Gastrointestinal involvement in spinal cord injury: A clinical perspective

Journal of Gastrointestinal and Liver Diseases

Volumn 21, Issue 1, 2012, Pages 75-82

  Ebert, Ellen ^a  

^a ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

Author keywords

Acute abdomen; Constipation; Fecal impaction; Neurogenic bowel

Indexed keywords

4 AMINOPYRIDINE; CISAPRIDE; ENEMA; GLYCOPYRRONIUM BROMIDE; NEOMYCIN; NEOSTIGMINE; PRUCALOPRIDE;

ABDOMINAL PAIN; ACALCULOUS CHOLECYSTITIS; ACUTE ABDOMEN; ANOREXIA; ARTICLE; AUTONOMIC HYPERREFLEXIA; CLINICAL FEATURE; CONSTIPATION; DECUBITUS; DIARRHEA; DISEASE ASSOCIATION; DYSPHAGIA; FECES IMPACTION; FECES INCONTINENCE; FEVER; FLATULENCE; GALLSTONE; GASTROINTESTINAL DISEASE; HEADACHE; HEMORRHOID; HEMORRHOIDECTOMY; HUMAN; INTESTINAL DYSMOTILITY; INTESTINE DISTENSION; INTESTINE FUNCTION; INTESTINE SOUND; LEUKOCYTOSIS; MORTALITY; NAUSEA; NEUROGENIC BOWEL; PATHOPHYSIOLOGY; RECTUM HEMORRHAGE; RESTLESSNESS; RHIZOTOMY; SPINAL CORD INJURY; UNSPECIFIED SIDE EFFECT; VOMITING;

ESOPHAGEAL DISEASES; GALLBLADDER DISEASES; GASTROINTESTINAL DISEASES; HUMANS; INTESTINAL DISEASES; SPINAL CORD INJURIES; STOMACH DISEASES;

EID: 84858806983     PISSN: 18418724     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (100)

1. Spinal cord injury: facts and figures at a glance. J Spinal Cord Med 2000;23:51-53.
2. Wyndaele M, Wyndaele JJ. Incidence, prevalence and epidemiology of spinal cord injury: what learns a worldwide literature survey? Spinal Cord 2006;44:523-529.
3. Stone JM, Nino-Murcia M, Wolfe VA, Perkash I. Chronic gastrointestinal problems in spinal cord injury patients: a prospective analysis. Am J Gastroenterology 1990;85:1114-1119.
4. Han TR, Kim JH, Kwon BS. Chronic gastrointestinal problems and bowel dysfunction in patients with spinal cord injury. Spinal Cord 1998;36:485-490.
5. Liu CW, Huang CC, Chen CH, Yang YH, Chen TW, Huang MH. Prediction of severe neurogenic bowel dysfunction in persons with spinal cord injury. Spinal Cord 2010;48:554-559.
6. Harari D, Sarkarati M, Gurwitz JH, McGlinchey-Berroth G, Minaker KL. Constipation-related symptoms and bowel program concerning individuals with spinal cord injury. Spinal Cord 1997;35:394-401.
7. Menter R, Weitzenkamp D, Cooper D, Bingley J, Charlifue S, Whiteneck G. Bowel management outcomes in individuals with long-term spinal cord injuries. Spinal Cord 1997;35:608-612.
8. DeLooze D, van Laere M, DeMuynck M, Beke R, Elewaut A. Constipation and other chronic gastrointestinal problems in spinal cord injury patients. Spinal Cord 1998;36:63-66.
9. Lynch AC, Wong C, Anthony A, Dobbs BR, Frizelle FA. Bowel dysfunction following spinal cord injury: a description of bowel function in a spinal cord-injured population and comparison with age and gender matched controls. Spinal Cord 2000;38:717-723.
10. Krogh K, Nielsen J, Djurhuus JC, Mosdal C, Sabroe S, Laurberg S. Colorectal function in patients with spinal cord lesions. Dis Colon Rectum 1997;40:1233-1239.
11. Chen C Y, Chuang TY, Tsai YA, et al. Loss of sympathetic coordination appears to delay gastrointestinal transit in patients with spinal cord injury. Dig Dis Sci 2004;49:738-743.
12. Ng C, Prott G, Rutkowski S, et al. Gastrointestinal symptoms in spinal cord injury: relationships with level of injury and psychologic factors. Dis Colon Rect 2005;48:1562-1568.
13. Gore RM, Mintzer RA, Calenoff L. Gastrointestinal complications of spinal cord injury. Spine 1981; 6:538-544.
14. Matsumura JS, Prystowsky JB, Bresticker MA, Meyer PR, Joehl RJ, Nahrwold DL. Gastrointestinal tract complications after acute spine injury. Arch Surg 1996;130:751-753.
15. Juler GL, Eltorai IM. The acute abdomen in spinal cord injury patients. Paraplegia 1985;23:118-123.
16. Berlly MH, Wilmot CB. Acute abdominal emergencies during the frst four weeks after spinal cord injury. Arch Phys Med Rehabil 1984;65:687-690.
17. Kewalramani LS. Neurogenic gastroduodenal ulceration and bleeding associated with spinal cord injuries. J Trauma 1979;19:259-265.
18. Bowen JC, Fleming WH, Thompson JC. Increased gastrin release following penetrating central nervous system injury. Surgery 1974;75:720-724.
19. Sutton RA, Macphail I, Bentley R, Nandy MK. Acute gastric dilatation as a relatively late complication of tetraplegia due to very high cervical cord injury. Paraplegia 1981;19:17-19.
20. Longo WE, Ballantyne GH, Modlin IM. The colon, anorectum, and spinal cord patient. A review of the functional alterations of the denervated hindgut. Dis Colon Rectum 1989;32:261-267.
21. Cosman BC, Vu TT. Lidocaine anal block limits autonomic dysrefexia during anorectal procedures in spinal cord injury: a randomized, double-blind, placebo-controlled trial. Dis Colon Rectum 2005;48:1556-1561.
22. Miller BJ, Geraghty TJ, Wong CH, Hall DF, Cohen JR. Outcome of the acute abdomen in patients with previous spinal cord injury.ANZ J Surg 2001;71:407-411.
23. Bar-On Z, Ohry A. The acute abdomen in spinal cord injury individuals. Paraplegia 1995;33:704-706.
24. Neumayer LA, Bull DA, Mohr JD, Putham CW. The acutely affected abdomen in paraplegic spinal cord injury patients. Ann Surg 1990;212:561-566.
25. Sugarman B, Brown D, Musher D. Fever and infection in spinal cord injury patients. JAMA 1982;248:66-70.
26. Strauther GR, Longo WE, Virgo KS, Johnson FE. Appendicitis in patients with previous spinal cord injury. Am J Surg 1999;178:403-405.
27. Nino-Murcia M, Friedland GW. Functional abnormalities of the gastrointestinal tract in patients with spinal cord injuries: evaluation with imaging procedures.AJR Am J Roentgenol 1992;158:279-281.
28. Valles M, Mearin F. Pathophysiology of bowel dysfunction in patients with motor incomplete spinal cord injury: comparison with patients with motor complete spinal cord injury. Dis Colon Rectum 2009;52:1589-1597.
29. MacDonagh R, Sun WM, Thomas DG, Smallwood R, Read NW. Anorectal function in patients with complete supraconal spinal cord lesions. Gut 1992;33:1532-1538.
30. Shafik A. Electrorectogram study of the neuropathic rectum. Paraplegia 1995;33:346-349.
31. Yim SY, Yoon SH, Lee IY, Rah EW, Moon HW. A comparison of bowel care patterns in patients with spinal cord injury: upper motor neuron bowel vs lower motor neuron bowel. Spinal Cord 2001;39:204-207.
32. Walter SA, Morren GL, Ryn AK, Hallbook O. Rectal pressure response to a meal in patients with high spinal cord injury. Arch Phys Med Rehabil 2003;84:108-111.
33. Greving I, Tegenthoff M, Nediat S, et al. Anorectal functions in patients with spinal cord injury. Neurogastroenterol Motil 1998;10:509-515.
34. Beuret-Blanquart F, Weber J, Gouverneur JP, Demangeon S, Denis P. Colonic transit time and anorectal manometric anomalies in 19 patients with complete transaction of the spinal cord. J Auton Nerv Syst 1990;30:199-207.
35. Krogh K, Mosdal C, Gregersen H, Laurberg S. Rectal wall properties in patients with acute and chronic spinal cord lesions. Dis Colon Rectum 2002;45:641-649.
36. Haas U, Geng V. Sensation of defecation in patients with spinal cord injury. Spinal Cord 2008;46:107-112.
37. Fajardo NR, Pasiliao RV, Modeste-Duncan R, Creasey G, Bauman WA, Korsten MA. Decreased colonic motility in persons with chronic spinal cord injury. Am J Gastroenterol 2003;98:128-134.
38. Aaronson MJ, Freed MM, Burakoff R. Colonic myoelectric activity in persons with spinal cord injury. Dig Dis Sci 1985;30:295-300.
39. Keshavarzian A, Barnes WE, Bruninga K, Nemchausky B, Mermall H, Bushnell D. Delayed colonic transit in spinal cord-injured patients measured by indium-111 Amberlite scintigraphy. Am J Gastroenterol 1995;90:1295-1300.
40. De Looze DA, De Muynck MC, Van Laere M, De Vos MM, Elewaut AG. Pelvic foor function in patients with clinically complete spinal cord injury and its relation to constipation. Dis Colon Rectum 1998;41:778-786.
41. Media S, Christensen P, Lauge I, Al-Hashimi M, Laurberg S, Krogh K. Reproducibility and validity of radiographically determined gastrointestinal and segmental colonic transit times in spinal cord-injured patients. Spinal Cord 2009; 47:72-75.
42. Kirshblum S, Johnston MV, Brown J, O'Connor KC, Jarosz P. Predictors of dysphagia after spinal cord injury. Arch Phys Med Rehabil 1999;80:1101-1105.
43. Singh G, Triadaflopoulos G. Gastroesophageal refux disease in patients with spinal cord injury. J Spinal Cord Med 2000 23:23-27.
44. Neville AL, Crookes P, Velmahos GC, Vlahos A, Theodorou D, Lucas CE. Esophageal dysfunction in cervical spinal cord injury: a potentially important mechanism of aspiration. J Trauma 2005;59:905-911.
45. Segal JL, Milne N, Brunnemann SR, Lyons KP. Metoclopramide-induced normalization of impaired gastric emptying in spinal cord injury. Am J Gastroenterol 1987;82:1143-1148.
46. Kao CH, Ho YJ, Changlai SP, Ding HJ. Gastric emptying in spinal cord injury patients. Dig Dis Sci 1999;44:1512-1515.
47. Zhang RL, Chayes Z, Korsten MA, Bauman WA. Gastric emptying rates to liquid or solid meals appear to be unaffected by spinal cord injury. Am J Gastroenterol 1994;89:1856-1858.
48. Lin VW, Kim KH, Hsiao I, Brown W. Functional magnetic stimulation facilitates gastric emptying. Arch Phys Med Rehabil 2002;83:806-810.
49. Roth EJ, Fenton LL, Gaebler-Spira DJ, Frost FS, Yarkony GM. Superior mesenteric artery syndrome in acute traumatic quadriplegia: case reports and literature review. Arch Phys Med Rehabil 1991;72:417-420.
50. Harari D, Minaker KL. Megacolon in patients with chronic spinal cord injury. Spinal Cord 2000;38: 331-339.
51. Faaborg PM, Christensen P, Rosenkilde M, Laurberg S, Krogh K. Do gastrointestinal transit times and colonic dimensions change with time since spinal cord injury? Spinal Cord 2011;49:549-553.
52. Fenton-Lee D, Yeo BW, Jones RF, Engel S. Colonic volvulus in the spinal cord injured patient. Paraplegia 1993;31:393-397.
53. Connell AM, Frankel H, Guttmann L. The motility of the pelvic colon following complete lesions of the spinal cord. Paraplegia 1963;1:98-115.
54. Scott D, Papa MZ, Sareli M, Velano A, Ben-Ari G Y, Koller M. Management of hemorrhoidal disease in patients with chronic spinal cord injury. Tech Coloproctol 2002;6:19-22.
55. Stratton MD, McKirgan LW, Wade TP, et al. Colorectal cancer in patients with previous spinal cord injury. Dis Colon Rectum 1996;39:965-968.
56. Cameron KJ, Nyulasi IB, Collier GR, Brown DJ. Assessment of the effect of increased dietary fbre intake on bowel function in patients with spinal cord injury. Spinal Cord 1996;34:277-283.
57. Badiali D, Bracci F, Castellano V, et al. Sequential treatment of chronic constipation in paraplegic subjects. Spinal Cord 1997;35:116-120.
58. House JG, Stiens SA. Pharmacologically initiated defecation for persons with spinal cord injury: effectiveness of three agents. Arch Phys Med Rehabil 1997;78:1062-1065.
59. Korsten MA, Singal AK, Monga A, et al. Anorectal stimulation causes increased colonic motor activity in subjects with spinal cord injury. J Spinal Cord Med 2007;30:31-35.
60. Lynch AC, Anthony A, Dobbs BR, Frizelle FA. Anorectal physiology following spinal cord injury. Spinal Cord 2000;38:573-580.
61. Ayas S, Leblebici B, Sozay S, Bayramoglu M, Niron EA. The effect of abdominal massage on bowel function in patients with spinal cord injury. Am J Phys Med Rehabil 2006;85:951-955.
62. Coggrave MJ, Norton C. The need for manual evacuation and oral laxatives in the management of neurogenic bowel dysfunction after spinal cord injury: a randomized controlled trial of a stepwise protocol. Spinal Cord 2010;48:504-510.
63. Liptak GS, Revell GM. Management of bowel dysfunction in children with spinal cord disease or injury by means of the enema continence catheter. J Pediatr 1992;120:190-194.
64. Christensen P, Bazzocchi G, Coggrave M, et al. A randomized, controlled trial of transanal irrigation versus conservative bowel management in spinal cord-injured patients. Gastroenterology 2006;131:738-747.
65. Krogh K, Christensen P, Sabroe S, Laurberg S. Neurogenic bowel dysfunction score. Spinal Cord 2006;44:625-631.
66. Faaborg PM, Christensen P, Kvitsau B, Buntzen S, Laurberg S, Krogh K. Long-term outcome and safety of transanal colonic irrigation for neurogenic bowel dysfunction. Spinal Cord 2009;47:545-549.
67. Teichman JM, Zabihi N, Kraus SR, Harris JM, Barber DB. Long-term results for malone antegrade continence enema for adults with neurogenic bowel disease. Urology 2003;61:502-506.
68. Worsoe J, Christensen P, Krogh K, Buntzen S, Laurberg S. Long-term results of antegrade colonic enema in adult patients: assessment of functional results. Dis Colon Rectum 2008;51:1523-1528.
69. Badali D, Corazziari E, Habib FI, Bausano G, Viscardi A, Anzini F, et al. A double-blind controlled trial on the effect of cisapride in the treatment of constipation in paraplegic patients. Neurogastroenterol Motil 1991;3:263-267.
70. de Both PSM, de Groot GH, Slootman HR. Effects of cisapride on constipation in paraplegic patients: a placebo-controlled randomized double-blind cross-over study. Eur J Gastroenterol Hepatol 1992;4:1013-1017.
71. Krogh K, Jensen MB, Gandrup P, et al. Effcacy and tolerability of prucalopride in patients with constipation due to spinal cord injury. Scand J Gastroenterol 2002;37:431-436.
72. Korsten MA, Rosman AS, Ng A, et al. Infusion of neostigmine-glycopyrrolate for bowel evacuation in persons with spinal cord injury. Am J Gastroenterol 2005;100:1560-1565.
73. Rosman AS, Chaparala G, Monga A, Spungen AM, Bauman WA, Korsten MA. Intramuscular neostigmine and glycopyrrolate safely accelerated bowel evacuation in patients with spinal cord injury and defecatory disorders. Dig Dis Sci 2008;53:2710-2713.
74. ClinicalTrials.gov. Intranasal administration of neostigmine and glycopyrrolate for bowel evacuation. http://clinicaltrials.gov/ct2/show/NCT00855283
75. Cardenas DD, Ditunno J, Graziani V, et al. Phase 2 trial of sustained-release fampridine in chronic spinal cord injury. Spinal Cord 2007;45:158-168.
76. Krogh K, Christensen P. Neurogenic colorectal and pelvic floor dysfunction. Best PractRes Clin Gastroenterol 2009;23:531-543.
77. Gstaltner K, Rosen H, Hufgard J, Mark R, Schrei K. Sacral nerve stimulation as an option for the treatment of faecal incontinence in patients suffering from cauda equine syndrome. Spinal Cord 2008;46:644-647.
78. Binnie NR, Smith AN, Creasey GH, Edmond P. Constipation associated with chronic spinal cord injury: The effect of pelvic parasympathetic stimulation by the Brindley stimulator. Paraplegia 1991;29:463-469.
79. Valles M, Rodriguez A, Borau A, Mearin F. Effect of sacral anterior root stimulator on bowel dysfunction in patients with spinal cord injury. Dis Colon Rectum 2009;52:986-992.
80. Holzer B, Rosen HR, Novi G, Ausch C, Holbling N, Schiessel R. Sacral nerve stimulation for neurogenic faecal incontinence. Br J Surg 2007;94:749-753.
81. Chia YW, Lee TK, Kour NW, Tung KH, Tan ES. Microchip implants on the anterior sacral roots in patients with spinal trauma: does it improve bowel function? Dis Colon Rectum 1996;39:690-694.
82. Lombardi G, Del Popolo G, Cecconi F, Surrenti E, Macchiarella A. Clinical outcome of sacral neuromodulation in incomplete spinal cord-injured patients suffering from neurogenic bowel dysfunctions. Spinal Cord 2010;48:154-159.
83. Egon G, Barat M, Colombel P, Visentin C, Isambert JL, Guerin J. Implantation of anterior sacral root stimulators combined with posterior sacral rhizotomy in spinal injury patients. World J Urol 1998;16:342-349.
84. Morren GL, Walter S, Hallbook O, Sjodahl R. Effects of magnetic sacral root stimulation on anorectal pressure and volume. Dis Colon Rectum 2001;44:1827-1833.
85. Tsai PY, Wang CP, Chiu FY, Tsai YA, Chang YC, Chuang TY. Efficacy of functional magnetic stimulation in neurogenic bowel dysfunction after spinal cord injury. J Rehabil Med 2009;41:41-47.
86. Branagan G, Tromans A, Finnis D. Effect of stoma formation on bowel care and quality of life in patients with spinal cord injury. Spinal Cord 2003;41:680-683.
87. Safadi BY, Rosito O, Nino-Murcia M, Wolfe VA, Perkash I. Which stoma works better for colonic dysmotility in the spinal cord injured patient? Am J Surg 2003;186:437-442.
88. Kelly SR, Shashidharan M, Borwell B, Tromans AM, Finnis D, Grundy DJ. The role of intestinal stoma in patients with spinal cord injury. Spinal Cord 1999;37:211-214.
89. Rosito O, Nino-Murcia M, Wolfe VA, Kiratti BJ, Perkash I. The effects of colostomy on the quality of life in patients with spinal cord injury: a retrospective analysis. J Spinal Cord Med 2002;25:174-183.
90. Moonka R, Stiens SA, Resnick WJ, et al. The prevalence and natural history of gallstones in spinal cord injured patients. J Am Coll Surg 1999;189:274-281.
91. Ketover SR, Ansel HJ, Goldish G, Roche B, Gebhard RL. Gallstones in chronic spinal cord injury: is impaired gallbladder emptying a risk factor? Arch Phys Med Rehabil 1996;77:1136-1138.
92. Park TH, Byun JH, Suh JH, et al. A study on the incidence of gallstones in patients with spinal cord injury. Korean J Gastroenterol 1998;31:227-232.
93. Xia CS, Han YQ, Yang X Y, Hong GX. Spinal cord injury and cholelithiasis. Hepatobiliary Pancreat Dis Int 2004;3:595-598.
94. Rotter KP, Larrain CG. Gallstones in spinal cord injury (SCI): a late medical complication? Spinal Cord 2003;41: 105-108.
95. Tandon RK, Jain RK, Garg PK. Increased incidence of biliary sludge and normal gallbladder contractility in patients with high spinal cord injury. Gut 1997;41:682-687.
96. Fealey RD, Szurszewski JH, Merritt JL, DiMagno EP. Effect of traumatic spinal cord transaction on human upper gastrointestinal motility and gastric emptying. Gastroenterology 1984;87: 69-75.
97. Apstein MD, Dalecki-Chipperfeld K. Spinal cord injury is a risk factor for gallstone disease Gastroenterology 1987;92:966-968.
98. Moonka R, Stiens SA, Stelzner M. Atypical gastrointestinal symptoms are not associated with gallstones in patients with spinal cord injury. Arch Phys Med Rehabil 2000;81: 1085-1089.
99. Ahmed HU, Smith JB, Rudderow DJ, Longo WE, Virgo KS, Johnson FE. Cholecystectomy in patients with previous spinal cord injury. Am J Surg 2002;184: 452-459.
100. Romero Ganuza FJ, La Banda G, Montalvo R, Mazaira J. Acute acalculous cholecystitis in patients with acute traumatic spinal cord injury. Spinal Cord 1997;35: 124-128.