Integrated genomic characterization of the kallikrein gene locus in cancer

Anticancer Research

Volumn 32, Issue 3, 2012, Pages 957-963

  Girgis, Andrew H ^a   Bui, Anna ^a   White, Nicole M ^a,b   Yousef, George M ^a,b  

^a ST MICHAEL'S HOSPITAL   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

Copy number aberrations; Gene expression; Glioblastoma multiforme; Kallikrein related peptidase; KLK; Ovarian cancer; Prostate cancer; Sarcoma; Tumor markers

Indexed keywords

KALLIKREIN; KALLIKREIN 13; KALLIKREIN 5; MESSENGER RNA;

ARTICLE; CANCER PROGNOSIS; CANCER SURVIVAL; COMPUTER MODEL; CONTROLLED STUDY; DISEASE FREE SURVIVAL; FEMALE; FIBROSARCOMA; GASTROINTESTINAL STROMAL TUMOR; GENE DOSAGE; GENE LOCUS; GENE LOSS; GENE OVEREXPRESSION; GENOMICS; GLIOBLASTOMA; HUMAN; HUMAN CELL; LEIOMYOSARCOMA; LIPOSARCOMA; MALE; MYXOSARCOMA; NUCLEOTIDE SEQUENCE; OVARY CANCER; PRIORITY JOURNAL; PROSTATE CANCER; SEROUS OVARY CANCER; SOFT TISSUE SARCOMA; SYNOVIAL SARCOMA; TRANSCRIPTOMICS;

GENOMICS; HUMANS; KALLIKREINS; NEOPLASMS;

EID: 84858783743     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Yousef GM and Diamandis EP: The human kallikrein gene family: new biomarkers for ovarian cancer. Cancer Treat Res 149: 165-187, 2009.
2. Yousef GM and Diamandis EP: Expanded human tissue kallikrein family - a novel panel of cancer biomarkers. Tumour Biol 23: 185-192, 2002. (Pubitemid 44858310)
3. Borgono CA, Michael IP and Diamandis EP: Human tissue kallikreins: physiologic roles and applications in cancer. Mol Cancer Res 2: 257-280, 2004. (Pubitemid 39031076)
4. Petraki CD, Gregorakis AK, Vaslamatzis MM, Papanastasiou PA, Yousef GM, Levesque MA and Diamandis EP: Prognostic implications of the immunohistochemical expression of human kallikreins 5, 6, 10 and 11 in renal cell carcinoma. Tumour Biol 27: 1-7, 2006. (Pubitemid 41832698)
5. White NM, Bui A, Mejia-Guerrero S, Chao J, Soosaipillai A, Youssef Y, Mankaruos M, Honey RJ, Stewart R, Pace KT, Sugar L, Diamandis EP, Dore J and Yousef GM: Dysregulation of kallikrein-related peptidases in renal cell carcinoma: potential targets of miRNAs. Biol Chem 391: 411-423, 2010.
6. Yousef GM, Obiezu CV, Luo LY, Magklara A, Borgono CA, Kishi T, Memari N, Michael P, Sidiropoulos M, Kurlender L, Economopolou K, Kapadia C, Komatsu N, Petraki C, Elliott M, Scorilas A, Katsaros D, Levesque MA and Diamandis EP: Human tissue kallikreins: from gene structure to function and clinical applications. Adv Clin Chem 39: 11-79, 2005. (Pubitemid 43588716)
7. Arsanious A, Bjarnason GA and Yousef GM: From bench to bedside: current and future applications of molecular profiling in renal cell carcinoma. Mol Cancer 8: 20, 2009.
8. Diamandis M, White NM and Yousef GM: Personalized medicine: marking a new epoch in cancer patient management. Mol Cancer Res 8: 1175-1187, 2010.
9. Yousef GM, Borgono CA, Popalis C, Yacoub GM, Polymeris ME, Soosaipillai A and Diamandis EP: In silico analysis of kallikrein gene expression in pancreatic and colon cancers. Anticancer Res 24: 43-51, 2004. (Pubitemid 38279687)
10. Yousef GM, Borgono CA, White NM, Robb JD, Michael IP, Oikonomopoulou K, Khan S and Diamandis EP: In silico analysis of the human kallikrein gene 6. Tumour Biol 25: 282-289, 2004. (Pubitemid 40082332)
11. Yousef GM, Polymeris ME, Yacoub GM, Scorilas A, Soosaipillai A, Popalis C, Fracchioli S, Katsaros D and Diamandis EP: Parallel overexpression of seven kallikrein genes in ovarian cancer. Cancer Res 63: 2223-2227, 2003. (Pubitemid 36538630)
12. Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature 455: 1061-1068, 2008.
13. Integrated genomic analyses of ovarian carcinoma. Nature 474: 609-615, 2011.
14. Barretina J, Taylor BS, Banerji S, Ramos AH, Lagos-Quintana M, Decarolis PL, Shah K, Socci ND, Weir BA, Ho A, Chiang DY, Reva B, Mermel CH, Getz G, Antipin Y, Beroukhim R, Major JE, Hatton C, Nicoletti R, Hanna M, Sharpe T, Fennell TJ, Cibulskis K, Onofrio RC, Saito T, Shukla N, Lau C, Nelander S, Silver SJ, Sougnez C, Viale A, Winckler W, Maki RG, Garraway LA, Lash A, Greulich H, Root DE, Sellers WR, Schwartz GK, Antonescu CR, Lander ES, Varmus HE, Ladanyi M, Sander C, Meyerson M and Singer S: Subtype-specific genomic alterations define new targets for soft-tissue sarcoma therapy. Nat Genet 42: 715-721, 2010.
15. Taylor BS, Schultz N, Hieronymus H, Gopalan A, Xiao Y, Carver BS, Arora VK, Kaushik P, Cerami E, Reva B, Antipin Y, Mitsiades N, Landers T, Dolgalev I, Major JE, Wilson M, Socci ND, Lash AE, Heguy A, Eastham JA, Scher HI, Reuter VE, Scardino PT, Sander C, Sawyers CL and Gerald WL: Integrative genomic profiling of human prostate cancer. Cancer Cell 18: 11-22, 2010.
16. Verhaak RG, Hoadley KA, Purdom E, Wang V, Qi Y, Wilkerson MD, Miller CR, Ding L, Golub T, Mesirov JP, Alexe G, Lawrence M, O'Kelly M, Tamayo P, Weir BA, Gabriel S, Winckler W, Gupta S, Jakkula L, Feiler HS, Hodgson JG, James CD, Sarkaria JN, Brennan C, Kahn A, Spellman PT, Wilson RK, Speed TP, Gray JW, Meyerson M, Getz G, Perou CM and Hayes DN: Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1. Cancer Cell 77: 98-110, 2010.
17. Irizarry RA, Hobbs B, Collin F, Beazer-Barclay YD, Antonellis KJ, Scherf U and Speed TP: Exploration, normalization, and summaries of high density oligonucleotide array probe level data. Biostatistics 4: 249-264, 2003.
18. Mermel CH, Schumacher SE, Hill B, Meyerson ML, Beroukhim R and Getz G: GISTIC2.0 facilitates sensitive and confident localization of the targets of focal somatic copy-number alteration in human cancers. Genome Biol 12: R41, 2011.
19. Taylor BS, Barretina J, Socci ND, Decarolis P, Ladanyi M, Meyerson M, Singer S and Sander C: Functional copy-number alterations in cancer. PLoS One 3: e3179, 2008.
20. Gabril M, White NM, Moussa M, Chow TF, Metias SM, Fatoohi E and Yousef GM: Immunohistochemical analysis of kallikrein-related peptidases in the normal kidney and renal tumors: potential clinical implications. Biol Chem 391: 403-409, 2010.