Effects of antenatal glucocorticoid therapy on hippocampal histology of preterm infants

PLoS ONE

Volumn 7, Issue 3, 2012, Pages

  Tijsseling, Deodata ^a   Wijnberger, Lia D E ^b   Derks, Jan B ^a   van Velthoven, Cindy T J ^a   de Vries, Willem B ^a   van Bel, Frank ^a   Nikkels, Peter G J ^a   Visser, Gerard H A ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b RIJNSTATE HOSPITAL   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

EOSIN; FUCHSINE; GLIAL FIBRILLARY ACIDIC PROTEIN; GLUCOCORTICOID; HEMATOXYLIN; KI 67 ANTIGEN; THIONINE; VIMENTIN; NEUROFILAMENT PROTEIN;

APOPTOSIS; ARTICLE; AUTOPSY; BIRTH WEIGHT; BRAIN DAMAGE; CELL DENSITY; CELL PROLIFERATION; CELL SIZE; CLINICAL ARTICLE; CONTROLLED STUDY; DENTATE GYRUS; DENTATE HILUS; GESTATIONAL AGE; GLIOSIS; HIPPOCAMPAL CA1 REGION; HIPPOCAMPAL CA2 REGION; HIPPOCAMPAL CA3 REGION; HIPPOCAMPUS; HISTOPATHOLOGY; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; INFANT; MYELINATION; NERVE CELL; NEUROFILAMENT; PREMATURITY; PRENATAL CARE; RETROSPECTIVE STUDY; DRUG EFFECT; HISTOLOGY; METABOLISM; NEWBORN;

MACACA MULATTA; MUS;

GLIAL FIBRILLARY ACIDIC PROTEIN; GLUCOCORTICOIDS; HIPPOCAMPUS; HUMANS; INFANT, NEWBORN; INFANT, PREMATURE; NEUROFILAMENT PROTEINS; NEURONS; VIMENTIN;

EID: 84858766202     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0033369     Document Type: Article

References (39)

1. Roberts D, Dalziel S, (2006) Antenatal corticosteroids for accelerating fetal lung maturation for women at risk of preterm birth. Cochrane Database Syst Rev 3 CD004454.
2. Meijer OC, de Kloet ER, (1998) Corticosterone and serotonergic neurotransmission in the hippocampus: functional implications of central corticosteroid receptor diversity. Crit Rev Neurobiol 12: 1-20.
3. Liggins GC, (1994) The role of cortisol in preparing the fetus for birth. Reprod Fertil Dev 6: 141-150.
4. Huang WL, Beazley LD, Quinlivan JA, Evans SF, Newnham JP, et al. (1999) Effect of corticosteroids on brain growth in fetal sheep. Obstet Gynecol 94: 213-218.
5. Jobe AH, Wada N, Berry LM, Ikegami M, Ervin MG, (1998) Single and repetitive maternal glucocorticoid exposures reduce fetal growth in sheep. Am J Obstet Gynecol 178: 880-885.
6. Kanagawa T, Tomimatsu T, Hayashi S, Shioji M, Fukuda H, et al. (2006) The effects of repeated corticosteroid administration on the neurogenesis in the neonatal rat. Am J Obstet Gynecol 194: 231-238.
7. French NP, Hagan R, Evans SF, Godfrey M, Newnham JP, (1999) Repeated antenatal corticosteroids: size at birth and subsequent development. Am J Obstet Gynecol 180: 114-121.
8. Abbasi S, Hirsch D, Davis J, Tolosa J, Stouffer N, et al. (2000) Effect of single versus multiple courses of antenatal corticosteroids on maternal and neonatal outcome. Am J Obstet Gynecol 182: 1243-1249.
9. Dirnberger DR, Yoder BA, Gordon MC, (2001) Single versus repeated-course antenatal corticosteroids: outcomes in singleton and multiple-gestation pregnancies. Am J Perinatol 18: 267-267.
10. Murphy KE, Hannah ME, Willan AR, Hewson SA, Ohlsson A, et al. (2008) MACS Collaborative Group, Multiple courses of antenatal corticosteroids for preterm birth (MACS): a randomised controlled trial. Lancet 372: 2143-2151.
11. Crowther CA, Haslam RR, Hiller JE, Doyle LW, Robinson JS, (2006) Australasian Collaborative Trial of Repeat Doses of Steroids (ACTORDS) Study Group, Neonatal respiratory distress syndrome after repeat exposure to antenatal corticosteroids: a randomised controlled trial. Lancet 367: 1913-1919.
12. Wapner RJ, Sorokin Y, Thom EA, Johnson F, Dudley DJ, et al. (2006) National Institute of Child Health and Human Development Maternal Fetal Medicine Units Network, Single versus weekly courses of antenatal corticosteroids: evaluation of safety and efficacy. Am J Obstet Gynecol 195: 633-642.
13. Guinn DA, Atkinson MW, Sullivan L, Lee M, MacGregor S, et al. (2001) Single vs weekly courses of antenatal corticosteroids for women at risk of preterm delivery: A randomized controlled trial. JAMA 286: 1581-1587.
14. De Kloet ER, Rosenfeld P, Van Eekelen JA, Sutanto W, Levine S, (1988) Stress, glucocorticoids and development. Prog Brain Res 73: 101-120.
15. Olton DS, Walker JA, Gage FH, (1978) Hippocampal connections and spatial discrimination. Brain Res 139: 295-308.
16. Eichenbaum H, Otto T, Cohen NJ, (1992) The hippocampus-what does it do? Behav Neural Biol 57: 2-36.
17. Epstein MF, Farrell PM, Sparks JW, Pepe G, Driscoll SG, et al. (1977) Maternal betamethasone and fetal growth and development in the monkey. Am J Obstet Gynecol 127: 261-263.
18. Uno H, Lohmiller L, Thieme C, Kemnitz JW, Engle MJ, et al. (1990) Brain damage induced by prenatal exposure to dexamethasone in fetal rhesus macaques. I. Hippocampus. Brain Res Dev Brain Res 53: 157-167.
19. Noorlander CW, Noorlander CW, De Graan PNE, Visser GHA, (2005) Effects of antenatal glucocorticoid treatment on fetal development. pp. 72-82 Antenatal glucocorticoid treatment affects hippocampal development in mice Febodruk B.V. ISBN 90-9019918-7.
20. Noorlander CW, Visser GH, Ramakers GM, Nikkels PG, De Graan PN, (2008) Prenatal corticosteroid exposure affects hippocampal plasticity and reduces lifespan. Dev Neurobiol 68: 237-246.
21. Visser GH, Eilers PH, Elferink-Stinkens PM, Merkus HM, Wit JM, (2009) New Dutch reference curves for birthweight by gestational age. Early Hum Dev 85: 737-744.
22. Korteweg FJ, Gordijn SJ, Timmer A, Erwich JJHM, Bergman KA, Bouman K, Ravise JM, Heringa MP, Holm JP, (2006) The Tulip classification of perinatal mortality: introduction and multidisciplinary inter-rater agreement. BJOG 113 (4): 393-401.
23. Groenendaal F, Lammers H, Smit D, Nikkels PG, (2006) Nitrotyrosine in brain tissue of neonates after perinatal asphyxia. Arch Dis Child Fetal Neonatal Ed 91: F429-33.
24. Scholzen T, Gerdes J, (2000) The Ki-67 protein: from the known and the unknown. J Cell Physiol 182: 311-322.
25. Sumi SM, Truog WE 3rd, Kessler DM, (1984) Maternal corticosteroid therapy and the fetal brain in experimental hyaline membrane disease. Pediatr Res 18: 440-444.
26. Scheepens A, Van de Waarenburg M, Van den Hove D, Blanco CE, (2003) A single course of prenatal betamethasone in the rat alters postnatal brain cell proliferation but not apoptosis. J Physiol 552: 163-175.
27. Adamo M, Werner H, Farnsworth W, Roberts CT Jr, Raizada M, et al. (1988) Dexamethasone reduces steady state insulin-like growth factor I messenger ribonucleic acid levels in rat neuronal and glial cells in primary culture. Endocrinology 123: 2565-2570.
28. Schaaf MJ, Hoetelmans RW, de Kloet ER, Vreugdenhil E, (1997) Corticosterone regulates expression of BDNF and trkB but not NT-3 and trkC mRNA in the rat hippocampus. J Neurosci Res 48: 334-341.
29. Molteni R, Fumagalli F, Magnaghi V, Roceri M, Gennarelli M, et al. (2001) Modulation of fibroblast growth factor-2 by stress and corticosteroids: from developmental events to adult brain plasticity. Brain Res Brain Res Rev 37: 249-258.
30. Wagner JP, Black IB, DiCicco-Bloom E, (1999) Stimulation of neonatal and adult brain neurogenesis by subcutaneous injection of basic fibroblast growth factor. J Neurosci 19: 6006-6016.
31. Aberg MA, Aberg ND, Hedbacker H, Oscarsson J, Eriksson PS, (2000) Peripheral infusion of IGF-I selectively induces neurogenesis in the adult rat hippocampus. J Neurosci 20: 2896-2903.
32. Murphy DJ, (2001) Effect of antenatal corticosteroids on postmortem brain weight of preterm babies. Early Hum Dev 63 (2): 113-22.
33. MacArthur BA, Howie RN, Dezoete JA, Elkins J, (1982) School progress and cognitive development of 6-year-old children whose mothers were treated antenatally with betamethasone. Pediatrics 70: 99-105.
34. Schmand B, Neuvel J, Smolders-de Haas H, Hoeks J, Treffers PE, et al. (1990) Psychological development of children who were treated antenatally with corticosteroids to prevent respiratory distress syndrome. Pediatrics 86: 58-64.
35. Dessens AB, Haas HS, Koppe JG, (2000) Twenty-year follow-up of antenatal corticosteroid treatment. Pediatrics 105: E77.
36. Dalziel SR, Rea HH, Walker NK, Parag V, Mantell C, et al. (2006) Long term effects of antenatal betamethasone on lung function: 30 year follow up of a randomised controlled trial. Thorax 61: 678-683.
37. Dalziel SR, Lim VK, Lambert A, McCarthy D, Parag V, et al. (2005) Antenatal exposure to betamethasone: psychological functioning and health related quality of life 31 years after inclusion in randomised controlled trial. BMJ 331: 665.
38. French NP, Hagan R, Evans SF, Mullan A, Newnham JP, (2004) Repeated antenatal corticosteroids: effects on cerebral palsy and childhood behavior. Am J Obstet Gynecol 190: 588-595.
39. Barrington KJ, (2001) The adverse neuro-developmental effects of postnatal steroids in the preterm infant: a systematic review of RCTs. BMC Pediatr 1: 1.