Evaluation in broilers of the probiotic properties of Pichia pastoris and a recombinant P. pastoris containing the Clostridium perfringens alpha toxin gene

Veterinary Microbiology

Volumn 156, Issue 3-4, 2012, Pages 448-451

  Gil de los Santos, João Rodrigo ^a   Storch, Otávio Brod ^a   Fernandes, Cristina Gevehr ^a   Gil Turnes, Carlos ^a  

^a FEDERAL UNIVERSITY OF PELOTAS   (Brazil)

Author keywords

Alpha toxin; Avian necrotic enteritis; Clostridium perfringens; Pichia pastoris; Probiotic; Recombinant pichia pastoris

Indexed keywords

BACTERIAL TOXIN; CLOSTRIDIUM PERFRINGENS TYPE A ALPHA TOXIN; PROBIOTIC AGENT; UNCLASSIFIED DRUG;

ARTICLE; BACILLUS CEREUS; BODY WEIGHT; BROILER; CLOSTRIDIUM PERFRINGENS TYPE A; CONTROLLED STUDY; FEMALE; HISTOLOGY; IMMUNITY; NONHUMAN; PICHIA PASTORIS; SEROCONVERSION; WEIGHT GAIN;

ANIMAL FEED; ANIMAL NUTRITIONAL PHYSIOLOGICAL PHENOMENA; ANIMALS; BACILLUS CEREUS; BACTERIAL TOXINS; CALCIUM-BINDING PROTEINS; CHICKENS; CLOSTRIDIUM PERFRINGENS; DIETARY SUPPLEMENTS; FEMALE; PICHIA; PROBIOTICS; TYPE C PHOSPHOLIPASES; WEIGHT GAIN;

AVES; BACILLUS CEREUS BIOVAR TOYOI; CLOSTRIDIUM PERFRINGENS; PICHIA PASTORIS;

EID: 84858751326     PISSN: 03781135     EISSN: 18732542     Source Type: Journal    
DOI: 10.1016/j.vetmic.2011.11.019     Document Type: Article

References (27)

1. Bollok M., Resina D., Valero F., Ferrer P. Recent patents on the Pichia Pastoris expression system: expanding the toolbox for recombinant protein production. Recent Pat. Biotechnol. 2009, 3:192-201.
2. Chen C.M., Cheng W.T.K., Chang Y.C., Chang T.J., Chen H.L. Growth enhancement of fowls by dietary administration of recombinant yeast cultures containing enriched growth hormones. Life Sci. 2000, 67:2102-2115.
3. Conceição F.R., Zani J.L., Gil-Turnes C. Effect of the probiotic CenBiot on the humoral response to an Escherichia coli bacterin. Food Agric. Immunol. 2000, 14:135-140.
4. Coppola M.M., Gil-Turnes C. Probióticos e resposta immune. Cienc. Rural 2004, 34:1297-1303.
5. Coppola M.M., Conceição F.R., Gil-Turnes C. Effect of Saccharomyces boulardii and Bacillus cereus var. toyoii on the humoral and cellular response of mice to vaccines. Food Agric. Immunol. 2005, 16:213-219.
6. Council of European Union, 2003. Council regulation on the authorization of the additive avilamycin in feeding stuffs. Retrieved 17.10.03, from Council of European Union. http://register.consilium.eu.int/pdf/en/03/st06/st06120en03.pdf.
7. Dahiya J.P., Wilkie D., Van Kessel A., Drew M. Potential strategies for controlling necrotic enteritis in broiler chickens in post-antibiotic era. Anim. Feed Sci. Technol. 2006, 129:60-88.
8. Engström B.E., Fermér C., Lindberg A., Saarinen E., Båverud V., Gunnarsson A. Molecular typing of isolates of Clostridium perfringens from healthy and diseased poultry. Vet. Microbiol. 2003, 94:225-235.
9. Gil de los Santos, J.R., 2007. Construction and evaluation of Clostridium perfringens A recombinant α toxin vaccines. Doctor of Sciences Thesis, Universidade Federal de Pelotas, Brazil. http://www.capes.gov.br/servicos/banco-de-teses.
10. Gil de los Santos J.R., Gil-Turnes C. Probióticos em avicultura. Cienc. Rural 2005, 35:741-747.
11. Gil de los Santos J.R., Storch O.B., Gil-Turnes C. Bacillus cereus var. toyoii and Saccharomyces boulardii increased feed efficiency in broilers infected with Salmonella enteritidis. Br. Poult. Sci. 2005, 46:494-497.
12. Gil-Turnes C., Dos Santos A.F., Da Cruz F.W., Monteiro A.V. Properties of the Bacillus cereus strain used in probiotic CenBiot. Braz. J. Microbiol. 1999, 30:11-14.
13. Gil-Turnes C., Conceição F.R., Gil de los Santos J.R. Bacillus cereus var. Toyoi improves feed efficiency and health in animals. Int. J. Probiotics Prebiotics 2007, 2:21-28.
14. Kaldhusdal M. Maintaining gut health in meat-type poultry without antibacterial growth promoters and ionophores. 14th European Symposium on Poultry Nutrition, Lillehammer, Norway. Proceedings 2003 2003, 151-157. (accessed 08.12.04).
15. Kumprechtova D., Zobac P., Kumprecht I. The effect of Saccharomyces cerevisiae Sc47 on chicken broiler performance and nitrogen output. Chzech J. Anim. Sci. 2000, 45:169-177.
16. Lara-Flores M., Olvera-Novoa M.A., Guzmán-Méndez B.E., López-Madrid W. Use of the bacteria Streptococcus faecium and Lactobacillus acidophilus and the yeast Saccharomyces cerevisiae as growth promoters in Nile tilapia (Oreochromis niloticus). Aquaculture 2003, 216:193-201.
17. Li P., Anumanthan A., Gao X.G., Ilangovan K., Suzara V.V., Düzgüneş N., Renugopalakrishnan V. Expression of recombinant proteins in Pichia pastoris. Appl. Biochem. Biotechnol. 2007, 142:105-124.
18. Lovland A., Kaldhusdal M. Severely impaired production performance in broiler flocks with high incidence of Clostridium perfringens-associated hepatitis. Avian Pathol. 2001, 30:73-81.
19. Macauley-Patrick S., Fazenda M.L., McNeil B., Harvey L.M. Heterologous protein production using the Pichia pastoris expression system. Yeast 2005, 22:249-270.
20. Patterson J.A., Burkholder K.M. Application of prebiotics and probiotics in poultry production. Poult. Sci. 2003, 82:627-631.
21. Phillips R. The antibiotic-probiotic dance: role in food safety. 13TH Western Meeting of Poultry Clinicians and Pathologists. Proceedings 2002, (accessed 27.01.04).
22. Ramón A., Marín M. Advances in the production of membrane proteins in Pichia pastoris. Biotechnol. J. 2011, 6:700-706.
23. Swann Committee BVA and RCVS evidence to the Swann Committee. Vet. Rec. 1969, January 25:91-92.
24. Thompson D.R., Parreira V.R., Kulkarni R.R., Prescott J.F. Live attenuated vaccine-based control of necrotic enteritis of broiler chickens. Vet. Microbiol. 2006, 113:25-34.
25. Van der Sluis W. Clostridial enteritis is an often underestimated problem. World Poult. 2000, 16:42-43.
26. Wang W., Gu Q. Effect of probiotic on growth performance and digestive enzyme activity of Arbor Acres broilers. Res. Vet. Sci. 2010, 89:163-167.
27. Zani J.L., Cruz F.W., Santos A.F., Gil-Turnes C. Effect of probiotic CenBiot on the control of diarrhea and feed efficiency in pigs. J. Appl. Microbiol. 1998, 84:68-71.