Bilirubin attenuates bufadienolide-induced ventricular arrhythmias and cardiac dysfunction in guinea-pigs by reducing elevated intracellular Na + levels

Cardiovascular Toxicology

Volumn 12, Issue 1, 2012, Pages 83-89

  Ma, Hongyue ^a   Zhang, Junfeng ^a   Jiang, Jiejun ^a   Zhou, Jing ^a   Xu, Huiqin ^a   Zhan, Zhen ^a   Wu, Qinan ^a   Duan, Jinao ^a  

^a NANJING UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

Anticancer agents; Arrhythmias; Bilirubin; Bufadienolides; Cardiac dysfunction

Indexed keywords

BILIRUBIN; BUFADIENOLIDE; SODIUM ION;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARRHYTHMIA SCORE; ARTICLE; CANCER CELL CULTURE; CARDIOTOXICITY; CELL PROLIFERATION; COMBINATION CHEMOTHERAPY; CONTROLLED STUDY; DEATH; DIASTOLIC BLOOD PRESSURE; DRUG DOSE COMPARISON; DRUG EFFECT; ECHOCARDIOGRAPHY; EX VIVO STUDY; GUINEA PIG; HEART DISEASE; HEART PROTECTION; HEART VENTRICLE ARRHYTHMIA; HEART VENTRICLE EXTRASYSTOLE; HEART VENTRICLE FIBRILLATION; HEART VENTRICLE TACHYCARDIA; HUMAN; HUMAN CELL; IN VIVO STUDY; MALE; MONOTHERAPY; MUSCLE CELL; NERVE BLOCK; NONHUMAN; PRIORITY JOURNAL; SCORING SYSTEM; SYSTOLIC BLOOD PRESSURE;

AMPHIBIAN VENOMS; ANIMALS; ARRHYTHMIAS, CARDIAC; BILIRUBIN; BUFANOLIDES; BUFO BUFO; CARDIOTONIC AGENTS; ELECTROCARDIOGRAPHY; GUINEA PIGS; HEART VENTRICLES; INTRACELLULAR FLUID; MALE; SODIUM;

ANURA; CAVIA;

EID: 84858798279     PISSN: 15307905     EISSN: 15590259     Source Type: Journal    
DOI: 10.1007/s12012-011-9142-y     Document Type: Article

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