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Volumn 8, Issue 1, 2012, Pages 1-6

Identification of novel variant of EML4-ALK fusion gene in NSCLC: Potential benefits of the RT-PCR method

Author keywords

ALK inhibitors; EML4 ALK rearrangement; EML4 ALK variants; NSCLC

Indexed keywords

ANAPLASTIC LYMPHOMA KINASE; ANAPLASTIC LYMPHOMA KINASE INHIBITOR; ECHINODERM MICROTUBULE ASSOCIATED PROTEIN LIKE 4; PROTEIN; PROTEIN TYROSINE KINASE INHIBITOR; RNA; UNCLASSIFIED DRUG;

EID: 84859044774     PISSN: 15509702     EISSN: 15552810     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (12)

References (9)
  • 1
    • 34547638047 scopus 로고    scopus 로고
    • Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer
    • Soda M, Choi YL, Enomoto M, et al. Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer. Nature. 2007; 448: 562-565.
    • (2007) Nature , vol.448 , pp. 562-565
    • Soda, M.1    Choi, Y.L.2    Enomoto, M.3
  • 3
    • 79954592031 scopus 로고    scopus 로고
    • Role of ERK-BIM and STAT3-Survivin Signaling Pathways in ALK Inhibitor-Induced Apoptosis in EML4-ALK-Positive Lung Cancer
    • Takezawa K, Okamoto I, Nishio K, Jänne PA, et al. Role of ERK-BIM and STAT3-Survivin Signaling Pathways in ALK Inhibitor-Induced Apoptosis in EML4-ALK-Positive Lung Cancer. Clinical Cancer Research. 2011; 17: 2140.
    • (2011) Clinical Cancer Research , vol.17 , pp. 2140
    • Takezawa, K.1    Okamoto, I.2    Nishio, K.3    Jänne, P.A.4
  • 4
  • 5
    • 79955656623 scopus 로고    scopus 로고
    • Exon scanning by reverse transcriptase- polymerase chain reaction for detection of known and novel EML4-ALK fusion variants in non-small cell lung cancer
    • Sanders HR, Li HR, Bruey J-M, et al. Exon scanning by reverse transcriptase- polymerase chain reaction for detection of known and novel EML4-ALK fusion variants in non-small cell lung cancer. Cancer Genetics. 2011; 204: 46-51.
    • (2011) Cancer Genetics , vol.204 , pp. 46-51
    • Sanders, H.R.1    Li, H.R.2    Bruey, J.-M.3
  • 6
    • 48549098388 scopus 로고    scopus 로고
    • Identification of Novel Isoforms of the EML4-ALK Transforming Gene in Non-Small Cell Lung Cancer
    • 4972-4922
    • Choi YL, Takeuchi K, Soda M, et al. Identification of Novel Isoforms of the EML4-ALK Transforming Gene in Non-Small Cell Lung Cancer. Cancer Research. 2008; 68: 4972-4922.
    • (2008) Cancer Research , vol.68
    • Choi, Y.L.1    Takeuchi, K.2    Soda, M.3
  • 7
    • 77954399760 scopus 로고    scopus 로고
    • Fusion of EML4 and ALK is associated with development of lung adenocarcinomas lacking EGFR and KRAS mutations and is correlated with ALK expression
    • Zhang X, Zhang S, Yang X, et al. Fusion of EML4 and ALK is associated with development of lung adenocarcinomas lacking EGFR and KRAS mutations and is correlated with ALK expression. Molecular Cancer. 2009; 9: 188-190.
    • (2009) Molecular Cancer , vol.9 , pp. 188-190
    • Zhang, X.1    Zhang, S.2    Yang, X.3
  • 8
    • 80052793410 scopus 로고    scopus 로고
    • A Novel ALK Secondary Mutation and EGFR Signaling Cause Resistance to ALK Kinase Inhibitors
    • Takaaki Sasaki T, Koivunen J, Ogino A, et al. A Novel ALK Secondary Mutation and EGFR Signaling Cause Resistance to ALK Kinase Inhibitors. Cancer Research. 2011; 71: 6051-6060.
    • (2011) Cancer Research , vol.71 , pp. 6051-6060
    • Takaaki, S.T.1    Koivunen, J.2    Ogino, A.3
  • 9
    • 74249123333 scopus 로고    scopus 로고
    • ALK Gene Rearrangements A new therapeutic target in an molecularly defined subset of non-small cell lung cancer
    • Solomon B, Varella-Garcia M, Camidge D. ALK Gene Rearrangements A new therapeutic target in an molecularly defined subset of non-small cell lung cancer. Journal of Thoracic Oncology. 2009; 4: 1451.
    • (2009) Journal of Thoracic Oncology , vol.4 , pp. 1451
    • Solomon, B.1    Varella-Garcia, M.2    Camidge, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.