Fyn positively regulates the activation of DAP12 and Fcrγ-mediated costimulatory signals by RANKL during osteoclastogenesis

Cellular Signalling

Volumn 24, Issue 6, 2012, Pages 1306-1314

  Kim, H S ^a   Kim, D K ^a   Kim, A R ^a   Mun, S H ^a,b   Lee, S K ^b   Kim, J H ^a   Kim, Y M ^c   Choi, W S ^a  

^a Konkuk University   (South Korea)

^b UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

^c Duksung Women's University   (South Korea)

Author keywords

Costimulatory signal; DAP12; Differentiation; Fcr ; Fyn; Osteoclast

Indexed keywords

ADAPTOR PROTEIN; CATHEPSIN K; FC RECEPTOR; FC RECEPTOR GAMMA; KILLER CELL ACTIVATING RECEPTOR ASSOCIATED PROTEIN; OSTEOCLAST DIFFERENTIATION FACTOR; PROTEIN C FOS; PROTEIN GAB2; PROTEIN ITAM; PROTEIN KINASE FYN; PROTEIN KINASE SYK; PROTEIN NFATC1; PROTEIN PLCGAMMA; PROTEIN TYROSINE KINASE; RECEPTOR ACTIVATOR OF NUCLEAR FACTOR KAPPA B; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR NFAT; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BONE MARROW CELL; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; IMMUNOPRECIPITATION; MACROPHAGE; MOUSE; NONHUMAN; OSTEOCLASTOGENESIS; OSTEOLYSIS; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; BONE MARROW CELLS; CELL DIFFERENTIATION; CELLS, CULTURED; GENE DELETION; MACROPHAGES; MICE; MICE, INBRED C57BL; OSTEOCLASTS; PROTO-ONCOGENE PROTEINS C-FYN; RANK LIGAND; RECEPTORS, IGG; SIGNAL TRANSDUCTION;

EID: 84859033703     PISSN: 08986568     EISSN: 18733913     Source Type: Journal    
DOI: 10.1016/j.cellsig.2012.02.014     Document Type: Article

References (26)

1. Udagawa N., Takahashi N., Akatsu T., Tanaka H., Sasaki T., Nishihara T., Koga T., Martin T.J., Suda T. Proceedings of the National academy of Sciences of the United States of America 1990, 87:7260-7264.
2. Boyle W.J., Simonet W.S., Lacey D.L. Nature 2003, 423:337-342.
3. Lagasse E., Weissman I.L. Cell 1997, 89:1021-1031.
4. Kong Y.Y., Yoshida H., Sarosi I., Tan H.L., Timms E., Capparelli C., Morony S., Oliveira-dos-Santos A.J., Van G., Itie A., Khoo W., Wakeham A., Dunstan C.R., Lacey D.L., Mak T.W., Boyle W.J., Penninger J.M. Nature 2004, 397:315-323.
5. Gingery A., Bradley E., Shaw A., Oursler M.J. Journal of Cellular Biochemistry 2003, 89:165-179.
6. Walsh M.C., Kim N., Kadono Y., Rho J., Lee S.Y., Lorenzo J., Choi Y. Annual Review of Immunology 2006, 24:33-63.
7. Takayanagi H. Nature 2007, 7:292-304.
8. Soriano P., Montgomery C., Geske R., Bradley A. Cell 1991, 64:693-702.
9. Boyce B.F., Yoneda T., Lowe C., Soriano P., Mundy G.R. The Journal of Clinical Investigation 1992, 90:1622-1627.
10. Kim H.J., Zhang K., Zhang L., Ross F.P., Teitelbaum S.L., Faccio R. Proceedings of the National Academy of Sciences of the United States of America 2009, 106:2325-2330.
11. Shinohara M., Koga T., Okamoto K., Sakaguchi S., Arai K., Yasuda H., Takai T., Kodama T., Morio T., Geha R.S., Kitamura D., Kurosaki T., Ellmeier W., Takayanagi H. Cell 2008, 132:794-806.
12. Koga T., Inui M., Inoue K., Kim S., Suematsu A., Kobayashi E., Iwata T., Ohnishi H., Matozaki T., Kodama T., Taniguchi T., Takayanagi H., Takai T. Nature 2004, 428:758-763.
13. Takayanagi H. Nature Reviews. Rheumatology 2009, 5:667-676.
14. Ha H., Kwak H.B., Le S.W., Kim H.H., Lee Z.H. Experimental & Molecular Medicine 2003, 35:279-284.
15. Gohda J., Akiyama T., Koga T., Takayanagi H., Tanaka S., Inoue J. The EMBO Journal 2005, 24:790-799.
16. Mócsai A., Humphrey M.B., Van Ziffle J.A., Hu Y., Burghardt A., Spusta S.C., Majumdar S., Lanier L.L., Lowell C.A., Nakamura M.C. Proceedings of the National Academy of Sciences of the United States of America 2004, 101:6158-6163.
17. Zou W., Reeve J.L., Liu Y., Teitelbaum S.L., Ross F.P. Molecular Cell 2008, 31:422-431.
18. Lowell C.A., Soriano P. Genes & Development 1996, 10:1845-1857.
19. Takeuchi M., Kuramochi S., Fusaki N., Nada S., Kawamura-Tsuzuku J., Matsuda S., Semba K., Toyoshima K., Okada M., Yamamoto T. The Journal of Biological Chemistry 1993, 268:27413-27419.
20. Parravicini V., Gadina M., Kovarova M., Odom S., Gonzalez-Espinosa C., Furumoto Y., Saitoh S., Samelson L.E., O'Shea J.J., Rivera J. Nature Immunology 2002, 3:741-748.
21. Hong H., Kitaura J., Xiao W., Horejsi V., Ra C., Lowell C.A., Kawakami Y., Kawakami T. Blood 2007, 110:2511-2519.
22. Kim H.J., Warren J.T., Kim S.Y., Chappel J.C., DeSelm C.J., Ross F.P., Zou W., Teitelbaum S.L. Journal of Cellular Biochemistry 2010, 111:1107-1113.
23. Sengupta P., Baird B., Holowka D. Seminars in Cell & Developmental Biology 2007, 18:583-590.
24. Ha H., Kwak H.B., Le S.W., Kim H.H., Lee Z.H. Experimental and Molecular 2003, 35:279-284.
25. Wong B.R., Besser D., Kim N., Arron J.R., Vologodskaia M., Hanafusa H., Choi Y. Molecular Cell 1999, 4:1041-1049.
26. Taguchi Y., Gohda J., Koga T., Takayanagi H., Inoue J. Genes to Cells 2009, 14:1331-1345.