Myxedema coma: A new look into an old crisis

Journal of Thyroid Research

Volumn 2011, Issue , 2011, Pages

  Mathew, Vivek ^a   Misgar, Raiz Ahmad ^a   Ghosh, Sujoy ^a   Mukhopadhyay, Pradip ^a   Roychowdhury, Pradip ^a   Pandit, Kaushik ^a   Mukhopadhyay, Satinath ^a   Chowdhury, Subhankar ^a  

^a INSTITUTE OF POST GRADUATE MEDICAL EDUCATION AND RESEARCH   (India)

Author keywords

[No Author keywords available]

Indexed keywords

FUROSEMIDE; HYDROCORTISONE; LIOTHYRONINE; SEDATIVE AGENT; SODIUM CHLORIDE; THYROID HORMONE; THYROXINE; VASOPRESSIN RECEPTOR ANTAGONIST;

ARTIFICIAL VENTILATION; BLOOD CLOTTING DISORDER; BLOOD VESSEL PERMEABILITY; BRADYCARDIA; CARDIOGENIC SHOCK; CELL LEVEL; CLINICAL EXAMINATION; CLINICAL FEATURE; COMA; DISEASE ACTIVITY; DISEASE ASSOCIATION; DISEASE EXACERBATION; DISEASE SEVERITY; DOSE RESPONSE; DRUG EFFICACY; EARLY INTERVENTION; FLUID THERAPY; GEOGRAPHIC DISTRIBUTION; HEART ARRHYTHMIA; HIGH RISK PATIENT; HORMONAL THERAPY; HORMONE RESISTANCE; HORMONE SUBSTITUTION; HUMAN; HYPONATREMIA; HYPOTENSION; HYPOTHERMIA; HYPOTHYROIDISM; INFECTION; INTENSIVE CARE; LOADING DRUG DOSE; LUNG WEDGE PRESSURE; MAINTENANCE DRUG DOSE; MAINTENANCE THERAPY; MEDICAL HISTORY; MORBIDITY; MORTALITY; MYXEDEMA COMA; OXYGEN CONSUMPTION; OXYGENATION; PATHOGENESIS; PATIENT IDENTIFICATION; PREDICTOR VARIABLE; PRIORITY JOURNAL; RESPIRATION DEPRESSION; REVIEW; RISK FACTOR; SCORING SYSTEM; SEPSIS; STEROID THERAPY; TREATMENT OUTCOME; TROPICS; VENOUS PRESSURE;

EID: 84858780689     PISSN: 20908067     EISSN: 20420072     Source Type: Journal    
DOI: 10.4061/2011/493462     Document Type: Review

References (48)

1. L. Wartofsky, "Myxoedema coma", Endocrinology Metabolism Clinics of North America, vol. 35, pp. 687-698, 2006.
2. I. Rodríguez, E. Fluiters, L. F. Pérez-Méndez, R. Luna, C. Páramo, and R. V. García-Mayor, "Factors associated with mortality of patients with myxoedema coma: prospective study in 11 cases treated in a single institution", Journal of Endocrinology, vol. 180, no. 2, pp. 347-350, 2004. (Pubitemid 38312616)
3. T. Yamamoto, J. Fukuyama, and A. Fujiyoshi, "Factors associated with mortality of myxedema coma: report of eight cases and literature survey", Thyroid, vol. 9, no. 12, pp. 1167-1174, 1999. (Pubitemid 30038924)
4. P. Dutta, A. Bhansali, S. Masoodi, S. Bhadada, N. Sharma, and R. Rajput, "Predictors of outcome in myxoedema coma: a study from a tertiary care centre", Critical Care, vol. 12, no. 1, p. R1, 2008.
5. W. Reinhardt and K. Mann, "Incidence, clinical picture, and treatment of hypothyroid coma: results of a survey", Medizinische Klinik, vol. 92, pp. 521-524, 1997.
6. Report of a Committee of the Clinical Society of London to Investigate the Subject of Myxedema, vol. 21, Transactions Clinical Society, London, UK, 1888.
7. C. R. Wall, "Myxedema coma: diagnosis and treatment", American Family Physician, vol. 62, no. 11, pp. 2485-2490, 2000.
8. J. T. Nicoloff and J. S. Lo Presti, "Myxedema coma: a form of decompensated hypothyroidism", Endocrinology and Metabolism Clinics of North America, vol. 22, no. 2, pp. 279-290, 1993. (Pubitemid 23187801)
9. J. C. Galofré and R. V. García-Mayor, "Densidad de incidencia del coma mixedematoso", Endocrinologia, vol. 44, pp. 103-104, 1997.
10. M. Chu and T. F. Seltzer, "Myxedema coma induced by ingestion of raw bok choy", New England Journal of Medicine, vol. 362, no. 20, pp. 1945-1946, 2010.
11. D. G. Gardner, "Endocrine emergencies", in Greenspan's Basic and Clinical Endocrinology, D. G. Gardner and D. Shoback, Eds., McGraw-Hill, New York, NY, USA, 8th edition, 2007.
12. P. W. Ladenson, P. D. Goldenheim, and E. C. Ridgway, "Prediction and reversal of blunted ventilatory responsiveness in patients with hypothyroidism", American Journal of Medicine, vol. 84, no. 5, pp. 877-883, 1988.
13. W. R. Wilson and G. N. Bedell, "The pulmonary abnormalities in myxedema", The Journal of Clinical Investigation, vol. 39, pp. 42-55, 1960.
14. R. A. Massumi and J. L. Winnacker, "Severe depression of the respiratory center in myxedema", The American Journal of Medicine, vol. 36, no. 6, pp. 876-882, 1964.
15. F. R. Derubertis Jr., M. F. Michelis, M. E. Bloom, D. H. Mintz, J. B. Field, and B. B. Davis, "Impaired water excretion in myxedema", The American Journal of Medicine, vol. 51, no. 1, pp. 41-53, 1971.
16. W. R. Skowsky and T. A. Kikuchi, "The role of vasopressin in the impaired water excretion of myxedema", American Journal of Medicine, vol. 64, no. 4, pp. 613-621, 1978. (Pubitemid 8322910)
17. Y. C. Chen, M. A. Cadnapaphornchai, J. Yang et al., "Nonosmotic release of vasopressin and renal aquaporins in impaired urinary dilution in hypothyroidism", American Journal of Physiology-Renal Physiology, vol. 289, no. 4, pp. F672-F678, 2005. (Pubitemid 41324187)
18. W. M. Weirsinga, "Hypothyroidism and myxedema coma", in Endocrinology Adult and Pediatric, J. L. Jameson and L. J. Legroot, Eds., Saunders, Philadelphia, Pa, USA, 6th edition, 2010.
19. R. Polikar, A. G. Burger, U. Scherrer, and P. Nicod, "The thyroid and the heart", Circulation, vol. 87, no. 5, pp. 1435-1441, 1993. (Pubitemid 23133085)
20. J. B. Schenck, A. A. Rizvi, and T. Lin, "Severe primary hypothyroidism manifesting with torsades de pointes", American Journal of the Medical Sciences, vol. 331, no. 3, pp. 154-156, 2006.
21. C. G. Roberts and P. W. Ladenson, "Hypothyroidism", Lancet, vol. 363, no. 9411, pp. 793-803, 2004. (Pubitemid 38315171)
22. Y. D. Tang, J. A. Kuzman, S. Said, B. E. Anderson, X. Wang, and A. M. Gerdes, "Low thyroid function leads to cardiac atrophy with chamber dilatation, impaired myocardial blood flow, loss of arterioles, and severe systolic dysfunction", Circulation, vol. 112, no. 20, pp. 3122-3130, 2005. (Pubitemid 43113443)
23. F. Galetta, F. Franzoni, P. Fallahi et al., "Changes in heart rate variability and QT dispersion in patients with overt hypothyroidism", European Journal of Endocrinology, vol. 158, pp. 85-90, 2008. (Pubitemid 351211044)
24. F. Galetta, F. Franzoni, P. Fallahi et al., "Heart rate variability and QT dispersion in patients with subclinical hypothyroidism", Biomedicine and Pharmacotherapy, vol. 60, no. 8, pp. 425-430, 2006. (Pubitemid 44428098)
25. L. A. Osborn, B. Skipper, I. Arellano, S. D. MacKerrow, and M. H. Crawford, "Results of resting and ambulatory electrocardiograms in patients with hypothyroidism and after return to euthyroid status", Heart Disease, vol. 1, no. 1, pp. 8-11, 1999.
26. K. C. Das, M. Mukherjee, T. K. Sarkar et al., "Erythropoiesis and erythropoietin in hypo-and hyperthyroidism", Journal of Clinical Endocrinology and Metabolism, vol. 40, no. 2, pp. 211-220, 1975.
27. J. D. Hines, C. H. Halsted, R. C. Griggs, and J. W. Harris, "Megaloblastic anemia secondary to folate deficiency associated with hypothyroidism", Annals of Internal Medicine, vol. 68, no. 4, pp. 792-805, 1968.
28. R. Carmel and C. A. Spencer, "Clinical and subclinical thyroid disorders associated with pernicious anemia", Archives of Internal Medicine, vol. 142, no. 8, pp. 1465-1469, 1982.
29. G. R. Tudhope and G. M. Wilson, "Deficiency of vitamin b12 in hypothyroidism", The Lancet, vol. 279, no. 7232, pp. 703-706, 1962.
30. H. C. Ford and J. M. Carter, "Haemostasis in hypothyroidism", Postgraduate Medical Journal, vol. 66, no. 774, pp. 280-284, 1990. (Pubitemid 20110233)
31. J. J. Michiels, W. Schroyens, Z. Berneman, and M. Van der Planken, "Acquired von Willebrand syndrome type 1 in hypothyroidism: reversal after treatment with thyroxine", Clinical and Applied Thrombosis/Hemostasis, vol. 7, no. 2, pp. 113-115, 2001. (Pubitemid 32242186)
32. I. C. Nitu-Whalley and C. A. Lee, "Acquired von Willebrand syndrome-report of 10 cases and review of the literature", Haemophilia, vol. 5, no. 5, pp. 318-326, 1999. (Pubitemid 29495708)
33. E. M. Erfurth, U. B. Ericsson, K. Egervallah, and S. R. Lethagen, "Effect of acute desmopressin and of long-term thyroxine replacement onhaemostasis in hypothyroidism", Clinical Endocrinology, vol. 42, pp. 373-378, 1995.
34. L. Wartofsky and K. D. Burman, "Alterations in thyroid function in patients with systemic illness: the euthyroid sick syndrome", Endocrine Reviews, vol. 3, no. 2, pp. 164-217, 1982.
35. M. J. Hooper, "Diminished T. S. H. secretion during acute non thyroidal illness in untreated primary hypothyroidism", Lancet, vol. 1, no. 7949, pp. 48-49, 1976.
36. L. Brain, E. H. Jellinek, and K. Ball, "Hashimoto's disease and encephalopathy", Lancet, vol. 2, no. 7462, pp. 512-514, 1966.
37. P. Pozo-Rosich, P. Villoslada, A. Canton, R. Simo, A. Rovira, and X. Montalban, "Reversible white matter alterations in encephalopathy associated with autoimmune thyroid disease", Journal of Neurology, vol. 249, no. 8, pp. 1063-1065, 2002. (Pubitemid 35002230)
38. A. Canton, O. De Fabregas, M. Tintore et al., "Encephalopathy associated to autoimmune thyroid disease: a more appropriate termfor an underestimated condition?" Journal of the Neurological Sciences, vol. 176, pp. 65-69, 2000. (Pubitemid 30365012)
39. R. Peschen-Rosin, M. Schabet, and J. Dichgans, "Manifestation of Hashimoto's encephalopathy years before onset of thyroid disease", European Neurology, vol. 41, no. 2, pp. 79-84, 1999. (Pubitemid 29089971)
40. T. Yamamoto, "Delayed respiratory failure during the treatment of myxedema coma", Endocrinologia Japonica, vol. 31, no. 6, pp. 769-775, 1984.
41. J. G. Verbalis, S. R. Goldsmith, A. Greenberg, R. W. Schrier, and R. H. Sterns, "Hyponatremia treatment guidelines 2007: expert panel recommendations", American Journal of Medicine, vol. 120, no. 11, pp. S1-S21, 2007. (Pubitemid 350027722)
42. V. G. Pereira, E. S. Haron, N. Lima Neto, and G. A. Medeiros Nets, "Management of myxedema coma: report on three successfully treated cases with nasogastric or intravenous administration of triiodothyronine", Journal of Endocrinological Investigation, vol. 5, no. 5, pp. 331-334, 1982. (Pubitemid 13170676)
43. R. H. Sterns, J. D. Cappuccio, S. M. Silver, and E. P. Cohen, "Neurologic sequelae after treatment of severe hyponatremia: a multicenter perspective", Journal of the American Society of Nephrology, vol. 4, no. 8, pp. 1522-1530, 1994.
44. J. E. Brunner, J. M. Redmond, A. M. Haggar, D. F. Kruger, and S. B. Elias, "Central pontine myelinolysis and pontine lesions after rapid correction of hyponatremia: a prospective magnetic resonance imaging study", Annals of Neurology, vol. 27, no. 1, pp. 61-66, 1990. (Pubitemid 20031359)
45. D. N. Holvey, C. J. Goodner, J. T. Nicoloff, and J. T. Dowling, "Treatment of myxedema coma with intravenous thyroxine", Archives of Internal Medicine, vol. 113, pp. 89-96, 1964.
46. E. C. Ridgway, J. A. McCammon, J. Benotti, and F. Maloof, "Acute metabolic responses in myxedema to large doses of intravenous L-thyroxine", Annals of Internal Medicine, vol. 77, no. 4, pp. 549-555, 1972.
47. S. D. MacKerrow, L. A. Osborn, H. Levy, R. P. Eaton, and P. Economou, "Myxedema-associated cardiogenic shock treated with intravenous triiodothyronine", Annals of Internal Medicine, vol. 117, no. 12, pp. 1014-1015, 1992.
48. B. Hylander and U. Rosenqvist, "Treatment of myxoedema coma-factors associated with fatal outcome", Acta Endocrinologica, vol. 108, no. 1, pp. 65-71, 1985. (Pubitemid 15199352)