Antiplasmodial activity of steroidal chalcones: Evaluation of their effect on hemozoin synthesis and the new permeation pathway of Plasmodium falciparum-infected erythrocyte membrane

Chemical Biology and Drug Design

Volumn 79, Issue 4, 2012, Pages 610-615

  Sisodia, Brijesh S ^a   Negi, Arvind S ^a   Darokar, Mahendra P ^a   Dwivedi, Upendra N ^b   Khanuja, Suman P S ^a,c  

^a CSIR CENTRAL INSTITUTE OF MEDICINAL AND AROMATIC PLANTS   (India)

^b UNIVERSITY OF LUCKNOW   (India)

^c NutraHelix Biotech Pvt Ltd   (India)

Author keywords

Antiplasmodial; Chalcone; Hemozoin; New permeation pathway; Sorbitol induced hemolysis

Indexed keywords

AMPHOTERICIN B DEOXYCHOLATE; ARTEMISININ; BENZENE DERIVATIVE; CHALCONE DERIVATIVE; CHLOROQUINE; DOXORUBICIN; FUROSEMIDE; GALLIC ACID; HEMOZOIN; QUININE; SORBITOL;

ANIMAL CELL; ANTIMALARIAL ACTIVITY; ARTICLE; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; CYTOTOXICITY; ERYTHROCYTE MEMBRANE; GROWTH INHIBITION; HEMOLYSIS; HUMAN; HUMAN CELL; IN VITRO STUDY; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PARASITE DEVELOPMENT; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RING OPENING; SCHIZONT; SIGNAL TRANSDUCTION; STRUCTURE ACTIVITY RELATION; SUBSTITUTION REACTION; VERO CELL;

ANIMALS; ANTIMALARIALS; CELL SURVIVAL; CERCOPITHECUS AETHIOPS; CHALCONES; ERYTHROCYTE MEMBRANE; ESTRADIOL; HEMEPROTEINS; HOST-PARASITE INTERACTIONS; HUMANS; MALARIA, FALCIPARUM; PLASMODIUM FALCIPARUM; VERO CELLS;

PLASMODIUM FALCIPARUM;

EID: 84858792566     PISSN: 17470277     EISSN: 17470285     Source Type: Journal    
DOI: 10.1111/j.1747-0285.2012.01323.x     Document Type: Article

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