Fatigue in multiple sclerosis: A diagnostic and therapeutic challenge

Expert Opinion on Pharmacotherapy

Volumn 13, Issue 6, 2012, Pages 791-793

  Paul, Friedemann ^a   Veauthier, Christian ^b  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b Hanse Klinikum Stralsund   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CLINICAL FEATURE; DIFFERENTIAL DIAGNOSIS; DISEASE ASSOCIATION; DISEASE SEVERITY; EDITORIAL; FATIGUE; HUMAN; MULTIPLE SCLEROSIS; QUESTIONNAIRE; SYMPTOM;

FATIGUE; HUMANS; MULTIPLE SCLEROSIS;

EID: 84858853178     PISSN: 14656566     EISSN: 17447666     Source Type: Journal    
DOI: 10.1517/14656566.2012.667075     Document Type: Editorial

References (23)

1. Bakshi R. Fatigue associated with multiple sclerosis: Diagnosis, impact and management. Mult Scler 2003;9:219-27
2. Krupp LB, Alvarez LA, LaRocca NG, Scheinberg LC. Fatigue in multiple sclerosis. Arch Neurol 1988;45:435-7
3. Comi G, Leocani L, Rossi P, Colombo B. Physiopathology and treatment of fatigue in multiple sclerosis. J Neurol 2001;248:174-9
4. Multiple Sclerosis Council for Clinical Practice Guidelines. Fatigue and Multiple Sclerosis: Evidence-Based Management Strategies for Fatigue in Multiple Sclerosis. Paralyzed Veterans of America; Washington, DC: 1998
5. Tellez N, Rio J, Tintore M, et al. Does the Modified Fatigue Impact Scale offer a more comprehensive assessment of fatigue in MS? Mult Scler 2005;11:198-202
6. Krupp LB, Elkins LE. Fatigue and declines in cognitive functioning in multiple sclerosis. Neurology 2000;55:934-9
7. Flachenecker P, Kumpfel T, Kallmann B, et al. Fatigue in multiple sclerosis: A comparison of different rating scales and correlation to clinical parameters. Mult Scler 2002;8:523-6
8. Attarian HP, Brown KM, Duntley SP, et al. The relationship of sleep disturbances and fatigue in multiple sclerosis. Arch Neurol 2004;61:525-8
9. Veauthier C, Radbruch H, Gaede G, et al. Fatigue in multiple sclerosis is closely related to sleep disorders: A polysomnographic cross-sectional study. Mult Scler 2011;17:613-22
10. Penner IK, Bechtel N, Raselli C, et al. Fatigue in multiple sclerosis: Relation to depression, physical impairment, personality and action control. Mult Scler 2007;13:1161-7
11. Mills RJ, Young CA. The relationship between fatigue and other clinical features of multiple sclerosis. Mult Scler 2011;17:604-12
12. Weinges-Evers N, Brandt AU, Bock M, et al. Correlation of self-assessed fatigue and alertness in multiple sclerosis. Mult Scler 2010;16:1134-40
13. Krupp LB, LaRocca NG, Muir-Nash J, Steinberg AD. The fatigue severity scale. Application to patients with multiple sclerosis and systemic lupus erythematosus. Arch Neurol 1989;46:1121-3
14. Pellicano C, Gallo A, Li X, et al. Relationship of cortical atrophy to fatigue in patients with multiple sclerosis. Arch Neurol 2010;67: 447-53
15. Mowry EM, Beheshtian A, Waubant E, et al. Quality of life in multiple sclerosis is associated with lesion burden and brain volume measurements. Neurology 2009;72:1760-5
16. Gottschalk M, Kumpfel T, Flachenecker P, et al. Fatigue and regulation of the hypothalamo-pituitary-adrenal axis in multiple sclerosis. Arch Neurol 2005;62:277-80
17. Flachenecker P, Rufer A, Bihler I, et al. Fatigue in MS is related to sympathetic vasomotor dysfunction. Neurology 2003;61:851-3
18. Hohn O, Strohschein K, Brandt AU, et al. No evidence for XMRV in German CFS and MS patients with fatigue despite the ability of the virus to infect human blood cells in vitro. PLoS One 2010;5(12):e15632
19. Melamud L, Golan D, Luboshitzky R, et al. Melatonin dysregulation, sleep disturbances and fatigue in multiple sclerosis. J Neurol Sci 2011; Epub ahead of print
20. Amato MP, Portaccio E. Management options in multiple sclerosis-associated fatigue. Expert Opin Pharmacother 2012;13:207-16
21. Grossman P, Kappos L, Gensicke H, et al. MS quality of life, depression and fatigue improve after mindfulness training: A randomized trial. Neurology 2010;75:1141-9
22. Andreasen A, Stenager E, Dalgas U. The effect of exercise therapy on fatigue and multiple sclerosis. Mult Scler 2011;17:1041-54
23. Petajan JH, Gappmeier E, White AT, et al. Impact of aerobic training on fitness and quality of life in multiple sclerosis. Ann Neurol 1996;39:432-41