVE AGENTS; THREE DIMENSIONAL;

A549 CELLS; ACTIVE PROCESS; ALVEOLAR EPITHELIAL CELLS; AQUAPORINS; BIOPROCESSES; BIOPROCESSING; BIOREACTOR SYSTEM; CELL THERAPY; CLINICAL APPLICATION; DIFFERENTIATED CELLS; EMBRYONIC STEM CELLS; EPITHELIAL CELLS; FLASK CULTURE; FLUORESCENT STAINING; GROWTH FACTOR; HIGH REPRODUCIBILITY; IN-VITRO; LOW-YIELD; LOWER COST; MICROSCOPY DEMONSTRATED; MICROVILLI; OPERATOR INTERFERENCE; PULMONARY ALVEOLAR CELLS; SEVERAL PROTOCOLS; SINGLE-STEP; STATIC CONDITIONS; SURFACTANT PROTEINS; TARGET CELLS; TYPE II;

CELL CULTURE;

MURINAE;

ANTIBODY;

ANIMAL; ARTICLE; AUTOMATION; BIOREACTOR; CELL AGGREGATION; CELL DIFFERENTIATION; CELL LINE; CULTURE MEDIUM; CULTURE TECHNIQUE; CYTOLOGY; DRUG EFFECT; EMBRYONIC STEM CELL; HUMAN; IMMOBILIZED CELL; IMMUNOLOGY; INSTRUMENTATION; LUNG ALVEOLUS; METABOLISM; METHODOLOGY; MOUSE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; ROTATION; ULTRASTRUCTURE;

ANIMALS; ANTIBODIES; AUTOMATION; BIOREACTORS; CELL AGGREGATION; CELL CULTURE TECHNIQUES; CELL DIFFERENTIATION; CELL LINE; CELLS, IMMOBILIZED; CULTURE MEDIA, CONDITIONED; EMBRYONIC STEM CELLS; HUMANS; MICE; PULMONARY ALVEOLI; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; ROTATION;

EID: 84859053927     PISSN: 19373384     EISSN: 19373392     Source Type: Journal    
DOI: 10.1089/ten.tec.2011.0299     Document Type: Article

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