Oral nutritional support in malnourished elderly decreases functional limitations with no extra costs

Clinical Nutrition

Volumn 31, Issue 2, 2012, Pages 183-190

  Neelemaat, Floor ^a   Bosmans, Judith E ^b   Thijs, Abel ^a   Seidell, Jaap C ^b   van Bokhorst de van der Schueren, Marian A E ^a  

^a VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^b UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

Cost effectiveness; Elderly; Functional limitations; Malnutrition; Patients

Indexed keywords

CALCIUM; VITAMIN D;

ADULT; AGED; ARTICLE; CALORIC INTAKE; CONTROLLED STUDY; COST EFFECTIVENESS ANALYSIS; COST UTILITY ANALYSIS; DIET SUPPLEMENTATION; FEMALE; HEALTH CARE COST; HEALTH CARE UTILIZATION; HOSPITAL ADMISSION; HUMAN; MAJOR CLINICAL STUDY; MALE; MALNUTRITION; NUTRIENT LIMITATION; NUTRITIONAL COUNSELING; NUTRITIONAL SUPPORT; PHYSICAL ACTIVITY; PROTEIN DIET; QUALITY ADJUSTED LIFE YEAR; QUALITY OF LIFE; RANDOMIZED CONTROLLED TRIAL; VITAMIN SUPPLEMENTATION;

ADMINISTRATION, ORAL; AGED; AGED, 80 AND OVER; CALCIUM, DIETARY; CHOLECALCIFEROL; COST-BENEFIT ANALYSIS; DIETARY PROTEINS; DIETARY SUPPLEMENTS; ENERGY INTAKE; FEMALE; FOLLOW-UP STUDIES; HOSPITALIZATION; HUMANS; INTERVENTION STUDIES; INTERVIEWS AS TOPIC; MALE; MALNUTRITION; MIDDLE AGED; NUTRITIONAL SUPPORT; PATIENT COMPLIANCE; PATIENT DISCHARGE; QUALITY OF LIFE; QUALITY-ADJUSTED LIFE YEARS; QUESTIONNAIRES; TREATMENT OUTCOME;

EID: 84858749423     PISSN: 02615614     EISSN: 15321983     Source Type: Journal    
DOI: 10.1016/j.clnu.2011.10.009     Document Type: Article

References (43)

1. Klipstein-Grobusch K., Reilly J.J., Potter J., Edwards C.A., Roberts M.A. Energy intake and expenditure in elderly patients admitted to hospital with acute illness. Br J Nutr 1995, 73:323-334.
2. Watson J.L. The prevalence of malnutrition in patients admitted to care of the elderly wards. Proc Nutr Soc 1999, 58.
3. Commission of the European Communities Confronting demographic change: a new solidarity between the generations 2005, Green Paper.
4. RIVM Research for man en environment health and disease 20-10-2010, Ref Type: Internet Communication. http://www.rivm.nl/en/healthanddisease.
5. CBS Statistics Netherlands population aging 20-10-2010, Ref Type: Internet Communication. http://www.cbs.nl/en-GB/menu/themas/dossiers/vergrijzing/publicaties/artikelen/archief/2010.
6. Flodin L., Svensson S., Cederholm T. Body mass index as a predictor of 1 year mortality in geriatric patients. Clin Nutr 2000, 19:121-125.
7. Martyn C.N., Winter P.D., Coles S.J., Edington J. Effect of nutritional status on use of health care recources by patients with chronic disease living in the community. Clin Nutr 1998, 17:119-123.
8. Payette H., Boutier V., Coulombe C., Gray-Donald K. Benefits of nutritional supplementation in free-living, frail, undernourished elderly people: a prospective randomized community trial. J Am Diet Assoc 2002, 102:1088-1095.
9. Elia M., Stratton R.J. The cost of disease-related malnutrition in the UK and economic considerations for the use of ONS in adults; Health economic report on malnutrition in the UK 2005, BAPEN, Ref Type: Report.
10. Ljungqvist O., Van G.A., Sanz M.L., de M.F. The European fight against malnutrition. Clin Nutr 2010, 29:149-150.
11. Stratton R.J., Green C.J., Elia M. Disease related malnutrition: an evidence-based approach to treatment 2003, CABI Publishing, Cambridge, pp. 1-34.
12. Stratton R.J., Green C.J., Elia M. Consequences of disease related malnutrition. Disease related malnutrition 2003, 113-155. CABI Publishing, Cambridge. R.J. Stratton, C.J. Green, M. Elia (Eds.).
13. Milne A.C., Avenell A., Potter J. Meta-analysis: protein and energy supplementation in older people. Ann Intern Med 2006, 144:37-48.
14. Arnaud-Battandier F., Malvy D., Jeandel C., Schmitt C., Aussage P., Beaufrère B., et al. Use of oral supplements in malnourished elderly patients living in the community: a pharmaco-economic study. Clin Nutr 2004, 23:1096-1103.
15. Baldwin C., Parsons T.J. Dietary advice and nutritional supplements in the management of illness-related malnutrition: systematic review. Clin Nutr 2004, 23:1267-1279.
16. Baldwin C., Parsons T., Logan S. Dietary advice for illness-related malnutrition in adults. Cochrane Database Syst Rev 2007, CD002008.
17. Milne A.C., Potter J., Vivanti A., Avenell A. Protein and energy supplementation in elderly people at risk from malnutrition (Review). Cochrane Database Syst Rev 2009, CD003288.
18. Neelemaat F., Thijs A., Seidell J.C., Bosmans J.E., van Bokhorst-de van der Schueren M.A. Study protocol: cost-effectiveness of transmural nutritional support in malnourished elderly patients in comparison with usual care. Nutr J 2010, 9:6.
19. Oostenbrink J.B., Koopmanschap M.A., Rutten F.F. Standardisation of costs: the Dutch Manual for Costing in economic evaluations. Pharmacoeconomics 2002, 20:443-454.
20. Oostenbrink J.B., Bouwmans C.A.M., Koopmanschap M.A., Rutten F.F.H. Guidelines for cost studies, methods and standard costs for economic evaluations in health care 2004, Dutch Health Insurance Council, Ref Type: Report.
21. Z-index G-standaard 2002, Z-index, The Hague, The Netherlands.
22. Statistics Netherlands/Centraal Bureau voor de statistiek 2010, Ref Type: Internet Communication.
23. Szende A., Oppe M., Devlin N. EQ-5D value sets: Inventory, Comparative review and User Guide 2007.
24. Lamers L.M., Stalmeier P.F., McDonnell J., Krabbe P.F., van Busschbach J.J. Measuring the quality of life in economic evaluations: the Dutch EQ-5D tariff. Ned Tijdschr Geneeskd 2005, 149:1574-1578.
25. Guralnik J.M., Ferrucci L., Simonsick E.M., Salive M.E., Wallace R.B. Lower-extremity function in persons over the age of 70 years as a predictor of subsequent disability. N Engl J Med 1995, 332:556-561.
26. Stel V.S., Smit J.H., Pluijm S.M., Visser M., Deeg D.J., Lips P. Comparison of the LASA Physical Activity Questionnaire with a 7-day diary and pedometer. J Clin Epidemiol 2004, 57:252-258.
27. Kriegsman D.M., Deeg D.J., van Eijk J.T., Penninx B.W., Boeke A.J. Do disease specific characteristics add to the explanation of mobility limitations in patients with different chronic diseases? A study in The Netherlands. J Epidemiol Community Health 1997, 51:676-685.
28. Puts M.T., Lips P., Deeg D.J. Static and dynamic measures of frailty predicted decline in performance-based and self-reported physical functioning. J Clin Epidemiol 2005, 58:1188-1198.
29. Guralnik J.M., Simonsick E.M., Ferrucci L., Glynn R.J., Berkman L.F., Blazer D.G., et al. A short physical performance battery assessing lower extremity function: association with self-reported disability and prediction of mortality and nursing home admission. J Gerontol 1994, 49:M85-M94.
30. Neelemaat F., Bosmans J.E., Thijs A., Seidell J.C., van Bokhorst-de van der Schueren M.A. Post-discharge nutritional support in malnourished elderly individuals improves functional limitations. J Am Med Dir Assoc 2011, 12:295-301.
31. Oostenbrink J.B., Al M.J. The analysis of incomplete cost data due to dropout. Health Econ 2005, 14:763-776.
32. Rubin D.B. Multiple imputation for nonresponse in surveys 1987, John Wiley & Sons, New York.
33. Burton A., Billingham L.J., Bryan S. Cost-effectiveness in clinical trials: using multiple imputation to deal with incomplete cost data. Clin Trials 2007, 4:154-161.
34. Efron B. Missing data, imputation and the bootstrap. J Am Stat Assoc 1994, 89:463-475. [abstr].
35. Black W.C. The CE plane: a graphic representation of cost-effectiveness. Med Decis Making 1990, 10:212-214.
36. Fenwick E., O'Brien B.J., Briggs A. Cost-effectiveness acceptability curves-facts, fallacies and frequently asked questions. Health Econ 2004, 13:405-415.
37. Edington J., Barnes R., Bryan F., Dupree E., Frost G., Hickson M., et al. A prospective randomised controlled trial of nutritional supplementation in malnourished elderly in the community: clinical and health economic outcomes. Clin Nutr 2004, 23:195-204.
38. McMurdo M.E., Price R.J., Shields M., Potter J., Stott D.J. Should oral nutritional supplementation be given to undernourished older people upon hospital discharge? A controlled trial. J Am Geriatr Soc 2009, 57:2239-2245.
39. Hampson G., Martin F.C., Moffat K., Vaja S., Sankaralingam S., Cheung J., et al. Effects of dietary improvement on bone metabolism in elderly underweight women with osteoporosis: a randomised controlled trial. Osteoporos Int 2003, 14:750-756.
40. Tidermark J., Ponzer S., Carlsson P., Söderqvist A., Brismar K., Tengstrand B., et al. Effects of protein-rich supplementation and nandrolone in lean elderly women with femoral neck fractures. Clin Nutr 2004, 23:587-596.
41. Woo J., Ho S.C., Mak Y.T., Law L.K., Cheung A. Nutritional status of elderly patients during recovery from chest infection and the role of nutritional supplementation assessed by a prospective randomized single-blind trial. Age Ageing 1994, 23:40-48.
42. Rasanen P., Roine E., Sintonen H., Semberg-Konttinen V., Ryynanen O.P., Roine R. Use of quality-adjusted life years for the estimation of effectiveness of health care: a systematic literature review. Int J Technol Assess Health Care 2006, 22:235-241.
43. Briggs A. Economic evaluation and clinical trials: size matters. BMJ 2000, 321:1362-1363.