Intramuscular neostigmine and glycopyrrolate safely accelerated bowel evacuation in patients with spinal cord injury and defecatory disorders

Digestive Diseases and Sciences

Volumn 53, Issue 10, 2008, Pages 2710-2713

  Rosman, Alan S ^a,b   Chaparala, Geeta ^a,b   Monga, Amit ^a,b   Spungen, Ann M ^a,b   Bauman, William A ^a,b   Korsten, Mark A ^a  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

Bowel care; Difficulty with evacuation; Glycopyrrolate; Neostigmine; Spinal cord injury

Indexed keywords

GLYCOPYRRONIUM BROMIDE; NEOSTIGMINE; PLACEBO;

ABDOMINAL CRAMP; ADULT; ARTICLE; CLINICAL ARTICLE; CLINICAL EVALUATION; CLINICAL TRIAL; CONTROLLED STUDY; DEFECATION; DEFECATION DISORDER; DEMOGRAPHY; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; FEMALE; HUMAN; MALE; PRIORITY JOURNAL; SALIVATION; SIDE EFFECT; SPINAL CORD INJURY; TREATMENT OUTCOME; XEROSTOMIA;

ADULT; BLOOD PRESSURE; CONSTIPATION; CROSS-OVER STUDIES; DEFECATION; DOUBLE-BLIND METHOD; GLYCOPYRROLATE; HEART RATE; HUMANS; INJECTIONS, INTRAMUSCULAR; MIDDLE AGED; MUSCARINIC ANTAGONISTS; NEOSTIGMINE; PARASYMPATHOMIMETICS; SPINAL CORD INJURIES;

EID: 50949104720     PISSN: 01632116     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10620-008-0216-z     Document Type: Article

References (19)

1. JM Stone M Nino Murcia VA Wolfe I Perkash 1990 Chronic gastrointestinal problems in spinal cord injury patients: a prospective analysis Am J Gastroenterol 85 1114 1119
2. AK Singal AS Rosman WA Bauman MA Korsten 2006 Recent concepts in the management of bowel problems after spinal cord injury Adv Med Sci 51 15 22
3. Stiens SA, Fajardo NR, Korsten MA (2003) The gastrointestinal system after spinal cord injury. In: Lin V (ed) Spinal cord medicine. Demos Medical Publishing, New York, pp 321-348
4. RJ Ponec MD Saunders MB Kimmey 1999 Neostigmine for the treatment of acute colonic pseudo-obstruction N Engl J Med 341 137 141
5. GM Eisen TH Baron JA Dominitz DO Faigel JL Goldstein JF Johanson JS Mallery HM Raddawi JJ Vargo JP Waring RD Fanelli J Wheeler Harbaugh 2002 Acute colonic pseudo-obstruction Gastrointest Endosc 56 789 792
6. RM Penner MJ Jacka PG Brindley 2005 Best evidence in critical care medicine: medical therapy of acute colonic pseudo-obstruction: a moving experience Can J Anaesth 52 542 543
7. MD Saunders MB Kimmey 2005 Systematic review: acute colonic pseudo-obstruction Aliment Pharmacol Ther 22 917 925
8. MA Korsten AS Rosman A Ng E Cavusoglu AM Spungen M Radulovic J Wecht WA Bauman 2005 Infusion of neostigmine-glycopyrrolate for bowel evacuation in persons with spinal cord injury Am J Gastroenterol 100 1560 1565
9. Package insert for neostigmine methylsulfate (2005) Sicor Pharmaceuticals, Irvine, CA
10. SA Stiens W Luttrel JE Binard 1998 Polyethylene glycol versus vegetable oil based bisacodyl suppositories to initiate side-lying bowel care: a clinical trial in persons with spinal cord injury Spinal Cord 36 777 781
11. Taylor P (2006) Anticholinesterase agents. In: Brunton LL (ed) Goodman & Gilman's the pharmacological basis of therapeutics. McGraw-Hill, New York, pp 201-216
12. Taylor P (2006) Agents acting at the neuromuscular junction and autonomic ganglia. In: Brunton LL (ed) Goodman & Gilman's the pharmacological basis of therapeutics. McGraw-Hill, New York, p 227
13. Brown JH, Taylor P (2006) Muscarinic receptor agonists and antagonists. In: Brunton LL (ed) Goodman & Gilman's the pharmacological basis of therapeutics. McGraw-Hill, New York, p 197
14. JL Wilkins JD Hardcastle CV Mann L Kaufman 1970 Effects of neostigmine and atropine on motor activity of ileum, colon, and rectum of anaesthetized subjects Br Med J 1 793 794
15. CS Child 1984 Prevention of neostigmine-induced colonic activity Anaesthesia 39 1083 1085
16. M Broggini C Benvenuti V Botta A Fossati M Valenti 1991 Bioavailability of intranasal neostigmine: comparison with intravenous route Meth Find Exp Clin Pharmacol 13 193 198
17. A Sghirlanzoni D Pareyson C Benvenuti G Cei V Cosi M Lombardi M Nicora R Ricciardi F Cornelio 1992 Efficacy of intranasal administration of neostigmine in myasthenic patients J Neurol 239 165 169
18. A Di Costanzo A Toriello C Mannara C Benvenuti G Tedeschi 1993 Intranasal versus intravenous neostigmine in myasthenia gravis: assessment by computer analysis of saccadic eye movements Clin Neuropharmacol 16 511 517
19. R Ricciardi B Rossi M Nicora A Sghirlanzoni A Muratorio 1991 Acute treatment of myasthenia gravis with intranasal neostigmine: clinical and electromyographic evaluation J Neurol Neurosurg Psychiatry 54 1061 1062