Autoimmunity and graves disease

Clinical Pharmacology and Therapeutics

Volumn 91, Issue 4, 2012, Pages 577-579

  Bahn, R S ^a  

^a MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHORIONIC GONADOTROPIN RECEPTOR ANTAGONIST; CORTICOSTEROID; HORMONE INHIBITOR; HORMONE RECEPTOR BLOCKING AGENT; LUTEINIZING HORMONE ANTAGONIST; METHOTREXATE; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 5C9; MONOCLONAL BLOCKING K1-70; RADIOACTIVE IODINE; RITUXIMAB; THIAMAZOLE; THYROTROPIN; THYROTROPIN RECEPTOR; THYROTROPIN RECEPTOR ANTIBODY; UNCLASSIFIED DRUG;

AGRANULOCYTOSIS; ANTIBODY DEPENDENT CELLULAR CYTOTOXICITY; AUTOIMMUNE HEMOLYTIC ANEMIA; AUTOIMMUNITY; BIOLOGICAL THERAPY; COMPLEMENT DEPENDENT CYTOTOXICITY; DECOMPRESSION SURGERY; DRUG MECHANISM; DRUG WITHDRAWAL; ENDOCRINE OPHTHALMOPATHY; GRAVES DISEASE; HORMONE SUBSTITUTION; HUMAN; LIVER TOXICITY; POLYARTERITIS NODOSA; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; RECURRENCE RISK; REMISSION; REVIEW; RHEUMATOID ARTHRITIS; SJOEGREN SYNDROME; SYSTEMIC LUPUS ERYTHEMATOSUS; THYROIDECTOMY; TREATMENT OUTCOME;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODIES, MONOCLONAL, MURINE-DERIVED; GRAVES DISEASE; GRAVES OPHTHALMOPATHY; HUMANS; RECEPTORS, THYROTROPIN;

EID: 84858759743     PISSN: 00099236     EISSN: 15326535     Source Type: Journal    
DOI: 10.1038/clpt.2012.10     Document Type: Review

References (5)

1. Bahn, R.S. et al. Hyperthyroidism and other causes of thyrotoxicosis: management guidelines of the American Thyroid Association and American Association of Clinical Endocrinologists. Thyroid 20, 593-646 (2011).
2. Bahn, R.S. Graves' ophthalmopathy. N. Engl. J. Med. 362, 726-738 (2010).
3. Sanders, J. et al. A human monoclonal autoantibody to the thyrotropin receptor with thyroid-stimulating blocking activity. Thyroid 18, 735-746 (2008). (Pubitemid 352009924)
4. Neumann, S. et al. A new small-molecule antagonist inhibits Graves' disease antibody activation of the TSH receptor. J. Clin. Endocrinol. Metab. 96, 548-554 (2011).
5. Hegedus, L., Smith, T.J., Douglas, R.S. & Nielsen, C.H. Targeted biological therapies for Graves' disease and thyroid-associated ophthalmopathy. Focus on B-cell depletion with rituximab. Clin. Endocrinol. 74, 1-8 (2011).