Heart rate variability and QT dispersion in patients with subclinical hypothyroidism

Biomedicine and Pharmacotherapy

Volumn 60, Issue 8, 2006, Pages 425-430

  Galetta, F ^a   Franzoni, F ^a   Fallahi, P ^a   Rossi, M ^a   Carpi, A ^a   Rubello, D ^b   Antonelli, A ^a   Santoro, G ^a  

^a UNIVERSITY OF PISA   (Italy)

^b S MARIA DELLA MISERICORDIA HOSPITAL   (Italy)

Author keywords

Cardiovascular autonomic function; Heart rate variability; QT dispersion; Subclinical hypothyroidism; Ventricular repolarization

Indexed keywords

LEVOTHYROXINE SODIUM; LIOTHYRONINE; THYROTROPIN; THYROXINE;

ADULT; AMBULATORY MONITORING; ANAMNESIS; ARTICLE; BODY SURFACE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; ELECTROCARDIOGRAM; FEMALE; HEART RATE VARIABILITY; HUMAN; HYPOTHYROIDISM; MALE; PATIENT SELECTION; PHYSICAL EXAMINATION; PRIORITY JOURNAL; QT INTERVAL; RANDOMIZATION; RANDOMIZED CONTROLLED TRIAL; THYROTROPIN BLOOD LEVEL; VOLUNTEER;

ELECTROCARDIOGRAPHY; FEMALE; HASHIMOTO DISEASE; HEART RATE; HUMANS; HYPOTHYROIDISM; MALE; MIDDLE AGED; THYROTROPIN; THYROXINE;

EID: 33748915307     PISSN: 07533322     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biopha.2006.07.009     Document Type: Article

References (20)

1. Althaus B.U., Staub J.J., Ryff-De Leche A., Oberhansli A., and Stahelin H.B. LDL/HDL-changes in subclinical hypothyroidism: possible risk factors for coronary heart disease. Clin. Endocrinol. (Oxf.) 28 (1988) 157-163
2. Monzani F., Caraccio N., Kozakowa M., Dardano A., Vittone F., Virdis A., et al. Effect of levothyroxine replacement on lipid profile and intima-media thickness in subclinical hypothyroidism: a double-blind, placebo- controlled study. J. Clin. Endocrinol. Metab. 89 (2004) 2099-2106
3. Hak A.E., Pols H.A., Visser T.J., Drexhage H.A., Hofman A., and Witteman J.C. Subclinical hypothyroidism is an independent risk factor for atherosclerosis and myocardial infarction in elderly women: the Rotterdam Study. Ann. Intern. Med. 132 (2000) 270-278
4. Zaidi M., Robert A., Fesler R., Derwael C., and Brohet C. Dispersion of ventricular repolarisation: a marker of ventricular arrhythmias in patients with previous myocardial infarction. Heart 78 (1997) 371-375
5. Task Force of European Society of Cardiology and The North American Society of Pacing and Electrophysiology. Heart rate variability. Standards of measurement, physiological interpretation, and clinical use. Eur. Heart J. 17 (1996) 354-381
6. Algra A., Tijssen J.G., Roelandt J.R., Pool J., and Lubsen J. Heart rate variability from 24-hour electrocardiography and the 2 year risk for sudden death. Circulation 88 (1993) 180-185
7. Tsuji H., Larson M.G., Venditti Jr. F.J., Manders E.S., Evans J.C., Feldman C.L., et al. Impact of reduced heart rate variability on risk for cardiac events: The Framingham Heart Study. Circulation 94 (1996) 2850-2855
8. Balanescu S., Galinier M., Fourcade J., Dorobantu M., Albenque J.P., Massabuau P., et al. Correlation between QT interval dispersion and ventricular arrhythmia in hypertension. Arch. Mal. Coeur Vaiss. 89 (1996) 987-990
9. Cacciatori V., Gemma M.L., Bellavere F., Castello R., De gregori M.E., Zoppini G., et al. Power spectral analysis of heart rate in hypothyroidism. Eur. J. Endocrinol. 143 (2000) 327-333
10. Altun A., Altun G., and Ozbay G. QT dispersion in Hypothyroidism. Int. J. Cardiol. 72 (1999) 93-95
11. Galetta F., Franzoni F., Cupisti A., Belliti D., Prattichizzo F., and Rolla M. QT interval dispersion in young women with anorexia nervosa. J. Pediatr. 140 (2002) 456-460
12. Beekman R.E., Hardeveld C., and Simonides W.S. Effect of thyroid state on systolic free calcium in resting and electrically stimulated cardiac myocytes. Acta Endocrinol. (Copenh.) 969 (1988) 18-27
13. Xing H.L., Zuo J.N., and Ma J.M. Changes in plasma concentration of atrial Matriuretic peptide and renine in patients with hypothyroidism. Chin. J. Endocrinol. Metab. 11 (1995) 68-70
14. Ori Z., Mouir G., Weiss J., Sayhouni X., and Singer H. Heart rate variability frequency domain. Cardiol. Clin. 10 (1992) 499-537
15. Nakagawa M., Takahashi N., Iwao T., Yonemochi H., Ooie T., Hara M., et al. Evaluation of autonomic influences on QT dispersion using the head-up tilt test in healthy subjects. PACE 22 (1999) 1158-1163
16. Manhem P., Bramnert M., and Hallengren B. Increased arterial and venous plasma noradrenaline levels in patients with primary hypothyroidism during hypothyroid as compared with euthyroid state. J. Endocrinol. Invest. 15 (1992) 763-765
17. Inukai T., Kobayashi I., Kobayashi T., Ishii A., Yamaguchi T., Yamaguchi Y., et al. Parasympathetic nervous system activity in hypothyroidism determined by R-R interval variations on electrocardiogram. J. Intern. Med. 228 (1990) 431-434
18. Polikar R., Kennedy B., Ziegler M., O'Connor D.T., Smith J., and Nicod P. Plasma norepinephrine kinetics, dopamine-betahydroxylase, and chromogranin-A in hypothyroid patients before and following replacement therapy. J. Clin. Endocrinol. Metab. 70 (1990) 277-281
19. Vagn Nielsen H., Hasselstrom K., Feldt-Rasmussen U., Mehlsen J., Siersbaek-Nielsen K., Friis T., et al. Increased sympathetic tone in forearm subcutaneous tissue in primary hypothyroidism. Clin. Physiol. 7 (1987) 297-302
20. Bing R.F., Brigss R.S.J., Burden A.C., Russell A.C., Swaks J.D., and Thurston H. Reversible hypertension and hypothyroidism. Clin. Endocrinol. (Oxf.) 13 (1980) 339-342