Increased expression of Na,K-ATPase and a selective increase in phosphorylation at Ser-11 in the cortex of the 2-kidney, 1-clip hypertensive rat

American Journal of Hypertension

Volumn 25, Issue 4, 2012, Pages 487-491

  Kava, Lauren ^a   Rossi, Noreen F ^a   Mattingly, Raymond ^a   Yingst, Douglas R ^a  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

angiotensin II; blood pressure; blood volume; epithelial cells; hypertension; salt; sodium

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); ANGIOTENSIN II; BETA ACTIN; SERINE;

ANGIOTENSIN BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; IMMUNOBLOTTING; KIDNEY CORTEX; KIDNEY PROXIMAL TUBULE; MALE; MEAN ARTERIAL PRESSURE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; RENOVASCULAR HYPERTENSION; SODIUM ABSORPTION;

ACTINS; AMINO ACID SEQUENCE; ANGIOTENSIN II; ANIMALS; BLOOD PRESSURE; CONSTRICTION, PATHOLOGIC; HYPERTENSION, RENOVASCULAR; KIDNEY CORTEX; KIDNEY TUBULES, PROXIMAL; MALE; PHOSPHORYLATION; RATS; RATS, SPRAGUE-DAWLEY; RENAL ARTERY; SERINE; SODIUM-POTASSIUM-EXCHANGING ATPASE;

EID: 84858708557     PISSN: 08957061     EISSN: 19417225     Source Type: Journal    
DOI: 10.1038/ajh.2011.247     Document Type: Article

References (21)

1. Maliszewska-Scislo M, Chen H, Augustyniak RA, Seth D, Rossi NF. Subfornical organ differentially modulates baroreflex function in normotensive and two-kidney, one-clip hypertensive rats. Am J Physiol Regul Integr Comp Physiol 2008; 295:R741-R750.
2. Nyström HC, Jia J, Johansson M, Lambert G, Bergström G. Neurohormonal influences on maintenance and reversal of two-kidney one-clip renal hypertension. Acta Physiol Scand 2002; 175:245-251. (Pubitemid 34779428)
3. Prieto-Carrasquero MC, Botros FT, Pagan J, Kobori H, Seth DM, Casarini DE, Navar LG. Collecting duct renin is upregulated in both kidneys of 2-kidney, 1-clip goldblatt hypertensive rats. Hypertension 2008; 51:1590-1596.
4. Robertson JI, Morton JJ, Tillman DM, Lever AF. The pathophysiology of renovascular hypertension. J Hypertens Suppl 1986; 4:S95-103.
5. Yingst DR, Araghi A, Doci TM, Mattingly R, Beierwaltes WH. Decreased renal perfusion rapidly increases plasma membrane Na-K-ATPase in rat cortex by an angiotensin II-dependent mechanism. Am J Physiol Renal Physiol 2009; 297:F1324-F1329.
6. Aperia A, Holtbäck U, Syrén ML, Svensson LB, Fryckstedt J, Greengard P. Activation/deactivation of renal Na+,K(+)-ATPase: a final common pathway for regulation of natriuresis. FASEB J 1994; 8:436-439. (Pubitemid 24155957)
7. Bharatula M, Hussain T, Lokhandwala MF. Angiotensin II AT1 receptor/signaling mechanisms in the biphasic effect of the peptide on proximal tubular Na+,K+- ATPase. Clin Exp Hypertens 1998; 20:465-480. (Pubitemid 28269525)
8. Efendiev R, Budu CE, Cinelli AR, Bertorello AM, Pedemonte CH. Intracellular Na+ regulates dopamine and angiotensin II receptors availability at the plasma membrane and their cellular responses in renal epithelia. J Biol Chem 2003; 278:28719-28726. (Pubitemid 36935779)
9. Garvin JL. Angiotensin stimulates bicarbonate transport and Na+/K+ ATPase in rat proximal straight tubules. J Am Soc Nephrol 1991; 1:1146-1152.
10. Yingst DR, Massey KJ, Rossi NF, Mohanty MJ, Mattingly RR. Angiotensin II directly stimulates activity and alters the phosphorylation of Na-K-ATPase in rat proximal tubule with a rapid time course. Am J Physiol Renal Physiol 2004; 287:F713-F721. (Pubitemid 39280506)
11. Fekete A, Rosta K, Wagner L, Prokai A, Degrell P, Ruzicska E, Vegh E, Toth M, Ronai K, Rusai K, Somogyi A, Tulassay T, Szabo AJ, Ver A. Na+,K+-ATPase is modulated by angiotensin II in diabetic rat kidney-another reason for diabetic nephropathy? J Physiol (Lond) 2008; 586:5337-5348.
12. Guan S, Fox J, Mitchell KD, Navar LG. Angiotensin and angiotensin converting enzyme tissue levels in two-kidney, one clip hypertensive rats. Hypertension 1992; 20:763-767.
13. Cervenka L, Vanecková I, Husková Z, Vanourková Z, Erbanová M, Thumová M, Skaroupková P, Opocenský M, Malý J, Chábová VC, Tesar V, Bürgelová M, ViklickýO, Teplan V, Zelízko M, Kramer HJ, Navar LG. Pivotal role of angiotensin II receptor subtype 1A in the development of two-kidney, one-clip hypertension: study in angiotensin II receptor subtype 1A knockout mice. J Hypertens 2008; 26: 1379-1389.
14. Yingst DR, Doci TM, Massey KJ, Rossi NF, Rucker E, Mattingly RR. Angiotensin II stimulates elution of Na-K-ATPase from a digoxin-affinity column by increasing the kinetic response to ligands that trigger the decay of E2-P. Am J Physiol Renal Physiol 2008; 294:F990-F1000.
15. Braam B, Mitchell KD, Fox J, Navar LG. Proximal tubular secretion of angiotensin II in rats. Am J Physiol 1993; 264:F891-F898. (Pubitemid 23149720)
16. Ortiz RM, Graciano ML, Seth D, Awayda MS, Navar LG. Aldosterone receptor antagonism exacerbates intrarenal angiotensin II augmentation in ANG II-dependent hypertension. Am J Physiol Renal Physiol 2007; 293:F139-F147. (Pubitemid 47345012)
17. Cervenka L, Wang CT, Mitchell KD, Navar LG. Proximal tubular angiotensin II levels and renal functional responses to AT1 receptor blockade in nonclipped kidneys of Goldblatt hypertensive rats. Hypertension 1999; 33:102-107. (Pubitemid 29061849)
18. Therien AG, Blostein R. Mechanisms of sodium pump regulation. Am J Physiol, Cell Physiol 2000; 279:C541-C566.
19. Efendiev R, Pedemonte CH. Contrary to rat-type, human-type Na,K-ATPase is phosphorylated at the same amino acid by hormones that produce opposite effects on enzyme activity. J Am Soc Nephrol 2006; 17:31-38.
20. Akabane S, Natsume T, Matsushima Y, Deguchi F, Kuramochi M, Ito K. Alterations in renal Na+K+ATPase activity and [3H]ouabain binding in Goldblatt hypertensive rabbits. J Hypertens 1985; 7:913-922.
21. Féraille E, Béguin P, Carranza ML, Gonin S, Rousselot M, Martin PY, Favre H, Geering K. Is phosphorylation of the alpha1 subunit at Ser-16 involved in the control of Na,K-ATPase activity by phorbol ester-activated protein kinase C? Mol Biol Cell 2000; 11:39-50. (Pubitemid 30075504)